CN103463274B - Medicine for treating psoriasis - Google Patents

Medicine for treating psoriasis Download PDF

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CN103463274B
CN103463274B CN201310323307.0A CN201310323307A CN103463274B CN 103463274 B CN103463274 B CN 103463274B CN 201310323307 A CN201310323307 A CN 201310323307A CN 103463274 B CN103463274 B CN 103463274B
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medicine
psoriasis
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seeing
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CN103463274A (en
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张丽敏
张云阁
张丽珍
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Abstract

The invention provides a medicine for treating psoriasis. The medicine comprises the following traditional Chinese medicines by weight: 1 to 7 parts of abietin, 1 to 5 parts of a willow branch, 2 to 9 parts of Sinapis alba, 1 to 5 parts of musk, 1 to 8 parts of cicada slough and 1 to 7 parts of peony root bark. The traditional Chinese medicines in the medicine can clear heat, remove toxins, clear and activate the channels and collaterals, relieve itching and engender flesh, enables skin tissue to be revitalized and allows lesion tissue to regain its normal physiological functions. The medicine is a drug of first choice for treatment of psoriasis.

Description

A kind of antipsoriatics thing
Technical field
The invention belongs to field of medicaments, be specifically related to a kind of antipsoriatics thing.
Background technology
Psoriasis is a kind of common chronic dermatosis, pimple, erythema that on skin, performance is differed in size, and surface coverage silvery white squama, and clear border is apt to occur in scalp, extremity and back.Doctor trained in Western medicine is called " psoriasis " (psoriasis) by psoriasis, if the drug main steroid hormone that western medical treatment psoriasis adopts, as triamcinolone and urea cream, clobetasol, clobetasol propionate frost, halcinonidedcorten preparation etc., at disease sites, apply these medicines, although psoriasis is had to certain curative effect, these drug side effectes are larger, life-time service can develop immunity to drugs, simultaneously larger to Health Impact.
The traditional Chinese medical science thinks, psoriasis pathogeny is because liver yin and yang imbalance causes, because liver belongs to wood, main QI and blood, has store blood and catharsis function, Tibetan blood pertaining to YIN wherein, catharsis belongs to sun, and when catharsis function is strong, liver-yang is contained, the excess of YANG is the deficiency of YIN, and men outnumbered women can cause air dry in human body, also can make skin surface dry, skin hydropenia part is nourished and is caused psoriasis to produce, from winter in psoriasis spring, easily recur or increase the weight of, and these symptoms of many alleviations summer and autumn can prove this theory.
In the time of conditioning liver yin and yang imbalance, also should separate blood poison, have the principle of Historical Data Data About " incessant pruritus, dominant wind making the body shaking are itched and come from wind, control wind and first control blood, and blood wind is from going out ", also answer dispelling wind to nourish blood, clearing heat and expelling damp.
Modern medicine utilizes the mode conditioning viscera of Chinese medicine for oral administration conventionally, nourishing YIN and benefiting blood, blood circulation promoting and blood stasis dispelling, so that equilibrium between yin and yang, and then eliminate psoriasis, men outnumbered women is because the moon of causing of the excess of YANG declines for liver, or the excess of YANG that declines and cause because cloudy, this is contradiction very when medication, so oral drugs whatsoever, its cure rate is very limited, and some patient takes a kind of medicine for the treatment of can play opposite effect.
Psoriasis, because liver yin and yang imbalance, blood poison are not understood and caused, is the outward manifestation of viscera disease, although penetrate into internal organs by liniment, also can effect a radical cure psoriasis, and different because of the selection of medicine, its therapeutic effect exists very large gap.Name as disclosed in No. 10361783A, Chinese patent is called " a kind of treat psoriasic application compress " and proposes to utilize Herba speranskiae tuberculatae and Radix Codonopsis after soaking in Chinese liquor, to smear affected part, to treat psoriasic example, although this kind of application compress cost is relatively low, nontoxic, have no side effect, but the content of recording from doctor's treasured book, Herba speranskiae tuberculatae expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation, pain relieving, for rheumatic arthralgia, muscles and bones contracture, the disturbance of lower legs due to pathogenic cold and dampness, the diseases such as skin ulcer tinea toxic swelling.Radix Codonopsis tonification, invigorating the spleen and replenishing QI, for deficiency of QI in middle-JIAO, deficiency of the spleen and lung, the diseases such as extremity asthenia.As can be seen here, can these two kinds of drug regimens reach balance liver negative and positive, thoroughly effects a radical cure psoriasis, needs further to inquire into.
Summary of the invention
The object of the present invention is to provide a kind of antipsoriatics thing.
The invention provides a kind of antipsoriatics thing, this medicine is comprised of the Chinese medicine of following parts by weight: Colophonium fat 1-7 part, Ramulus Salicis Babylonicae 1-5 part, Semen Sinapis Albae 2-9 part, Moschus 1-5 part, Periostracum Cicadae 1-8 part, Cortex Moutan 1-7 part.Be preferably Colophonium fat 1-5 part, Ramulus Salicis Babylonicae 1-4 part, Semen Sinapis Albae 2-7 part, Moschus 1-4 part, Periostracum Cicadae 2-6 part, Cortex Moutan 1-5 part.Most preferably be Colophonium fat 2-4 part, Ramulus Salicis Babylonicae 2-3 part, Semen Sinapis Albae 2-5 part, Moschus 1-2 part, Periostracum Cicadae 2-4 part, Cortex Moutan 1-3 part.
Colophonium fat: surgical medicine, nourishing YIN and invigorating YANG, dampness is dispeled the wind, granulation promoting pain relieving, pruritus herpes, eliminating carbuncle subcutaneous ulcer, dislikes rash, treatment scabies, rubella, skin pruritus.
Ramulus Salicis Babylonicae: sweet salty, rash, removing toxic substances, antiinflammatory, can also treat skin rubella, whole body pruritus, so that interior strongly fragrant of sore does not go out.This Ramulus Salicis Babylonicae is the branch of willow.
Semen Sinapis Albae: pungent loose promoting the circulation of QI, warming lung for dispelling cold, removing obstruction in the collateral to relieve pain, the external application skin ulcer that disappears, softening mass in the abdomen, congestion.
Moschus: have the refreshment of having one's ideas straightened out, the function of promoting blood circulation to remove obstruction in the collateral, records in < < Compendium of Materia Medica > >, logical all keys, open meridians, thoroughly flesh bone, alcoholic intoxication, the melon and fruit food stagnation that disappears, controls apoplexy, middle gas, attacked by pestiferous factors, Moschus is walked to alter, can lead to the unfavorable of all keys, open the heap soil or fertilizer over and around the roots of meridians and hold back, if all diseases of all blood of all gas of all wind, with leading to it for guiding with what open, but can not cross also.
Periostracum Cicadae: relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, loose wind heat extraction, rash is antipruritic, and improving acuity of vision and removing nebula is controlled skin wind heat, the diseases such as tetanus and furuncle toxic swelling skin ulcer.
Above-mentioned a few taste medicine all has heat-clearing and toxic substances removing, dredge the meridian passage, and antipruritic effect and promoting granulation, makes skin histology again shine granulation promoting, makes pathological tissues recover normal physiological function.
In medicine of the present invention, also comprise Cortex Moutan, Cortex Moutan GUIXIN, liver, kidney channel, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, according to recording in < < Compendium of Materia Medica > >, Cortex Moutan is controlled the blood fire second of the three ten-day periods of the hot season, heat clearing away and restlessness relieving, motherland's traditional medicine is thought, human body feelings will dysphoria with smothery sensation, interior-heat causes toxin to block up, to such an extent as to cause skin generation pathological changes, so the present invention has used the medicine of Cortex Moutan as " removing heat from blood ", dispel heat in blood, in most activating blood and removing stasis drugs, the blood circulation often causing due to the medicine effect of invigorating blood circulation accelerates to make human body depletion fire syndrome going up, but the medicine that can't there is no blood circulation promoting and blood stasis dispelling in compatibility of drugs, so can keep blood circulation promoting and blood stasis dispelling can not allow again patient become main route of administration because depletion fire syndrome going up causes aggravation with regard to making, the distinctive removing heat from blood effect of Cortex Moutan has just in time reached the effect of " forming a connecting link ", asthenic fire is fallen, heat clearing away and restlessness relieving, made up the strong of blood circulation promoting medicine, make human body more acceptant, so it is unobstructed to adopt the mode of blood circulation promoting and blood stasis dispelling that energy and blood of human body is circulated, its pathological tissues is regained vitality, and then make liver equilibrium between yin and yang.
Accompanying drawing explanation
The psoriasic photo of Fig. 1 embodiment 1;
Fig. 2 embodiment 1 curing psoriasis photo of 15 days;
Fig. 3 embodiment 1 curing psoriasis photo of 1 month;
Fig. 4 embodiment 1 curing psoriasis photo of 2 months;
The psoriasic photo of Fig. 5 embodiment 2;
Fig. 6 embodiment 2 curing psoriasis photo of 30 days;
Fig. 7 embodiment 2 curing psoriasis photo of 45 days;
The psoriasic photo of Fig. 8 embodiment 3;
Fig. 9 embodiment 3 curing psoriasis photo of 1 month;
Figure 10 embodiment 3 curing psoriasis photo of 2 months;
The psoriasic photo of Figure 11 embodiment 4;
Figure 12 embodiment 4 curing psoriasis photo of 10 days;
Figure 13 embodiment 4 curing psoriasis photo of 1 month;
The psoriasic photo of Figure 14 embodiment 5;
The photo of 1 first quarter moon of Figure 15 embodiment 5 curing psoriasis;
Figure 16 embodiment 5 curing psoriasis photo of 2 months;
The psoriasic photo of Figure 17 embodiment 6;
Figure 18 embodiment 6 curing psoriasis photo of 1 month;
Figure 19 embodiment 6 curing psoriasis photo of 2 months.
The specific embodiment
The following examples will be further described the present invention, but not thereby limiting the invention.
The preparation process of medicine of the present invention:
Dosage form I: get Colophonium fat 20g, Ramulus Salicis Babylonicae 20g, Semen Sinapis Albae 50g, Moschus 10g, Periostracum Cicadae 20g, Cortex Moutan 20g, pulverize, add 1000 liters, water, heating extraction, medicinal liquid simmer down to 50-100 milliliter after extracting, is medicinal liquid of the present invention.
Dosage form II: get Colophonium fat 30g, Ramulus Salicis Babylonicae 30g, Semen Sinapis Albae 30g, Moschus 20g, Periostracum Cicadae 30g, Cortex Moutan 20g, pulverize, add 1000 liters, water, heating extraction, medicinal liquid simmer down to 50-100 milliliter after extracting, is medicinal liquid of the present invention.
Dosage form III: get Colophonium fat 40g, Ramulus Salicis Babylonicae 20g, Semen Sinapis Albae 40g, Moschus 20g, Periostracum Cicadae 40g, Cortex Moutan 30g, pulverize, add 1000 liters, water, heating extraction, medicinal liquid simmer down to 50-100 milliliter after extracting, is medicinal liquid of the present invention.
Antipsoriatics thing proposed by the invention is once to 160 routine patient treatment mistakes, male's 98 examples wherein, women's 62 examples, minimum 23 years old of age, the oldest 78 years old, course of disease phase 1-10, after using Chinese medicine composition provided by the invention, 1-2 month obviously takes effect, in 160 routine patients, clinical cure 90 examples, effective 30 examples, effective 30 examples, invalid 10 examples, total effective rate 93.75%, wherein takes effect the fastest 15 days, the slowest 70 days, and stop observation post administration to curing case, 6 months there are no recidivist.
Embodiment 1
Chen, man, 47 years old, Benxi, Liaoning Province North Platform people, nineteen ninety is because of living environment humidity, there is coin size erythema in calf, itch, companion's desquamation, general whole body within 1 year, repeatedly used Chinese medicine, Western medicine, be better than once, do not have 3 months and continue to recur to whole body, do not fully recover always, in scalp, on arm, two legs, shirtfront, the whole desquamations of back, very itch unbearably, because the course of disease time is long, with prodrug complex, major injury hepatic and renal function, finger starts distortion, crooked, stretch not straight, hands, knee has serious hyperosteogeny, hold incessantly pen, sometimes hold is reluctantly also hurt like hell, foot waihuaiji place has large one of palm to rot, do not like healing, limp on foot, very painful.After being introduced, within 2009, December comes here on 20th, is diagnosed as " psoriasis " (seeing Fig. 1).
Within 2009, December starts external application medicine of the present invention on the 22nd, further consultation afterwards in 15 days, and the position of medication is desquamation no longer, exposes scarlet soft textive, and the symptom of itching alleviates (seeing Fig. 2); Continue medication, the whole body phenomenon of not peeling after 1 month, red meat is local starts slowly to become black seal (seeing Fig. 3); Continue medication after 2 months, whole body returns to one's perfect health (seeing Fig. 4), and hands can hold a pen, and not bitterly, hyperosteogeny transference cure, foot external malleolus rotten place is fully recovered, walks dexterous, can morning exercises and energetic.
Embodiment 2
Zhang, man, 75 years old, the new retired old soldier in home one in the north, Benxi, Liaoning Province, 2008 start, and mottled red point appears in back, lumbar vertebra place, itches, scratch every day with hands, area is increasing, finally forms sclerderm, and there is squama top, with crossing, many medicines are all ineffective, come here to be diagnosed as " psoriasis " (seeing Fig. 5).
Within 2010, JIUYUE starts external application medicine of the present invention on the 10th, sooner or later respectively once, medication after 3 days squama disappear, affected part starts rubescent, unlike itching so in the past, continue medicine and amass and start to dwindle below for 30 days, sclerderm partly starts to become soft (seeing Fig. 6), medication recovery from illness (seeing Fig. 7) afterwards in 45 days.
Embodiment 3
Wang, female, 22 years old, people from Lingyuan City, Liaoning Province, within 2007, autumn femoribus internus goes out cash shape erythema, very itch, then decortication, with western medicine, after 1 month, the diffusion of whole body large area, used Chinese medicine afterwards instead, after medication, whole body swelling, is finally forced to drug withdrawal, sometimes has fever phenomenon.Here over 2008, is diagnosed as " psoriasis " (seeing Fig. 8).
Start external application medicine of the present invention in March, 2008, and after 1 month, swelling phenomenon disappears completely, consider obscission without silver morning, and the symptom of very itching starts to alleviate (seeing Fig. 9), continues after 2 first quarter moons of medication, have the place of silver bits all to disappear, skin becomes smooth (seeing Figure 10).
Embodiment 4
Ma, female, 43 years old, people from Dandong City, Liaoning Province, 2011 there is erythema in arm crook, itch, and scratch rear erythema and become large, all, large area is peeled for last whole arm, thigh, shirtfront, back, scalp.Take after the medicine of hospital, not only do not get better and turn, diffusion on the contrary, whole body starts redness, severe pain.Come after being introduced here, be diagnosed as " psoriasis " (seeing Figure 11).
Within 2011, JIUYUE starts external application medicine of the present invention on 22nd, and within the 3rd day, pain symptom alleviates, and inflammation disappears; Continue medication after 10 days whole body start sudden and violent skin, pain symptom disappears (seeing Figure 12) completely, rehabilitation after 1 month (seeing Figure 13).
Embodiment 5
Ma, man, 22 years old, Benxi, Liaoning Province workman, once unexpected, boiled water irons head-on bone place, scalded part and start to occur small red dot after scalding healing, itches, and then scratches, and scratches heavier and heavier, finally form sclerderm, used " PIKANGWANG ", " PIYANPING ", antipruritic effect is bad, within 3 years, does not also get better and turns.Come after being introduced here, be diagnosed as " psoriasis " (seeing Figure 14).
On August 12nd, 2012 starts external application medicine of the present invention, after 3 days, has not substantially itched; Continue 1 first quarter moon of medication, lesions position starts to dwindle gradually (seeing Figure 15); Continuing medication after 3 months, disappears in sclerderm position, and it is soft that lesions position all becomes, recovery from illness (seeing Figure 16).
Embodiment 6
Zhao, man, 42 years old, Benxi, Liaoning Province individual operator, this patient is in twenties arm crook, knee, just have " psoriasis " that nail cover is large, start afterwards the speckle that coin size appears in large area with it, last shank is more serious, coming here, is " psoriasis " (seeing Figure 17) after diagnosing.
On May 6th, 2013 starts external application medicine of the present invention, and after medication, there is a burning sensation in skin affected part, within 3 days, disappears afterwards, and skin surface squama starts to come off; Continue medication after 1 month, skin start to become smooth (seeing Figure 18); Continuation medication skin healing (seeing Figure 19) after 2 months.

Claims (3)

1. an antipsoriatics thing, is characterized in that: this medicine is made by the Chinese medicine of following parts by weight:
Colophonium fat 1-7 part, Ramulus Salicis Babylonicae 1-5 part, Semen Sinapis Albae 2-9 part, Moschus 1-5 part, Periostracum Cicadae 1-8 part, Cortex Moutan 1-7 part.
2. according to antipsoriatics thing described in claim 1, it is characterized in that: this medicine is made by the Chinese medicine of following parts by weight:
Colophonium fat 1-5 part, Ramulus Salicis Babylonicae 1-4 part, Semen Sinapis Albae 2-7 part, Moschus 1-4 part, Periostracum Cicadae 2-6 part, Cortex Moutan 1-5 part.
3. according to antipsoriatics thing described in claim 1, it is characterized in that: this medicine is made by the Chinese medicine of following parts by weight:
Colophonium fat 2-4 part, Ramulus Salicis Babylonicae 2-3 part, Semen Sinapis Albae 2-5 part, Moschus 1-2 part, Periostracum Cicadae 2-4 part, Cortex Moutan 1-3 part.
CN201310323307.0A 2013-07-29 2013-07-29 Medicine for treating psoriasis Expired - Fee Related CN103463274B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1163119A (en) * 1996-04-24 1997-10-29 卓万林 Chinese drug for curing psoriasis
CN102240336A (en) * 2011-07-05 2011-11-16 张丽敏 Chinese medicinal composition for treating psoriasis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1163119A (en) * 1996-04-24 1997-10-29 卓万林 Chinese drug for curing psoriasis
CN102240336A (en) * 2011-07-05 2011-11-16 张丽敏 Chinese medicinal composition for treating psoriasis

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