CN103432484B - 一种治疗白塞病的中药 - Google Patents
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Abstract
本发明涉及一种治疗白塞病的中药，其特征在于：它是由以下重量的药材组成：甘草50g、白花蛇舌草50g、女贞子20g、天名精30g、白菊花根30g、芦根30g、败酱草30g、大黄6g、三棱20g、桃仁5g、人参30g、牡丹皮15g、天花粉20g、土鳖虫20g。实验证明，本发明能够安全有效治疗白塞病。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗白塞病的中药。
背景技术
白塞病是一种全身性免疫系统疾病，可侵害人体多个器官，包括口腔、皮肤、关节肌肉、眼睛、血管、心脏、肺和神经系统等，主要表现为反复口腔和会阴部溃疡、皮疹、下肢结节红斑、眼部虹膜炎、食道溃疡、小肠或结肠溃疡及关节肿痛等，需要规律的药物治疗，包括各种调节免疫的药物，不治疗则预后不好，严重者危及生命。目前临床尚缺乏公认安全有效的治疗药物。
本发明中药所涉及药材的来源及应用现状如下：
甘草：性味与归经：甘，平。归心、肺、脾、胃经。功能与主治：补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
白花蛇舌草：性味与归经：苦、甘、寒。归大肠经。功能与主治：清热解毒，利湿，用于胃癌，食道癌，直肠癌，肠痈，疮疔肿毒，咽喉肿痛，毒蛇咬伤，热淋，小便不利。
女贞子：性味与归经：甘、苦，凉。归肝、肾经。功能与主治：滋补肝肾，明目乌发。用于眩晕耳鸣，腰膝酸软，须发早白，目暗不明。
天名精：【性味】味苦；辛；性寒。【归经】归肝；肺经。【功能主治】清热；化痰；解毒；杀虫；破瘀；止血。主乳蛾、喉痹、急慢惊风、牙痛、疔疮肿毒、痔瘘、皮肤痒疹；毒蛇咬伤；虫积；血瘕；吐血；衄血；血淋；创伤出血。
白菊花根：功能主治①《本草正》：善利水，捣汁和酒服之，大治癃闭。②《纲目拾遗》：治疔肿，喉疔，喉癣。
芦根：性味与归经：甘，寒。归肺、胃经。功能与主治：清热生津，止呕，利尿之功。用于烦热口渴，胃热呕逆，肺热咳嗽，肺痈，小便短赤或热淋。
败酱草：性味与归经：味辛、苦，微寒。归肝、胃、大肠经。功能与主治：清热解毒，消痈排脓，祛瘀止痛。用于肠痈，肺痈高热，咳吐脓血，热毒疮疔，胸腹疼痛，产后腹痛，痛经。
三棱：【性味归经】苦，平。归肝、脾经。【功能】破血行气，消积止痛。
桃仁：【性味】苦甘；平；无毒。【归经】心；肝；大肠；肺；脾经。【功能主治】破血行瘀；润燥滑肠。主经闭；癥瘕；热病蓄血；风痹；疟疾；跌打损伤；瘀血肿痛；血燥便秘。
大黄：【性味】苦，寒。【归经】归脾、胃、大肠、肝、心包经。【功能主治】泻热通肠，凉血解毒，逐瘀通经。用于实热便秘，积滞腹痛，泻痢不爽，湿热黄疸，血热吐衄，目赤，咽肿，肠痈腹痛，痈肿疔疮，瘀血经闭，跌打损伤，外治水火烫伤；上消化道出血。酒大黄善清上焦血分热毒。用于目赤咽肿，齿龈肿痛。熟大黄泻下力缓，泻火解毒。用于火毒疮疡。大黄炭凉血化瘀止血。用于血热有瘀出血症。
人参：性味与归经：甘、微苦，平。归脾、肺、心经。功能与主治：大补元气，复脉固脱，补脾益肺，生津，安神。用于体虚欲脱，肢冷脉微，脾虚食少，肺虚喘咳，津伤口渴，内热消渴，久病虚羸，惊悸失眠，阳痿宫冷；心力衰竭，心原性休克。
牡丹皮：性味与归经：苦、辛，微寒。归心、肝、肾经。功能与主治：清热凉血，活血化瘀。用于温毒发斑，吐血衄血，夜热早凉，无汗骨蒸，经闭痛经，痈肿疮毒，跌扑伤痛。
天花粉：性味与归经：甘、微苦，微寒。归肺、胃经。功能与主治：清热生津，消肿排脓。用于热病烦渴，肺热燥咳，内热消渴，疮疡肿毒。
土鳖虫：性味与归经：咸，寒；有小毒。归肝经。功能与主治：破瘀血，续筋骨。用于筋骨折伤，瘀血经闭,癥瘕痞块。
发明内容
本发明旨在提供一种治疗白塞病的中药及其制备方法，通过选择合适的药材及其配比，以达到安全有效治愈白塞病的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗白塞病的中药，其特征在于：它是由以下重量份的药材组成：甘草50g、白花蛇舌草50g、女贞子20g、天名精30g、白菊花根30g、芦根30g、败酱草30g、大黄6g、三棱20g、桃仁5g、人参30g、牡丹皮15g、天花粉20g、土鳖虫20g。
本发明具体使用方法：正常成年患者每日需服用：使用“甘草50g、白花蛇舌草50g、女贞子20g、天名精30g、白菊花根30g、芦根30g、败酱草30g、大黄6g、三棱20g、桃仁5g、人参30g、牡丹皮15g、天花粉20g、土鳖虫20g。”将上述药材混合水煎3遍，共约1000毫升，每日一剂，分早中晚口服。
下面结合中医理论说明本发明的有益效果：
发明人认为：正气存内，邪不可干，邪之所凑，其气必虚。本病辩证复杂，初为表症，外邪侵入皮肤、经络渐入半表半里，耗其心、肺胃、肝、肾经、等脏腑。后为里症，心火上炎，五内瘀积，气血两亏，反制口、阴部溃疡久治不愈。发明人认为应以内向外疏导，兼顾各归经用药，通其蕴毒，滋其元气，清其脏腑。
辩证如下：甘草、桃仁归心经，用于清热解毒破血行瘀。天名精、芦根、天花粉归肺经，用于清肺热破瘀。土鳖虫、三棱、女贞子、牡丹皮归肝肾经，用于清热凉血，破瘀并舒经络，滋补肝肾。大黄、白花蛇舌草、败酱草归大肠经，肺与大肠相表里，用于清热利湿，起解毒作用。白菊花根，起排毒利水作用。因有破必有立，人参用于大补元气，增加免疫力。综上因此能够有效治疗白塞病。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
2005年7月-2012年9月间，发明人在烟台毓璜顶医院共收集130例白塞病的病房及门诊患者，其中男69例，女61例，年龄33-75岁，病程0.5-4年。按完全随机原则分为试验组100例、对照组30例。两组病人年龄、性别、主要症状、病程等比较均无显著差异，具有可比性。
2、试验方法
2.1治疗方法
试验组：服用本发明配方制得的制剂，每天3次，每日一剂，21天为一疗程；
对照组：服用地塞米松10mg、维生素C200mg、维生素B120mg，一天3次，21天为一疗程。
2.2观察项目：口腔及阴部溃疡的情况。
3、疗效标准
痊愈：临床症状全部消失。好转：临床症状减轻。无效：临床症状无明显好转或加重。
4、治疗结果
治疗统计结果见表1。
表1两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 不良反应例 | 总有效率(%) |
| 治疗组 | 100 | 3 | 70 | 27 | 0（0%） | 73% |
| 对照组 | 30 | 0 | 20 | 10 | 0（0%） | 66、7% |
可见，本发明优选实施方式制得的药物能够安全有效治疗白塞病。
根据上述临床实验数据，结合本发明治疗白塞病的中医学机理分析和本领域背景技术，本领域技术人员容易推知，运用本发明中的药材，在其常规用量范围内取值，可以取得与本发明优选实施方式制得的药物类似的技术效果。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
一种治疗白塞病的中药，由以下药材制成：甘草50g、白花蛇舌草50g、女贞子20g、天名精30g、白菊花根30g、芦根30g、败酱草30g、大黄6g、三棱20g、桃仁5g、人参30g、牡丹皮15g、天花粉20g、土鳖虫20g。
所述中药的制备方法为：将上述药材混合水煎3遍，共约1000毫升，每日一剂，分早中晚口服。三周为一疗程。
Claims (1)
1.一种治疗白塞病的中药，其特征在于：它是由以下重量的药材组成：甘草50g、白花蛇舌草50g、女贞子20g、天名精30g、白菊花根30g、芦根30g、败酱草30g、大黄6g、三棱20g、桃仁5g、人参30g、牡丹皮15g、天花粉20g、土鳖虫20g。
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| CN1485083A (zh) * | 2003-06-13 | 2004-03-31 | 许新琳 | 甲状腺癌瘤淋巴结胶囊 |
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