CN103349691A - Preparation method of fermentation liquid for antiphlogosis and haemostasis - Google Patents
Preparation method of fermentation liquid for antiphlogosis and haemostasis Download PDFInfo
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- CN103349691A CN103349691A CN2013102255265A CN201310225526A CN103349691A CN 103349691 A CN103349691 A CN 103349691A CN 2013102255265 A CN2013102255265 A CN 2013102255265A CN 201310225526 A CN201310225526 A CN 201310225526A CN 103349691 A CN103349691 A CN 103349691A
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Abstract
The invention discloses a preparation method of a fermentation liquid for antiphlogosis and haemostasis. The preparation method comprises the following steps: mixing flour and pseudo-ginseng powder evenly, and adding composite enzymatic hydrolysate for enzymatic hydrolysis; adding a moderate amount (by percentage) of dry yeast and plant ash into a mixed liquid of the flour and the pseudo-ginseng powder after the enzymatic hydrolysis for fermentation, and extracting a liquid to obtain a fermentation liquid A when a frangrance of mature fermentation can be smelt, namely the fermentation is finished; taking honeysuckle flower, hairyvein agrimony, ramie root and charred human hair for crushing and then sieving, mixing evenly, adding a moderate amount of water, stirring evenly, sterilizing, then adding compound fermentation bacteria liquid brown sugar for anaerobic fermentation, and extracting a liquid to obtain a fermentation liquid B; and evenly mixting the fermentation liquid A and the fermentation liquid B in a certain ratio and then obtaining the fermentation liquid for the antiphlogosis and the haemostasis by concentrating. The fermentation liquid for the antiphlogosis and the haemostasis has the efficacy of strong antiphlogosis and detoxification, quick haemostasis and analgesia and dispersing blood stasis and engendering flesh, and can be used for the treatment of oral ulcer, children injuries caused by knocking, and the like.
Description
Technical field
The present invention relates to a kind of preparation method of fermented liquid, be specifically related to a kind of preparation method of the fermented liquid for anti-inflammation hemostasia.
Background technology
Anti-inflammation hemostasia medicine kind is various in the market, and the medicament composing prescription proportioning is different, and drug effect is different, and many medicines only contain the antiinflammatory composition and do not contain hemostatic compositions, so its haemostatic effect is relatively poor; Some medicines contain hemostatic compositions and do not contain the antiinflammatory composition, though haemostatic effect is arranged, can not prevent well wound inflammation.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, a kind of preparation method with fermented liquid of powerful eliminating inflammation and expelling toxin, quick-acting haemostatic powder pain relieving is provided.
The technical solution used in the present invention is as follows:
A kind of preparation method of the fermented liquid for anti-inflammation hemostasia may further comprise the steps:
(1) take by weighing flour and Radix Notoginseng powder by weight 1:1-2, mix homogeneously adds the complex enzyme hydrolysis liquid that 2-3 doubly measures, and regulates PH to 3-4,35-40 ℃ of heating in water bath 2-3h;
(2) get flour and Radix Notoginseng powder mixing material behind the above-mentioned enzymolysis, add the dryness yeast of 1-1.5% and the plant ash of 1-2%, in 28-30 ℃ of lower open mouth fermentation 3-5d, the fragrance that smells fermenting-ripening namely ferments and finishes, and extracting liq gets fermentation liquid A;
(3) get 4-6 weight portion Flos Lonicerae, 2-3 weight portion Herba Agrimoniae, 3-4 weight portion Radix Boehmeriae, the rear 50-60 of mistake of 1-3 weight portion Crinis Carbonisatus pulverizing mesh sieve, mix homogeneously, add Chinese herbal medicine gross weight 1-2 water doubly, stir, at 100-120 ℃ of lower steam sterilization 10-15min, add the composite zymocyte liquid of Chinese herbal medicine gross weight 10-15% and the brown sugar of 1-2% after the cooling, at 35-38 ℃ of lower anaerobic fermentation 7-10d, extracting liq gets fermentation liquid B;
(4) with fermentation liquid A and the fermentation liquid B ratio mix homogeneously by weight 1-2:1, be concentrated into the 1/6-1/4 of original volume, namely get the fermented liquid for anti-inflammation hemostasia.
The described complex enzyme hydrolysis liquid of step (1) is to add water by 0.02-0.03% cellulase, 0.03-0.04% pectase, 0.02-0.04% protease to be composited.
The described composite zymocyte liquid of step (3) is the strain by following weight portion: 5-10 part Bacillus licheniformis, 2-5 part bacillus subtilis, 4-6 part Bafillus natt, 5-8 part bacillus acidophilus, 3-6 part are had a liking for acetobacter xylinum, 2-4 part saccharomyces cerevisiae, 5-10 part aspergillus oryzae and are composited after cultivating.
Beneficial effect of the present invention:
The fermentation liquid that utilizes flour and Radix Notoginseng powder fermentation to make in the present invention's prescription has the effect of eliminating inflammation and expelling toxin, the anti-inflammation hemostasia effect of gold conjugate Flos Lonicerae, Herba Agrimoniae, Radix Boehmeriae, four kinds of Chinese herbal medicine fermented liquids of Crinis Carbonisatus, make it the effect that fermented liquid of the present invention has powerful eliminating inflammation and expelling toxin, quick-acting haemostatic powder pain relieving, blood stasis dispelling granulation promoting, overcome existing not antiinflammatory of drug hemostasis, the shortcoming that antiinflammatory is not stopped blooding, can be used for the treatment of oral ulcer, and children's's gouge etc.
The specific embodiment
A kind of preparation method of the fermented liquid for anti-inflammation hemostasia may further comprise the steps:
(1) take by weighing flour and Radix Notoginseng powder by weight 1:2, mix homogeneously, the complex enzyme hydrolysis liquid of 3 times of amounts of adding is regulated PH to 3,40 ℃ of heating in water bath 2h;
(2) get flour and Radix Notoginseng powder mixing material behind the above-mentioned enzymolysis, add 1.2% dryness yeast and 1.5% plant ash, in 28 ℃ of lower open mouths fermentation 4d, the fragrance that smells fermenting-ripening namely ferments and finishes, and extracting liq gets fermentation liquid A;
(3) get 5 weight portion Flos Loniceraes, 3 weight portion Herba Agrimoniaes, 3 weight Radix Boehmeriaes, rear 50 mesh sieves of crossing of 2 weight Crinis Carbonisatus pulverizing, mix homogeneously, the water that adds 1.5 times of Chinese herbal medicine gross weights, stir, at 110 ℃ of lower steam sterilization 10min, add the composite zymocyte liquid of Chinese herbal medicine gross weight 10% and 2% brown sugar after the cooling, at 37 ℃ of lower anaerobic fermentation 8d, extracting liq gets fermentation liquid B;
(4) with fermentation liquid A and the fermentation liquid B ratio mix homogeneously by weight 1.5:1, be concentrated into 1/5 of original volume, namely get the fermented liquid for anti-inflammation hemostasia.
The described complex enzyme hydrolysis liquid of step (1) is to add water by 0.02% cellulase, 0.03% pectase, 0.03% protease to be composited.
The described composite zymocyte liquid of step (3) is the strain by following weight portion: 8 parts of Bacillus licheniformis, 4 parts of bacillus subtilises, 5 parts of Bafillus natt, 6 parts of bacillus acidophilus, 4 parts have a liking for acetobacter xylinum, 2-4 part saccharomyces cerevisiae, 7 parts of aspergillus oryzaes and after cultivating, be composited.
During use fermentation liquid is sprayed on the wound and can plays the anti-inflammation hemostasia effect.
Case 1: Lee, 15 years old, hands was damaged, and wound, hemorrhage is arranged, and spilt medicinal liquid of the present invention, hemostasis then and there, medicine for external use is wrapped up with gauze, the second day wound healing.
Case 2: Lin, 39 years old, the sanitationman, hands is scratched by reinforcing bar, and nearly 1 centimetre of wound is arranged, and is hemorrhage, spills medicinal liquid of the present invention, hemostasis then and there, medicine for external use is wrapped up with gauze, and second day is changed dressings, the 3rd day wound healing.
Case 3: the Wang, 58 years old, the sanitationman, hands is scratched by guardrail, and is hemorrhage, spills medicinal liquid of the present invention, hemostasis then and there, medicine for external use is wrapped up with gauze, the second day wound healing.
Claims (3)
1. preparation method that is used for the fermented liquid of anti-inflammation hemostasia is characterized in that may further comprise the steps:
(1) take by weighing flour and Radix Notoginseng powder by weight 1:1-2, mix homogeneously adds the complex enzyme hydrolysis liquid that 2-3 doubly measures, and regulates PH to 3-4,35-40 ℃ of heating in water bath 2-3h;
(2) get flour and Radix Notoginseng powder mixing material behind the above-mentioned enzymolysis, add the dryness yeast of 1-1.5% and the plant ash of 1-2%, in 28-30 ℃ of lower open mouth fermentation 3-5d, the fragrance that smells fermenting-ripening namely ferments and finishes, and extracting liq gets fermentation liquid A;
(3) get 4-6 weight portion Flos Lonicerae, 2-3 weight portion Herba Agrimoniae, 3-4 weight portion Radix Boehmeriae, the rear 50-60 of mistake of 1-3 weight portion Crinis Carbonisatus pulverizing mesh sieve, mix homogeneously, add Chinese herbal medicine gross weight 1-2 water doubly, stir, at 100-120 ℃ of lower steam sterilization 10-15min, add the composite zymocyte liquid of Chinese herbal medicine gross weight 10-15% and the brown sugar of 1-2% after the cooling, at 35-38 ℃ of lower anaerobic fermentation 7-10d, extracting liq gets fermentation liquid B;
(4) with fermentation liquid A and the fermentation liquid B ratio mix homogeneously by weight 1-2:1, be concentrated into the 1/6-1/4 of original volume, namely get the fermented liquid for anti-inflammation hemostasia.
2. the preparation method of a kind of fermented liquid for anti-inflammation hemostasia according to claim 1, it is characterized in that, the described complex enzyme hydrolysis liquid of step (1) is to add water by 0.02-0.03% cellulase, 0.03-0.04% pectase, 0.02-0.04% protease to be composited.
3. the preparation method of a kind of fermented liquid for anti-inflammation hemostasia according to claim 1, it is characterized in that, the described composite zymocyte liquid of step (3) is the strain by following weight portion: 5-10 part Bacillus licheniformis, 2-5 part bacillus subtilis, 4-6 part Bafillus natt, 5-8 part bacillus acidophilus, 3-6 part are had a liking for acetobacter xylinum, 2-4 part saccharomyces cerevisiae, 5-10 part aspergillus oryzae and are composited after cultivating.
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| CN201310225526.5A CN103349691B (en) | 2013-06-07 | 2013-06-07 | A kind of preparation method of the fermented liquid for anti-inflammation hemostasia |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104178517A (en) * | 2014-08-19 | 2014-12-03 | 云南中烟工业有限责任公司 | Lonicera japonica fermented extract and preparation method and application thereof |
| CN106376921A (en) * | 2016-08-29 | 2017-02-08 | 彭展忠 | Cough-relieving ferment and manufacturing method thereof |
| CN108578592A (en) * | 2018-06-13 | 2018-09-28 | 浙江大飞龙动物保健品股份有限公司 | Prevent the preparation and preparation method thereof of hog cholera |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101837099A (en) * | 2010-07-01 | 2010-09-22 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for curing intermenstrual bleeding and preparation method thereof |
-
2013
- 2013-06-07 CN CN201310225526.5A patent/CN103349691B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101837099A (en) * | 2010-07-01 | 2010-09-22 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for curing intermenstrual bleeding and preparation method thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104178517A (en) * | 2014-08-19 | 2014-12-03 | 云南中烟工业有限责任公司 | Lonicera japonica fermented extract and preparation method and application thereof |
| CN106376921A (en) * | 2016-08-29 | 2017-02-08 | 彭展忠 | Cough-relieving ferment and manufacturing method thereof |
| CN108578592A (en) * | 2018-06-13 | 2018-09-28 | 浙江大飞龙动物保健品股份有限公司 | Prevent the preparation and preparation method thereof of hog cholera |
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| CN103349691B (en) | 2015-11-25 |
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Address after: 246600 Changning Industrial Zone, Yuexi County, Anqing, Anhui Patentee after: Anqing Hui must pharmaceutical Limited by Share Ltd Address before: 246600 Changning Industrial Zone, Yuexi County, Anqing, Anhui Patentee before: Anqing Chengfeng Pharmaceutical Co.,Ltd. |
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