CN103453930B - For multiple testing integrity of small-area peg-top type hydrophobic air filters devices - Google Patents

For multiple testing integrity of small-area peg-top type hydrophobic air filters devices Download PDF

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Publication number
CN103453930B
CN103453930B CN201310331149.3A CN201310331149A CN103453930B CN 103453930 B CN103453930 B CN 103453930B CN 201310331149 A CN201310331149 A CN 201310331149A CN 103453930 B CN103453930 B CN 103453930B
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way pipe
hydrophobic air
type hydrophobic
interface
joint
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CN103453930A (en
Inventor
王亚军
张雪梅
李晓波
赵大鹏
顾建阳
张赐强
吴业红
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Changchun Institute of Biological Products
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Changchun Institute of Biological Products
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Abstract

The invention discloses a kind of for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, describedly comprise a serum bottle for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, a peristaltic pump, a silicone tube, a Pressure gauge, at least one three-way pipe, at least one valve and at least four joints, not only can carry out integrity test to multiple small size gyroscope type hydrophobic air filters simultaneously, can also utilize this covering device to carry out easy clean to multiple small size gyroscope type hydrophobic air filters, and this device wide adaptability, cost is lower, easy and simple to handle, more can save human resources for enterprise simultaneously.

Description

For multiple testing integrity of small-area peg-top type hydrophobic air filters devices
Technical field
The present invention relates to a kind of field of tester, when relating in particular to a kind of pharmaceutical industry and use for the device of multiple testing integrity of small-area peg-top type hydrophobic air filters.
Background technology
At present, small size hydrophobicity gyroscope type air filter is more and more used to pharmaceutical industry, of many uses because of it, especially can be used as the filtration of respirator and four gas of bioreactor, also can be used as the respirator of sterile chamber, it plays conclusive effect to ensureing the internal and external pressure balance of sterile chamber tool and the aseptic of system thereof, 2010 editions GMP guides clearly specify, the gas filtering contacts with final sterile product or relevant device significant surfaces, need to reach the strictest requirement of holding back. As, the compressed air of aseptic filler filters, the breather filter of aseptic former liquid storage tank, and the vacuum of freeze-drier or autoclave is abolished filter. Pneumatic filter for this type of application should be tested by liquid microbe challenge, and its physical integrity detects and need to be associated with liquid microbe challenge experiment. In situation about contacting with final sterile product as a kind of gas of the consumptive material with certain service life, particularly its filtration, must before and after each use, all carry out integrity test to it. The current air filter for larger filter area, user can detect with commercially available integrity detection instrument, but be not suitable for the gyroscope type air filter of small size, though some user can rule of thumb carry out manual test, but cannot ensure the accuracy of test, more cannot test fast and easy clean a large amount of filters simultaneously. Therefore, prior art needs further improve and develop.
Summary of the invention
In view of above-mentioned the deficiencies in the prior art, the object of the present invention is to provide a kind of for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, solved can be not the technical problem to testing integrity of small-area peg-top type hydrophobic air filters by hand, more solve the technical problem to multiple testing integrity of small-area peg-top type hydrophobic air filters simultaneously, this kind of method can improve detection efficiency, cost-saving and human resources.
Technical scheme of the present invention is as follows:
A kind of for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, wherein, describedly comprise a serum bottle for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, a peristaltic pump, a silicone tube, a Pressure gauge, at least one three-way pipe, at least one valve and at least four joints, wherein, described serum bottle is connected with described silicone tube entrance point, described peristaltic pump is arranged at described silicone tube stage casing, the described silicone tube port of export is connected with the first three-way pipe first interface by described joint, first three-way pipe the second interface is connected with the first valve, described valve connects described small size gyroscope type hydrophobic air filter by described joint, the first three-way pipe the 3rd interface is connected by joint with second three-way pipe first interface, second three-way pipe the second interface is connected with the second valve, second three-way pipe the 3rd interface can remove to connect the 3rd three-way pipe first interface in turn, the 3rd interface of last three-way pipe being connected to can be connected with described Pressure gauge by joint.
Described for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, wherein, described serum bottle is 5L, and described peristaltic pump and gaging pressure are suitable, and described peristaltic pump is to be that 3.1-6.4mm silicone tube is suitable with internal diameter.
Described for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, wherein, described Pressure gauge, described joint, described three-way pipe, and described valve is chuck mode syndeton.
One provided by the invention is for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, not only can carry out integrity test to multiple small size gyroscope type hydrophobic air filters simultaneously, can also utilize this covering device to carry out easy clean to multiple small size gyroscope type hydrophobic air filters, and this device wide adaptability, cost is lower, easy and simple to handle, more can save human resources for enterprise simultaneously.
Brief description of the drawings
Fig. 1 is the structural representation for multiple testing integrity of small-area peg-top type hydrophobic air filters devices in the present invention.
Detailed description of the invention
The invention provides a kind ofly for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, for making object of the present invention, technical scheme and effect clearer, clear and definite, below the present invention is described in more detail. Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
The invention provides a kind of for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, as shown in Figure 1, a kind of for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, comprise a serum bottle 101, silicone tube 102 and a peristaltic pump 103, described serum bottle 101 is 5L, described serum bottle 101 is that described peristaltic pump 103 is suitable with the pressure of measuring, described peristaltic pump 103 is suitable with described silicone tube 102, and the internal diameter of described silicone tube 102 is 3.1-6.4mm. the present invention also comprises a Pressure gauge 107 for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, at least one three-way pipe 108, at least one valve 105 and at least four joints 104, and small size gyroscope type hydrophobic air filter 106, wherein, described serum bottle 101 is connected with described silicone tube 102 entrance points, described peristaltic pump 103 is arranged at described silicone tube 102 stage casings, described silicone tube 102 ports of export are connected with the first three-way pipe 108 first interfaces by described joint 104, the first three-way pipe 108 second interfaces are connected with the first valve 105, described valve 105 connects described small size gyroscope type hydrophobic air filter 106 by described joint 104, the first three-way pipe 108 the 3rd interface is connected by joint 104 with second three-way pipe 108 first interface, second three-way pipe 108 second interface is connected with the second valve 105, second three-way pipe 108 the 3rd interface can remove to connect the 3rd three-way pipe 108 first interfaces in turn, the 3rd interface of last three-way pipe 108 being connected to can be connected with described Pressure gauge 107 by joint 104. wherein, described Pressure gauge 107, described joint 104, described three-way pipe 108, and described valve 105 is chuck mode syndeton.
The present invention connects closely for the each inter-module of multiple testing integrity of small-area peg-top type hydrophobic air filters devices, form a closed system, in integrity test process, adopt the water corresponding with described air filter 106 apertures to immerse, make pressure keep quantitative data, these data can be used as judgment basis, ensure the reliability of test result. Simultaneously the present invention also can be disposable carry out integrity detection to one or more small size gyroscope type hydrophobic air filters by simple autonomous assembling simultaneously and obtain and carry out easy clean simultaneously, again in test process if there is pressure drop or can not pressurize, only need find out the underproof gyro filter of integrality, close its corresponding valve and can continue other filters to test, the port of export that the underproof gyro filter of integrality takes the form of this gyro filter has water mark. This device is simple to operate, and adaptability is relatively wider, data are accurate, also can be enterprise simultaneously and saves manpower and cost.
Should be understood that, application of the present invention is not limited to above-mentioned giving an example, and for those of ordinary skills, can be improved according to the above description or convert, and all these improvement and conversion all should belong to the protection domain of claims of the present invention.

Claims (1)

1. for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, it is characterized in that, describedly comprise a serum bottle for multiple testing integrity of small-area peg-top type hydrophobic air filters devices, a peristaltic pump, a silicone tube, a Pressure gauge, multiple three-way pipes, multiple valves and multiple joint, wherein, described serum bottle is connected with the entrance point of described silicone tube, described peristaltic pump is arranged at the stage casing of described silicone tube, the port of export of described silicone tube is connected with the first three-way pipe first interface by described joint, first three-way pipe the second interface is connected with the first valve, described the first valve connects described small size gyroscope type hydrophobic air filter by described joint, the first three-way pipe the 3rd interface is connected by joint with second three-way pipe first interface, second three-way pipe the second interface is connected with the second valve, described second valve door connects described small size gyroscope type hydrophobic air filter by described joint, second three-way pipe the 3rd interface can remove to connect the 3rd three-way pipe first interface in turn, the 3rd interface of last three-way pipe being connected to can be connected with described Pressure gauge by joint,
Described Pressure gauge, described joint, described three-way pipe, and described valve is chuck mode syndeton;
Described serum bottle is 5L, and described peristaltic pump and gaging pressure are suitable, and described peristaltic pump is to be that 3.1-6.4mm silicone tube is suitable with internal diameter;
Serum bottle described in described testing arrangement, peristaltic pump, silicone tube, Pressure gauge, three-way pipe, valve and joint connect closely, form a closed system;
Multiple small size gyroscope type hydrophobic air filters carry out in the test process again after integrity detection, if there is pressure drop or can not pressurize, only need finding out the underproof small size gyroscope type of integrality hydrophobic air filter and cutting out its corresponding valve; When small size gyroscope type hydrophobic air filter is integrality when defective, the port of export of described small size gyroscope type hydrophobic air filter has water mark.
CN201310331149.3A 2013-08-01 2013-08-01 For multiple testing integrity of small-area peg-top type hydrophobic air filters devices Active CN103453930B (en)

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CN108332804B (en) * 2018-04-19 2024-01-23 中国科学院海洋研究所 Multi-parameter continuous observation system for navigation type ocean surface layer
CN109580126A (en) * 2019-01-18 2019-04-05 楚天科技股份有限公司 A kind of integrity detection system and method for freeze dryer filter
CN110375970A (en) * 2019-07-01 2019-10-25 浙江泰林分析仪器有限公司 A kind of full-automatic filter integrality multimachine test macro and method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101762561A (en) * 2009-11-10 2010-06-30 浙江天元生物药业股份有限公司 Method for on-line detecting integrity of ultrafiltration membrane by using ultraviolet monitoring method
CN201643862U (en) * 2010-04-20 2010-11-24 新乡平原航空技术工程有限公司 Detection device for testing integrity of filter element structure
CN201719931U (en) * 2010-06-30 2011-01-26 辽宁成大生物股份有限公司 Device for testing integrity of small-area peg-top type hydrophobic air filters
CN102229888A (en) * 2011-06-08 2011-11-02 南京大学医学院附属鼓楼医院 Feedback-type pneumatic-control pressure stress cell culture device
CN103090912A (en) * 2013-02-22 2013-05-08 昆山鸿福泰环保科技有限公司 Filter element detecting device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101762561A (en) * 2009-11-10 2010-06-30 浙江天元生物药业股份有限公司 Method for on-line detecting integrity of ultrafiltration membrane by using ultraviolet monitoring method
CN201643862U (en) * 2010-04-20 2010-11-24 新乡平原航空技术工程有限公司 Detection device for testing integrity of filter element structure
CN201719931U (en) * 2010-06-30 2011-01-26 辽宁成大生物股份有限公司 Device for testing integrity of small-area peg-top type hydrophobic air filters
CN102229888A (en) * 2011-06-08 2011-11-02 南京大学医学院附属鼓楼医院 Feedback-type pneumatic-control pressure stress cell culture device
CN103090912A (en) * 2013-02-22 2013-05-08 昆山鸿福泰环保科技有限公司 Filter element detecting device

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