CN103432332B

CN103432332B - Traditional Chinese medicine smoking lotion for treating rheumatoid arthritis

Info

Publication number: CN103432332B
Application number: CN201310356200.6A
Authority: CN
Inventors: 李桂荣; 徐玉香
Original assignee: Individual
Current assignee: Li Guirong
Priority date: 2013-08-10
Filing date: 2013-08-10
Publication date: 2015-04-29
Anticipated expiration: 2033-08-10
Also published as: CN103432332A

Abstract

The invention discloses a traditional Chinese medicine smoking lotion for treating rheumatoid arthritis. According to traditional Chinese medical science, the rheumatoid arthritis belongs to the scope of 'arthralgia', the primary asthenia is debility in vital energy and blood, yin and yang as well as viscera, the secondary sthenia syndrome is about receiving coldness, dampness and heat externally, and generating phlegm and extravasated blood internally. The traditional Chinese medicine smoking lotion is prepared from the following components: Cantonese speranskia, littleleaf indianmulberry herb, subcalvous yam roots, Chinese holly roots, radix achyranthis bidentatae, marsdenia longipes, common exbucklandia stem, acuteleaf caper roots and teasel root. According to the clinical observation, the total effective rate reaches 96.2%, the efficacy is obviously better than that of a matched group, the side effect is small and the therapy is convenient.

Description

A kind of Chinese medicine fuming-lotion for the treatment of rheumatoid arthritis

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine fuming-lotion for the treatment of rheumatoid arthritis.

Background technology

Rheumatoid arthritis is for main clinical manifestation with chronic progressive external symmetry arthralgia, formed with the synovial membrane inflammation in joint, cell invasion, synovial membrane and ossa articularia pannus, finally cause articulation structure to destroy, cause joint function disturbance to be the common autoimmune disease of one of main pathological change.Rheumatoid arthritis is a kind of chronic disease, and touching difficulty more, there is no the medicine of radical cure primary disease at present, disability rate is very high, has a strong impact on the quality of life of patient, brings larger burden to society and family, therefore most of mental pressure is comparatively large, produces frightened, lose the confidence to treatment to disease.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine fuming-lotion for the treatment of rheumatoid arthritis.Rheumatoid arthritis belongs to the traditional Chinese medical science " arthromyodynia " category, and deficiency in origin is QI and blood, negative and positive, internal organs loss, and mark is real is damp and hot heresy of having a cold outward, the turbid congestion of interior raw expectorant.Boreal climate is cold, and the heresy of rheumatism is many from cold transformation, and BI-syndrome caused mainly by pathogenic cold being called painful BI, cold stagnates, and QI and blood is obstructed, stagnation of QI and blood may bring about pain.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine fuming-lotion of this treatment rheumatoid arthritis is made up of the Chinese medicine of following weight portion: Herba speranskiae cantonensis 15-20 part, Herba Morindae Parvifoliae 25-30 part, Radix dioscoreae subcalvae 15-18 part, Radix Ilicis Cornutae 18-25 part, Radix Achyranthis Bidentatae 15-17 part, Radix Marsdeniae Longipedis 10-14 part, Caulis Exbucklandiae Populneae 9-12 part, Radix Capparis Membranaceae 13-16 part, Radix Dipsaci 11-17 part.

Preferably, Herba speranskiae cantonensis 18 parts, Herba Morindae Parvifoliae 27 parts, Radix dioscoreae subcalvae 17 parts, Radix Ilicis Cornutae 22 parts, Radix Achyranthis Bidentatae 16 parts, Radix Marsdeniae Longipedis 12 parts, Caulis Exbucklandiae Populneae 11 parts, Radix Capparis Membranaceae 15 parts, Radix Dipsaci 14 parts.

Above-mentioned Chinese medicine is put into 2800-3200mL water by preparation method, first soaks 30min, boils, for subsequent use after changing 20min at a simmer.

Fang Zhong: Herba speranskiae cantonensis, Herba Morindae Parvifoliae expelling wind and removing dampness, the meridian dredging, disappear hard block, promoting blood circulation and hemostasis, heat-clearing and toxic substances removing, eliminating stasis to stop pain; Radix dioscoreae subcalvae, Radix Ilicis Cornutae, Radix Achyranthis Bidentatae invigorating the spleen to clear away damp pathogen, tonifying the lung kidney, fresh breeze heat, promoting blood circulation to restore menstrual flow, strong waist knee joint, relieving stranguria by diuresis; Radix Marsdeniae Longipedis, Caulis Exbucklandiae Populneae relaxing muscles and tendons to promote blood circulation, activating collaterals to relieve pain; Radix Capparis Membranaceae, Radix Dipsaci removing blood stasis dissipating blood stasis, reducing swelling and alleviating pain, relaxing muscles and tendons and activating QI and blood in the collateral, invigorating the liver and kidney, bone and muscle strengthening.

Clinical data

1, all cases of physical data are all selected from my institute and are in hospital and outpatient service patient with rheumatoid arthritis for 2007 ~ 2011 years.160 routine cases are divided into two groups at random.Treatment group 80 example, wherein male 28 example, women 52 example, 43.2 years old mean age, average course of disease 5.80, rheumatoid factor (RF) positive 64 example; Matched group 80 example, male 30 example, women 50 example, 42.8 years old mean age, average course of disease 6.0 years, rheumatoid factor (RF) positive 65 example.Two groups in sex, age, the course of disease, through statistical procedures difference, there are no significant (P > 0.05), has comparability.

2, diagnostic criteria 1. main clinical manifestation: the tract pain such as joint, skin, muscles and bones or swelling morning stiff, numbness weighs, joint stuffiness, even joint swelling deformation, tetanicly not stretch, amyotrophy etc.; 2. characteristics of incidence: how relevant with climate change; 3. sex, Age Characteristics: be apt to occur in person between twenty and fifty, female is more than man; 4. physico-chemical examination: rheumatoid factor positive or erythrocyte sedimentation rate speed, the visible bone erosion of x-ray.Possess above-mentioned 1., 4. two, can make a definite diagnosis in conjunction with 2. or 3. item.

3, Therapeutic Method treatment group patient uses Chinese medicine fuming-lotion of the present invention.Namely Herba speranskiae cantonensis 18g, Herba Morindae Parvifoliae 27g, Radix dioscoreae subcalvae 17g, Radix Ilicis Cornutae 22g, Radix Achyranthis Bidentatae 16g, Radix Marsdeniae Longipedis 12g, Caulis Exbucklandiae Populneae 11g, Radix Capparis Membranaceae 15g, Radix Dipsaci 14g is taken, above-mentioned Chinese medicine is put into 3000mL water, first soak 30min, boil, for subsequent use after changing 20min at a simmer.Fumigation and wash method method: treat that water temperature drops to preference temperature, puts suffering limb fumigation and wash method above Chinese medicine fuming-lotion, namely with medicament drip washing or embathe affected part, each 30min, once a day; Matched group gives meloxicam 7.5mg/d, adds with methotrexate 10mg/ week, two groups equal 20 days for being 1 course for the treatment of.

4, criterion of therapeutical effect is cured: arthralgia, swelling disappear (index reduces >=90%), and movable function is normal, and lab testing is normal; Effective: arthralgia, swelling alleviate (index reduces 60% ~ 89%), and movable function takes a turn for the better, and lab testing take a favorable turn; Take a turn for the better: arthralgia, swelling alleviate to some extent (index reduces 31% ~ 59%), and movable function takes a turn for the better, and lab testing makes moderate progress; Invalid: arthralgia, swelling (index reduces≤30%) symptom and lab testing are without improvement.

5, therapeutic outcome two groups treats comparitive study after two courses for the treatment of, treatment group 80 example, wherein cures 58 examples (72.5), effective 13 examples (16.3), 6 examples that take a turn for the better (7.5), invalid 3 examples (3.8) total effective rate 96.2%; Matched group 80 example, wherein cures 23 examples (28.8), effective 17 examples (21.3), 24 examples that take a turn for the better (30.0), invalid 16 examples (20.0), total effective rate 80.0%.Two groups are compared, and treatment group cure rate, total effective rate, be obviously better than matched group, and P < 0.05 has comparability.

6, untoward reaction treatment group has 3 examples to occur anorexia, dyspepsia, occurs, adverse reaction rate 3.8% without transaminase and leukopenia; And matched group has 23 examples to occur anorexia, abdominal distention, stomachache, transaminase raises, leukopenia, adverse reaction rate 28.8%.Illustrate that treatment group safety is obviously better than matched group.

6, model case patient, man, 29 years old, on June 5th, 2006 went to a doctor.Private prosecution before 1 year summer sleep on concrete floor, waking up namely, the two lower limb of sense are uncomfortable, engender that knee joint is ached, swelling, joint stuffiness, pain very then can not be walked so far.Look into the obvious enlargement of patient's knee joint, touch sombre, pale tongue, tongue is greasy in vain, soft and thready pulse.Use Chinese medicine fuming-lotion prescription of the present invention: Herba speranskiae cantonensis 18g, Herba Morindae Parvifoliae 27g, Radix dioscoreae subcalvae 17g, Radix Ilicis Cornutae 22g, Radix Achyranthis Bidentatae 16g, Radix Marsdeniae Longipedis 12g, Caulis Exbucklandiae Populneae 11g, Radix Capparis Membranaceae 15g, Radix Dipsaci 14g, make fumigation and washing agent, after fumigation and wash method 3d, swelling and pain obviously alleviate, feel joint after 7d easily as usual, continue with 3d and heal.Follow up a case by regular visits to and have no recurrence in 2 years.

Detailed description of the invention

Embodiment one: take Herba speranskiae cantonensis 18g, Herba Morindae Parvifoliae 27g, Radix dioscoreae subcalvae 17g, Radix Ilicis Cornutae 22g, Radix Achyranthis Bidentatae 16g, Radix Marsdeniae Longipedis 12g, Caulis Exbucklandiae Populneae 11g, Radix Capparis Membranaceae 15g, Radix Dipsaci 14g, 3000mL water put into by above-mentioned Chinese medicine, first soak 30min, boil, change 20min at a simmer.

Embodiment two: take Herba speranskiae cantonensis 20g, Herba Morindae Parvifoliae 30g, Radix dioscoreae subcalvae 15g, Radix Ilicis Cornutae 25g, Radix Achyranthis Bidentatae 15g, Radix Marsdeniae Longipedis 10g, Caulis Exbucklandiae Populneae 9g, Radix Capparis Membranaceae 13g, Radix Dipsaci 17g, 3200mL water put into by above-mentioned Chinese medicine, first soak 30min, boil, change 20min at a simmer.

Embodiment three: take Herba speranskiae cantonensis 15g, Herba Morindae Parvifoliae 25g, Radix dioscoreae subcalvae 18g, Radix Ilicis Cornutae 18g, Radix Achyranthis Bidentatae 17g, Radix Marsdeniae Longipedis 14g, Caulis Exbucklandiae Populneae 12g, Radix Capparis Membranaceae 16g, Radix Dipsaci 11g, 2800mL water put into by above-mentioned Chinese medicine, first soak 30min, boil, change 20min at a simmer.

Claims

1. treat the Chinese medicine fuming-lotion of rheumatoid arthritis for one kind, it is characterized in that this Chinese medicine fuming-lotion is made up of the Chinese medicine of following weight: Herba speranskiae cantonensis 18g, Herba Morindae Parvifoliae 27g, Radix dioscoreae subcalvae 17g, Radix Ilicis Cornutae 22g, Radix Achyranthis Bidentatae 16g, Radix Marsdeniae Longipedis 12g, Caulis Exbucklandiae Populneae 11g, Radix Capparis Membranaceae 15g, Radix Dipsaci 14g, 3000mL water put into by above-mentioned Chinese medicine, first soak 30min, boil, change 20min at a simmer.