CN103517671A

CN103517671A - Method for determining standardised lighting, and associated device

Info

Publication number: CN103517671A
Application number: CN201280018843.3A
Authority: CN
Inventors: G·博伊; M·佩里克瓦; S·拉奎艾泽
Original assignee: PERITESCO
Current assignee: PERITESCO
Priority date: 2011-03-04
Filing date: 2012-03-01
Publication date: 2014-01-15
Anticipated expiration: 2032-03-01
Also published as: BR112013022128A2; EP2680751A1; WO2012120413A1; FR2972109A1; CN103517671B

Abstract

The invention relates to a method for determining the optimised lighting of an area of human skin for studying the surface condition thereof, the area of skin having raised areas, the lighting coming from a device comprising one or more light sources and generating shadow areas next to the raised areas, the method including the following steps: defining a first parameter P1 according to the contrast between the luminosity inside the shadow areas and the luminosity outside the shadow areas; defining a second parameter P2 in accordance with the uniformity of the luminosity; defining a cost function C according to the first parameter P1 and/or to the second parameter P2; and searching for a maximum for the cost function C.

Description

The method of settling the standard illumination and the device being associated

The present invention relates to make it possible to provide high-quality and standardized illumination to allow the device of its apparent condition of research on skin area." high-quality illumination " refers to and allows to obtain the spatially uniform on the area-of-interest limiting in the research aspect colorimetric simultaneously, and the illumination of the alignment features of the projection of permission demonstration skin histology.

In beauty treatment and medical domain, the inspection of skin surface state is the key step of dermatological clinical examination.Among this surperficial different characteristic, about the most information of its state, be its projection, its color and its reflection.The demonstration of these features will be depended on used illumination.

Importantly can realize interior the observation to approach better the real conditions of live body of body of the type.

FR2589242 has described the system that shows skin projection based on impression.Yet this system is intended to the research of inertia sample and does not allow to study in vivo the state of skin surface.

FR2826857 has described general skin illuminator.Yet the measurement of the protrusion features of skin histology is not the target of proposed device and the demonstration of this feature is not clearly mentioned to this measurement at all.

Good illumination uniformity on area-of-interest is for avoiding impact evaluation to be absolutely necessary.Can consider two extreme lighting conditions.Isotropic illumination can for example provide and allow the correctly excellent homogeneity on area-of-interest of evaluate color, but can wipe projection by eliminating projection, thereby causes the evaluation of this rear parameter to become impossible.For manifesting the effective ways of projection, comprise generation projection.The illumination meeting of skimming over is by projection being maximized and therefore setting off this projection by contrast, but medium uniformity can be provided on studied region, thereby causes the evaluation of the color difficulty that becomes.Suitable is to produce the illumination of simultaneously combining these two features.

In addition, suitable is the reflectance signature of considering observed tissue.Preferably avoid the visible direct reflection of light source to avoid interference evaluation.

Many skin areas can have benefited from the inspection with the type illumination.Can mention, exhaustively non-, the region of forearm, arm, buccal, lower limb, eyelet and eye pouch, the profile of eyes.From general angle, in some cases, any region of health can have the benefit with the illumination of such type observed (any dyskeratotic observation).

In order to contribute to observe, illuminator is placed on skin histology.For optimal viewing, required illumination described above retrains the constraint of adding to about the physical features of device, the size of device and weight should be low to the state of skin histology is not applied to any impact as much as possible.Dimension aspect is also important for allowing described device to lay on whole human regions.

The object of the invention is in conjunction with above-described all conditions, to be provided for studying the colorimetric aspect of the skin area on whole human bodies and the optimal illumination of projection.

According to the present invention, the optimization illumination in a kind of definite human skin region is to allow the method for its apparent condition of research, this skin area has raised areas, this illumination carrys out the device of self-contained one or more light sources and near raised areas, produces shadow region, it is characterized in that comprising the following steps:

-according to the contrast between the luminosity of inside, shadow region and the luminosity of outside, shadow region, limit the first parameter P1,

-according to the uniformity of luminosity, limit the second parameter P2,

-according to the first parameter P1 and/or the second parameter P2, limit cost function C,

The maximum of-searching cost function C.

Described cost function can be restricted to the form of C=a*P1+b*P2, and wherein a and b are real number.

The maximum of finding cost function C can comprise the step of wherein studying the variation of C according to the variation of at least one following parameters: the type of light source, light source with respect to the height (h) of skin, light source with respect to the distance (e) of skin and each light source the light angle (α) with respect to considered skin area.

The present invention has also inquired into the device in illumination human skin region, and it has at least one following feature that the method according to this invention is determined: light source with respect to the height (h) of skin, light source with respect to the distance (e) of skin and each light source the light angle (α) with respect to considered skin area.

Advantageously, at least one light source is point-like.

This device can comprise a window for observing.

This device can comprise the camera chain that is fixed to its structure.

This device can be connected to photography is recorded to the system that Bing Xiang remote subscriber sends.

This device can comprise makes this device on the minimized plate leaning against on skin of the impact of measured zone.

This plate can comprise allow this device around be fixed to skin outer member automatic centring to central module.

This device can comprise the projection parts of light that can emitting structural.

This device can comprise measures catoptrical measurement component.

This device can comprise the optical character projection parts of auxiliary reorientation.

This device can comprise the sensor of one or more physical attributes of measuring skin.

In the description of other features and advantages of the present invention by carry out with reference to accompanying drawing below preferred but without any the embodiment of limited features, become clear.In these figure:

Fig. 1 is perspective diagram, illustrates according to the parts of skin of the illuminated plane P of method of the present invention,

Fig. 2 is the schematic diagram of example that the light intensity distributions of point source is shown,

Fig. 3 illustrates the schematic diagram of the enforcement of the method according to this invention by having the example of the linear block of 3 point sources,

Fig. 4 illustrates photodistributed schematic diagram, and described light distributes and produces the combination from 3 light sources that change with its spacing,

Fig. 5 is for d=0Tu4 cross section,

Fig. 6 is for the Tu4 cross section that approaches 40 d,

Fig. 7 is the Tu4 cross section for d=100,

Fig. 8 is in the situation that have 2 views that module is similar to Fig. 3 with the special embodiment of 2 point sources,

Fig. 9 a is to illustrate the photodistributed schematic diagram obtaining for 2 groups of different geometric parameters with 9b,

Figure 10 illustrates to use the schematic diagram that shows projection according to device of the present invention,

Figure 11 a and 11b illustrate in order to show for the contrast of 2 groups of different parameters and the schematic diagram of the example of the light stream obtaining,

Figure 12 and 13 is the perspective views according to device of the present invention,

Figure 14 is the perspective view that illustrates the camera chain on the shell of the device that is fixed on Figure 12 and 13,

Figure 15 is the view similar to Figure 14, illustrates the camera chain that is independent of shell,

Figure 16 is the view similar to Figure 12 with the part thrown off, and illustrates the existence of area-of-interest edge high scale chi,

Figure 17 is the view similar to Figure 16, illustrates around the existence of the fixing color scale of area-of-interest,

Figure 18 is the view similar to Figure 16, illustrates and has for carried out the existence of rotation disc of the color scale of colorimetric evaluation by observer,

Figure 19 is the top view of the device of Figure 12, illustrates the existence of the amplifying device of area-of-interest,

Figure 20 is the view similar to Figure 12 with less ratio, illustrates the existence of reorientation auxiliary projection module, and

Figure 21 be in the situation in using the auxiliary external module of reorientation according to the perspective view of device of the present invention.

It is upper that the plane of the skin histology that consideration is studied can be positioned at datum plane P, based on this datum plane P, will describe feature of the present invention (comparison diagram 1).Area-of-interest can be any shape.In the embodiment providing, consider the rectangular region (comparison diagram 1) centering around an O in the document.

Light is provided by one or more modules.Each module by a plurality of can be that the light source of point-like, linearity or plane forms.These light sources can be incandescent lamp bulb, neon bulb, LED bulb or discharge bulb.The shape of module can be linear, circular, plane or any shape.

In this manual, consider that module is comprised of point source.The enforcement of constraint described above is by considering that the light of each light source distributes and carries out at the optimal geometrical parameter being oppositely arranged between light source and between module for area-of-interest by determining.

The photodistributed example of light source shows on Fig. 2.Use the single light source of the type obviously to produce inhomogeneous illumination.If it arranges the combination of Different Light incorrect words and also may provide light source heterogeneous.The present invention uses such light source: its interval, with respect to studied surperficial height and with respect to the light angle of studied normal to a surface, not only allowed uniform illumination but also allowed the demonstration of projection.

In a special embodiment, light source is white.By the type of wavelength used in the present invention, not restrictive and can be from ultra-violet (UV) band to ultrared.

In order to meet condition described above, first studied the distribution that produces the combination of the Different Light in module.By the hypothesis based on 3 light sources, Fig. 3 has shown an embodiment, these 3 light sources are by position and the parallel plane same straight line studied, there is the interval between each light source that is labeled as d as represented in Fig. 3, and each light source has Gauss's luminosity and distributes, and the direction of its maximum intensity is schematically illustrated by dotted arrows.The illumination direction of each light source is supposed, is parallel in the present embodiment.The light of whatsoever type that this reasoning can be applied to have the illumination direction of any direction distributes.Observe on Fig. 3 the synthetic illumination on the straight line that is labeled as L that line parallel is set with light source.

On Fig. 4 to 7, represented this synthetic illumination.Visible for little interval, the combination of 3 light sources produces the illumination of gaussian shape.The interval of light source allows to provide the distribution being crushed, until become best distribution around at d=40, for d=40, illumination can be constant on the horizontal segment of Breadth Maximum.Be greater than this optimal spacing, by three Gaussian peaks that recover gradually corresponding to each light source.

Note, this distributes for above-described light especially apart from d=40 is best.The in the situation that of different distributions, this value can change.

The present invention has arranged Different Light to obtain this optimum state.

Note, for the application of the described the method for module, can be popularized for several modules.Therefore it is contemplated that around arranging of several modules in region to be studied and can distinguish or not distinguish place bright.

In a special embodiment, 2 modules that each is comprised of 2 point sources are arranged on the both sides in region as shown in Figure 8.This arranges and allows to show projection along privileged direction.

In other possible configuration, arrange for 90 ° of 4 modules and allow along 2 privileged direction research projections.

Once produce uniformity of light by the module of optimizing, the setting of each module of using is just optimised.The parameter of studying is each module with respect to the height h of reference surface P, with respect to spacing e and the light angle α of an O.By these parametric representations on Fig. 8.

The demonstration of projection and the generation of Uniform Illumination are by height best for the area-of-interest with respect to being studied and angle of incidence, each module to be set to carry out.

The optimum of each parameter definite is that the display quality by the illumination uniformity from point of theory research area-of-interest and projection carries out.This research is carried out by means of optical analog instrument and is allowed for its impact of final result on obtain illumination of each parameter simulation.

Certainly, can come sample plot to verify these notional results by the enforcement of device.

For determining that the methodology that the optimum of h, e and α is used can be repetition.From underlying parameter, start to test.By or based on visual method or for example, based on representing that inhomogeneity designator (photodistributed interval type) studies the impact of each parameter on result.Use the new test etc. of the parameter through upgrading that allow to optimize illumination until result is best.Can use the optimized algorithm of simplex or Levenberg-Marquardt type.

The method is combined with experienced doctor's observation, and this doctor this time verifies and instructs these parameters with the clinical method of obtained result.Optimum power is a feature especially, and it cannot be only by considering that the real observation of user is optimized.

Show the example of the light stream obtaining for the special embodiment with 2 modules on for inhomogeneity Fig. 9 A and 9B.In the first situation of Fig. 9 A, notice low-quality illumination uniformity, there is central maximum luminosity point.In the optimised the second situation of the wherein parameter of Fig. 9 B, notice the larger uniformity with lower diminuendo.

Once regulate uniformity, just adjusted parameter so that the best image of projection.This demonstration by research the contrast between the projection of the parallelepiped at measured zone center carry out, as represented in Figure 10.Figure 11 A and 11B represent an example of obtained light stream.In shown example, can be observed 0.67 contrast in the first situation of Figure 11 A, and in the illumination of the second configuration of Figure 11 B, in described special embodiment, produce 0.63 contrast.

Can, by using this contrast level parameter, repetition methods described above be applied to the optimization of illumination.Herein, checking and optimization are also by combining to carry out with experienced clinician's observation by measuring.

Can note, optimization can be by succession considering uniformity and contrast, or by consider that 2 parameters carry out simultaneously.

Structure of the present invention is completely around area-of-interest, thereby permission Jiang Gai region and exterior lighting are isolated.

In having the embodiment of the relative illumination of 2 covers, described structure can be the shell that has example parallelepiped shape as shown in figure 12.

The support of shell on skin realizes by special plate.This plate can be one around the simple flat surface of area-of-interest, as represented in Figure 13, or can be also F-SP to allow around reclining to the special device Dui center of skin.This special device can be for example the ring using in the skin measurement with Laser Scanning Confocal Microscope.

Plate and shell also can have the inward flange of F-SP to adapt to best the region that its form is not plane.In the example in buccal region, the edge of introversion and plate allow abutment surface better so as to guarantee area-of-interest and device between Continuous Contact.Can also adopt deformable flex plate.

The observation of area-of-interest can be carried out in two ways.

In the first situation, observation is direct and user is seen area-of-interest by the window of opening up on shell, as represented in Figure 12.

In the second situation, photographic attachment be positioned at shell above.Can use several solutions in this case.

Can, by camera chain, according to first embodiment, be fixed on shell, as represented in Figure 14.In this case, the weight of system is born by the shell on the tissue regions around observed region.

In the second embodiment, camera chain is not fixed on shell.In this case, have around the external frame of the support of shell and allow in the work of the constant distance place of area-of-interest, as represented in Figure 15.

Photographic attachment can be photographing unit, compact photographic instrument or reflection photographic instrument.

If the device using is photographing unit, can realize so directly visual on screen externally, there is the probability of direct use dimensional measurement instrument or colorimetric appraisal tool.

Use therein in the situation of photographic attachment, can be connected to the external equipment that allows record and photograph to user transmission at a distance.Transmission can be wired, can be also wireless.

In embodiment further, instrument can be arranged on to enclosure and evaluate contributing to.

Can be by rule, referring to Figure 16, be positioned in illumination plane with evaluation Example as the size of speckle or cicatrix.

The fixing color scale through calibration can also be positioned on the edge of area-of-interest or inner, so that the colorimetric of photographing calibration, as in the represented embodiment of Figure 17.The scale of appointment can be for carrying out especially white balance.

In the time should carrying out the color evaluation being undertaken by observer, can the rotation disc having on its circumference corresponding to the color scale of desired tone is fixing onboard, as in the represented embodiment of Figure 18.Therefore user can extract different tones to evaluate close to that of region to be evaluated.

Amplifying device can be placed in before watch window, embodiment as represented in Figure 19.

In a special embodiment, before color filter can being placed in to light source and/or before watch window.These color filters can be for filtering specific wavelength, making light polarization or particularly indicating characteristic.

In a special embodiment, portion is placed on the grenade instrumentation of structurized light on area-of-interest in the enclosure, and described structurized light can be linear, grid or any pattern.The projection of structurized light allows to help user to evaluate the projection of institute's survey region, and if carried out the record of the projection of structurized light, and so can be for by means of the observed projection of computational algorithm reconstruct.

In a special embodiment, can place and measure by the light stream of watch window perception or the device of reflectance in inside.

For the ease of the location between the different time of the device on studied area-of-interest and reorientation, the module of projection light labelling can be fixed on the shell of device, as in the represented embodiment of Figure 20.Reorientation also can be by being fixed in another structure and the module that labelling is incident upon on skin realizes, thereby allow to place this device as in embodiment represented on Figure 21.

In a special embodiment, can the one or more sensors and the described plate that contact or do not measure contiguously the physical attribute of skin be carried out integrated to measure for example temperature or hydration.These sensors can be capacity type, resistance type or hot types.

The power supply of described device can be battery or set of cells, can by transformator or other power supplys for example the USB port of computer realize.

This device allows to break away from outside optical condition.

Claims (according to the modification of the 19th of treaty)

1. the optimization in definite human skin region illumination is to allow the method for its apparent condition of research, this skin area has raised areas, this illumination carrys out the device of self-contained one or more light source and near raised areas, produces shadow region, it is characterized in that comprising the following steps:

-according to the uniformity of luminosity, limit the second parameter P2,

The maximum of-searching cost function C,

The peaked method of finding cost function C is repetition, the first test starts to carry out from underlying parameter, by or based on visual method or based on representing, inhomogeneityly come self-metering designator to study the impact of each parameter on result as photodistributed interval type etc., then use by using the parameter of this device renewal and verification experimental verification to carry out new test, this allows to optimize illumination, and this series of steps is re-started until result is best.

2. according to the method for the optimization illumination in definite human skin region of claim 1, it is characterized in that, described cost function is restricted to the form of C=a*P1+b*P2, and wherein a and b are real number.

3. according to the method for the optimization illumination in definite human skin region of

claim

1 or 2, it is characterized in that, the maximum of finding cost function C comprises the step of wherein studying the variation of C according to the variation of at least one following parameters: the type of light source, light source with respect to the height (h) of skin, light source with respect to the distance (e) of skin and each light source the light angle (α) with respect to considered skin area.

4. the device in human skin region that throws light on, this skin area has raised areas, this device comprises one or more light source and near raised areas, produces shadow region, and this device has according to determined at least one the following feature of the method for any one in claims 1 to 3: light source with respect to the height (h) of skin, light source with respect to the distance (e) of skin and each light source the light angle (α) with respect to considered skin area.

5. according to the device of claim 4, it is characterized in that, at least one light source is point-like.

6. according to the device of claim 4 or 5, it is characterized in that comprising the window for observing.

7. according to the device of any one in claim 4 to 6, it is characterized in that comprising the camera chain of the structure that is fixed to this device.

8. according to the device of any one in claim 4 to 7, it is characterized in that this device is connected to permission photography is recorded to the also device of long-distance transmissions.

9. according to the device of any one in claim 4 to 8, it is characterized in that comprising and make this device on the minimized plate leaning against on skin of the impact of measured zone.

10. according to power, require 9 device, it is characterized in that, described plate comprise allow this device around be fixed to skin outer member automatic centring to central module.

11. according to the device of any one in claim 4 to 10, it is characterized in that comprising the projection parts of light that can emitting structural.

12. according to the device of any one in claim 4 to 11, it is characterized in that comprising the catoptrical measurement component of measurement.

13. according to the device of any one in claim 4 to 12, it is characterized in that the optical character projection parts that comprise auxiliary reorientation.

14. according to the device of any one in claim 4 to 13, it is characterized in that comprising one or more sensor of the physical attribute of measuring skin.

Claims

-according to the uniformity of luminosity, limit the second parameter P2,

The maximum of-searching cost function C.

3. according to the method for the optimization illumination in definite human skin region of claim 1 or 2, it is characterized in that, the maximum of finding cost function C comprises the step of wherein studying the variation of C according to the variation of at least one following parameters: the type of light source, light source with respect to the height (h) of skin, light source with respect to the distance (e) of skin and each light source the light angle (α) with respect to considered skin area.

4. the throw light on device in human skin region, it has according to determined at least one the following feature of the method for any one in claims 1 to 3: light source with respect to the height (h) of skin, light source with respect to the distance (e) of skin and each light source the light angle (α) with respect to considered skin area.

8. one kind is connected to and allows photography record the also device of the device of long-distance transmissions.

9. according to the device of any one in claim 4 to 7, it is characterized in that comprising and make this device on the minimized plate leaning against on skin of the impact of measured zone.

10. device according to Claim 8, is characterized in that, described plate comprise allow this device around be fixed to skin outer member automatic centring to central module.