CN103432507A - Medicinal composition for treating hand-foot-mouth disease - Google Patents
Medicinal composition for treating hand-foot-mouth disease Download PDFInfo
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- CN103432507A CN103432507A CN2013104186310A CN201310418631A CN103432507A CN 103432507 A CN103432507 A CN 103432507A CN 2013104186310 A CN2013104186310 A CN 2013104186310A CN 201310418631 A CN201310418631 A CN 201310418631A CN 103432507 A CN103432507 A CN 103432507A
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Abstract
The invention relates to a medicinal composition for treating hand-foot-mouth disease. The medicinal composition is a preparation prepared from the following medicinal raw materials: ovateleaf holly bark, Chinese date, pawpaw, garlic, mungbean, indigoplant, liquidambar formosana hance, rose, radix tinosporae, Chinese mosla herb, melia toosendan, vine of multiflower knotweed, scorpion, concha haliotidis, platycodon grandiflorum, fructus chebulae immaturus, lophatherum gracile, dayflower, yam, potentilla chinensis, Chinese azalea flower, rhizoma bolbostemmae, dodder, Chinese violet, cockscomb, longan pulp, cortex dictamni, sedum sarmentosum, gordon euryale, mulberry twig, fructus polygoni orientalis, pine nodular branch, humifuse euphorbia herb, loquat leaf, stalactite, chingma abutilon seed, Chinese starjasmine stem, zaocys dhumnade, himalayan teasel root, honeysuckle stem, folium turpiniae, hawthorn, amomum tsao-ko, valeriana jatamansi jones, spina gleditsiae, camuning, lotus stamen, marmor serpentinatum, lindley eupatorium herb, swertia mileensis and Chinese waxgourd peel. The medicinal composition is reasonable in prescription, has definite curative effect, and can be used for effectively treating hand-foot-mouth disease.
Description
Technical field
The present invention relates to the prevention and control of diseases field, specifically, relate to a kind of pharmaceutical composition for the treatment of hand-foot-mouth disease.
Background technology
Hand-foot-mouth disease is the intestinal infection disease caused by multiple enterovirus, and infectiousness is strong, propagates rapidly, and route of transmission is wide, popular extensive, can cause and be very popular at short notice.Its morbidity has the trend of increasing in recent years.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition for the treatment of hand-foot-mouth disease.
In order to realize purpose of the present invention, the invention provides a kind of pharmaceutical composition for the treatment of hand-foot-mouth disease, it is the medicament of being made by weight by following bulk drugs: 4 parts of Cortex Ilicis Rotundaes, 9 parts, Fructus Jujubae, 3 parts of Fructus Chaenomeliss, 6 parts, Bulbus Allii, 8 parts, Semen phaseoli radiati, 3 parts of Folium Polygoni Tinctoriis, 4 parts of Fructus Liquidambaris, 4 parts of Flos Rosae Rugosaes, 2 parts of Radix Tinosporaes, 7 parts of Herba Moslaes, 4 parts of Fructus Toosendans, 4 parts of Caulis Polygoni Multiflori, 8 parts of Scorpios, 3 parts of Concha Haliotidis, 2 parts of Radix Platycodoniss, 8 parts of FRUCTUS TERMINALIAE IMMATURUS, 4 parts of Herba Lophatheris, 9 parts of Herba Commelinaes, 2 parts of Rhizoma Dioscoreaes, 8 parts of Herba Potentillae Chinensis, 6 parts of Flos Rhododendri Mollis, 4 parts of Rhizoma Bolbostematiss, 3 parts of Semen Cuscutae, 4 parts of Herba Violaes, 4 parts of Flos Celosiae Cristataes, 2 parts of Arillus Longans, 6 parts of Cortex Dictamni, 8 parts of Herba Sedis, 7 parts of Semen Euryaless, 9 parts of Ramulus Moris, 7 parts of Fructus Polygoni Orientaliss, 3 parts of Pine Nodular Branchs, 2 parts of Herba Euphorbiae Humifusaes, 2 parts of Folium Eriobotryaes, 2 parts of Stalactitums, 9 parts of Semen Abutili, 8 parts of Caulis Trachelospermis, 7 parts of Zaocyss, 6 parts of Radix Dipsacis, 4 parts of Caulis Loniceraes, 2 parts of leaf of Turpinia pomifera (Roxb) D O., 8 parts of Fructus Crataegis, 3 parts of Fructus Tsaokos, 2 parts of Rhizoma valerianae latifoliaes, 3 parts of Spina Gleditsiaes, 3 parts of Folium Et Cacumen Murrayae, 7 parts of Stamen Nelumbiniss, 2 parts of Ophicalcitums, 8 parts of Herba Eupatorii Lindleyanis, 4 parts of 2 parts of Herba Swertiae Mileensises and Exocarpium Benincasaes.
Pharmaceutical composition of the present invention can be made various dosage forms with pharmaceutically acceptable carrier, such as tablet, capsule, soft capsule, pill, granule, oral liquid or decoction etc.Can adopt preparation technique means well known in the art to complete the preparation of pharmaceutical composition of the present invention.
Described pharmaceutically acceptable carrier is well known, is the conventional excipients for the preparation of above-mentioned preparation or adjuvant.Excipient or adjuvant commonly used comprises (but being not limited to) filler, lubricant, dispersant, wetting agent, binding agent, antioxidant etc., for example, syrup, arabic gum, sorbitol, lactose, dextrin, starch, calcium carbonate, Pulvis Talci, Polyethylene Glycol, carboxymethyl starch sodium, magnesium stearate etc.
The reasonable recipe of pharmaceutical composition of the present invention, curative effect is clear and definite, can effectively treat hand-foot-mouth disease.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 drug composition oral liquid of the present invention
Take Cortex Ilicis Rotundae 4 grams, Fructus Jujubae 9 grams, Fructus Chaenomelis 3 grams, Bulbus Allii 6 grams, Semen phaseoli radiati 8 grams, Folium Polygoni Tinctorii 3 grams, Fructus Liquidambaris 4 grams, Flos Rosae Rugosae 4 grams, Radix Tinosporae 2 grams, Herba Moslae 7 grams, Fructus Toosendan 4 grams, Caulis Polygoni Multiflori 4 grams, Scorpio 8 grams, Concha Haliotidis 3 grams, Radix Platycodonis 2 grams, FRUCTUS TERMINALIAE IMMATURUS 8 grams, Herba Lophatheri 4 grams, Herba Commelinae 9 grams, Rhizoma Dioscoreae 2 grams, Herba Potentillae Chinensis 8 grams, Flos Rhododendri Mollis 6 grams, Rhizoma Bolbostematis 4 grams, Semen Cuscutae 3 grams, Herba Violae 4 grams, Flos Celosiae Cristatae 4 grams, Arillus Longan 2 grams, Cortex Dictamni 6 grams, Herba Sedi 8 grams, Semen Euryales 7 grams, Ramulus Mori 9 grams, Fructus Polygoni Orientalis 7 grams, Pine Nodular Branch 3 grams, Herba Euphorbiae Humifusae 2 grams, Folium Eriobotryae 2 grams, Stalactitum 2 grams, Semen Abutili 9 grams, Caulis Trachelospermi 8 grams, Zaocys 7 grams, Radix Dipsaci 6 grams, Caulis Lonicerae 4 grams, leaf of Turpinia pomifera (Roxb) D O. 2 grams, Fructus Crataegi 8 grams, Fructus Tsaoko 3 grams, Rhizoma valerianae latifoliae 2 grams, Spina Gleditsiae 3 grams, Folium Et Cacumen Murrayae 3 grams, Stamen Nelumbinis 7 grams, Ophicalcitum 2 grams, Herba Eupatorii Lindleyani 8 grams, Herba Swertiae Mileensis 2 grams and Exocarpium Benincasae 4 grams, add 8000 ml waters, 80 ℃ of heating 5 hours, filters, and filtrate is concentrated into 3000ml, high speed centrifugation, and filtering with microporous membrane, in embedding to 500 bottle, sterilizing and get final product.
Experimental example
Physical data
Be chosen in hand-foot-mouth disease infant 20 examples of my section's outpatient clinic, male 10 examples, female's 10 examples, age 3-7 year.All infants all have classical symptom and the sign of hand-foot-mouth disease, meet Ministry of Public Health " hand-foot-mouth disease practice guidelines (version in 2010) " diagnostic criteria (Ministry of Health of the People's Republic of China. hand-foot-mouth disease practice guidelines (version in 2010) [S]. Beijing .2010), without severe cases, and get rid of the infant of morbidity natural law >=5 day.Clinical manifestation has heating in various degree except symptom, and body temperature fluctuates outside 37.7 ℃-39.2 ℃, all has brothers' erythra and oral mucosa herpes in various degree, and the minority infant merges enteritis.
Therapeutic scheme
Oral liquid described in oral embodiment 1, one day twice, each one bottle.Treatment is 15 days continuously.
Observation index
Observe infant brothers' deflorescence time, herpes of mouth healing time, heat and move back time and total course of disease, therapeutic effect.
Efficacy assessment standard
Produce effects: temperature recovery is normal, and deflorescence occurs without new erythra, and infant is without other complication.Effectively: body temperature is basicly stable, and deflorescence is dispersed in the erythra appearance but still have, without other severe complications.Invalid: still heating, erythra does not disappear or increases the weight of, and other complication occur.
Therapeutic outcome:
Through treatment, find the temperature recovery normal (36.7-37.1 ℃) of all patients, deflorescence occurs that without new erythra infant, without other complication, therefore all meets the standard of produce effects.
Claims (2)
1. a pharmaceutical composition for the treatment of hand-foot-mouth disease, is characterized in that, it is the medicament of being made by weight by following bulk drugs: 4 parts of Cortex Ilicis Rotundaes, 9 parts, Fructus Jujubae, 3 parts of Fructus Chaenomeliss, 6 parts, Bulbus Allii, 8 parts, Semen phaseoli radiati, 3 parts of Folium Polygoni Tinctoriis, 4 parts of Fructus Liquidambaris, 4 parts of Flos Rosae Rugosaes, 2 parts of Radix Tinosporaes, 7 parts of Herba Moslaes, 4 parts of Fructus Toosendans, 4 parts of Caulis Polygoni Multiflori, 8 parts of Scorpios, 3 parts of Concha Haliotidis, 2 parts of Radix Platycodoniss, 8 parts of FRUCTUS TERMINALIAE IMMATURUS, 4 parts of Herba Lophatheris, 9 parts of Herba Commelinaes, 2 parts of Rhizoma Dioscoreaes, 8 parts of Herba Potentillae Chinensis, 6 parts of Flos Rhododendri Mollis, 4 parts of Rhizoma Bolbostematiss, 3 parts of Semen Cuscutae, 4 parts of Herba Violaes, 4 parts of Flos Celosiae Cristataes, 2 parts of Arillus Longans, 6 parts of Cortex Dictamni, 8 parts of Herba Sedis, 7 parts of Semen Euryaless, 9 parts of Ramulus Moris, 7 parts of Fructus Polygoni Orientaliss, 3 parts of Pine Nodular Branchs, 2 parts of Herba Euphorbiae Humifusaes, 2 parts of Folium Eriobotryaes, 2 parts of Stalactitums, 9 parts of Semen Abutili, 8 parts of Caulis Trachelospermis, 7 parts of Zaocyss, 6 parts of Radix Dipsacis, 4 parts of Caulis Loniceraes, 2 parts of leaf of Turpinia pomifera (Roxb) D O., 8 parts of Fructus Crataegis, 3 parts of Fructus Tsaokos, 2 parts of Rhizoma valerianae latifoliaes, 3 parts of Spina Gleditsiaes, 3 parts of Folium Et Cacumen Murrayae, 7 parts of Stamen Nelumbiniss, 2 parts of Ophicalcitums, 8 parts of Herba Eupatorii Lindleyanis, 4 parts of 2 parts of Herba Swertiae Mileensises and Exocarpium Benincasaes.
2. the pharmaceutical composition for the treatment of hand-foot-mouth disease according to claim 1, is characterized in that, described medicament can be tablet, capsule, soft capsule, pill, granule, oral liquid or decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013104186310A CN103432507A (en) | 2013-09-16 | 2013-09-16 | Medicinal composition for treating hand-foot-mouth disease |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013104186310A CN103432507A (en) | 2013-09-16 | 2013-09-16 | Medicinal composition for treating hand-foot-mouth disease |
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| CN103432507A true CN103432507A (en) | 2013-12-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2013104186310A Pending CN103432507A (en) | 2013-09-16 | 2013-09-16 | Medicinal composition for treating hand-foot-mouth disease |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105012729A (en) * | 2015-07-09 | 2015-11-04 | 杜仁波 | Traditional Chinese medicine composition for treating hand-foot-and-mouth disease |
| CN116019823A (en) * | 2023-03-28 | 2023-04-28 | 吉林华康药业股份有限公司 | Pharmaceutical composition for treating children hand-foot-mouth disease and application of pharmaceutical composition |
-
2013
- 2013-09-16 CN CN2013104186310A patent/CN103432507A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105012729A (en) * | 2015-07-09 | 2015-11-04 | 杜仁波 | Traditional Chinese medicine composition for treating hand-foot-and-mouth disease |
| CN116019823A (en) * | 2023-03-28 | 2023-04-28 | 吉林华康药业股份有限公司 | Pharmaceutical composition for treating children hand-foot-mouth disease and application of pharmaceutical composition |
| CN116019823B (en) * | 2023-03-28 | 2023-05-30 | 吉林华康药业股份有限公司 | Pharmaceutical composition for treating children hand-foot-mouth disease and application of pharmaceutical composition |
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Application publication date: 20131211 |