CN1035100C - Medicine and preparing method thereof - Google Patents
Medicine and preparing method thereof Download PDFInfo
- Publication number
- CN1035100C CN1035100C CN 93110295 CN93110295A CN1035100C CN 1035100 C CN1035100 C CN 1035100C CN 93110295 CN93110295 CN 93110295 CN 93110295 A CN93110295 A CN 93110295A CN 1035100 C CN1035100 C CN 1035100C
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- medicine
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- cordyceps
- salviae miltiorrhizae
- radix
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Abstract
The present invention relates to a traditional Chinese medicine mainly used for treating renal glomerular disease and a preparation method thereof, which belongs to the technical field of medicines. The medicine is prepared from Chinese herbal medicines in China by the preparation method, and comprises components of the following proportion: 1 to 15g of aweto, 5 to 20g of membranous milkvetch root and 3 to 20g of red sage root, preferably 1 to 15g of aweto, 5 to 20g of membranous milkvetch root, 3 to 20g of red sage root and 3 to 20g of flos carthami. Large amount of clinical applications for years show that the present invention can increase the T cell-mediated immunity and erythrocyte immune functions, reduce urokinase proteins and increase serum albumins for patients with chronic nephritis, and can postpone the development of the states of illnesses for patients with renal failure at stage I to III.
Description
The invention belongs to field of pharmaceutical technology, is a kind of Chinese medicine that is mainly used in the treatment renal glomerular disease and preparation method thereof.
Kidney is basis of human body, and renal glomerular disease is very harmful to human body, and prevalence is higher in China's population.At present, in the renal glomerular disease to the medicine of chronic nephritis treatment, except that the prednisone effect better, still do not have any curative effect medicine preferably.But, take prednisone for a long time, easily bring many side effect to the patient, such as: secondary infection, obesity, Proteometabolism, carbohydrate metabolism and the unusual steady unrest of lipid metabolism or the like, the treatment of renal failure except that blood staticizes therapy and renal transplantation method, there is not Therapeutic Method preferably too.The medicine of some treatment renal failure, as: the curative effect of oral medicines such as Ketosteril all, to renal failure I～III phase patient owing to can not reduce blood urea nitrogen and blood flesh, liver, thereby can not delay the conditions of patients development.
The objective of the invention is, a kind of Chinese medicine is provided, be mainly used in the treatment renal glomerular disease, when making it without any side effects, curative effect is better.Can impel patient's serum albumin to raise after taking, cellular immunization strengthens, and erythrocyte immune strengthens, and reduces urine protein, reduces blood urea nitrogen, blood creatinine etc.
Medicine of the present invention all adopts China's Chinese herbal medicine formulated through preparation method of the present invention.Medicine of the present invention is the medicament with the feedstock production one-tenth of following weight ratio: Cordyceps 1-15g, Radix Astragali 5-20g
Radix Salviae Miltiorrhizae 3～20g, (prescription consumption of the present invention is adult's oral dose, described consumption is the powdery weight of being produced by medicament preparation method of the present invention), wherein the Radix Astragali can adopt Radix Codonopsis, Radix Pseudostellariae, Radix Ginseng Rubra, Radix Panacis Quinquefolii, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Fructus Jujubae and Radix Glycyrrhizae etc. substitute, Radix Salviae Miltiorrhizae can adopt Flos Carthami, Semen Persicae, Rhizoma Chuanxiong, Scolopendra, Herba Leonuri, Radix Curcumae, Radix Paeoniae Rubra, Herba Leonuri, Squama Manis, Olibanum, Rhizoma Curcumae Longae and Rhizoma Corydalis etc. substitute, because the function of these Chinese herbal medicine and the Radix Astragali and Radix Salviae Miltiorrhizae is close, so adopt described any alternative Radix Astragali or Radix Salviae Miltiorrhizae, all make medicine of the present invention still have certain curative effect.
Medicine of the present invention is the medicament with the feedstock production one-tenth of following weight ratio: Cordyceps 2-15g, the Radix Astragali 5～15g, Radix Salviae Miltiorrhizae 3～15g.The best amount ranges of drug formulation of the present invention is: Cordyceps 3～15g, the Radix Astragali 7～13g, Radix Salviae Miltiorrhizae 3～7g.Better amount ranges that the present invention got and best amount ranges are comprehensively to make according to therapeutic effect and production cost (patient's economic ability to take the burden).
Drug formulation of the present invention and amount ranges are: Cordyceps 1～15g, the Radix Astragali 5～20g, Radix Salviae Miltiorrhizae 3～20g, Flos Carthami 3～20g.The fill a prescription range of choice of better consumption of the present invention is: Cordyceps 2～15g, the Radix Astragali 5～15g, Radix Salviae Miltiorrhizae 3～15g, Flos Carthami 3～15g.The present invention's best consumption range of choice of filling a prescription is: Cordyceps 3～15g, the Radix Astragali 7～13g, Radix Salviae Miltiorrhizae 3～7g, Flos Carthami 3～7g.
The present invention is the medicament with the feedstock production one-tenth of following weight ratio: Cordyceps 1-15g, the Radix Astragali 5～20g, Radix Salviae Miltiorrhizae 3～20g, Flos Carthami 3～20g, Semen Ziziphi Spinosae (parched) 3～25g.The present invention is the medicament with the feedstock production one-tenth of following weight ratio: Cordyceps 2-15g, the Radix Astragali 5～15g, Radix Salviae Miltiorrhizae 3～15g, Flos Carthami 3～15g, Semen Ziziphi Spinosae (parched) 4～20g.The present invention is the medicament with the feedstock production one-tenth of following weight ratio: the Cordyceps 3-15g Radix Astragali 7～13g, Radix Salviae Miltiorrhizae 3～7g, Flos Carthami 3～7g, Semen Ziziphi Spinosae (parched) 5～10g.Medicine of the present invention is the medicament with the feedstock production one-tenth of following weight ratio: Cordyceps 1-15g, Radix Salviae Miltiorrhizae 3-20g, Flos Carthami 3～20g.Drug formulation of the present invention amount ranges preferably is: Cordyceps 1～15g, Radix Salviae Miltiorrhizae 3～15g, Flos Carthami 3～15g.
The preparation method of aforesaid medicine of the present invention is, powdery is made in the Cordyceps oven dry, with the medical herbs Radix Astragali and Radix Salviae Miltiorrhizae, and the perhaps Radix Astragali, Radix Salviae Miltiorrhizae, Flos Carthami.The perhaps Radix Astragali, Radix Salviae Miltiorrhizae, Flos Carthami Semen Ziziphi Spinosae (parched), perhaps Radix Salviae Miltiorrhizae and Flos Carthami, take advantage of 3 or 4 times as the Radix Astragali 5～20g according to drug formulation consumption of the present invention, get the medical herbs Radix Astragali 20～80g during preparation, after mixed back is even, put into sand tool or porcelain tool and soak 60～300 minutes decoctings twice, get its liquid, put into sand or porcelain tool, water is evaporated through twice of decocting, make powdery after active ingredient oven dry that will be remaining is taken out, with Cordyceps powdery mix homogeneously medicine of the present invention.
The preparation method of medicine of the present invention is: powdery is made in the Cordyceps oven dry, medical herbs such as the Radix Astragali, Radix Salviae Miltiorrhizae, Flos Carthami, Semen Ziziphi Spinosae (parched) are put into sand tool or porcelain tool respectively soaked after 60～300 minutes decocting twice, get its liquid, put into sand tool or porcelain tool, water is evaporated through twice of decocting, with remaining active ingredient oven dry, make powdery after the taking-up, then according to prescription of the present invention and consumption requirement, mix homogeneously, flavoring agent is made medicine of the present invention a little.
The purposes of medicine of the present invention is mainly used in the treatment renal glomerular disease, i.e. the patient of the chronic nephritis of various histological type (particularly IgA nephropathy) renal failure I～III phase.IgA nephropathy is not to still there being any medicine that has treatment to control so far in the world, and a large amount of clinical cases of medicine warp of the present invention and pathology, immunofluorescence are radiated, Electronic Speculum detects has fabulous curative effect to this disease.
Medicine of the present invention is checked through units concerned, contains 16 seed amino acids, and 14 kinds of trace element do not contain hormone composition (being not have hydrocortisone, estradiol, testosterone in the medicine).Medicine of the present invention, prove through a large amount of clinical practices for many years, to the chronic nephritis patient, can make it increase TT cellular immunization, erythrocyte immune, reduce urine protein, increase serum albumin, reduce blood ester (cholesterol, triglyceride), these clinical observation results are to adopt statistical procedures, P＜0.01,99 people's significant effective in the middle of promptly per 100 people.To renal failure I～III phase patient; Can delay PD, especially renal failure I～II phase patient curative effect is obvious especially, mainly is to make it increase serum albumin to the renal failure patient, strengthens cellular immunization, strengthens the erythrocyte immune system, reduces blood urea nitrogen and blood creatinine.These clinical cases adopt statistical procedures equally, P＜0.05～0.01.Medicine of the present invention is to the nephritis of simple hematuria for performance, and curative effect is also fine.
The present invention is with the medicament of the feedstock production one-tenth of following weight ratio, can produce with reference to following scheme.
1, Cordyceps 15g, Radix Astragali 5g, Radix Salviae Miltiorrhizae 5g.
2, Cordyceps 1g, Radix Astragali 20g, Radix Salviae Miltiorrhizae 10g.
3, Cordyceps 10g, Radix Astragali 10g, Radix Salviae Miltiorrhizae 20g.
4, Cordyceps 5g, Radix Ginseng Rubra 5g, Flos Carthami 20g.
5, Cordyceps 10g, Radix Astragali 20g, Radix Salviae Miltiorrhizae 3g.
6, Cordyceps 3g, Radix Astragali 15g, Radix Salviae Miltiorrhizae 7g, Flos Carthami 3g.
7, Cordyceps 2g, Radix Astragali 7g, Radix Salviae Miltiorrhizae 7g, Flos Carthami 7g, Semen Ziziphi Spinosae (parched) 5g.
8, Cordyceps 3g, Radix Codonopsis 13g, Semen Persicae 7g, Flos Carthami 8g, Semen Ziziphi Spinosae (parched) 20g.
9, Cordyceps 5g, Radix Salviae Miltiorrhizae 3g, Flos Carthami 3g.
10, Cordyceps 3g, Radix Salviae Miltiorrhizae 20g, Stigma Croci 15g.
11, Cordyceps 15g, Radix Salviae Miltiorrhizae 10g, Stigma Croci 20g.
12, Cordyceps 3g, Radix Astragali 13g, Flos Carthami 7g, Radix Salviae Miltiorrhizae 7g, Semen Ziziphi Spinosae (parched) 5g.
The present invention all adopts preparation method of the present invention to manufacture with the medicament of the feedstock production one-tenth of above-mentioned weight ratio.
Claims (2)
1, a kind of medicine for the treatment of renal glomerular disease is characterized in that it is the medicament that becomes with the feedstock production of following weight ratio: Cordyceps 1-15g, Radix Astragali 5-20g, Radix Salviae Miltiorrhizae 3-20, Flos Carthami 3-20g, Semen Ziziphi Spinosae (parched) 3-25g.
2, it is characterized in that according to the described a kind of Chinese patent medicine for the treatment of renal glomerular disease of claim 1 it is the medicament that becomes with the feedstock production of following anharmonic ratio: Cordyceps 3g, Radix Astragali 13g, Flos Carthami 7g, Radix Salviae Miltiorrhizae 7g, Semen Ziziphi Spinosae (parched) 5g.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93110295 CN1035100C (en) | 1993-03-06 | 1993-03-06 | Medicine and preparing method thereof |
| CN 94110465 CN1109772A (en) | 1993-03-06 | 1994-03-04 | Medicine and preparing process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93110295 CN1035100C (en) | 1993-03-06 | 1993-03-06 | Medicine and preparing method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1091968A CN1091968A (en) | 1994-09-14 |
| CN1035100C true CN1035100C (en) | 1997-06-11 |
Family
ID=4988174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93110295 Expired - Lifetime CN1035100C (en) | 1993-03-06 | 1993-03-06 | Medicine and preparing method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1035100C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1063065C (en) * | 1997-01-13 | 2001-03-14 | 吴荫福 | Decoction forgastritis |
| CN103585454B (en) * | 2013-12-02 | 2016-06-01 | 杭州国草生物科技有限公司 | A kind of anti-oxidant Cordyceps sinensis composition with strengthening immunity |
| CN103638136B (en) * | 2013-12-22 | 2015-09-16 | 翔宇药业股份有限公司 | Cordyceps QISHEN CAPSULE |
| CN104435671A (en) * | 2014-11-13 | 2015-03-25 | 成都华熹科技有限公司 | Cordyceps-sinensis-containing traditional Chinese medicine composition for enhancing immunity |
| CN108379338A (en) * | 2018-05-14 | 2018-08-10 | 刘俊廷 | It is a kind of to treat uremic Chinese medicine composition |
| CN112007089A (en) * | 2020-09-28 | 2020-12-01 | 梁栋才 | A Chinese medicinal oral liquid for treating nephritis |
-
1993
- 1993-03-06 CN CN 93110295 patent/CN1035100C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1091968A (en) | 1994-09-14 |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| CI01 | Correction of invention patent gazette |
Correction item: The patent application is deemed to be withdrawn Correct: delete False: A61K35/78 93110295.2 1994.09.14 Number: 47 Page: 184 Volume: 11 |
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| ERR | Gazette correction |
Free format text: CORRECT: DEEMED WITHDRAWAL OF APPLICATION FOR PATENT; FROM: A61K 35/78 93110295.2 94.9.14 TO: DELETION |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |
Expiration termination date: 20130306 Granted publication date: 19970611 |