CN103439432A - Dilution-free linear curve chromatograph and linear curve measuring method - Google Patents
Dilution-free linear curve chromatograph and linear curve measuring method Download PDFInfo
- Publication number
- CN103439432A CN103439432A CN2013104129854A CN201310412985A CN103439432A CN 103439432 A CN103439432 A CN 103439432A CN 2013104129854 A CN2013104129854 A CN 2013104129854A CN 201310412985 A CN201310412985 A CN 201310412985A CN 103439432 A CN103439432 A CN 103439432A
- Authority
- CN
- China
- Prior art keywords
- connecting hole
- communicated
- groove
- stator
- chromatograph
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Landscapes
- Multiple-Way Valves (AREA)
Abstract
The invention provides a dilution-free linear curve chromatograph and a linear curve measuring method. The dilution-free linear curve chromatograph comprises two separating columns, two pumps, a plurality of quantitative tubes, a twelve-way changeover valve and two selector valves for selecting different quantitative tubes to be communicated with the twelve-way changeover valve, wherein the separating columns, pumps and selector valves are respectively connected with the twelve-way changeover valve; and each selector valve is connected with a plurality of quantitative tubes. The selector valves are utilized to select different quantitative tubes to participate in detection; the quantitative tubes have different volumes, so that the different quantitative tubes can be utilized to change the number of substances entering the separating columns so as to obtain solutions with different concentrations; and in the measuring process, the operating personnel do not need to prepare solutions with different concentrations to perform measurement, thereby effectively preventing the container and artificial errors from influencing the accuracy of the linear curve, implementing the process of free of artificially diluting the solution, and enhancing the measurement accuracy of the dilution-free linear curve chromatograph.
Description
Technical field
The present invention relates to the Studies by Chromatography electricity testing device, relate in particular to a kind of chromatograph and linearity curve measuring method that linearity curve is made in dilution of exempting from.
Background technology
Chromatograph application chromatography is carried out the instrument of qualitative and quantitative analysis to material.As depicted in figs. 1 and 2, chromatograph of the prior art generally includes workstation 101, detecting device 102, detection cell 103, separating column 104, quantity tube 105 and 12 direction changeover valves 106, the two ends of quantity tube 105 are connected on two ports of 12 direction changeover valves 106, outside injector 108 is connected to 12 direction changeover valves 106, and leacheate container 107 also is connected on 12 direction changeover valves 106 by pump 1071.When needs are analyzed, at first, as shown in Figure 1, injector 108 is injected into solution to be analyzed in quantity tube 105 by 12 direction changeover valves 106, and too much solution enters into waste liquid barrel 109; After filling with solution to be analyzed in quantity tube 105, as shown in Figure 2,12 direction changeover valve 106 switching states, the leacheate that pump 1071 is carried enters into quantity tube 105 and the solution to be analyzed of quantity tube 105 is delivered to separating column 104, then analyzes the parameters such as appearance time, peak height and peak area of solution under this CONCENTRATION STATE through detection cell 103, detecting device 102 and workstation 101.When doing the stratographic analysis linearity curve, usually need to measure the parameter value of a plurality of concentration point to obtain linearity curve, and, because the volume V of quantity tube 105 is certain, must remove to change the quantity n that enters into separating column 104 materials, i.e. n=C*V by changing material concentration C.But, the linearity curve concentration point choose the precision General Requirements at several ppb(μ g/L) to tens ppm(mg/L) and between and select at least 5 concentration point, and in the drying of material and weigh, container scale and the error of material, the error of manual operation will affect the precision of linearly dependent coefficient, cause the reduction of chromatograph measuring accuracy; And, for cleaning repeatedly and the drying of container, accurately prepare the concentration solution of the required a plurality of concentration point of linearity curve, also increased greatly operating personnel's workload; In addition, when needs are tested zwitterion simultaneously, need to adopt two ion chromatographs to be measured, use cost is high, floor area is large, and the user uses inconvenience.
Summary of the invention
Technical matters to be solved by this invention is: a kind of chromatograph and linearity curve measuring method that linearity curve is made in dilution of exempting from is provided, solve chromatograph in prior art and be affected by human factors the defect that causes measuring accuracy to reduce, realize improving chromatographic measuring accuracy, reduce operating personnel's workload, be user-friendly to operation.
Technical scheme provided by the invention is, a kind ofly exempt from dilution and make the chromatograph of linearity curve, comprise two separating columns, two pumps, many quantity tubes, 12 direction changeover valves and two selector valves for selecting different described quantity tubes to be communicated with described 12 direction changeover valves, described separating column, described pump and described selector valve are connected with described 12 direction changeover valves respectively, and each described selector valve is connected with many described quantity tubes.
Further, described selector valve comprises stator and rotor, and the center of described stator is provided with the first connecting hole, and described stator Shang Raoqi center is provided with a plurality of the second connecting holes, also is provided with the 3rd connecting hole on described stator; The center of described rotor is provided with the first groove, described rotor Rao Qi center is provided with arc-shaped slot, the second groove and the 3rd groove, described the second groove is communicated with described the first groove and forms the first groove by the first link slot arranged on described rotor, and described the 3rd groove is communicated with described arc-shaped slot and forms the second groove by the second link slot arranged on described rotor; Described rotor is attached on described stator, and described the first groove is communicated with described the first connecting hole, and described the second groove and described the 3rd groove are communicated with corresponding described the second connecting hole, and described arc-shaped slot is communicated with described the 3rd connecting hole; Many described quantity tubes are connected between two corresponding described the second connecting holes, and described the first connecting hole is connected with described 12 direction changeover valves with described the 3rd connecting hole.
Further, be provided with the auxiliary circle deep-slotted chip breaker be communicated with described the 3rd connecting hole on described stator, the radius of described auxiliary circle deep-slotted chip breaker is identical with the radius of described arc-shaped slot, and described arc-shaped slot is communicated with described the 3rd connecting hole by described auxiliary circle deep-slotted chip breaker.
Further, also be fixedly connected with valve head on described stator, the center of described valve head is provided with the first external tapping, described valve head Shang Raoqi center is provided with a plurality of the second external tappings, also be provided with the 3rd external tapping on described valve head, described the first external tapping is communicated with described the first connecting hole, described the second external tapping is communicated with corresponding described the second connecting hole, described the 3rd external tapping is communicated with corresponding described the 3rd connecting hole, a plurality of described the second external tappings are the divergent shape setting or a plurality of described the second external tapping is distributed on the circumferential side wall of described valve head along inside surface to the outside surface direction of described valve head.
Further, described selector valve comprises stator and rotor, and described stator Shang Raoqi center is provided with two the first connecting holes and several second connecting holes; Described rotor Rao Qi center is provided with the arc-shaped slot corresponding with described the first connecting hole, also is provided with the groove corresponding with described arc-shaped slot and link slot on described rotor, and described groove is communicated with described arc-shaped slot and forms groove structure by described link slot; Described rotor is attached on described stator, and described arc-shaped slot is communicated with corresponding described the first connecting hole, and described groove is communicated with corresponding described the second connecting hole; Many described quantity tubes are connected between two corresponding described the second connecting holes, and two described the first connecting holes are connected with described 12 direction changeover valves.
Further, be provided with the auxiliary circle deep-slotted chip breaker corresponding with described the first connecting hole on described stator, described auxiliary circle deep-slotted chip breaker is communicated with described the first connecting hole, the radius of described auxiliary circle deep-slotted chip breaker is identical with the radius of corresponding described arc-shaped slot, and described arc-shaped slot is communicated with described the first connecting hole by described auxiliary circle deep-slotted chip breaker.
Further, also be fixedly connected with valve head on described stator, be provided with first external tapping corresponding with described the first connecting hole on described valve head, described valve head Shang Raoqi center is provided with the second external tapping that a plurality of and described the second connecting hole is corresponding, described the first external tapping is communicated with corresponding described the first connecting hole, described the second external tapping is communicated with corresponding described the second connecting hole, and a plurality of described the second external tappings are the divergent shape setting or a plurality of described the second external tapping is distributed on the circumferential side wall of described valve head along inside surface to the outside surface direction of described valve head.
Further, the center of circle of described the second connecting hole is distributed in and take on the circular trace that the center of described stator is the center of circle.
Further, on described stator, be provided with boss structure, described rotor is attached on the surface of described boss structure.
The present invention also provides a kind of linearity curve measuring method, adopts above-mentionedly to exempt from the chromatograph that dilution makes linearity curve and measured; Concrete grammar is: according to formula n=C*V, take C as constant, by selector valve, select the quantity tube of different volumes to be communicated with 12 direction changeover valves, change the quantity that enters into the separating column material to obtain the solution of variable concentrations, so analyze obtain solution under variable concentrations parameter to draw out linearity curve; Wherein, C is material concentration, the volume that V is quantity tube, the quantity that n is material.
Provided by the inventionly exempt from dilution and make the chromatograph of linearity curve, by adopting the selector valve that can select different basis weights Guan Yushi bis-direction changeover valves to be communicated with, selected different quantity tubes to participate in detecting, the volume difference of each quantity tube, can enter into the quantity of separating column material by different quantity tube changes to obtain the solution of variable concentrations, according to formula n=C*V, take C as constant, the V of take measures the parameter of solution under variable concentrations as variable, in measuring process, the solution that modulates variable concentrations without operating personnel is measured, and can adopt the solution of same concentration to obtain the solution of variable concentrations by different quantity tubes in separating column, effectively avoided the precision that container and people are the error effect linearity curve that causes, realize the process of manpower-free's dilute solution, improved and exempted from the chromatographic measuring accuracy that linearity curve is made in dilution, reduced operating personnel's workload, in addition, adopt 12 direction changeover valves can connect two separating columns simultaneously, thereby can carry out stratographic analysis by corresponding detection cell, detecting device and the workstation of connecting of each separating column, realize carrying out the zwitterion test simultaneously, and without adopt two analysers to operate simultaneously, reduced use cost and effectively reduced floor area, handled easily personnel tested simultaneously, the operating process of effectively simplifying.
The accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, below will the accompanying drawing of required use in embodiment or description of the Prior Art be briefly described, apparently, accompanying drawing in the following describes is some embodiments of the present invention, for those of ordinary skills, under the prerequisite of not paying creative work, can also obtain according to these accompanying drawings other accompanying drawing.
Fig. 1 is chromatographic structural representation one in prior art;
Fig. 2 is chromatographic structural representation two in prior art;
Fig. 3 is that the present invention exempts from the structural representation one that the chromatograph embodiment of linearity curve is made in dilution;
Fig. 4 is that the present invention exempts from the structural representation two that the chromatograph embodiment of linearity curve is made in dilution;
Fig. 5 is that the present invention exempts from dilution and makes the chromatograph embodiment stator of linearity curve and the assembling schematic diagram one of rotor;
The structural representation that Fig. 6 is stator in Fig. 5;
The structural representation that Fig. 7 is Fig. 5 rotor;
Fig. 8 is that the present invention exempts from dilution and makes the chromatograph embodiment stator of linearity curve and the assembling schematic diagram two of rotor;
The structural representation that Fig. 9 is stator in Fig. 8;
The structural representation that Figure 10 is Fig. 8 rotor;
Figure 11 is that the present invention exempts from the structural representation that selector valve in the chromatograph embodiment of linearity curve is made in dilution.
Embodiment
For the purpose, technical scheme and the advantage that make the embodiment of the present invention clearer, below in conjunction with the accompanying drawing in the embodiment of the present invention, technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is the present invention's part embodiment, rather than whole embodiment.Embodiment based in the present invention, those of ordinary skills, not making under the creative work prerequisite the every other embodiment obtained, belong to the scope of protection of the invention.
As shown in Figure 3 and Figure 4, the present embodiment is exempted from the chromatograph that linearity curve is made in dilution, comprises two separating columns 104, two pumps 401 and the not isometric quantity tube 106 of Duo Gen, wherein, each separating column 104 correspondence is connected with detection cell 103, detecting device 102, workstation 101 and waste liquid barrel 105 are carried out stratographic analysis, the present embodiment is exempted to dilute the chromatograph of making linearity curve and is also comprised 12 direction changeover valves 200 and the selector valve 300 for selecting different basis weights pipe 106 to be communicated with 12 direction changeover valves 200, wherein, 12 direction changeover valves 200 along the circumferential direction are disposed with the first valve port, the second valve port, the 3rd valve port, the 4th valve port, the 5th valve port, the 6th valve port, the 7th valve port, the 8th valve port, the 9th valve port, the tenth valve port, the 11 valve port and the 12 valve port, the first valve port is connected respectively corresponding injector 500 with the 7th valve port, two separating columns 104 are connected to the 4th valve port and the 9th valve port, leacheate container 400 is by corresponding the 3rd valve port and the tenth valve port of connecting of pump 401, wherein a selector valve 300 is connected with the 11 valve port with the 8th valve port, another selector valve 300 is connected with the 5th valve port with the second valve port, and the 6th valve port is connected waste liquid barrel 105 with the 12 valve port.
Particularly, selector valve 300 in the present embodiment is for selecting different basis weights pipe 106 to be connected with 12 direction changeover valves 200, in test process, the test process of the injector 500 that is arranged in Fig. 3 below of take is example, by solution to be analyzed, the 7th valve port by 12 direction changeover valves 200 is injected into the present embodiment and exempts from dilution and do in the chromatograph of linearity curve injector 500, and solution to be analyzed enters into certain buret 106 by the selector valve 300 of top in 12 direction changeover valves 200 and Fig. 3; After quantity tube 106 is filled with solution to be analyzed, as shown in Figure 4,12 direction changeover valve 200 switching states, in Fig. 4, the leacheate container 400 in left side is injected into leacheate in 12 direction changeover valves 200 by pump 401, leacheate enters into this quantity tube 106 by 12 direction changeover valves 200 and selector valve 300 and the solution to be analyzed of quantity tube 106 is delivered to the separating column 104 in Fig. 4 left side, then by detection cell 103, detecting device 102 and workstation 101, analyzes the parameters such as appearance time, peak height and peak area of solution under this CONCENTRATION STATE.Then, select different quantity tubes 106 by selector valve 300 again, again carry out above-mentioned steps, to obtain the appearance time of solution under another CONCENTRATION STATE, the parameter such as peak height and peak area, just can be according to many groups gain of parameter of measuring linearity curve accurately, carry out linearity curve while measuring exempting from chromatograph that dilution makes linearity curve by the present embodiment, allocate the solution of multiple variable concentrations without operating personnel, effectively avoided the precision that container and people are the error effect linearity curve that causes, realize the process of manpower-free's dilute solution, improved and exempted from the chromatographic measuring accuracy that linearity curve is made in dilution.Meanwhile, the present embodiment exempts to dilute the chromatograph of making linearity curve can carry out the stratographic analysis operation by two injectors 500 simultaneously, is guaranteeing under same time and external environment state, completes synchronous stratographic analysis and measures.Wherein, to exempt from the chromatograph that dilution makes linearity curve can be ion chromatograph or liquid chromatograph to the present embodiment.
Wherein, the selector valve 300 in the present embodiment can adopt various ways, below illustrates:
As shown in Figure 5-Figure 7, selector valve 300 comprises stator 1 and rotor 2, and the center of stator 1 is provided with the first connecting hole 11, and stator 1 Shang Raoqi center is provided with a plurality of the second connecting holes 12, also is provided with the 3rd connecting hole 13 on stator 1; The center of rotor 2 is provided with the first groove 21, rotor 2 Rao Qi centers are provided with arc-shaped slot 22, the second groove 23 and the 3rd groove 24, the second groove 23 is communicated with formation the first groove 201, the three grooves 24 by the first link slot 25 arranged on rotor 2 and is communicated with arc-shaped slot 22 and forms the second groove 202 by the second link slot 26 arranged on rotor 2 with the first groove 21; Rotor 2 is attached on stator 1, and the first groove 21 is communicated with the first connecting hole 11, and the second groove 23 and the 3rd groove 24 are communicated with the second corresponding connecting hole 12, and arc-shaped slot 22 is communicated with the 3rd connecting hole 13; Many quantity tubes 106 are connected between two corresponding the second connecting holes 12, and the first connecting hole 11 is connected with 12 direction changeover valves 200 with the 3rd connecting hole 13 correspondences.Concrete, the first groove 201 and the second groove 202 will be followed rotor 2 and together be rotated, and the first groove 201 and the second groove 202 will be communicated with the second corresponding connecting hole 12.Wherein, formed the first groove 201 of the first groove 21, the first link slot 25 and the second groove 23 is an integral channel structure, and formed the second groove 202 of arc-shaped slot 22, the second link slot 26 and the 3rd groove 24 is an integral channel structure.Rotor 2 is in rotation process, and the first groove 21 in the first groove 201 will be communicated with the first connecting hole 11 all the time, thereby guarantees that the first connecting hole 11 can be communicated with second connecting hole 12 at diverse location place by the first groove 201; Meanwhile, arc-shaped slot 22 in the second groove 202 can be communicated with the 3rd connecting hole 13 all the time, thereby guarantee that the 3rd connecting hole 13 can be communicated with second connecting hole 12 at diverse location place by the second groove 202, realize that selector valve 300 can realize multiple mode of communicating, can connect as required many quantity tubes 106 on stator 1, and realize selecting as required specific quantity tube 106 to be connected with 12 direction changeover valves 200.For example: it is example that the stator 1 of take in accompanying drawing 6 has 12 the second connecting holes 12, on the stator 1 in accompanying drawing 6, can be connected with six roots of sensation quantity tube 106, thereby realize six kinds of mode of communicating.Further, in order to reduce the friction force between stator 1 and rotor 2, be provided with boss structure 10, the first connecting holes 11, the second connecting hole 12 and the 3rd connecting hole 13 on stator 1 and be distributed on the surface of boss structure 10, rotor 2 is attached on the surface of boss structure 10.Concrete, boss structure 10 on stator 1 contacts with rotor 2, effectively reduced the contact area between rotor 2 and stator 1, rotor 2 is with after boss structure 10 contacts, and by the surface of contact between rotor 2 and boss structure 10, seals up groove structure on rotor 2 and the pore structure on stator 1.Preferably, the stator 1 in the present embodiment and rotor 2 can adopt polyetheretherketone (be called for short: PEEK) high-abrasive material such as resin, nylon is made, and with more effective reduction friction factor, reduces wear.In addition, when selector valve 300 during for high-pressure valve, the diameter of the first connecting hole 11, the second connecting hole 12 and the 3rd connecting hole 13 in the present embodiment can be 0.1mm ~ 1.5mm, the groove width of the first groove 201 and the second groove 202 can be 0.1mm ~ 1.5mm, and the groove depth of the first groove 201 and the second groove 202 can be 0.1mm ~ 1.5mm.Further again, for fear of the remaining liquid of the tail end that arc-shaped slot 22 occurs, be provided with the auxiliary circle deep-slotted chip breaker 131 be communicated with the 3rd connecting hole 13 on stator 1, the radius of auxiliary circle deep-slotted chip breaker 131 is identical with the radius of arc-shaped slot 22, and arc-shaped slot 22 is communicated with the 3rd connecting hole 13 by auxiliary circle deep-slotted chip breaker 131.Concrete, after rotor 2 is fitted on stator 1, the tail end of arc-shaped slot 22 will overlap with auxiliary circle deep-slotted chip breaker 131, liquid in arc-shaped slot 22 will enter into the 3rd connecting hole 13 by auxiliary circle deep-slotted chip breaker 131, due in rotor 2 rotation processes, the tail end of arc-shaped slot 22 will overlap with auxiliary circle deep-slotted chip breaker 131 all the time, avoids occurring the remaining liquid of tail end of arc-shaped slot 22, has improved the precision of selector valve 300.Preferably, the arc length of auxiliary circle deep-slotted chip breaker 131 is not less than the arc length of arc-shaped slot 22.
Same, shown in Fig. 8-Figure 10, selector valve 300 comprises stator 1 and rotor 2, the center of stator 1 is provided with the first connecting hole 11, stator 1 Shang Raoqi center is provided with two first connecting holes 11 and several second connecting holes 12, rotor 2 Rao Qi centers are provided with the arc-shaped slot 22 corresponding with the first connecting hole 11, also are provided with the groove corresponding with arc-shaped slot 22 21 and link slot 23 on rotor 2, and groove 21 is communicated with arc-shaped slot 22 and forms groove structure 201 by link slot 23; Rotor 2 is attached on stator 1, and arc-shaped slot 22 is communicated with the first corresponding connecting hole 13, and groove 21 is communicated with the second corresponding connecting hole 12; Many quantity tubes 106 are connected between two corresponding the second connecting holes 12, and two the first connecting holes 11 are connected with 12 direction changeover valves 200.Concrete, groove structure 201 will be followed rotor 2 and together be rotated, and groove structure 201 will be communicated with the second corresponding connecting hole 12.Wherein, the formed groove structure 201 of groove 21, link slot 23 and arc-shaped slot 22 is an integral channel structure.Rotor 2 is in rotation process, and groove structure 201 remains connected state by arc-shaped slot 22 with the first corresponding connecting hole 11, thereby guarantees that this first connecting hole 11 can be communicated with second connecting hole 12 at diverse location place by groove structure 201; Meanwhile, another groove structure 201 also will be communicated with second connecting hole 12 at corresponding diverse location place, realize that selector valve 300 can realize multiple mode of communicating, can connect as required many quantity tubes 106 on stator 1, and realize selecting as required specific quantity tube 106 and being connected with 12 direction changeover valves 200.For example: it is example that the stator 1 of take in accompanying drawing 9 has 12 the second connecting holes 12, on the stator 1 in accompanying drawing 9, can be connected with six roots of sensation quantity tube, thereby realize six kinds of mode of communicating.Further, in order to reduce the friction force between stator 1 and rotor 2, be provided with boss structure 10, the first connecting holes 11 and the second connecting hole 12 on stator 1 and be distributed on the surface of boss structure 10, rotor 2 is attached on the surface of boss structure 10.Concrete, boss structure 10 on stator 1 contacts with rotor 2, effectively reduced the contact area between rotor 2 and stator 1, rotor 2 is with after boss structure 10 contacts, and by the surface of contact between rotor 2 and boss structure 10, seals up groove structure on rotor 2 and the pore structure on stator 1.Preferably, the stator 1 in the present embodiment and rotor 2 can adopt polyetheretherketone (be called for short: PEEK) high-abrasive material such as resin, nylon is made, and with more effective reduction friction factor, reduces wear.In addition, when selector valve 300 during for high-pressure valve, the first connecting hole 11 in the present embodiment and the diameter of the second connecting hole 12 can be 0.1mm ~ 1.5mm, and the groove width of groove structure 201 can be 0.1mm ~ 1.5mm, and the groove depth of groove structure 201 can be 0.1mm ~ 1.5mm.Further again, as Figure 8-Figure 10, for fear of the remaining liquid of the tail end that arc-shaped slot 22 occurs, be provided with the auxiliary circle deep-slotted chip breaker 111 be communicated with corresponding the first connecting hole 11 on stator 1, the radius of auxiliary circle deep-slotted chip breaker 111 is identical with the radius of corresponding arc-shaped slot 22, and arc-shaped slot 22 is communicated with the first connecting hole 11 by auxiliary circle deep-slotted chip breaker 111.Concrete, after rotor 2 is fitted on stator 1, the tail end of arc-shaped slot 22 will overlap with auxiliary circle deep-slotted chip breaker 111, liquid in arc-shaped slot 22 will enter into the first connecting hole 11 by auxiliary circle deep-slotted chip breaker 111, due in rotor 2 rotation processes, the tail end of arc-shaped slot 22 will overlap with auxiliary circle deep-slotted chip breaker 111 all the time, avoids occurring the remaining liquid of tail end of arc-shaped slot 22, has improved the precision of selector valve 300.Preferably, the arc length of auxiliary circle deep-slotted chip breaker 111 is not less than the arc length of corresponding with it arc-shaped slot 22.
Wherein, as shown in Figure 6, the center of circle of the second connecting hole 12 in the present embodiment is distributed in take on the circular trace that the center of stator 1 is the center of circle, concrete, and the second connecting hole 12 is distributed in take on the same circular trace that the center of stator 1 is the center of circle.Perhaps, as shown in Figure 9, a plurality of the second connecting holes are divided into a plurality of the second connecting holes 1 and a plurality of the second connecting hole 2 122, the center of circle of a plurality of the second connecting holes 1 is distributed in take the center of stator 1 on the circular trace that center of circle radius is r1, the center of circle of a plurality of the second connecting holes 2 122 is distributed in take the center of stator 1 on the circular trace that center of circle radius is r2, wherein, r1 is not equal to r2.And be attached on stator 1 in rotation process being centered close on same straight line of the center of circle of the rotation of rotor 2, arc-shaped slot 22 and stator 1 at rotor 2.
As shown in figure 11, selector valve 300 can be also hand valve for motorized valve, selector valve 300 is not limited its type of drive, in addition, selector valve 300 can be high-pressure valve, can be also low pressure valve, selector valve 300 is not limited its environment for use, selector valve 300 be take motorized valve and is described as the assembly relation of example to stator 1 and rotor 2, and the stator 1 in selector valve 300 and rotor 2 are arranged in shell 4 usually, and motor 5 drives rotors 2 to rotate.Further, also be fixedly connected with valve head 3 on stator 1, the center of valve head 3 is provided with the first external tapping and/or the 3rd external tapping (not shown), valve head 3 Shang Raoqi centers are provided with a plurality of the second external tappings 31, the second external tapping 31 is communicated with corresponding the second connecting hole 12, and a plurality of the second external tappings 31 are the divergent shape setting or a plurality of the second external tapping 31 is distributed on the circumferential side wall of valve head 3 along inside surface to the outside surface direction of valve head 3.Concrete, the second external tapping 31 is the divergent shape setting on valve head 3, thereby when occurring that the second connecting hole 12 occurs to stop up, can adopt fine needle to be inserted in the second connecting hole 12 and to be cleared up along the second external tapping 31, thereby, without dismounting selector valve 300, just can clear up easily the second connecting hole 12 of blocking.And the second external tapping 31 is distributed on the circumferential side wall of valve head 3, the xsect of the second external tapping 31 is the L-type structure, more convenient processing.
The present invention also provides a kind of linearity curve measuring method, adopts above-mentionedly to exempt from the chromatograph that dilution makes linearity curve and measured; Concrete grammar is: according to formula n=C*V, take C as constant, by selector valve, select the quantity tube of different volumes to be communicated with 12 direction changeover valves, change the quantity that enters into the separating column material to obtain the solution of variable concentrations, so analyze obtain solution under variable concentrations parameter to draw out linearity curve; Wherein, C is material concentration, the volume that V is quantity tube, the quantity that n is material.
Provided by the inventionly exempt from dilution and make chromatograph and the linearity curve measuring method of linearity curve, by adopting the selector valve that can select different basis weights Guan Yushi bis-direction changeover valves to be communicated with, selected different quantity tubes to participate in detecting, the volume difference of each quantity tube, can enter into the quantity of separating column material by different quantity tube changes to obtain the solution of variable concentrations, according to formula n=C*V, take C as constant, the V of take measures the parameter of solution under variable concentrations as variable, in measuring process, the solution that modulates variable concentrations without operating personnel is measured, and can adopt the solution of same concentration to obtain the solution of variable concentrations by different quantity tubes in separating column, effectively avoided the precision that container and people are the error effect linearity curve that causes, realize the process of manpower-free's dilute solution, improved and exempted from the chromatographic measuring accuracy that linearity curve is made in dilution, reduced operating personnel's workload, in addition, adopt 12 direction changeover valves can connect two separating columns simultaneously, thereby can carry out stratographic analysis by corresponding detection cell, detecting device and the workstation of connecting of each separating column, realize carrying out the zwitterion test simultaneously, and without adopt two analysers to operate simultaneously, reduced use cost and effectively reduced floor area, handled easily personnel tested simultaneously, the operating process of effectively simplifying.
Finally it should be noted that: above embodiment only, in order to technical scheme of the present invention to be described, is not intended to limit; Although with reference to previous embodiment, the present invention is had been described in detail, those of ordinary skill in the art is to be understood that: its technical scheme that still can put down in writing aforementioned each embodiment is modified, or part technical characterictic wherein is equal to replacement; And these modifications or replacement do not make the essence of appropriate technical solution break away from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (10)
1. exempt from the chromatograph that linearity curve is made in dilution for one kind, it is characterized in that, comprise two separating columns, two pumps, many quantity tubes, 12 direction changeover valves and two selector valves for selecting different described quantity tubes to be communicated with described 12 direction changeover valves, described separating column, described pump and described selector valve are connected with described 12 direction changeover valves respectively, and each described selector valve is connected with many described quantity tubes.
2. according to claim 1ly exempt from dilution and make the chromatograph of linearity curve, it is characterized in that, described selector valve comprises stator and rotor, the center of described stator is provided with the first connecting hole, described stator Shang Raoqi center is provided with a plurality of the second connecting holes, also is provided with the 3rd connecting hole on described stator; The center of described rotor is provided with the first groove, described rotor Rao Qi center is provided with arc-shaped slot, the second groove and the 3rd groove, described the second groove is communicated with described the first groove and forms the first groove by the first link slot arranged on described rotor, and described the 3rd groove is communicated with described arc-shaped slot and forms the second groove by the second link slot arranged on described rotor; Described rotor is attached on described stator, and described the first groove is communicated with described the first connecting hole, and described the second groove and described the 3rd groove are communicated with corresponding described the second connecting hole, and described arc-shaped slot is communicated with described the 3rd connecting hole; Many described quantity tubes are connected between two corresponding described the second connecting holes, and described the first connecting hole is connected with described 12 direction changeover valves with described the 3rd connecting hole.
3. according to claim 2ly exempt from dilution and make the chromatograph of linearity curve, it is characterized in that, be provided with the auxiliary circle deep-slotted chip breaker be communicated with described the 3rd connecting hole on described stator, the radius of described auxiliary circle deep-slotted chip breaker is identical with the radius of described arc-shaped slot, and described arc-shaped slot is communicated with described the 3rd connecting hole by described auxiliary circle deep-slotted chip breaker.
4. according to claim 2ly exempt from dilution and make the chromatograph of linearity curve, it is characterized in that, also be fixedly connected with valve head on described stator, the center of described valve head is provided with the first external tapping, described valve head Shang Raoqi center is provided with a plurality of the second external tappings, also be provided with the 3rd external tapping on described valve head, described the first external tapping is communicated with described the first connecting hole, described the second external tapping is communicated with corresponding described the second connecting hole, described the 3rd external tapping is communicated with corresponding described the 3rd connecting hole, a plurality of described the second external tappings are the divergent shape setting or a plurality of described the second external tapping is distributed on the circumferential side wall of described valve head along inside surface to the outside surface direction of described valve head.
5. according to claim 1 exempting from diluted the chromatograph of making linearity curve, it is characterized in that, described selector valve comprises stator and rotor, and described stator Shang Raoqi center is provided with two the first connecting holes and several second connecting holes; Described rotor Rao Qi center is provided with the arc-shaped slot corresponding with described the first connecting hole, also is provided with the groove corresponding with described arc-shaped slot and link slot on described rotor, and described groove is communicated with described arc-shaped slot and forms groove structure by described link slot; Described rotor is attached on described stator, and described arc-shaped slot is communicated with corresponding described the first connecting hole, and described groove is communicated with corresponding described the second connecting hole; Many described quantity tubes are connected between two corresponding described the second connecting holes, and two described the first connecting holes are connected with described 12 direction changeover valves.
6. according to claim 5ly exempt from dilution and make the chromatograph of linearity curve, it is characterized in that, be provided with the auxiliary circle deep-slotted chip breaker corresponding with described the first connecting hole on described stator, described auxiliary circle deep-slotted chip breaker is communicated with described the first connecting hole, the radius of described auxiliary circle deep-slotted chip breaker is identical with the radius of corresponding described arc-shaped slot, and described arc-shaped slot is communicated with described the first connecting hole by described auxiliary circle deep-slotted chip breaker.
7. according to claim 5ly exempt from dilution and make the chromatograph of linearity curve, it is characterized in that, also be fixedly connected with valve head on described stator, be provided with first external tapping corresponding with described the first connecting hole on described valve head, described valve head Shang Raoqi center is provided with the second external tapping that a plurality of and described the second connecting hole is corresponding, described the first external tapping is communicated with corresponding described the first connecting hole, described the second external tapping is communicated with corresponding described the second connecting hole, a plurality of described the second external tappings are the divergent shape setting or a plurality of described the second external tapping is distributed on the circumferential side wall of described valve head along inside surface to the outside surface direction of described valve head.
8. describedly exempt from dilution and make the chromatograph of linearity curve according to claim 2-7 is arbitrary, it is characterized in that, the center of circle of described the second connecting hole is distributed in take on the circular trace that the center of described stator is the center of circle.
9. according to the arbitrary described chromatograph that linearity curve is made in dilution of exempting from of claim 2-7, it is characterized in that, be provided with boss structure on described stator, described rotor is attached on the surface of described boss structure.
10. a linearity curve measuring method, is characterized in that, adopts as arbitraryly as claim 1-9 describedly to exempt from the chromatograph that dilution makes linearity curve and measured; Concrete grammar is: according to formula n=C*V, take C as constant, by selector valve, select the quantity tube of different volumes to be communicated with 12 direction changeover valves, change the quantity that enters into the separating column material to obtain the solution of variable concentrations, so analyze obtain solution under variable concentrations parameter to draw out linearity curve; Wherein, C is material concentration, the volume that V is quantity tube, the quantity that n is material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310412985.4A CN103439432B (en) | 2013-09-11 | 2013-09-11 | Dilution-free linear curve chromatograph and linear curve measuring method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310412985.4A CN103439432B (en) | 2013-09-11 | 2013-09-11 | Dilution-free linear curve chromatograph and linear curve measuring method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103439432A true CN103439432A (en) | 2013-12-11 |
| CN103439432B CN103439432B (en) | 2015-04-01 |
Family
ID=49693135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310412985.4A Active CN103439432B (en) | 2013-09-11 | 2013-09-11 | Dilution-free linear curve chromatograph and linear curve measuring method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103439432B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103439433A (en) * | 2013-09-11 | 2013-12-11 | 青岛普仁仪器有限公司 | Dilution-free linear curve chromatograph and linear curve measuring method |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4158630A (en) * | 1978-02-24 | 1979-06-19 | Stearns Stanley D | Chromatographic multi-sample valving apparatus |
| JP2005003558A (en) * | 2003-06-12 | 2005-01-06 | Shiseido Co Ltd | Liquid chromatography apparatus and method of analyzing optical isomer contained in sample |
| WO2008140377A1 (en) * | 2007-05-15 | 2008-11-20 | Ge Healthcare Bio-Sciences Ab | Random access rotary valve |
| CN102333954A (en) * | 2009-02-27 | 2012-01-25 | 沃特世科技公司 | Automated dilution for liquid chromatography |
| CN102918309A (en) * | 2010-05-20 | 2013-02-06 | 生物辐射实验室股份有限公司 | Rotary column selector valve |
| CN102967681A (en) * | 2012-11-26 | 2013-03-13 | 中国科学院青岛生物能源与过程研究所 | Multi-dimensional ion chromatographic analysis system |
-
2013
- 2013-09-11 CN CN201310412985.4A patent/CN103439432B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4158630A (en) * | 1978-02-24 | 1979-06-19 | Stearns Stanley D | Chromatographic multi-sample valving apparatus |
| JP2005003558A (en) * | 2003-06-12 | 2005-01-06 | Shiseido Co Ltd | Liquid chromatography apparatus and method of analyzing optical isomer contained in sample |
| WO2008140377A1 (en) * | 2007-05-15 | 2008-11-20 | Ge Healthcare Bio-Sciences Ab | Random access rotary valve |
| CN102333954A (en) * | 2009-02-27 | 2012-01-25 | 沃特世科技公司 | Automated dilution for liquid chromatography |
| CN102918309A (en) * | 2010-05-20 | 2013-02-06 | 生物辐射实验室股份有限公司 | Rotary column selector valve |
| CN102967681A (en) * | 2012-11-26 | 2013-03-13 | 中国科学院青岛生物能源与过程研究所 | Multi-dimensional ion chromatographic analysis system |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103439433A (en) * | 2013-09-11 | 2013-12-11 | 青岛普仁仪器有限公司 | Dilution-free linear curve chromatograph and linear curve measuring method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103439432B (en) | 2015-04-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US9903835B2 (en) | Fully automated high-precision capillary electrophoresis instrument | |
| CN101782587B (en) | Instrument system suitable for synchronous on-line detection of adsorption spectrum and fluorescence spectrum | |
| CN104062170B (en) | Automatic on-line micro-example dilution mixture system and mixed method | |
| CN203465249U (en) | Dilution-free linearity curve drawing chromatographic instrument | |
| CN203241404U (en) | Automatic multi-parameter chemical reagent filling device of water quality online analyzer | |
| CN104792769A (en) | Dynamic micro-extraction and detection integrated device and method for compounds in aqueous solution sample | |
| US5567307A (en) | System and a method for using a small suppressor column in performing liquid chromatography | |
| CN203465247U (en) | Dilution-free linearity curve drawing chromatographic instrument | |
| CN103439432B (en) | Dilution-free linear curve chromatograph and linear curve measuring method | |
| CN203465248U (en) | Dilution-free linearity curve drawing chromatographic instrument | |
| CN104237418B (en) | Exempt to dilute the chromatograph and linearity curve measuring method of making linearity curve | |
| Giné et al. | Interfacing flow injection with capillary electrophoresis and inductively coupled plasma mass spectrometry for Cr speciation in water samples | |
| CN201364336Y (en) | Dedicated metering device for automatic water quality analyzer | |
| CN208505986U (en) | A kind of high performance liquid chromatograph with liquid storage bottle clamp system | |
| CN203908852U (en) | Automatic online micro sample diluting and mixing system | |
| CN104267198A (en) | Automatic calibration device and method for volatile organic compound analyzer | |
| CN203908853U (en) | Automatic online micro-sample diluting and mixing system | |
| CN211603025U (en) | Capillary electrophoresis apparatus for water environment field monitoring | |
| CN208579806U (en) | A kind of liquid-volume measurement apparatus | |
| CN208127137U (en) | A kind of two-way sample injector | |
| CN108519254A (en) | sampling flow control device and gas analyzer | |
| CN204925057U (en) | Survey device of post switching time parameter based on switching column technique | |
| CN114545014B (en) | Double-channel sample introduction system | |
| CN108444562A (en) | A kind of liquid-volume measurement apparatus | |
| CN204705625U (en) | A kind of analysis measuring apparatus and liquid analysis system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |