CN103426712A - Aerosol mass spectrometer with particle size selection - Google Patents
Aerosol mass spectrometer with particle size selection Download PDFInfo
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- CN103426712A CN103426712A CN2012101665893A CN201210166589A CN103426712A CN 103426712 A CN103426712 A CN 103426712A CN 2012101665893 A CN2012101665893 A CN 2012101665893A CN 201210166589 A CN201210166589 A CN 201210166589A CN 103426712 A CN103426712 A CN 103426712A
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Abstract
The invention applies for an aerosol mass spectrometer with particle size selection, wherein the aerosol mass spectrometer can simultaneously select the particle size, the concentration and the chemical component of the atmospheric aerosol. The aerosol mass spectrometer uses a sampling hole with the diameter of 100 micrometers to carry out direct sampling on an aerosol in a natural environment; aerosol particles are focused into a particle beam flow with the 0.5-milimeter diameter by a pneumatic focusing lens; the aerosol particles are selected by a particle size selector that is formed by three coaxial rotating plates with slits, wherein the rotating plates of the particle size selector are driven by a synchronous motor and the frequency of the synchronous motor power supply can be adjusted continuously; an aerosol particle that is selected by the particle size selector is gasified by a gasifier with the high temperature from 600 to 700 degrees; gas after gasification is ionized by an electron collision ionizer; a generated ion is detected by a W type reflection type mass spectrum apparatus so as to obtain the mass spectrum of the aerosol. Therefore, information including the particle size, the concentration and the chemical composition of the organic aerosol can be obtained by analyzing the sampling rate, the frequency of the synchronous motor power supply and the obtained mass spectrum.
Description
Affiliated technical field
The present invention relates to a kind of particle diameter and select aerosol mass spectrometer, particle diameter, concentration and chemical composition that it can on-line measurement atmospheric aerosol particle.
Background technology
Aerosol Pollution has become China's big and medium-sized cities air pollution principal mode in recent years, and it is healthy that Aerosol Pollution not only endangers civic, and the gray haze phenomenon again and again occurred also affects all many-sides such as city image, traffic.Along with economic growth, living standards of the people improve day by day, and the monitoring of Aerosol Pollution and improvement have become a matter of utmost importance of urban environment.The chemical composition of atmospheric aerosol is very complicated, and it contains various trace meters, inorganic oxide, sulfate, nitrate, hydrocarbon and oxygen-containing organic compound etc.The conventional aerosol component analyzing method is to utilize gatherer to collect aerosol, then uses analytical instrument (as HPLC/MS or GC/MS) to go to analyze aerocolloidal chemical composition, the time (several hours to several weeks) that this process usually need to be longer.Accumulate a large amount of data although this method is aerosol research, can not obtain aerocolloidal chemical composition information over time comprehensively, can't find effective theoretical foundation for controlling aerocolloidal pollution.Simultaneously, the aerosol contaminants of different-grain diameter section is also different to the extent of injury of human body and environment.Therefore, traditional aerosol component analytical method can not meet people's demand that detection is analyzed for aerosol.
The aerosol mass spectrometry technology maturation is in last century end, and the main inventor of two main technology paths is the Kimberly A.Prather professor in branch school, Santiago, University of California and John doctor Jayne of Aerodyne company.Kimberly professor A.Prather has invented the aerosol mass spectrometer based on laser desorption ionization technology, it utilizes two bundle continuous lasers to obtain aerosol particle diameter information, an additional bundle of pulsed laser (wavelength 266 nanometers) comes boil-off gas colloidal sol ionization to produce ion, then detect ion signal with reflective mass spectrometer, this instrument is the blank of Technical Sourcing Internation's 3800 aerosol time-of-flight mass spectrometers; The human hairs such as John doctor T.Jayne understand the aerosol mass spectrometer based on hot gas-electron impact ionization technology, it is Aerodyne company aerosol mass spectrometer, it utilizes the high speed rotating plate of similar chopper to obtain aerosol particle diameter information, then adds quadrupole mass spectrometer by hot surface boil-off gas colloidal sol by electron impact ionization and detect aerocolloidal chemical composition.The single rotating disk of this instrument utilization is resolved grain diameter and mass spectral:mass spectrographic corresponding relation in conjunction with the method for mass spectrum data matrix, and structure is comparatively simple, but data are stored with matrix form, data volume is very large, resolve difficulty, staff training needs for a long time, and data analysis also needs the plenty of time.At present, use TSI and Aerodyne aerosol time-of-flight mass spectrometry instrument R&D institution or colleges and universities that family more than 100 is approximately arranged altogether both at home and abroad.Also have in addition the various aerosol mass spectrometers by scientific research personnel oneself assembling quite a lot, as adopted vacuum-ultraviolet light, make the aerosol mass spectrometer etc. of ionization source.
The aerosol mass spectrometer of different technologies route has different characteristics, and the aerosol mass spectrometer based on the electron impact ionization technology can be analyzed the inorganic and organic substances of the overwhelming majority, quantitative analysis preferably, but the material of the infusibility that can not gasify is as silicon dioxide etc.All substances can be resolved/ionize to aerosol mass spectrometer based on laser desorption ionization technology, can be for studying the refractory particle thing such as sand and dust, and sensitivity is higher, in analyzing aerosol, on metallic element, has a clear superiority in, and its shortcoming is the poor-performing of quantitative measurment.Aerosol mass spectrometer based on these two kinds of technology all has certain commercial market at present.
Summary of the invention
In order to overcome the deficiency of existing aerosol mass spectrometer on grain diameter is measured, the present invention has integrated the advanced technology in multiple aerosol mass spectrometry research, and a kind of new aerosol mass spectrometer is provided.This aerosol mass spectrometer has adopted micropore sample introduction and pneumatic condenser lens particle focusing technology, rotating disk particle diameter selector technology, high-temperature gasification technology, electron collision technology and W type dual reflective ion detection technology.
The technical scheme that patent of the present invention adopts is: 1. aerosol particle directly sucks instrument by the micropore of diameter 100 μ m under atmospheric environment; 2. the aerosol particle that is inhaled into instrument incides vacuum chamber by pneumatic condenser lens acceleration with after focusing on the particle line that forms 0.5 millimeter of a diameter; 3. grain flow and rotating disk particle diameter selector meet subsequently, and due to the restriction of distance and angle between rotary speed and rotating disk, each only particle in certain particle size range can be through the slit of particle diameter selector; 4. rotating disk particle diameter selector is by synchronous machine drives; 5. the rotating speed of synchronous machine is by the FREQUENCY CONTROL of synchronous machine power supply; 6. the frequency of synchronous machine power supply is adjustable continuously; 7. the aerosol particle that selectivity is passed through is vaporized after striking the high temperature surface of gasifier immediately; 8. the gas after the gasification is ionized by 70eV electron impact ionization device; 9. the ion generated is surveyed by the reflective mass spectrometric apparatus of W type; 10. the particle diameter of aerosol particle, concentration and chemical composition can be analyzed acquisition by sample rate, synchronous machine frequency and mass spectrum.
The invention has the beneficial effects as follows, to airborne aerosol Direct Sampling, realize that grain diameter is with mass spectral:mass spectrographic corresponding one by one, greatly reduce the storage capacity of data and the difficulty of analysis, improved the instrument service efficiency, reduced the instrument use cost, can detect particle diameter, concentration and the chemical composition of aerosol particle in atmosphere simultaneously, thereby effectively atmospheric aerosol be analyzed and detected.
The accompanying drawing explanation
The outside drawing that Fig. 1 is structure of the present invention, be divided into 1. electron gun chambers, 2. grain diameter measurement chamber, 3. gasification ionization chamber, four parts of the reflective mass spectrometric apparatus of 4.W type.
Fig. 2 is sectional structural map of the present invention, critical piece has: 5. thieff hatch, 6. break valve, 7. pneumatic focus lens group, 8. rotating disk, 9. particle diameter selector turntable, 10. rotating disk after the particle diameter selector before the particle diameter selector, 11. motor-driven combination, 12. small synchronous motor, 13. electron impact ionization devices, 14. high temperature gasifiers, 15. ion migration battery lead plate combination, 16. the combination of Ion Extraction accelerating electrode plate, 17. high electric field strength ion mirror, 18. low electric field strength ion mirror, 19. MICROCHANNEL PLATE ION DETECTORS, 20,21,22. is molecular pump.
Embodiment
Particle diameter selects the main part of aerosol mass spectrometer by electron gun chamber (1), and grain diameter measurement chamber (2), (4) four parts of gasification ionization chamber (3) and the reflective matter device of W type form.Embodiment is: one, aerosol is directly sucked from atmosphere by the thieff hatch (5) of 100 microns of diameters; Two, whether break valve (6) can control sampling; Three, aerosol particle enters pneumatic focus lens group (7) subsequently, pneumatic focus lens group is comprised of the disk in a series of 2-5mm aperture, and in pneumatic focus lens group, aerosol particle is accelerated and focuses on the aerosol particle stream that forms 0.5 millimeter of diameter; Four, aerosol particle enters grain diameter measurement chamber (2) from the aperture between electron gun chamber (1) and grain diameter measurement chamber (2), and the particle diameter selector in the grain diameter measurement chamber meets, the particle diameter selector is comprised of the rotating disk with slit (8,9,10), motor-driven combination (11) and a small synchronous motor (12), due to the restriction of distance and angle between rotary speed and rotating disk, each only particle in certain particle size range can be through the slit of particle diameter selector; Five, the rotating speed of synchronous machine is by the FREQUENCY CONTROL of synchronous machine power supply, and the frequency of synchronous machine power supply is adjustable continuously, and rotating speed and the grain diameter of synchronous machine have one-to-one relationship; Six, the aerosol particle that selectivity is passed through enters gasification ionization chamber (3) after passing the aperture between grain diameter measurement chamber (2) and gasification ionization chamber (3), aerosol particle is got on high temperature gasifier (13) and is vaporized subsequently, and the gas after gasification is ionized by electron collision device (14) immediately; Seven, the ion formed is detected by the reflective mass spectrometric apparatus of W type (4), obtains aerocolloidal mass spectrum, after processing and analyzing, just can obtain the information of particle diameter, concentration and the chemical composition of Organic aerosol particle.
Claims (10)
1. particle diameter selects aerosol mass spectrometer to be comprised of electron gun chamber, grain diameter measurement chamber, gasification ionization chamber and the reflective mass spectrometric apparatus of W type.It is characterized in that the electron gun chamber, grain diameter measurement chamber, gasification ionization chamber are connected successively with the reflective mass spectrometric apparatus of W type, between between electron gun chamber and grain diameter measurement chamber and grain diameter measurement chamber and gasification ionization chamber, have aperture to be connected, the reflective mass spectrometric apparatus of W type and electron gun chamber, grain diameter measurement chamber, the ionization chamber that gasifies are parallel.In the electron gun chamber, the pneumatic focus lens group of aerosol is installed, the particle diameter selector is housed in the grain diameter measurement chamber, in the gasification ionization chamber, high temperature gasifier and electron impact ionization device are housed.The electron gun chamber, the grain diameter measurement chamber, all be connected with molecular pump on gasification ionization chamber and the reflective mass spectrometric apparatus of W type, and molecular pump is connected with membrane pump.
2. particle diameter according to claim 1 is selected aerosol mass spectrometer, and it is characterized in that: atmospheric aerosol is not treated, and directly the thieff hatch by 100 microns of diameters enters into the electron gun chamber.
3. particle diameter according to claim 1 is selected aerosol mass spectrometer, it is characterized in that: in Sample Room, by pneumatic focus lens group, aerosol particle is focused on.
4. particle diameter according to claim 1 is selected aerosol mass spectrometer, it is characterized in that: in the grain diameter measurement chamber, the particle diameter selector is installed.
5. particle diameter according to claim 1 is selected aerosol mass spectrometer, it is characterized in that: three coaxial turntables with slit that the particle diameter selector is driven by small synchronous motor form.
6. particle diameter according to claim 1 is selected aerosol mass spectrometer, it is characterized in that: the supply frequency that small synchronous motor drives is continuously adjustable.
7. particle diameter according to claim 1 is selected aerosol mass spectrometer, it is characterized in that: in the gasification ionization chamber, high temperature gasifier is installed.
8. particle diameter according to claim 1 is selected aerosol mass spectrometer, it is characterized in that: in the gasification ionization chamber, the electron impact ionization device is installed.
9. particle diameter according to claim 1 is selected aerosol mass spectrometer, it is characterized in that: ion is surveyed by the reflective mass spectrometric apparatus of W type.
10. particle diameter according to claim 1 is selected aerosol mass spectrometer, it is characterized in that: the reflective mass spectrometric apparatus of W type and electron gun chamber, grain diameter measurement chamber, the ionization chamber that gasifies are parallel.
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104777258A (en) * | 2014-01-12 | 2015-07-15 | 中国科学院生态环境研究中心 | Vacuum ultraviolet light longitudinal ionization volatile organic matter W type mass spectrometer |
| CN107946165A (en) * | 2017-11-29 | 2018-04-20 | 中国科学院合肥物质科学研究院 | A kind of aerosol mass spectrometer for measuring nanoparticles chemical constituent |
| CN109187288A (en) * | 2018-08-31 | 2019-01-11 | 南京天博环境检测技术有限公司 | A kind of detection of atmosphere Organic aerosol and Source Apportionment |
| CN109427535A (en) * | 2017-08-31 | 2019-03-05 | 天源华威集团有限公司 | Aerosol mass spectrometer |
| CN110706996A (en) * | 2015-03-06 | 2020-01-17 | 英国质谱公司 | Impact surface for improved ionization |
| US11239066B2 (en) | 2015-03-06 | 2022-02-01 | Micromass Uk Limited | Cell population analysis |
| US11264223B2 (en) | 2015-03-06 | 2022-03-01 | Micromass Uk Limited | Rapid evaporative ionisation mass spectrometry (“REIMS”) and desorption electrospray ionisation mass spectrometry (“DESI-MS”) analysis of swabs and biopsy samples |
| US11270876B2 (en) | 2015-03-06 | 2022-03-08 | Micromass Uk Limited | Ionisation of gaseous samples |
| US11282688B2 (en) | 2015-03-06 | 2022-03-22 | Micromass Uk Limited | Spectrometric analysis of microbes |
| US11289320B2 (en) | 2015-03-06 | 2022-03-29 | Micromass Uk Limited | Tissue analysis by mass spectrometry or ion mobility spectrometry |
| US11367605B2 (en) | 2015-03-06 | 2022-06-21 | Micromass Uk Limited | Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue |
| US11454611B2 (en) | 2016-04-14 | 2022-09-27 | Micromass Uk Limited | Spectrometric analysis of plants |
| US11515136B2 (en) | 2015-03-06 | 2022-11-29 | Micromass Uk Limited | Spectrometric analysis |
| CN117147670A (en) * | 2023-10-26 | 2023-12-01 | 广州源古纪科技有限公司 | VOCs detection method, system and equipment |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5621208A (en) * | 1994-05-24 | 1997-04-15 | Commissariat A L'energie Atomique | Particle, particularly submicron particle spectrometer |
| US6259101B1 (en) * | 1997-09-23 | 2001-07-10 | University Of Delaware | Method and instruments for the on-line detection, sizing or analysis of aerosol particles |
| JP2001208673A (en) * | 2000-01-28 | 2001-08-03 | Inst Of Physical & Chemical Res | Fine particle measuring device, fine particle collecting device, and fine particle analyzing device |
| CN101149326A (en) * | 2006-09-21 | 2008-03-26 | 中国科学院生态环境研究中心 | Vacuum ultraviolet ionized aerosol mass spectrometer |
| CN102262039A (en) * | 2011-04-27 | 2011-11-30 | 上海大学 | Method and device for detecting indoor heavy metal pollution by using single particle aerosol mass spectrometer (SPAMS) |
-
2012
- 2012-05-25 CN CN2012101665893A patent/CN103426712A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5621208A (en) * | 1994-05-24 | 1997-04-15 | Commissariat A L'energie Atomique | Particle, particularly submicron particle spectrometer |
| US6259101B1 (en) * | 1997-09-23 | 2001-07-10 | University Of Delaware | Method and instruments for the on-line detection, sizing or analysis of aerosol particles |
| JP2001208673A (en) * | 2000-01-28 | 2001-08-03 | Inst Of Physical & Chemical Res | Fine particle measuring device, fine particle collecting device, and fine particle analyzing device |
| CN101149326A (en) * | 2006-09-21 | 2008-03-26 | 中国科学院生态环境研究中心 | Vacuum ultraviolet ionized aerosol mass spectrometer |
| CN102262039A (en) * | 2011-04-27 | 2011-11-30 | 上海大学 | Method and device for detecting indoor heavy metal pollution by using single particle aerosol mass spectrometer (SPAMS) |
Non-Patent Citations (1)
| Title |
|---|
| 高绍凯等: "气溶胶质谱仪在研究有机气溶胶环境微界面过程中的应用", 《环境科学学报》 * |
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104777258A (en) * | 2014-01-12 | 2015-07-15 | 中国科学院生态环境研究中心 | Vacuum ultraviolet light longitudinal ionization volatile organic matter W type mass spectrometer |
| US11282688B2 (en) | 2015-03-06 | 2022-03-22 | Micromass Uk Limited | Spectrometric analysis of microbes |
| US11264223B2 (en) | 2015-03-06 | 2022-03-01 | Micromass Uk Limited | Rapid evaporative ionisation mass spectrometry (“REIMS”) and desorption electrospray ionisation mass spectrometry (“DESI-MS”) analysis of swabs and biopsy samples |
| US11270876B2 (en) | 2015-03-06 | 2022-03-08 | Micromass Uk Limited | Ionisation of gaseous samples |
| US11367605B2 (en) | 2015-03-06 | 2022-06-21 | Micromass Uk Limited | Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue |
| CN110706996A (en) * | 2015-03-06 | 2020-01-17 | 英国质谱公司 | Impact surface for improved ionization |
| US11367606B2 (en) | 2015-03-06 | 2022-06-21 | Micromass Uk Limited | Rapid evaporative ionisation mass spectrometry (“REIMS”) and desorption electrospray ionisation mass spectrometry (“DESI-MS”) analysis of swabs and biopsy samples |
| US11239066B2 (en) | 2015-03-06 | 2022-02-01 | Micromass Uk Limited | Cell population analysis |
| US11515136B2 (en) | 2015-03-06 | 2022-11-29 | Micromass Uk Limited | Spectrometric analysis |
| US11289320B2 (en) | 2015-03-06 | 2022-03-29 | Micromass Uk Limited | Tissue analysis by mass spectrometry or ion mobility spectrometry |
| CN110706996B (en) * | 2015-03-06 | 2023-08-11 | 英国质谱公司 | Impact surface for improved ionization |
| US11342170B2 (en) | 2015-03-06 | 2022-05-24 | Micromass Uk Limited | Collision surface for improved ionisation |
| US11454611B2 (en) | 2016-04-14 | 2022-09-27 | Micromass Uk Limited | Spectrometric analysis of plants |
| CN109427535A (en) * | 2017-08-31 | 2019-03-05 | 天源华威集团有限公司 | Aerosol mass spectrometer |
| CN107946165A (en) * | 2017-11-29 | 2018-04-20 | 中国科学院合肥物质科学研究院 | A kind of aerosol mass spectrometer for measuring nanoparticles chemical constituent |
| CN107946165B (en) * | 2017-11-29 | 2019-09-24 | 中国科学院合肥物质科学研究院 | A kind of aerosol mass spectrometer measuring nanoparticles chemical constituent |
| CN109187288B (en) * | 2018-08-31 | 2021-04-23 | 南京天博环境检测技术有限公司 | Atmospheric organic aerosol detection and source analysis method |
| CN109187288A (en) * | 2018-08-31 | 2019-01-11 | 南京天博环境检测技术有限公司 | A kind of detection of atmosphere Organic aerosol and Source Apportionment |
| CN117147670B (en) * | 2023-10-26 | 2023-12-29 | 广州源古纪科技有限公司 | VOCs detection method, system and equipment |
| CN117147670A (en) * | 2023-10-26 | 2023-12-01 | 广州源古纪科技有限公司 | VOCs detection method, system and equipment |
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