CN103386165A - IRE steep peak flat top cancer therapeutic instrument - Google Patents

IRE steep peak flat top cancer therapeutic instrument Download PDF

Info

Publication number
CN103386165A
CN103386165A CN2012101412029A CN201210141202A CN103386165A CN 103386165 A CN103386165 A CN 103386165A CN 2012101412029 A CN2012101412029 A CN 2012101412029A CN 201210141202 A CN201210141202 A CN 201210141202A CN 103386165 A CN103386165 A CN 103386165A
Authority
CN
China
Prior art keywords
switch
pulse generator
gate
electrode
ire
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2012101412029A
Other languages
Chinese (zh)
Inventor
张涛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN2012101412029A priority Critical patent/CN103386165A/en
Publication of CN103386165A publication Critical patent/CN103386165A/en
Pending legal-status Critical Current

Links

Images

Landscapes

  • Electrotherapy Devices (AREA)

Abstract

An IRE steep peak flat top cancer therapeutic instrument comprises a power supply, a rectifier, a pulse generator, an electrode with an endoscope, an oscilloscope, a medical CT, B ultrasound, the endoscope, a computer and relative accessories. Steep peak flat top pulses can be produced, lesion benign or malignant tumor cell tissues are precisely killed under guiding of the imaging technologies of the endoscope, the medical CT and the B ultrasound, the IRE steep peak flat top cancer therapeutic instrument is used for treating various tumors and cancers, the pulse generator is simply formed, and needed steep peak flat top pulse voltage can be obtained.

Description

IRE cliffy summit flat-top cancer treating instrument
Technical field
The present invention relates to a kind of medical therapy instrument, being used for the treatment of benign tumor and malignant tumor is the medical therapy instrument of cancer, also can be used for the auxiliary treatment of the treatment of other diseases.
Background technology
Malignant tumor has become the very high disease of mortality rate.Existing technology of cancer treatment method is mainly chemotherapy, gene therapy, Chinese traditional treatment and therapy of combining Chinese and Western medicine, gene therapy, ultrasonic therapy and Drug therapy, and take chemotherapy as main technique methods.These treatment technologies all can not or be difficult to the fundamentally diffusion of kill cancer cell and anticancer, and the side effect of chemotherapy is larger for patient's somatic damage, and medical expense is high.According to utilizing irreversible electric capacity hole steep-sided pulse technology treatment tumor, experiment shows that the treatment tumor effect is good, this but to plant the electronic and electrical equipment of key problem in technology device pulse generator complicated, complex manufacturing technology, the porch of the pulse that produces is precipitous not, top is uneven, so and, the present technical method that also there is no simply effectively to treat cancer.
Summary of the invention
The present invention is directed to above-mentioned technological deficiency, utilize the electricity physical characteristic of inductance and diode, invented the oncotherapy technical equipment IRE cliffy summit flat-top cancer treating instrument of new simple and easy pulse generator, make porch steeper, top is more flat, this pulse is better to the therapeutic effect of tumor, more can in the situation that do not injure the normal health cell, effectively to kill malignant cell be cancerous cell or induce its apoptosis.
Technical solution of the present invention is that this therapeutic instrument mainly comprises: power supply, commutator, pulse generator, the electrode with endoscope, oscillograph, medicine CT, B ultrasonic and endoscope, computer and related accessory.
The feature of pulse generator is: comprise two unit that structure is identical, each unit comprises inductance or inducer, electric capacity or capacitor or impulse capacitor, diode and gate-controlled switch or derailing switch.The circuit of each unit is on connected mode: after the negative pole of commutator out-put supply and inductance or electrical equipment and diode are in parallel, one tunnel is in parallel with negative pole and the electrode of electric capacity or capacitor through inductance or inducer, is connected with switch or derailing switch first end after a road is connected with electrode.The second end of switch or derailing switch is connected with the positive pole of commutator out-put supply; It is the second end that an end of inductance is connected to gate-controlled switch, the other end of inductance connects the positive pole of diode, the negative pole of diode connects an end of electric capacity, the other end of electric capacity connects can be by the second end of switch, the be connected positive pole of rear input power as this pulse generator of connection one end of each inductance in two elementary cells, an end separately of the electric capacity in the be connected negative pole of rear input power as this pulse generator of the first end of the gate-controlled switch in two elementary cells, two elementary cells is respectively as outfan and be connected with electrode respectively.
The quantity of gate-controlled switch or derailing switch is included as one or more than two of serial or parallel connection.
Gate-controlled switch maybe can comprise by the device of derailing switch metal-oxide-semiconductor, IGBT pipe, GTO pipe, GTR pipe.
Usefulness of the present invention: can obtain by control the precipitous pulse of flat-top of needed different peak values, the pulse that obtains voltage can exceed input direct voltage, also can be lower than input direct voltage.
Description of drawings
Fig. 1 is the pulse generator basic element circuit figure in the present invention.
Fig. 2 is pulse-generator circuit figure of the present invention.
Fig. 3 is the main oscillogram of pulse generator of the present invention.
Fig. 4 and Fig. 5 are respectively we circuit diagram of pulse generator of the present invention in actual implementing circuit figure.
Fig. 6 is schematic diagram of the present invention.
The specific embodiment
Explain in conjunction with above-mentioned figure, Fig. 6 is schematic diagram of the present invention, comprise casing 11, pulse generator 12, ballast switch or derailing switch 13, electrode 21, oscillograph and electrode connecting line 22, pulse generator input and the electrode connecting line 23 of the gate-controlled switch M1 button keys 15 of commutator 14, pulse generator, the gate-controlled switch M2 button 16 of pulse generator, on and off switch or beginning device 17, starting switch 18, computer and liquid crystal display 19 thereof, oscillograph 20, load load.Casing 11 is the supporting body of upper other each components and parts of mistake, starting switch is connected with mains supply with on and off switch or derailing switch 17 1 ends, one end is connected with the discrepancy of commutator 14, and the outfan of commutator is connected with the input of pulse generator after being connected with starting switch, starting switch and.Computer or its display are connected with on and off switch, ballast switch, starting switch, medicine CT, B ultrasonic, oscillograph one end respectively, and the oscillograph other end is connected with load loadr electrode.During use, after switching on power, start on and off switch, the liquid crystal display display power supply is connected, and mains supply enters commutator, and to advance rectification be unidirectional current, starts rectifier switch, unidirectional current arrives starting switch, opens and starts beginning, and DC current and pulse generator are connected.Press the gate-controlled switch M2 button 16 of the gate-controlled switch M1 button keys 15 of pulse generator or pulse generator and start or close gate-controlled switch or derailing switch M1 or the M2 of pulse generator, the pulse current of pulse generator generation arrives load electrode, the precipitous square-topped pulse that electrode sends, can the kill tumor cell or the apoptosis of inducing tumor cell.Whole process under the imaging guiding of B ultrasonic, medicine CT instrument and endoscope, can be treated accurately to tumor locus.
As depicted in figs. 1 and 2, the present invention includes the identical elementary cell of structure, each unit comprises inductance, electric capacity, diode and gate-controlled switch.It is the second end that an end of inductance is connected to gate-controlled switch, the other end of inductance connects the positive pole of diode, the negative pole of diode connects an end of electric capacity, the other end of electric capacity connects can be by the second end of switch, the be connected positive pole of rear input power as this pulse generator of connection one end of each inductance in two elementary cells, an end separately of the electric capacity in the be connected negative pole of rear input power as this pulse generator of the first end of the gate-controlled switch in two elementary cells, two elementary cells is respectively as outfan and be connected with electrode respectively.Electrode is the electrode of load load.Gate-controlled switch can be one or in series or in parallel with each other more than two and two.Inductance comprises inducer, coupling inductance.
As shown in Figure 3, M1 drives ripple 1, and M2 drives ripple 2, M1 drain-source blood pressure lowering 3, M2 drain-source blood pressure lowering 4, output voltage 5.
Pulse generator charging and discharging process as shown in Figure 4 and Figure 5, after gate-controlled switch or gate-controlled switch device M1 or the driven admittance of M2, inductance (or coupling inductance, inducer) L1 or L2 or magnetize; After M1 or M2 disconnection, because inductive current can not change suddenly, capacitor C 1 or C2 can be recharged and cause capacitor C 1 or C2 voltage to raise; When M2 disconnects and during the M1 admittance, afterflow diode D2 conducting, the voltage of C2 is added on load load and electrode or electrode by M2, obtains a pulse voltage on load load and electrode or electrode; On the contrary, when M1O disconnects and during the M2 admittance, afterflow diode D1 conducting, the voltage of C1 is loaded on load load and electrode or electrode by M1, on load load and electrode or electrode just before a reverse impulse voltage.Leakage inductance or the mutual inductance function of current due to inductance, diode D1 or the quick admittance of D2 meeting, when inductance (mutual inductance or leakage inductance) electric current reaches zero, the backward voltage that D1 or D2 bear C1 or C2 can stop fast, like this time of the rise and fall of the pulse voltage on load load and electrode or electrode very of short duration, the pulse voltage that height of formation is precipitous.Because the voltage pulsation of capacitor C 1 or C2 is very small, the fluctuation of the flat-top of the pulse voltage of load load and electrode or electrode is also very small.

Claims (5)

1.IRE cliffy summit value flat-top cancer treating instrument, it is characterized in that: comprise casing, pulse generator, ballast switch or derailing switch, gate-controlled switch (M2) button of the gate-controlled switch of commutator, pulse generator (M1) button keys, pulse generator, on and off switch or beginning device, starting switch, computer and liquid crystal display, oscillograph, the electrode with endoscope, oscillograph and electrode connecting line, medicine CT, B ultrasonic, pulse generator input and electrode LineCasing is the supporting body of above-mentioned other each components and parts, starting switch is connected with mains supply with on and off switch or derailing switch one end, one end is connected with the input of commutator, after being connected with starting switch, the outfan of commutator is connected with the input of pulse generator, computer and liquid crystal display are connected with endoscope, B ultrasonic, medicine CT, oscillograph one end of on and off switch, ballast switch, starting switch, electrode respectively, and the oscillograph other end is connected with the electrode with endoscope.
2. IRE cliffy summit flat-top cancer treating instrument as claimed in claim 1, it is characterized in that: pulse generator comprise two elementary cells that structure is identical, each unit comprises inductance, electric capacity, diode and gate-controlled switch, one end of inductance is connected to the second end of gate-controlled switch, the other end of inductance connects the positive pole of diode, the negative pole of diode connects an end of electric capacity, the other end of electric capacity connects can be by the second end of switch, the be connected positive pole of rear input power as this pulse generator of connection one end of each inductance in two elementary cells, the be connected negative pole of rear input power as this pulse generator of the first end of the gate-controlled switch in two elementary cells, an end separately of the electric capacity in two elementary cells is respectively as outfan and be connected with electrode respectively.
3. IRE cliffy summit flat-top cancer treating instrument as claimed in claim, it is characterized in that: the quantity of the gate-controlled switch of pulse generator can be one or in series or in parallel with each other more than two and two, and the device of gate-controlled switch comprises metal-oxide-semiconductor, IGBT pipe, GTO pipe, GTR pipe.
4. IRE cliffy summit flat-top cancer treating instrument as claimed in claim 1 is characterized in that inductance comprises inducer, coupling inductance.
5. IRE cliffy summit flat-top cancer treating instrument as claimed in claim 1 is characterized in that the line of its relevant components and parts comprises wire, cable.
CN2012101412029A 2012-05-09 2012-05-09 IRE steep peak flat top cancer therapeutic instrument Pending CN103386165A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2012101412029A CN103386165A (en) 2012-05-09 2012-05-09 IRE steep peak flat top cancer therapeutic instrument

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2012101412029A CN103386165A (en) 2012-05-09 2012-05-09 IRE steep peak flat top cancer therapeutic instrument

Publications (1)

Publication Number Publication Date
CN103386165A true CN103386165A (en) 2013-11-13

Family

ID=49530697

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2012101412029A Pending CN103386165A (en) 2012-05-09 2012-05-09 IRE steep peak flat top cancer therapeutic instrument

Country Status (1)

Country Link
CN (1) CN103386165A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1269250A (en) * 1999-08-23 2000-10-11 北京理化测试技术公司 Electronic insomnia treating instrument
US20030204161A1 (en) * 2002-04-25 2003-10-30 Bozidar Ferek-Petric Implantable electroporation therapy device and method for using same
CN2619667Y (en) * 2003-02-20 2004-06-09 冯尔财 Electronic therapeutic apparatus for prostate gland
CN1596849A (en) * 2004-07-17 2005-03-23 王元知 Cancer treatment instrument

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1269250A (en) * 1999-08-23 2000-10-11 北京理化测试技术公司 Electronic insomnia treating instrument
US20030204161A1 (en) * 2002-04-25 2003-10-30 Bozidar Ferek-Petric Implantable electroporation therapy device and method for using same
CN2619667Y (en) * 2003-02-20 2004-06-09 冯尔财 Electronic therapeutic apparatus for prostate gland
CN1596849A (en) * 2004-07-17 2005-03-23 王元知 Cancer treatment instrument

Similar Documents

Publication Publication Date Title
CN104138638A (en) Erectile dysfunction impact wave therapeutic instrument
CN103585715B (en) Integrated medium frequency current and electric field exciting equipment
CN107714171A (en) A kind of Pulsed Electric Fields therapeutic apparatus for treating tumor
CN105763173B (en) A kind of electric pulse generator
CN101584909A (en) Portable non-invasive neurogenic bladder therapeutic instrument
CN202526774U (en) IRE steep peak square-topped cancer therapeutic instrument
CN103386165A (en) IRE steep peak flat top cancer therapeutic instrument
CN107320842B (en) Low-frequency ultrasonic medicine guide instrument
CN207085077U (en) A kind of portable digital music electro-therapeutic apparatus
CN211675903U (en) Orthogonal electrode circuit for irreversible electroporation ablation in esophagus
CN202605534U (en) Ire cancer therapeutic apparatus
CN102631748A (en) Mobile terminal and electrotherapy method
CN200994989Y (en) High-electric potential therapeutic equipment
CN202355710U (en) An ultrasonic ache treatment apparatus
CN201426840Y (en) Foot massager
CN207575556U (en) A kind of small intelligent health care instrument
CN110464984A (en) The implanted high pressure lesions located in deep brain system transmitted based on wireless energy and data
CN204890759U (en) Automatic medical sausage meat extruder of accuse temperature
CN204073101U (en) Bladder function training instrument
CN114887219B (en) Electric field device for treating tumor
CN209389956U (en) High pressure steep-sided pulse generator
CN102430212A (en) Ultrasonic pain treatment device
CN211584897U (en) Autonomous feedback electronic acupuncture treatment device
CN218420672U (en) Variable wave width's magnetic stimulation circuit
CN105148345A (en) Medical enema machine with automatic temperature control function

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C05 Deemed withdrawal (patent law before 1993)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20131113