CN103408946B - Konjac glucomannan composite gel-containing baby nipple and preparation method thereof - Google Patents
Konjac glucomannan composite gel-containing baby nipple and preparation method thereof Download PDFInfo
- Publication number
- CN103408946B CN103408946B CN201310297629.2A CN201310297629A CN103408946B CN 103408946 B CN103408946 B CN 103408946B CN 201310297629 A CN201310297629 A CN 201310297629A CN 103408946 B CN103408946 B CN 103408946B
- Authority
- CN
- China
- Prior art keywords
- nipple
- composite gel
- parts
- baby nipple
- konjak
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
The invention relates to a konjac glucomannan composite gel-containing baby nipple and a preparation method of the konjac glucomannan composite gel-containing baby nipple. The preparation method comprises the following steps: preparing chitosan acetic acid solution, konjac glucomannan composite gel solution, base polymer vinyl silicone oil, konjac glucomannan composite gel-containing baby nipple rubber material, component A, component B and the konjac glucomannan composite gel-containing baby nipple. The base rubber material of the nipple is prepared by mixing the konjac glucomannan composite gel solution and the base polymer vinyl silicone oil, and is made by utilizing the high antibacterial property and gel property of the konjac glucomannan; carrageenan and xanthan gum are also added, so that the gel strength, the breaking resistance and the elongation of the konjac glucomannan composite gel-containing baby nipple can be improved, and the soft gel with better elasticity and cohesion can be formed; the konjac glucomannan composite gel-containing baby nipple has the advantages of being non-toxic, tasteless, transparent in color, antibacterial, soft, good in elasticity, tear-resistant and tensile, having true feeling of a real nipple and the like, and the safety and the using performance of the baby nipple are completely in accordance with the related standards in China.
Description
Technical field
The present invention relates to a kind of baby nipple and preparation method thereof, be specifically related to a kind of baby nipple containing konjak glycan composite gel and preparation method thereof.
Background technology
Nipple directly with the oral contact of baby, its material safe particularly important, and baby due to the age little, resistibility is poor, is very easy to come to harm.Therefore, that selects the nipple of safety to become very is important.
Australia is in disclosing the ban about forbidding using dihydroxyphenyl propane (BPA) in baby nipple and permanent tooth gutta-percha product at " federal law publication ", this ban comes into force on January 1st, 2012.
According to expert introduction, the chemicals quality separated out when residue on evaporation is and reflects that feeding bottle and nipple in use meet water, vinegar, wine, wet goods liquid.
The material making baby nipple has rubber also to have silica gel.Rubber nipple is also latex nipple, take natural rubber as goods, with nipple closely, yellow, flexible softness, but easily aging, have rubber taste, after having used for some time (general 4-6 week), nipple color relation can dimmed brown, and is with viscosity, and sulphur content very easily exceeds standard.Silica gel nipple, colourless, tasteless, nontoxic, high temperature resistant, low temperature resistant, not containing dihydroxyphenyl propane, any sterilization method is adopted also not easily to make it be out of shape, long sterilization does not have objectionable constituent yet and oozes out, and can not produce the peculiar smell such as plastics, but silica gel nipple compares with rubber nipple, hardness is much larger, does not have breast milk texture.
In recent years, there is a kind of novel silicon rubber nipple to put on market, instead of traditional latex, silica gel nipple gradually.Compared with latex nipple, this silicon rubber nipple has following advantage: (1) water boiling resistance, is not clamminess, not deliquescing after boiling, and is convenient to sterilization, free from extraneous odour when (2) suck or chew in mouth.But silicon rubber nipple heavy metal content and evaporation residue are very high, boiling for a long time has leachable, and containing the residual matter of volatility and normal hexane inside nipple, can cause chronic poisoning, and cause a lot of disease, cause very large harm to infantile health.
Occur again subsequently comprising the silicon rubber nipple adopting high-temperature hot sulphurated siliastic rubber unvulcanizate and add-on type liquid silicon rubber.Silicon rubber nipple has resistant to elevated temperatures characteristic, can through repeatedly boiling, not easily aging, time limit of service is extended, but the nipple adopting high-temperature hot sulphurated siliastic rubber unvulcanizate to make also has some problems: the formula adjustment difficulty of rubber unvulcanizate, easily occurs xanthochromia, have influence on outward appearance and the transparency of nipple, nipple goods need post cure, to eliminate the peculiar smell that remaining vulcanizing agent pyrolytic decomposition produces.
" Zhejiang chemical industry " the 42nd volume the 8th phase in 2011, article is numbered: the nipple adopting add-on type liquid silicon rubber injection molding to make in " development of the virgin nipple liquid silastic of baby " of the 1006-4184(2011) people such as 08-0021-03 Chen Li cloud research overcomes above-mentioned shortcoming preferably, but due to the restriction of composition of raw materials and proportioning raw materials, the hardness of these nipple goods is mostly shore 40 ~ 50 degree, larger with the texture difference of breast of mothers.
Application number is patent of invention " liquid silicon rubber composition for breast nursing simulated baby nipple and prepare the method for nipple " (applying date: 2009.08.19) principal character of 200910042100.x is a kind of method disclosing liquid silicon rubber composition for breast nursing simulated baby nipple and prepare nipple, in the present invention, breast nursing simulated baby nipple has resistant to elevated temperatures characteristic, can through repeatedly boiling, not easily aging, time limit of service is extended, but composition of raw materials and the proportioning raw materials of these nipple goods still inherently do not change, hardness is relatively large, still larger with real feel of breast milk baby nipple difference, and silica gel has very strong adsorptive power, desiccation this point can be produced to the skin of people not improve.
Application number be 201110380860.9 patent of invention " a kind of silicon rubber compound special for pacifier and preparation method thereof " (applying date: 2011.11.25) principal character be disclose a kind of silicon rubber compound special for pacifier and preparation method thereof, in the present invention, nipple has the characteristic of high-clarity, shrinking percentage is little, elasticity is good, also higher anti tear degree is had, elongation, but the composition of raw materials of these nipple goods and proportioning raw materials still can cause nipple hardness relatively large, still larger with real feel of breast milk baby nipple difference, and do not solve silica gel and have very strong adsorptive power and the problem such as not antibacterial.
Therefore, a kind of nonpoisonous and tasteless, color transparent, antibacterial, very soft and have elastic, baby can maintain when sucking certain wettability, anti tear, urgently our research and development of the real feel of breast milk nipple of stretch-proof.
Summary of the invention
The object of this invention is to provide a kind of baby nipple containing konjak glycan composite gel and preparation method thereof.The mixing of konjak glycan composite gel solution and base polymer vinyl silicone oil is utilized to make the sizing of baby nipple, utilize high germ resistance, high-moisture-retention, the gelation of Rhizoma amorphophalli glucomannan, and add carrageenin and xanthan gum and improve containing the gel-strength of konjak glycan composite gel baby nipple, bursting strength and elongation, add chitosan and improve antibacterial strength containing konjak glycan composite gel baby nipple.
The object of the invention is to realize by the following method.
Containing a preparation method for the baby nipple of konjak glycan composite gel, it is characterized in that step is as follows:
(1) prepare chitosan acetic acid solution: count by weight, get 2 ~ 5 parts of chitosans, join in the acetic acid aqueous solution of pH3 ~ 3.5 of 100 parts, stir and be no less than 10min, obtain chitosan acetic acid solution;
(2) konjak glycan composite gel solution is prepared: count by weight, the potassium sorbate of 1 ~ 2 part of phenylformic acid and 2 ~ 5 parts is added in 100 parts of water, 15 ~ 20 parts of Rhizoma amorphophalli glucomannans, 5 ~ 10 parts of carrageenins are added after stirring and dissolving, 6 ~ 10 parts of xanthan gum, 1 ~ 2 part of Repone K, 0.5 ~ 1 part of sodium alginate, stir 0.5 ~ 1h, then the chitosan acetic acid solution 5 ~ 10 parts of step (1) is added, in magnetic stirring apparatus, with 500r/min stirring and dissolving, obtain konjak glycan composite gel solution;
(3) base polymer vinyl silicone oil is prepared: will be connected in there-necked flask with the nitrogen pot of filtration unit and vacuum air pump, temperature is regulated to be vacuumize after 50 ~ 60 DEG C, then under the condition keeping logical nitrogen, add 100 parts of octamethylcyclotetrasiloxanes and 1 part of initiator five water Tetramethylammonium hydroxide to there-necked flask, stir 1.5 ~ 2.5h with electric blender 800r/min; Then add 50 parts of methyl ethylene cyclotetrasiloxanes, at 70 ~ 75 DEG C, constant temperature is with raised temperature to 150 ~ 160 DEG C after 800r/min stirring 1 ~ 1.5h, and constant temperature stirs 1 ~ 1.5h with 800r/min; Raised temperature to 180 ~ 200 DEG C again, naturally cooling after continuation stirring 3 ~ 3.5h, then removes vacuum and closes nitrogen; Namely product after naturally cooling is base polymer vinyl silicone oil;
(4) preparation is containing the baby nipple sizing material of konjak glycan composite gel: the base polymer vinyl silicone oil getting the konjak glycan composite gel solution of step (2), step (3), and thermal silica, mix according to the weight ratio of 3:2:0.5, pH to 8 ~ 12 are regulated with the edible aqua calcis that weight concentration is 2% ~ 5%, 100 DEG C ~ 120 DEG C are first warming up in vacuum kneader, airtight kneading final vacuum insulation kneading 1 ~ 1.5h, be cooled to 20 ~ 30 DEG C again, obtain paste, for subsequent use;
(5) prepare component A and B component: the paste getting step (4), the proportioning adding 5mg platinum catalyst by 1kg paste mixes, and row's bubble, filtration obtain component A; The proportioning separately adding 10mg ethyl containing hydrogen silicone oil linking agent by 1kg paste mixes, and row's bubble, filters and obtains B component;
(6) preparation is containing the baby nipple of konjak glycan composite gel: by A, B two component obtained in step (5), injected the baby nipple mould of multimode cavity after mixing by 1:1 volume ratio by liquid-state silicon gel baby nipple injection moulding machine, after sulfidization molding, be the baby nipple containing konjak glycan composite gel.
Described Rhizoma amorphophalli glucomannan, acetic acid, chitosan, carrageenin, xanthan gum, Repone K, phenylformic acid, potassium sorbate, sodium alginate, calcium hydroxide are food grade; Thermal silica, ethyl containing hydrogen silicone oil linking agent are technical grade, are buied by market.
The present invention goes back the baby nipple containing konjak glycan composite gel prepared by Sustainable use aforesaid method.
Advantage of the present invention: the baby nipple containing konjak glycan composite gel of the present invention is the sizing utilizing the mixing of konjak glycan composite gel solution and base polymer vinyl silicone oil to make nipple, utilizes the high germ resistance of Rhizoma amorphophalli glucomannan, gelation makes; And add carrageenin and xanthan gum, improve the gel-strength of the baby nipple containing konjak glycan composite gel, bursting strength and elongation, add the antibacterial strength that chitosan improves the baby nipple containing konjak glycan composite gel.Rhizoma amorphophalli glucomannan, carrageenin and xanthan gum all belong to water miscible natural polysaccharide, Rhizoma amorphophalli glucomannan and carrageenin all can form gel, and xanthan gum self does not form the characteristic of gel, but there is good compatibleness in thickening, high temperature resistant and gel synergizing.Konjak portuguese gansu polyose gel and carrageenin have extraordinary synergy, significantly can strengthen gel-strength and the elasticity of konjak portuguese gansu polyose gel, can also reduce the bleed of konjak portuguese gansu polyose gel.Konjak portuguese gansu polyose gel and xanthan gum interworking significantly can increase the stickiness of colloid, can also reduce the usage quantity of konjak portuguese gansu polyose gel, can form solid gel.Carrageenin is same with xanthan gum has fine compatibility, can form the gel of softness, more flexible and force of cohesion; In addition, xanthan gum can also reduce the dehydration contracting adduction of carrageenin.
Security and the use properties of a kind of baby nipple containing konjak glycan composite gel of the present invention meet relative national standards requirement completely, nonpoisonous and tasteless, color is transparent, antibacterial, soft and have elasticity, anti tear, stretch-proof, there is real feel of breast milk.The present invention with the addition of Rhizoma amorphophalli glucomannan and chitosan, and chitosan is that occurring in nature is only second to cellulosic second largest biological polyoses, has good biocompatibility, biodegradability and the good characteristic such as antibacterial, anticorrosion; Rhizoma amorphophalli glucomannan is a kind of natural plant polyose, and have excellent retentiveness, germ resistance and tensile strength are large, snappiness is good, and tensile strength, bursting strength are high.Liquid-state silicon gel contained by the present invention, be food grade material, nonpoisonous and tasteless, color is transparent, not containing dihydroxyphenyl propane, water-fast moistureproofness is good, good stability, do not make moist in room temperature 25 DEG C sealing, do not meet high temperature and can place and never degenerate for more than at least 1 year, chemical proofing is good, acid-and base-resisting and number of chemical medicine.Detect baby nipple of the present invention and latex nipple, the normal hexane of usual silicone rubber nipple, the residual matter of volatility, result is as shown in table 1.
The security of table 1 baby nipple of the present invention and conventional nipple contrasts
A kind of baby nipple containing konjak glycan composite gel of the present invention and latex nipple, usual silicone rubber nipple are done following performance test:
(1) suck rear lips moist degree: get a kind of baby nipple containing konjak glycan composite gel of the present invention respectively and latex nipple, usual silicone rubber nipple allow 3 babies suck half an hour, after half hour, observe the dry and cracked degree of lip of baby.
(2) germ resistance: test after a kind of baby nipple containing konjak glycan composite gel and latex nipple, usual silicone rubber nipple allow 3 babies suck half an hour, do not carry out disinfection, the indigenous flora on 3 nipples is detected (Standard Selection in conjunction with QB/T 2591-2003 supplies bacterium).
(3) breast milk texture: get a kind of baby nipple containing konjak glycan composite gel of the present invention and latex nipple, usual silicone rubber nipple respectively, be affectedly bashful the elasticity and flexibility of observing them.
Above testing of characteristic result is as shown in table 2.
Table 2 is containing the baby nipple of konjak glycan composite gel and the performance comparison of conventional nipple
Through above contrast test, a kind of baby nipple level of security containing konjak glycan composite gel of the present invention is high, and germ resistance is good, baby sucks rear lip can not be dry, and maintain certain wettability, and breast milk texture is strong, be the nipple that baby enjoys a lot, there is fabulous development prospect.
specific embodiment
Below in conjunction with embodiment, the present invention is further elaborated.
Embodiment 1: a kind of preparation method containing konjak glycan composite gel baby nipple
Containing a preparation method for konjak glycan composite gel baby nipple, comprise the following steps:
(1) prepare chitosan acetic acid solution: count by weight, get 5 parts of chitosans, join in the acetic acid aqueous solution of the pH3 of 100 parts, stir 10min, obtain chitosan acetic acid solution;
(2) preparation of konjak glycan composite gel solution: count by weight, the potassium sorbate of 2 parts of phenylformic acid and 5 parts is added in 100 parts of water, 20 parts of Rhizoma amorphophalli glucomannans, 5 parts of carrageenins are added after stirring and dissolving, 10 parts of xanthan gum, 2 parts of Repone K, 1 part of sodium alginate stir 1h, then the chitosan acetic acid solution 8 parts of step (1) is added, in magnetic stirring apparatus, with 500r/min stirring and dissolving, obtain konjak glycan composite gel solution;
(3) preparation of base polymer vinyl silicone oil: will be connected in there-necked flask with the nitrogen pot of filtration unit and vacuum air pump, temperature is regulated to be vacuumize after 50 DEG C, then under the condition keeping logical nitrogen, add 100 parts of octamethylcyclotetrasiloxanes and 1 part of initiator five water Tetramethylammonium hydroxide to there-necked flask, stir 1.5h with electric blender 800r/min; Then add 50 parts of methyl ethylene cyclotetrasiloxanes, at 75 DEG C, constant temperature is with raised temperature to 160 DEG C after 800r/min stirring 1.5h, and constant temperature stirs 1.5h with 800r/min; Raised temperature to 200 DEG C again, naturally cooling after continuation stirring 3h, then removes vacuum and closes nitrogen; Namely product after naturally cooling is base polymer vinyl silicone oil;
(4) containing the preparation of the baby nipple sizing material of konjak glycan composite gel: the base polymer vinyl silicone oil getting the konjak glycan composite gel solution of step (2), step (3), and thermal silica, mix according to the weight ratio of 3:2:0.5, pH to 9 is regulated with the edible aqua calcis that weight concentration is 5%, in vacuum kneader, be first warming up to 120 DEG C, 1h is mediated in airtight kneading final vacuum insulation, then is cooled to 25 DEG C, obtain paste, for subsequent use; Described vacuum kneader is NH-300 vacuum kneader, mixes oar rotating speed 21 ~ 37rpm, steam heating pressure 0.3 ~ 0.5MPa, vacuum tightness 0.094 MPa, capacity 1600kg;
(5) prepare component A and B component: the paste getting step (4), the proportioning adding 5mg platinum catalyst by 1kg paste mixes, and row's bubble, filtration obtain component A; The proportioning separately adding 10mg ethyl containing hydrogen silicone oil linking agent by 1kg paste mixes, and row's bubble, filters and obtains B component; Described ethyl containing hydrogen silicone oil linking agent is buied by market, and viscosity is 1 ~ 5 × 10-2pas.Relative density 0.98 ~ 1.10; Specific refractory power 1.390 ~ 1.420, hydrogen richness 0.8% ~ 1.2%.Under platinum catalyst effect, Si-H key can carry out addition reaction with alkene;
(6) liquid silicon composite gum injection molding technique prepares baby nipple: by A, B two component obtained in step (5), injected the baby nipple mould of multimode cavity after mixing by 1:1 volume ratio by liquid-state silicon gel baby nipple injection moulding machine, after sulfidization molding, be the baby nipple containing konjak glycan composite gel; The model of described liquid-state silicon gel baby nipple injection moulding machine is SLK-LSR-80, the operational condition of technique: injection moulding machine internal pressure 2-8MPa, curing temperature 150-250 DEG C, curing time 15s-25s, material viscosity 50-200Pa.s, shaping cycle (till playing injection next time from injection) 10s-15s.
The foregoing is only preferred embodiment of the present invention, all equalizations done according to the present patent application the scope of the claims change and modify, and all should belong to covering scope of the present invention.
Claims (2)
1., containing a preparation method for the baby nipple of konjak glycan composite gel, it is characterized in that step is as follows:
(1) prepare chitosan acetic acid solution: count by weight, get 2 ~ 5 parts of chitosans, join in the acetic acid aqueous solution of pH3 ~ 3.5 of 100 parts, stir and be no less than 10min, obtain chitosan acetic acid solution;
(2) configuration of konjak glycan composite gel solution: count by weight, the potassium sorbate of 1 ~ 2 part of phenylformic acid and 2 ~ 5 parts is added in 100 parts of water, 15 ~ 20 parts of Rhizoma amorphophalli glucomannans, 5 ~ 10 parts of carrageenins are added after stirring and dissolving, 6 ~ 10 parts of xanthan gum, 1 ~ 2 part of Repone K, 0.5 ~ 1 part of sodium alginate, stir 0.5 ~ 1h, then the chitosan acetic acid solution 5 ~ 10 parts of step (1) is added, in magnetic stirring apparatus, with 500r/min stirring and dissolving, obtain konjak glycan composite gel solution;
(3) preparation of base polymer vinyl silicone oil: will be connected in there-necked flask with the nitrogen pot of filtration unit and vacuum air pump, temperature is regulated to be vacuumize after 50 ~ 60 DEG C, then under the condition keeping logical nitrogen, add 100 parts of octamethylcyclotetrasiloxanes and 1 part of initiator five water Tetramethylammonium hydroxide to there-necked flask, stir 1.5 ~ 2.5h with electric blender 800r/min; Then add 50 parts of methyl ethylene cyclotetrasiloxanes, at 70 ~ 75 DEG C, constant temperature is with raised temperature to 150 ~ 160 DEG C after 800r/min stirring 1 ~ 1.5h, and constant temperature stirs 1 ~ 1.5h with 800r/min; Raised temperature to 180 ~ 200 DEG C again, naturally cooling after continuation stirring 3 ~ 3.5h, then removes vacuum and closes nitrogen; Base polymer vinyl silicone oil is obtained after naturally cooling;
(4) containing the preparation of the baby nipple sizing material of konjak glycan composite gel: the base polymer vinyl silicone oil getting the konjak glycan composite gel solution of step (2), step (3), and thermal silica, mix according to the weight ratio of 3:2:0.5, pH to 8 ~ 12 are regulated with the edible aqua calcis that weight concentration is 2% ~ 5%, 100 DEG C ~ 120 DEG C are first warming up in vacuum kneader, airtight kneading final vacuum insulation kneading 1 ~ 1.5h, be cooled to 20 ~ 30 DEG C again, obtain paste, for subsequent use;
(5) prepare component A and B component: the paste getting step (4), the proportioning adding 5mg platinum catalyst by 1kg paste mixes, and row's bubble, filtration obtain component A; The proportioning separately adding 10mg ethyl containing hydrogen silicone oil linking agent by 1kg paste mixes, and row's bubble, filters and obtains B component;
(6) liquid silicon composite gum injection molding technique prepares baby nipple: by A, B two component obtained in step (5), injected the baby nipple mould of multimode cavity after mixing by 1:1 volume ratio by liquid-state silicon gel baby nipple injection moulding machine, after sulfidization molding, be the baby nipple containing konjak glycan composite gel.
2. the baby nipple containing konjak glycan composite gel prepared by the method for claim 1.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310297629.2A CN103408946B (en) | 2013-07-16 | 2013-07-16 | Konjac glucomannan composite gel-containing baby nipple and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310297629.2A CN103408946B (en) | 2013-07-16 | 2013-07-16 | Konjac glucomannan composite gel-containing baby nipple and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103408946A CN103408946A (en) | 2013-11-27 |
CN103408946B true CN103408946B (en) | 2015-04-29 |
Family
ID=49601991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310297629.2A Expired - Fee Related CN103408946B (en) | 2013-07-16 | 2013-07-16 | Konjac glucomannan composite gel-containing baby nipple and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN103408946B (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104109389A (en) * | 2014-06-19 | 2014-10-22 | 滁州天成有机硅高分子材料有限公司 | Silicone rubber compound for producing rubber nipples |
CN104341779A (en) * | 2014-10-28 | 2015-02-11 | 宁波爱乐宝婴儿用品有限公司 | Antibacterial nipple and preparation method thereof |
CN104292571A (en) * | 2014-10-28 | 2015-01-21 | 宁波爱乐宝婴儿用品有限公司 | Infant pacifier containing konjac glucomannan composite gel and preparation method thereof |
CN105419344A (en) * | 2015-12-22 | 2016-03-23 | 王璐 | Novel antibacterial nipple and preparation method thereof |
CN105482464A (en) * | 2015-12-22 | 2016-04-13 | 王璐 | Nipple containing plant extract and preparation method thereof |
CN105504828A (en) * | 2015-12-22 | 2016-04-20 | 王璐 | Nipple containing plant extract and preparation method of nipple |
CN105482463A (en) * | 2015-12-22 | 2016-04-13 | 王璐 | Novel anti-microbial nipple and preparation method thereof |
CN106009066B (en) * | 2016-06-17 | 2019-02-05 | 昆明理工大学 | A method of nano material is prepared using konjaku glucomannan and chitosan |
CN106722127A (en) * | 2016-11-15 | 2017-05-31 | 福建农林大学 | A kind of konjaku glucomannan baby teeth grinding rod and preparation method thereof |
CN107099061B (en) * | 2017-05-22 | 2019-03-12 | 福建农林大学 | A kind of konjaku glucomannan disposable syringe and preparation method thereof |
CN110964324A (en) * | 2019-12-20 | 2020-04-07 | 佛山科学技术学院 | Antibacterial aromatic gutta-percha for infants |
CN111978600B (en) * | 2020-09-02 | 2022-07-01 | 山东华熙海御生物医药有限公司 | Hyaluronic acid composite gel for pacifying nipple |
MX2023003016A (en) | 2020-09-22 | 2023-04-10 | Swimc Llc | Chitosan-containing coating compositions. |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1182231A1 (en) * | 2000-08-11 | 2002-02-27 | General Electric Company | High tear strength low compression set heat curable silicone elastomer |
EP1361253A1 (en) * | 2002-05-01 | 2003-11-12 | Shin-Etsu Chemical Co., Ltd. | Addition curable silicone rubber compositions |
CN101104700A (en) * | 2007-08-18 | 2008-01-16 | 青岛科技大学 | Radiation vulcanizing method for environment-friendly type medical rubber products |
CN101463189A (en) * | 2007-12-18 | 2009-06-24 | 吴海涛 | Medical polymer biological antibacterial gloves |
CN101565546A (en) * | 2008-04-21 | 2009-10-28 | 曲奕 | Bios antibacterial glue film |
CN101649115A (en) * | 2009-08-19 | 2010-02-17 | 中山市聚合电子材料有限公司 | Liquid silicon rubber composition for breast nursing simulated baby nipple and method for making nipple |
JP2013064090A (en) * | 2011-09-20 | 2013-04-11 | Shin-Etsu Chemical Co Ltd | Addition-curable silicone rubber composition and cured product thereof |
JP2013064089A (en) * | 2011-09-20 | 2013-04-11 | Shin-Etsu Chemical Co Ltd | Addition-curable silicone rubber composition and cured product thereof |
-
2013
- 2013-07-16 CN CN201310297629.2A patent/CN103408946B/en not_active Expired - Fee Related
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1182231A1 (en) * | 2000-08-11 | 2002-02-27 | General Electric Company | High tear strength low compression set heat curable silicone elastomer |
EP1361253A1 (en) * | 2002-05-01 | 2003-11-12 | Shin-Etsu Chemical Co., Ltd. | Addition curable silicone rubber compositions |
CN101104700A (en) * | 2007-08-18 | 2008-01-16 | 青岛科技大学 | Radiation vulcanizing method for environment-friendly type medical rubber products |
CN101463189A (en) * | 2007-12-18 | 2009-06-24 | 吴海涛 | Medical polymer biological antibacterial gloves |
CN101565546A (en) * | 2008-04-21 | 2009-10-28 | 曲奕 | Bios antibacterial glue film |
CN101649115A (en) * | 2009-08-19 | 2010-02-17 | 中山市聚合电子材料有限公司 | Liquid silicon rubber composition for breast nursing simulated baby nipple and method for making nipple |
JP2013064090A (en) * | 2011-09-20 | 2013-04-11 | Shin-Etsu Chemical Co Ltd | Addition-curable silicone rubber composition and cured product thereof |
JP2013064089A (en) * | 2011-09-20 | 2013-04-11 | Shin-Etsu Chemical Co Ltd | Addition-curable silicone rubber composition and cured product thereof |
Also Published As
Publication number | Publication date |
---|---|
CN103408946A (en) | 2013-11-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103408946B (en) | Konjac glucomannan composite gel-containing baby nipple and preparation method thereof | |
CN103965564B (en) | Plasticized polyvinyl chloride material and preparation method thereof | |
CN102525995B (en) | Plant officinal hollow capsule and preparation method thereof | |
CN101538377A (en) | Cross-linked hyaluronic acid gel and preparation method thereof | |
CN104341779A (en) | Antibacterial nipple and preparation method thereof | |
CN107602952A (en) | A kind of hypo-allergenic, antibacterial and mouldproof Heveatex sponge material, its preparation method and application | |
CN106221241A (en) | A kind of medical dual composition addition type liquid silastic and preparation method thereof | |
CN104322674B (en) | A kind of yoghourt stabilizer and prepare the method for low-temperature yoghurt using it | |
CN109535728A (en) | A kind of high-performance food-grade addition type room temperature vulcanized silicone rubber and preparation method thereof | |
CN101781465B (en) | Method for preparing room-temperature fast-curing addition organic silicon rubber | |
CN104784148B (en) | A kind of film-forming composition for preparing plant capsule and preparation method thereof | |
CN106333575A (en) | Sleep pillow containing modified MDI (diphenylmethane diisocyanate) foam | |
CN101798433A (en) | Non-PVC material for medical infusion products and preparation method thereof | |
CN103788421A (en) | Disposable movement tooth protecting socket and preparation method thereof | |
CN106729729A (en) | A kind of Capsules plant amylum composition | |
CN106307518B (en) | A kind of water supply liquid food and preparation method thereof | |
CN103694489A (en) | Method for modifying natural emulsion through pulullan-alcohol soluble protein | |
JP2016020348A (en) | Compositions for dysphagia patients and methods for producing food for dysphagia patients | |
KR20110080239A (en) | Method for manufacturing fish noodle | |
CN103709582A (en) | Gutta percha material and preparation method thereof | |
JP6827725B2 (en) | Mochi-like texture dessert | |
CN105860164A (en) | Composite latex condom containing graphene oxide/fish glue and preparation method thereof | |
CN105295384A (en) | Medical silicone rubber and preparation method thereof | |
CN105482463A (en) | Novel anti-microbial nipple and preparation method thereof | |
CN105348817A (en) | Method for preparing anti-bacterial nipple from plant extract |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150429 Termination date: 20200716 |
|
CF01 | Termination of patent right due to non-payment of annual fee |