CN103416419B - A kind of Pesticidal combination containing CGA 183893 Yu anabasine - Google Patents
A kind of Pesticidal combination containing CGA 183893 Yu anabasine Download PDFInfo
- Publication number
- CN103416419B CN103416419B CN201210151878.6A CN201210151878A CN103416419B CN 103416419 B CN103416419 B CN 103416419B CN 201210151878 A CN201210151878 A CN 201210151878A CN 103416419 B CN103416419 B CN 103416419B
- Authority
- CN
- China
- Prior art keywords
- cga
- active component
- agent
- insect
- active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000000361 pesticidal effect Effects 0.000 title claims abstract description 15
- MTXSIJUGVMTTMU-JTQLQIEISA-N (S)-anabasine Chemical compound N1CCCC[C@H]1C1=CC=CN=C1 MTXSIJUGVMTTMU-JTQLQIEISA-N 0.000 title claims abstract description 9
- 229930014345 anabasine Natural products 0.000 title claims abstract description 9
- 239000000203 mixture Substances 0.000 claims abstract description 36
- NWWZPOKUUAIXIW-DHZHZOJOSA-N (E)-thiamethoxam Chemical compound [O-][N+](=O)/N=C/1N(C)COCN\1CC1=CN=C(Cl)S1 NWWZPOKUUAIXIW-DHZHZOJOSA-N 0.000 claims abstract description 35
- 241000238631 Hexapoda Species 0.000 claims abstract description 30
- 239000000375 suspending agent Substances 0.000 claims description 29
- 239000004563 wettable powder Substances 0.000 claims description 24
- 241000209094 Oryza Species 0.000 claims description 15
- 235000007164 Oryza sativa Nutrition 0.000 claims description 15
- 241001414989 Thysanoptera Species 0.000 claims description 15
- 239000003795 chemical substances by application Substances 0.000 claims description 15
- 235000009566 rice Nutrition 0.000 claims description 15
- 241001124076 Aphididae Species 0.000 claims description 14
- 239000003094 microcapsule Substances 0.000 claims description 14
- 241001414720 Cicadellidae Species 0.000 claims description 12
- 244000269722 Thea sinensis Species 0.000 claims description 12
- 241000018137 Trialeurodes vaporariorum Species 0.000 claims description 12
- 239000000839 emulsion Substances 0.000 claims description 12
- 241000254127 Bemisia tabaci Species 0.000 claims description 11
- 241000426497 Chilo suppressalis Species 0.000 claims description 8
- 241001498622 Cixius wagneri Species 0.000 claims description 8
- 241000008892 Cnaphalocrocis patnalis Species 0.000 claims description 8
- 229920000742 Cotton Polymers 0.000 claims description 8
- 241000086608 Empoasca vitis Species 0.000 claims description 8
- 241000255967 Helicoverpa zea Species 0.000 claims description 8
- 241000258937 Hemiptera Species 0.000 claims description 8
- 241000500437 Plutella xylostella Species 0.000 claims description 8
- 241001249129 Scirpophaga incertulas Species 0.000 claims description 8
- 241000256247 Spodoptera exigua Species 0.000 claims description 8
- 239000000725 suspension Substances 0.000 claims description 7
- 239000004530 micro-emulsion Substances 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 239000005888 Clothianidin Substances 0.000 abstract description 36
- 239000005940 Thiacloprid Substances 0.000 abstract description 36
- PGOOBECODWQEAB-UHFFFAOYSA-N (E)-clothianidin Chemical compound [O-][N+](=O)\N=C(/NC)NCC1=CN=C(Cl)S1 PGOOBECODWQEAB-UHFFFAOYSA-N 0.000 abstract description 35
- HOKKPVIRMVDYPB-UVTDQMKNSA-N (Z)-thiacloprid Chemical compound C1=NC(Cl)=CC=C1CN1C(=N/C#N)/SCC1 HOKKPVIRMVDYPB-UVTDQMKNSA-N 0.000 abstract description 35
- 241000607479 Yersinia pestis Species 0.000 abstract description 23
- 239000000575 pesticide Substances 0.000 abstract description 18
- 150000001875 compounds Chemical class 0.000 abstract description 6
- 238000012271 agricultural production Methods 0.000 abstract description 2
- 230000007423 decrease Effects 0.000 abstract description 2
- 230000007613 environmental effect Effects 0.000 abstract description 2
- 238000003912 environmental pollution Methods 0.000 abstract description 2
- 244000144977 poultry Species 0.000 abstract description 2
- 206010059866 Drug resistance Diseases 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 48
- 239000003814 drug Substances 0.000 description 36
- 238000013329 compounding Methods 0.000 description 27
- 230000010165 autogamy Effects 0.000 description 24
- 230000003449 preventive effect Effects 0.000 description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 17
- 239000008367 deionised water Substances 0.000 description 14
- 229910021641 deionized water Inorganic materials 0.000 description 14
- 239000002270 dispersing agent Substances 0.000 description 14
- 239000012071 phase Substances 0.000 description 14
- 239000013530 defoamer Substances 0.000 description 12
- 239000003995 emulsifying agent Substances 0.000 description 10
- 239000000080 wetting agent Substances 0.000 description 10
- 230000002528 anti-freeze Effects 0.000 description 9
- 230000000694 effects Effects 0.000 description 9
- 239000002562 thickening agent Substances 0.000 description 9
- 239000000470 constituent Substances 0.000 description 8
- 239000002904 solvent Substances 0.000 description 8
- 229940079593 drug Drugs 0.000 description 7
- 206010067482 No adverse event Diseases 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 230000002265 prevention Effects 0.000 description 6
- 206010011732 Cyst Diseases 0.000 description 5
- 239000008346 aqueous phase Substances 0.000 description 5
- 208000031513 cyst Diseases 0.000 description 5
- 229920002521 macromolecule Polymers 0.000 description 5
- 231100000820 toxicity test Toxicity 0.000 description 5
- 241001600408 Aphis gossypii Species 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 239000011230 binding agent Substances 0.000 description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 238000013401 experimental design Methods 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000003002 pH adjusting agent Substances 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 239000003381 stabilizer Substances 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
- 231100000419 toxicity Toxicity 0.000 description 4
- 241001672694 Citrus reticulata Species 0.000 description 3
- 244000141359 Malus pumila Species 0.000 description 3
- 235000011430 Malus pumila Nutrition 0.000 description 3
- 235000015103 Malus silvestris Nutrition 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 238000000498 ball milling Methods 0.000 description 3
- 239000002552 dosage form Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 238000013019 agitation Methods 0.000 description 2
- -1 alkaloid compound Chemical class 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 239000002917 insecticide Substances 0.000 description 2
- 235000021374 legumes Nutrition 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- 230000001018 virulence Effects 0.000 description 2
- PKTIFYGCWCQRSX-UHFFFAOYSA-N 4,6-diamino-2-(cyclopropylamino)pyrimidine-5-carbonitrile Chemical compound NC1=C(C#N)C(N)=NC(NC2CC2)=N1 PKTIFYGCWCQRSX-UHFFFAOYSA-N 0.000 description 1
- 241000273311 Aphis spiraecola Species 0.000 description 1
- 244000061176 Nicotiana tabacum Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 102000019315 Nicotinic acetylcholine receptors Human genes 0.000 description 1
- 108050006807 Nicotinic acetylcholine receptors Proteins 0.000 description 1
- 239000005941 Thiamethoxam Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 239000010413 mother solution Substances 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 230000019617 pupation Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of Pesticidal combination containing CGA 183893 Yu anabasine, containing active components A and the Pesticidal combination of active component B, wherein active components A is selected from CGA 183893, active component B is selected from any one compound following: Diacloden, thiacloprid, clothianidin, MTI-446, and the weight ratio of active components A and active component B is 1 80 ~ 60 1.The present composition has potentiation to the various pests of harm agricultural production, decreases pesticide usage amount, reduces pesticide residual quantity on crop, alleviate environmental pollution, and to person poultry safety, Environmental compatibility is good, and insect is not likely to produce Drug resistance.<!--1-->
Description
Technical field
The invention belongs to technical field of pesticide, relate to the application on crop pests of a kind of Pesticidal combination containing CGA 183893 and anabasine.
Background technology
CGA 183893 (dicyclanil) chemical name: 4,6-diaminourea-2-cyclopropylamino pyrimidine-5-nitriles, molecular formula: C8H10N6.CGA 183893 interference insect is peeled, and after insect generations Systemic absorption, stops larvae pupation or becomes worm.
Diacloden, thiacloprid, clothianidin, MTI-446 all belong to Novel tobacco alkaloid compound, act on the nicotinic acetylcholine receptors of insecticide, have stronger interior suction, tag and stomach poison function, are controlling sucking insects and the specific drug of chewing type insect.
But, in the real process of agricultural production, pest control is easiest to generate the problem that the generation of pest resistance to insecticide.Different cultivars composition compounds, and is to prevent and treat the method that resistant insect is the most common.Heterogeneity compounds, according to practical application effect, judge certain compounding be potentiation, add and or antagonism.In most cases, the compounding effect of pesticide is all additive effect, really have potentiation compounding seldom, especially potentiation clearly, the highest compounding the most less of co-toxicity coefficient.Study through inventor, good potentiation after finding to compound CGA 183893 with Diacloden, thiacloprid, clothianidin, MTI-446, can be produced, and the openest with the relevant report that Diacloden, thiacloprid, clothianidin, MTI-446 compound about CGA 183893.
Summary of the invention
The purpose of the present invention is to propose to a kind of there is synergistic function, use cost is low, preventive effect the is good Pesticidal combination containing CGA 183893 Yu anabasine.The Pesticidal combination that the present invention proposes contains active components A and active component B, active components A and active component B weight ratio are 1 80 ~ 60 1, described active components A is selected from CGA 183893, active component B plants selected from one of Diacloden, thiacloprid, clothianidin, MTI-446, and active components A and the preferred weight ratio of active component B are 1 60 ~ 40 1；More preferably CGA 183893 is 1 20 ~ 10 1 with the weight ratio of Diacloden, and CGA 183893 is 1 30 ~ 10 1 with the weight ratio of thiacloprid, and CGA 183893 is 1 25 ~ 10 1 with the weight ratio of clothianidin, and CGA 183893 is 1 30 ~ 20 1 with the weight ratio of MTI-446.
The described Pesticidal combination containing CGA 183893 with anabasine is used for preventing and treating the purposes of insect on fruit tree, vegetable, cereal crops, fibre crops, legume crop, ornamental plant, lawn, forest.
Described insect includes: planthopper, rice leaf roller, striped rice borer, yellow rice borer, trialeurodes vaporariorum, Bemisia tabaci, aphid, thrips, Anoplophorae seu Aprionae, scale insect, tea lesser leafhopper, bollworm, cotton boll are as, beet armyworm, rice green leafhopper, diamondback moth.
Active components A, the weight ratio of active component B are 1 80 ~ 60 1.Generally in compositions weight percentage is gross weight 0.5%～the 90% of active component, it is preferably 5%～80%.According to different preparation types, active component content scope is different.Generally, liquid preparation contains the active substance of by weight 1%～70%, preferably 5%～50%；Solid preparation contains the active substance of by weight 5%～80%, preferably 10%～80%.
The Pesticidal combination of the present invention at least contains a kind of surfactant, active component dispersion in water when being beneficial to use.Surface-active contents is the 5%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
Surfactant selected by the Pesticidal combination of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, binding agent or defoamer.According to different dosage form, preparation can also contain disintegrating agent known in those skilled in the art, antifreeze etc..
The Pesticidal combination of the present invention through dilution or directly can be used before use by user.Its preparation can be prepared by common processing method known in those skilled in the art, one or more in surfactant such as dispersant, stabilizer, wetting agent, binding agent, defoamer etc. will be added after active substance mixes with liquid flux or solid carrier.
Pesticidal combination disclosed in this invention, can be processed into acceptable dosage form on any pesticide on demand, the most more preferably dosage form is wettable powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
Compositions comprises following constituent content when making wettable powder: active components A 1% ~ 60%, active component B1% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
Compositions includes following constituent content when making water dispersible granules: active components A 1% ~ 60%, active component B1% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrating agent 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Compositions includes following constituent content when making suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickening agent 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Compositions includes following constituent content when making suspension emulsion: active components A 1% ~ 50%, active component B1% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 0 ~ 15%, thickening agent 0 ~ 2%, emulsifying agent 2% ~ 12%, antifreeze 0 ~ 8%, stabilizer 0 ~ 3%, deionized water add to 100%.
Compositions comprises following constituent content when making aqueous emulsion: active components A 1% ~ 50%, active component B1% ~ 50%, solvent 1% ~ 30%, emulsifying agent 1% ~ 15%, antifreeze 0 ~ 8%, thickening agent 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Compositions comprises following constituent content when making microemulsion: active components A 1% ~ 50%, active component B1% ~ 50%, solvent 1 ~ 30%, emulsifying agent 3% ~ 25%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, stabilizer 0 ~ 4%, deionized water supplies surplus.
Compositions includes following constituent content when making microcapsule suspending agent: active components A 1% ~ 50%, active component B1% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifying agent 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Compositions includes following constituent content when making microcapsule suspension-suspendinagent agent: active components A 1% ~ 50%, active component B1% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifying agent 1% ~ 6%, defoamer 0.01% ~ 2%, thickening agent 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%；
The wettable powder the key technical indexes of the present invention:
The water dispersible granules the key technical indexes of the present invention:
The suspending agent the key technical indexes of the present invention:
The suspension emulsion the key technical indexes of the present invention:
The aqueous emulsion the key technical indexes of the present invention:
The microemulsion the key technical indexes of the present invention:
The microcapsule suspending agent the key technical indexes of the present invention:
The microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
It is an advantage of the current invention that:
(1), after CGA 183893 compounds with Diacloden, thiacloprid, clothianidin, MTI-446, there is obvious potentiation and lasting effect；(2) planthopper on fruit tree, vegetable, cereal crops, fibre crops, legume crop, ornamental plant, lawn, forest, rice leaf roller, striped rice borer, yellow rice borer, trialeurodes vaporariorum, Bemisia tabaci, aphid, thrips, Anoplophorae seu Aprionae, scale insect, tea lesser leafhopper, bollworm, cotton boll all there is greater activity as, beet armyworm, rice green leafhopper, diamondback moth etc.；(3) decrease pesticide usage amount, reduce pesticide residual quantity on crop, alleviate environmental pollution；(4) to person poultry safety, Environmental compatibility is good；And preparation adhesion strength strengthens, resistance of rainwater washing against.
Detailed description of the invention
Below in conjunction with embodiment, further instruction of the present invention, the percentage ratio in embodiment are all weight percentage, but the invention is not limited in this.
Application Example one
Example 1 ~ 12 wettable powder
By CGA 183893, active component B, dispersant, wetting agent, filler mix homogeneously in mixed cylinder, remix uniformly after jet mill is pulverized, can be prepared by wettable powder product of the present invention, be specifically shown in Table 1.
Table 1 embodiment 1 ~ 12 each component and weight portion
Example 13 ~ 24 water dispersible granules
CGA 183893, active component B, dispersant, wetting agent, disintegrating agent, filler etc. are obtained through comminution by gas stream together the particle diameter needed, adds other auxiliary agents such as binding agent (can add and can be not added with), obtain granulation materials.Through in item is quantitatively sent into fluidized bed granulating dryer and granulation and dried, can be prepared by water dispersible granules product of the present invention, be specifically shown in Table 2.
Table 2 embodiment 13 ~ 24 each component and weight portion
Example 25 ~ 36 suspending agent
By dispersant, wetting agent, defoamer, thickening agent (can add and can be not added with), antifreeze (can add and can be not added with), through high speed shear mix homogeneously, add CGA 183893, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can be prepared by suspending agent product of the present invention, is specifically shown in Table 3.
Table 3 embodiment 25 ~ 36 each component and weight portion
Example 37 ~ 46 suspension emulsion
By dispersant, defoamer, thickening agent (can add and can be not added with), antifreeze (can add and can be not added with) through high speed shear mix homogeneously, add active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, prepare active component B suspending agent, then by CGA 183893, solvent (can add and can be not added with), emulsifying agent and the various direct emulsifying of auxiliary agent high speed agitator to suspending agent, surplus deionized water is supplied, prepare suspension emulsion product of the present invention, be specifically shown in Table 4,5.
Table 4 embodiment 37 ~ 42 each component and weight portion
Table 5 embodiment 43 ~ 46 each component and weight portion
Example 47 ~ 52 aqueous emulsion
CGA 183893, active component B, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase；Deionized water, antifreeze (can add and can be not added with), thickening agent (can add and can be not added with), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase adding oil phase, surplus deionized water is supplied；Can be prepared by aqueous emulsion product of the present invention, be specifically shown in Table 6.
Table 6 embodiment 47 ~ 52 each component and weight portion
Diacloden, thiacloprid, clothianidin, MTI-446 in table 1 ~ 6 are exchanged, novel formulation can be prepared.
Example 53 ~ 55 microemulsion
CGA 183893, active component B, solvent, emulsifying agent, antifreeze (can add and can be not added with), thickening agent, stabilizer (can add and can be not added with), defoamer are sufficiently mixed the most transparent oil phase, under agitation it is slowly added into deionized water, form Water in Oil emulsion, the most agitated heating, it is allowed to rapid phase inversion and becomes oil-in-water type, being cooled to room temperature and make up to balance, through filtering, surplus deionized water is supplied；Can be prepared by microemulsion product of the present invention, be specifically shown in Table 7.
Table 7 embodiment 53 ~ 55 each component and weight portion
Example 56,57 microcapsule suspending agent
By CGA 183893, active component B, macromolecule cyst material, solvent mixing, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined containing emulsifying agent, pH adjusting agent, dispersant aqueous phase solution in, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the present composition finely disseminated microcapsule suspending agent product.Specifically it is shown in Table 8.
Table 8 embodiment 56,57 each component and weight portion
Example 58,59 microcapsule suspension-suspendinagent agent
By CGA 183893, macromolecule cyst material, solvent mixing, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition containing emulsifying agent, pH adjusting agent aqueous phase solution in, make finely disseminated microcapsule suspending agent.By dispersant, wetting agent, defoamer, thickening agent (can add and can be not added with) through high speed shear mix homogeneously, add active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, preparing suspending agent, then joined by suspending agent in the aqueous phase solution of micro-capsule suspension, deionized water supplies surplus, make the present composition finely disseminated microcapsule suspension-suspendinagent agent product, be specifically shown in Table 9.
Table 9 embodiment 58,59 each component and weight portion
The embodiment of the present invention is the method using Toxicity Determination and field test to combine.First pass through Toxicity Determination, the co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are compounding by a certain percentage, CTC ＜ 80 is antagonism, 80≤CTC≤120 are summation action, CTC ＞ 120 is potentiation, on this basis, then carries out field test.
Test method: respectively the mother solution of each mixed agent is diluted to during test five series concentration, is respectively placed in beaker standby.Use the method that first leaching leaf is followed by worm, take out after blade of the same size not in contact with any medicament is soaked 5s in the medicinal liquid configured, naturally dry, put in insect box, then connect for examination larva, raise under the conditions of 25 DEG C, often process 3 times and repeat, often repeating examination borer population used is 50, sets blank simultaneously, checks dead borer population in 72h, calculate mortality rate and corrected mortality, try to achieve virulence regression equation and calculate LC50Value.If comparison mortality rate is more than 10%, then it is considered as invalid test.Computing formula is as follows:
Insect corrected mortality is converted into probit value (y), and concentration for the treatment of (μ g/ml) is converted into logarithm value (x), draws virulence regression equation with method of least square, and thus calculates the value of every kind of medicament, calculates co-toxicity coefficient CTC according to the abundant equation of Sun Yun.Computing formula is following (with CGA 183893 as standard agent, its toxicity index is 100):
TI × the P of theoretical toxicity index (the TTI)=CGA 183893 of MCGA 183893+TI × the P of effective active composition BEffective active composition B
In formula: M is the mixture of different ratio
PEffective active composition BFor the ratio that effective active composition B is shared in the composition
PCGA 183893For the ratio that CGA 183893 is shared in the composition
B plants selected from one of Diacloden, thiacloprid, clothianidin, MTI-446.
Application Example two:
For examination insect: mandarin tree aphid
Test medicine is provided by Shanxi Thompson Biological Technology Co., Ltd..
EXPERIMENTAL DESIGN: determine CGA 183893 and the former medicine of Diacloden and effective lethasl concentration scope of the two different ratio mixture through pilot study.
Toxicity test result
Table 10 CGA 183893 and the Thiamethoxam compound toxicity test analysis of results table to mandarin tree aphid
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| CGA 183893 | — | 2.05 | — |
| Diacloden | — | 4.12 | — |
| CGA 183893 Diacloden | 60:1 | 1.21 | 170.83 |
| CGA 183893 Diacloden | 40:1 | 1.12 | 185.31 |
| CGA 183893 Diacloden | 30:1 | 1.09 | 191.17 |
| CGA 183893 Diacloden | 10:1 | 1.00 | 214.81 |
| CGA 183893 Diacloden | 5:1 | 0.98 | 228.30 |
| CGA 183893 Diacloden | 1:1 | 1.12 | 244.46 |
| CGA 183893 Diacloden | 1:2 | 1.15 | 268.06 |
| CGA 183893 Diacloden | 1:5 | 1.43 | 246.64 |
| CGA 183893 Diacloden | 1:10 | 1.67 | 225.99 |
| CGA 183893 Diacloden | 1:20 | 1.85 | 212.51 |
| CGA 183893 Diacloden | 1:40 | 2.08 | 193.34 |
| CGA 183893 Diacloden | 1:60 | 2.21 | 183.42 |
| CGA 183893 Diacloden | 1:80 | 2.34 | 173.93 |
As shown in Table 10, CGA 183893 and Diacloden to mandarin tree aphid proportioning when 1 80 ~ 60 1, co-toxicity coefficient is all higher than 120, illustrate that both all show potentiation at mixture in the range of 1 80 ~ 60 1, when the proportioning of CGA 183893 and Diacloden is 1 20 ~ 10 1, potentiation becomes apparent from highlighting, and co-toxicity coefficient is all higher than 210.Wherein when CGA 183893 and Diacloden weight ratio are 1:2, co-toxicity coefficient is maximum, and potentiation is the most obvious.Testing discovery CGA 183893 through applicant is 10:1 with Diacloden proportioning, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:12, 1:14, 1:15, to the planthopper in various crop during 1:20, rice leaf roller, striped rice borer, yellow rice borer, trialeurodes vaporariorum, Bemisia tabaci, aphid, thrips, Anoplophorae seu Aprionae, scale insect, tea lesser leafhopper, bollworm, cotton boll as, beet armyworm, rice green leafhopper, the preventing and treating of diamondback moth has obvious potentiation potentiation obvious, co-toxicity coefficient is all higher than 120.
Application Example three
For examination insect: rice hoppers
Test medicine is provided by Shanxi Thompson Biological Technology Co., Ltd..
EXPERIMENTAL DESIGN: determine CGA 183893 and the former medicine of thiacloprid and effective lethasl concentration scope of the two different ratio mixture through pilot study.
Table 11 CGA 183893 toxicity test analysis of results table to rice hoppers compounding with thiacloprid
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| CGA 183893 | — | 1.98 | — |
| Thiacloprid | — | 5.85 | — |
| CGA 183893 thiacloprid | 60:1 | 1.22 | 164.07 |
| CGA 183893 thiacloprid | 40:1 | 1.13 | 178.09 |
| CGA 183893 thiacloprid | 30:1 | 1.05 | 192.68 |
| CGA 183893 thiacloprid | 10:1 | 0.97 | 217.18 |
| CGA 183893 thiacloprid | 5:1 | 0.97 | 229.42 |
| CGA 183893 thiacloprid | 1:1 | 1.11 | 266.53 |
| CGA 183893 thiacloprid | 1:3 | 1.41 | 278.69 |
| CGA 183893 thiacloprid | 1:5 | 1.75 | 252.13 |
| CGA 183893 thiacloprid | 1:15 | 2.23 | 233.75 |
| CGA 183893 thiacloprid | 1:30 | 2.54 | 216.63 |
| CGA 183893 thiacloprid | 1:40 | 2.87 | 194.54 |
| CGA 183893 thiacloprid | 1:60 | 3.09 | 183.42 |
| CGA 183893 thiacloprid | 1:80 | 3.34 | 171.00 |
As shown in Table 11, CGA 183893 and thiacloprid to rice hoppers proportioning when 1 80 ~ 60 1, co-toxicity coefficient is all higher than 120, illustrate that both all show potentiation at mixture in the range of 1 80 ~ 60 1, when the proportioning of CGA 183893 and thiacloprid is 1 30 ~ 10 1, potentiation becomes apparent from highlighting, and co-toxicity coefficient is all higher than 215.Wherein when CGA 183893 and thiacloprid weight ratio are 1:3, co-toxicity coefficient is maximum, and potentiation is the most obvious.Testing discovery CGA 183893 through applicant is 10:1 with thiacloprid proportioning, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:12, 1:14, 1:15, 1:20, to the planthopper in various crop during 1:30, rice leaf roller, striped rice borer, yellow rice borer, trialeurodes vaporariorum, Bemisia tabaci, aphid, thrips, Anoplophorae seu Aprionae, scale insect, tea lesser leafhopper, bollworm, cotton boll as, beet armyworm, rice green leafhopper, the preventing and treating of diamondback moth has obvious potentiation potentiation obvious, co-toxicity coefficient is all higher than 120.
Application Example four
For examination insect: Fructus Lycopersici esculenti Bemisia tabaci
Test medicine is provided by Shanxi Thompson Biological Technology Co., Ltd..
EXPERIMENTAL DESIGN: determine CGA 183893 and the former medicine of clothianidin and effective lethasl concentration scope of the two different ratio mixture through pilot study.
Table 12 CGA 183893 toxicity test analysis of results table to Fructus Lycopersici esculenti Bemisia tabaci compounding with clothianidin
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| CGA 183893 | — | 1.95 | — |
| Clothianidin | — | 4.58 | — |
| CGA 183893 clothianidin | 60:1 | 1.19 | 165.42 |
| CGA 183893 clothianidin | 40:1 | 1.11 | 178.17 |
| CGA 183893 clothianidin | 30:1 | 1.04 | 191.04 |
| CGA 183893 clothianidin | 10:1 | 0.95 | 216.57 |
| CGA 183893 clothianidin | 5:1 | 0.95 | 226.99 |
| CGA 183893 clothianidin | 1:1 | 1.11 | 246.42 |
| CGA 183893 clothianidin | 2:5 | 1.31 | 261.45 |
| CGA 183893 clothianidin | 1:5 | 1.51 | 247.63 |
| CGA 183893 clothianidin | 1:15 | 1.86 | 227.08 |
| CGA 183893 clothianidin | 1:25 | 2.05 | 214.08 |
| CGA 183893 clothianidin | 1:40 | 2.25 | 197.06 |
| CGA 183893 clothianidin | 1:60 | 2.44 | 183.63 |
| CGA 183893 clothianidin | 1:80 | 2.63 | 171.28 |
As shown in Table 12, CGA 183893 and clothianidin to Fructus Lycopersici esculenti Bemisia tabaci proportioning when 1 80 ~ 60 1, co-toxicity coefficient is all higher than 120, illustrate that both all show potentiation at mixture in the range of 1 80 ~ 60 1, when the proportioning of CGA 183893 and clothianidin is 1 25 ~ 10 1, potentiation becomes apparent from highlighting, and co-toxicity coefficient is all higher than 210.Wherein when CGA 183893 and clothianidin weight ratio are 2:5, co-toxicity coefficient is maximum, and potentiation is the most obvious.Testing discovery CGA 183893 through applicant is 10:1 with clothianidin proportioning, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:15, 1:20, during 1:25, to the planthopper in various crop, rice leaf roller, striped rice borer, yellow rice borer, trialeurodes vaporariorum, Bemisia tabaci, aphid, thrips, Anoplophorae seu Aprionae, scale insect, tea lesser leafhopper, bollworm, cotton boll as, beet armyworm, rice green leafhopper, the preventing and treating of diamondback moth has obvious potentiation potentiation obvious, co-toxicity coefficient is all higher than 120.
Application Example five
For examination insect: Fructus Solani melongenae thrips
Test medicine is provided by Shanxi Thompson Biological Technology Co., Ltd..
EXPERIMENTAL DESIGN: determine CGA 183893 and the former medicine of MTI-446 and effective lethasl concentration scope of the two different ratio mixture through pilot study.
Table 13 CGA 183893 toxicity test analysis of results table to Fructus Solani melongenae thrips compounding with MTI-446
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| CGA 183893 | — | 2.01 | — |
| MTI-446 | — | 2.95 | — |
| CGA 183893 MTI-446 | 60:1 | 1.24 | 162.95 |
| CGA 183893 MTI-446 | 40:1 | 1.19 | 170.23 |
| CGA 183893 MTI-446 | 30:1 | 1.12 | 181.33 |
| CGA 183893 MTI-446 | 20:1 | 0.98 | 208.26 |
| CGA 183893 MTI-446 | 10:1 | 0.96 | 215.62 |
| CGA 183893 MTI-446 | 1:1 | 1.08 | 221.38 |
| CGA 183893 MTI-446 | 2:3 | 0.96 | 258.86 |
| CGA 183893 MTI-446 | 1:5 | 1.19 | 229.96 |
| CGA 183893 MTI-446 | 1:15 | 1.31 | 218.78 |
| CGA 183893 MTI-446 | 1:30 | 1.39 | 209.06 |
| CGA 183893 MTI-446 | 1:40 | 1.56 | 186.96 |
| CGA 183893 MTI-446 | 1:60 | 1.64 | 178.50 |
| CGA 183893 MTI-446 | 1:80 | 1.78 | 164.77 |
As shown in Table 13, CGA 183893 and MTI-446 to Fructus Solani melongenae thrips proportioning when 1 80 ~ 60 1, co-toxicity coefficient is all higher than 120, illustrate that both all show potentiation at mixture in the range of 1 80 ~ 60 1, when the proportioning of CGA 183893 and MTI-446 is 1 30 ~ 20 1, potentiation becomes apparent from highlighting, and co-toxicity coefficient is all higher than 205.Wherein when CGA 183893 and MTI-446 weight ratio are 2:3, co-toxicity coefficient is maximum, and potentiation is the most obvious.Testing discovery CGA 183893 through applicant is 20:1 with MTI-446 proportioning, 15:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:15, 1:20, 1:25, to the planthopper in various crop during 1:30, rice leaf roller, striped rice borer, yellow rice borer, trialeurodes vaporariorum, Bemisia tabaci, aphid, thrips, Anoplophorae seu Aprionae, scale insect, tea lesser leafhopper, bollworm, cotton boll as, beet armyworm, rice green leafhopper, the preventing and treating of diamondback moth has obvious potentiation potentiation obvious, co-toxicity coefficient is all higher than 120.
Application Example six CGA 183893 and active component B and compounding prevent and treat the rice hoppers test of pesticide effectiveness
This test arrangement is at Shaanxi Province's Hanzhong City, test medicine is researched and developed by Shanxi Thompson Biological Technology Co., Ltd., is provided, comparison medicament 20% CGA 183893 suspending agent (autogamy), 25% Diacloden wettable powder (commercial), 40% thiacloprid suspending agent (autogamy), 50% clothianidin wettable powder (autogamy), 20% MTI-446 wettable powder (autogamy).
Investigate rice hoppers insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 1 day, 3 days, 7 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 14 CGA 183893 and active component B and compounding prevent and treat the rice hoppers test of pesticide effectiveness
As can be seen from Table 14, can effectively prevent and treat rice hoppers after CGA 183893 is compounding with active component B, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example seven CGA 183893 and active component B and the compounding preventing and treating Fructus Cucumidis sativi trialeurodes vaporariorum test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, test medicine is researched and developed by Shanxi Thompson Biological Technology Co., Ltd., is provided, comparison medicament 20% CGA 183893 suspending agent (autogamy), 25% Diacloden wettable powder (commercial), 40% thiacloprid suspending agent (autogamy), 50% clothianidin wettable powder (autogamy), 20% MTI-446 wettable powder (autogamy).
Investigate Fructus Cucumidis sativi trialeurodes vaporariorum insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 1 day, 3 days, 7 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 15 CGA 183893 and active component B and the compounding preventing and treating Fructus Cucumidis sativi trialeurodes vaporariorum test of pesticide effectiveness thereof
As can be seen from Table 15, can effectively prevent and treat Fructus Cucumidis sativi trialeurodes vaporariorum after CGA 183893 is compounding with active component B, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example eight CGA 183893 and active component B and the compounding preventing and treating cotton aphid test of pesticide effectiveness thereof
This test arrangement is in Weinan City Dali County, Shaanxi Province, test medicine is researched and developed by Shanxi Thompson Biological Technology Co., Ltd., is provided, comparison medicament 20% CGA 183893 suspending agent (autogamy), 25% Diacloden wettable powder (commercial), 40% thiacloprid suspending agent (autogamy), 50% clothianidin wettable powder (autogamy), 20% MTI-446 wettable powder (autogamy).
Investigate cotton aphid insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 1 day, 3 days, 7 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 16 CGA 183893 and active component B and the compounding preventing and treating cotton aphid test of pesticide effectiveness thereof
As can be seen from Table 16, CGA 183893 and active component B and compounding preventing and treating cotton aphid thereof, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine CGA 183893 and active component B and the compounding preventing and treating apple aphid test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, test medicine is researched and developed by Shanxi Thompson Biological Technology Co., Ltd., is provided, comparison medicament 20% CGA 183893 suspending agent (autogamy), 25% Diacloden wettable powder (commercial), 40% thiacloprid suspending agent (autogamy), 50% clothianidin wettable powder (autogamy), 20% MTI-446 wettable powder (autogamy).
Investigate apple tree aphid insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 1 day, 3 days, 7 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 17 CGA 183893 and active component B and compounding preventing and treating apple tree Control of Aphids thereof
As can be seen from Table 17, energy effectively preventing and treating apple-tree aphid after CGA 183893 is compounding with active component B, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten CGA 183893 and active component B and compounding prevent and treat the Camellia sinensis tea lesser leafhopper test of pesticide effectiveness
This test arrangement is in Ya'an, Sichuan Province, test medicine is researched and developed by Shanxi Thompson Biological Technology Co., Ltd., is provided, comparison medicament 20% CGA 183893 suspending agent (autogamy), 25% Diacloden wettable powder (commercial), 40% thiacloprid suspending agent (autogamy), 50% clothianidin wettable powder (autogamy), 20% MTI-446 wettable powder (autogamy).
Investigate Camellia sinensis tea lesser leafhopper insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 1 day, 3 days, 7 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 18 CGA 183893 and active component B and compounding prevent and treat the Camellia sinensis tea lesser leafhopper test of pesticide effectiveness
As can be seen from Table 18, can effectively prevent and treat Camellia sinensis tea lesser leafhopper after CGA 183893 is compounding with active component B, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 CGA 183893 and active component B and the compounding preventing and treating flowers thrips test of pesticide effectiveness thereof
This test arrangement is in nursery, Xi'an City, Shanxi Province, test medicine is researched and developed by Shanxi Thompson Biological Technology Co., Ltd., is provided, comparison medicament 20% CGA 183893 suspending agent (autogamy), 25% Diacloden wettable powder (commercial), 40% thiacloprid suspending agent (autogamy), 50% clothianidin wettable powder (autogamy), 20% MTI-446 wettable powder (autogamy).
Investigate flowers thrips insect pest index before medicine, in insect pest early period of origination dispenser, within after dispenser 1 day, 3 days, 7 days, investigate insect pest indexes and calculate preventive effect.Result of the test is as follows:
Table 19 CGA 183893 and active component B and the compounding preventing and treating flowers thrips test of pesticide effectiveness thereof
As can be seen from Table 19, CGA 183893 and active component B and compounding preventing and treating flowers thrips thereof, prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, to the planthopper in various crop, rice leaf roller, striped rice borer, yellow rice borer, trialeurodes vaporariorum, Bemisia tabaci, aphid, thrips, Anoplophorae seu Aprionae, scale insect, tea lesser leafhopper, bollworm, cotton boll as the preventive effect of the common insect pests such as, beet armyworm, rice green leafhopper, diamondback moth is all more than 95% after CGA 183893 and Diacloden, thiacloprid, clothianidin, MTI-446 are compounding, being better than single dose preventive effect, potentiation is obvious.
Claims (4)
1. the Pesticidal combination containing CGA 183893 with anabasine, effective active composition is active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1 20 ~ 10 1, and described active components A is CGA 183893, and active component B is Diacloden.
Pesticidal combination containing CGA 183893 Yu anabasine the most according to claim 1, it is characterised in that: compositions makes wettable powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
Pesticidal combination containing CGA 183893 with anabasine the most according to claim 1 is used for preventing and treating the purposes of insect on crops.
Purposes the most according to claim 3, it is characterized in that, described insect is: planthopper, rice leaf roller, striped rice borer, yellow rice borer, trialeurodes vaporariorum, Bemisia tabaci, aphid, thrips, Anoplophorae seu Aprionae, scale insect, tea lesser leafhopper, bollworm, cotton boll are as, beet armyworm, rice green leafhopper, diamondback moth.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210151878.6A CN103416419B (en) | 2012-05-16 | 2012-05-16 | A kind of Pesticidal combination containing CGA 183893 Yu anabasine |
| CN201610221118.6A CN105766983B (en) | 2012-05-16 | 2012-05-16 | A kind of Pesticidal combination containing CGA 183893 and anabasine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210151878.6A CN103416419B (en) | 2012-05-16 | 2012-05-16 | A kind of Pesticidal combination containing CGA 183893 Yu anabasine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610221118.6A Division CN105766983B (en) | 2012-05-16 | 2012-05-16 | A kind of Pesticidal combination containing CGA 183893 and anabasine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103416419A CN103416419A (en) | 2013-12-04 |
| CN103416419B true CN103416419B (en) | 2016-08-03 |
Family
ID=49642226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210151878.6A Active CN103416419B (en) | 2012-05-16 | 2012-05-16 | A kind of Pesticidal combination containing CGA 183893 Yu anabasine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103416419B (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009118312A1 (en) * | 2008-03-28 | 2009-10-01 | Novartis Ag | Dicyclanil formulation |
-
2012
- 2012-05-16 CN CN201210151878.6A patent/CN103416419B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009118312A1 (en) * | 2008-03-28 | 2009-10-01 | Novartis Ag | Dicyclanil formulation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103416419A (en) | 2013-12-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103563901B (en) | A kind of Efficient insecticidal composition containing propylene glycol alginate | |
| CN104430473A (en) | Compounded insecticidal composition containing trifluorobenzene pyrimidine | |
| CN103563950B (en) | Pesticide composition | |
| CN104430365A (en) | Efficient insecticidal composition containing trifluorobenzene pyrimidine | |
| CN103563962B (en) | A kind of Pesticidal combination containing propylene glycol alginate and anabasine | |
| CN103931630A (en) | Insecticide composition containing SYP9080 | |
| CN103651403B (en) | A kind of Efficient insecticidal composition containing Spiromesifen | |
| CN105613559A (en) | Insecticidal composition containing spiromesifen and neonicotinoids | |
| CN105104383A (en) | Efficient insecticide composition containing spiromesifen | |
| CN103651498A (en) | Insecticidal composition containing spiromesifen | |
| CN105794825A (en) | Insecticide composition containing tetrachlorantraniliprole and carbamic acid esters | |
| CN103651548B (en) | A kind of Pesticidal combination containing Spiromesifen | |
| CN103416419B (en) | A kind of Pesticidal combination containing CGA 183893 Yu anabasine | |
| CN105746582A (en) | Pesticide composition containing harpin protein and anabasine | |
| CN103503876B (en) | A kind of brominated worm Benzoylamide and the Pesticidal combination of neires toxin | |
| CN105794859A (en) | Insecticidal compound containing conidioblous thromboides and biological sources | |
| CN103621548B (en) | A kind of Pesticidal combination containing Spiromesifen and pyrethroid | |
| CN105766983A (en) | Insecticide composition prepared from dicycla strongil and anabasine | |
| CN105746540A (en) | Insecticidal composition containing tetrachloro insect amide | |
| CN105638719A (en) | Pesticide insecticidal composition containing Wufuchongzong | |
| CN103416413B (en) | A kind of composition pesticide containing CGA 183893 | |
| CN104738064B (en) | A kind of composition pesticide containing Spiromesifen and carbamatess | |
| CN104430484A (en) | Insecticidal composition containing trifluoro-phenylpyridine and pyrethroids | |
| CN105746526A (en) | Insecticidal composition containing tetrachloro insect amide and biological sources | |
| CN103960294A (en) | Insecticidal composition containing conidioblous thromboides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| OL01 | Intention to license declared | ||
| OL01 | Intention to license declared |