CN103316193B - Medical protective paint and preparation method thereof - Google Patents

Medical protective paint and preparation method thereof Download PDF

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Publication number
CN103316193B
CN103316193B CN201310197835.6A CN201310197835A CN103316193B CN 103316193 B CN103316193 B CN 103316193B CN 201310197835 A CN201310197835 A CN 201310197835A CN 103316193 B CN103316193 B CN 103316193B
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protective paint
medical protective
yoghourt
parts
fruit
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Expired - Fee Related
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CN201310197835.6A
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CN103316193A (en
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钟德芹
吴春子
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Individual
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Abstract

The invention discloses a medical protective paint and a preparation method thereof. The medical protective paint is prepared from 100-200 parts of red tomato fruits, 30-60 parts of yoghourt and 30-60 parts of aloe vera gel. The preparation method comprises: boiling the red tomato fruits in water and breaking the red tomato fruits into a thick liquid, adding the yoghourt and stirring the mixed thick liquid, and adding the aloe vera gel after filtration. The medical protective paint is mainly used in pharmacy intravenous admixture services, and is suitable for people who frequently contact cytotoxic drugs such as anti-cancer drugs and the like. The medical protective paint can be directly smeared on exposed skins, drugs in environment are prevented from directly contacting skins and being absorbed by skins, the immunity of human bodies can be enhanced, and the medical protective paint has the effects of protecting skins and beautifying features when being absorbed by human bodies.

Description

Medical protective paint and preparation method thereof
Technical field
The invention belongs to Medical protective products technical field, especially relate to medical protective paint of a kind of Medical Personnel Protection and preparation method thereof.
Background technology
At present, many hospitals establish Pharmacy Intravenous Admixture Service, by medicine centralized configuration in the clean environment of relative closure.But many cancer therapy drugs are cytotoxic drug, there is very strong aberration inducing or carcinogenesis.When configuring these medicines, under pressure of the inside of a bottle crossing high situation when extracting syringe needle after having the ampoule of drug powder or bottled medicinal liquor and extracting, when syringe needle comes off in operating process, when changing liquid, all can cause drug particle and overflow or spill.These overflows are often present in surrounding with the form of microgranule, and fly away everywhere, are easy to and enter Pharmaceutical setting personnel human body by skin, eyes, oral cavity, endanger the personnel health that makes up a prescription.For these overflows in the configuration of minimizing cytotoxic drug are to the harm of human body, medical personnel take to wear the safeguard procedures such as glove, mask, but because overflow microgranule exists with the form of aerosol, these measures are difficult to block itself and the contact configuring the area skin such as personnel face, hand completely.Have report, pharmacy staff and the nurse contacting cisplatin of exposing cell drug toxicity, the content finding that there is platinum in clastogenic TAI535 cell and urine in its urine respectively obviously increases.Long Term Contact cytotoxic drug, can cause compromised immune, and health is tired, resistance decline, flu, alopecia, insomnia, energy are not concentrated, menoxenia etc.Pharmacy Intravenous Admixture Service is again the environment of relative closure, staff works every day for a long time in this environment, be exposed to frequently and have in the environment of cytotoxic drug, be not only faced with the hazards of medication of reality, and bring heavy mental pressure to staff.Existingly wear the safeguard procedures such as mask and glove, can only block the partial portion such as oral cavity and palm, other skin exposed can not get protection.And these hazardous particles flown away are once run into skin, are easy to attachment, and are absorbed by the body, work the mischief.
Summary of the invention
The technical problem to be solved in the present invention is to provide one and effectively can blocks exposure portion skin and be sticky with hazardous particle, simultaneously can the medical protective paint improving human immunologic function and preparation method thereof.
For solving the problems of the technologies described above, the present invention is made up of the raw material of following weight portion: Fructus Lycopersici esculenti fruit 100 ~ 200 parts, Yoghourt 30 ~ 60 parts, Aloe glue 30 ~ 60 parts; After described Fructus Lycopersici esculenti fruit boils in 50 ~ 60 degree of water, broken pulping.
Preferably be made up of the raw material of following weight portion: Fructus Lycopersici esculenti fruit 120 ~ 180 parts, Yoghourt 40 ~ 50 parts, Aloe glue 40 ~ 50 parts.
The preparation method of medical protective paint of the present invention, comprises the following steps:
A, take Fructus Lycopersici esculenti fruit, Yoghourt, Aloe glue by formula ratio;
B, get after Fructus Lycopersici esculenti fruit boils 20 ~ 30 minutes in 50 ~ 60 degree of water, by broken for fruit pulping;
C, in above-mentioned strained tomatoes, add Yoghourt, stir 5 ~ 10 minutes;
D, be that the filter screen of 0.5 millimeter filters above-mentioned mixture slurry with aperture, collect filtrate;
E, in above-mentioned filtrate, add Aloe glue, then stir 2 ~ 3 minutes, keep in Dark Place under 4 ~ 10 degree.
After preferably described Fructus Lycopersici esculenti fruit boils 25 ~ 30 minutes in 58 ~ 60 degree of water, carry out crushing and beating immediately while hot.
Described Yoghourt is clabber, namely adds clabber, stir 6 to 8 minutes again after pulping while fruit fragmentation.
The present invention is processed by Fructus Lycopersici esculenti fruit, Yoghourt and Aloe glue.The lycopene that enriches contained in Fructus Lycopersici esculenti is one of most powerful antioxidant be found in current natural plant; it has the ability of extremely strong scavenging free radicals; immunity, Cell protection DNA can be improved from free radical damage; block histiocyte, under the effect of extraneous mutagenic agent, gene variation occurs, play and prevent cytopathy, sudden change, canceration effect.Meanwhile, lycopene invades the free radical of human body by quencher, forms one natural cover for defense, can effectively stop extraneous ultraviolet, radiation to the injury of skin in skin surface.Yoghourt is fermented by pure milk and forms, and after fermentation except the whole nutritional labelings remaining fresh milk, in milk, sugar, protein have about 20% to be hydrolyzed into as little molecule, and the comparable raw material milk of fatty acid increases by 2 times.Lycopene in Tomatoes and Yoghourt can both directly spread upon on skin, are human body percutaneous absorption, and do not damage skin.
Lycopene is present in the chromoplast of cell, and Fructus Lycopersici esculenti is through heating and making beating, and the lycopene in its cell can be discharged in a large number, content of lycopene comparatively room temperature squeezing showed increased in juice.Meanwhile, lycopene is fat-soluble pigment, add Yoghourt and stir after, in Yoghourt, fatty acid is fractured into less Oil globule, adds the surface area of Oil globule, and then can improve the stripping quantity of lycopene further.Lycopene is dissolved in Yoghourt fat, can prevent lycopene from contacting oxygen and degrading when depositing, and is conducive to keeping lycopene active.Aloe glue has astriction, and it effectively can pin moisture, active cell vigor.It is coated in energy fast filming after on skin, makes skin solid careful.Tamato fruit adds hot breakdown process, more jointly stirs with Yoghourt, and in tamato fruit, the effective ingredient of lycopene isoreactivity material and Yoghourt obtains and farthest extracts and retain.After filtered juice and Aloe glue mix and blend, repaste and be put on skin, utilize convergence and the fixation of Aloe glue, it can be made to be attached to skin surface fast, form the protecting film that one deck has biological activity and smooth in appearance.This protecting film can absorb for skin on the one hand, and improve body high immunity, Cell protection DNA is from infringement.Meanwhile, it plays buffer action, and the contact of skin capable of blocking harmful substance directly and in environment, reduces the risk of being encroached on.Pharmacy Intravenous Admixture Service personnel configure cytotoxic drug time, can first by this protective agent uniform application outside the exposure portion skin such as hand, face, and then wear glove, mask carries out disposition.Under same environmental condition, through the same long time, repeatedly left drug in same people's face sanitizer is detected.After testing, use after protective agent, its face sanitizer drug content, higher than amount when not using protective agent, although illustrate that medicine can be attached on protective agent, receives blocking-up, is not rapidly absorbed into skin.Group experiment finds, the personnel of every use protective agent, and its index such as skin appearance and elasticity, significantly better than matched group, uses the personnel of protective agent, and its urine leaf detects that the ratio of ingredient is starkly lower than matched group ratio.
Detailed description of the invention
Embodiment 1
Get ripe Fructus Lycopersici esculenti fruit 100 grams, clabber 30 grams, 30 grams, Aloe vulgaris glue respectively, process as follows:
A, get Fructus Lycopersici esculenti fruit 100 grams, put into 50-55 degree water after washing and boil 30 minutes, the practical beater of consequence will be heated by its broken pulping;
Add clabber 30 grams in b, the strained tomatoes produced in step a, utilize agitator to stir 5 minutes;
C, be that the stainless steel filtering net of 0.5 millimeter filters the mixture slurry that step b produces with aperture, collect filtrate with vial;
D, in filtrate, add Aloe glue 30 grams, then stir 2 to 3 minutes, and it is for subsequent use to keep in Dark Place under 4 to 10 degree.
Produce protection varnish after adding Aloe glue can use immediately, also coldly can deposit rear use, but preferably be finished in 1 week.Fresh fruit ripe more than tamato fruit preferably uses 9 one-tenth, Yoghourt can use milk or sheep milk to make, and Aloe glue is Curacao or the Chinese aloe aloe making of trophophase 2-3.The concrete using method of protection varnish is: before staff enters Pharmacy Intravenous Admixture Service, get a certain amount of protection varnish and be directly coated on face cervical region and hand skin, and repeatedly wipes even with hands, makes it form the film of continuous uniform at skin surface; Cleaned with water before leaving offices, the effect stoping medicine to be infected with skin and enhancing human body immunity power can be played.
The personnel configuring cancer therapy drug and cisplatin in Pharmacy Intravenous Admixture Service be divided into 2 batches of groups to test, wherein 1 group of protection varnish using the present embodiment to produce, another group is matched group.After 1 month, all personnel's urine is detected.Result detects in urine that the personnel ratios of drug residue is: test group 15%, and matched group is 31%, and protection varnish protection effect is obvious.
Embodiment 2
The present embodiment is processed as follows by ripe Fructus Lycopersici esculenti fruit 120 grams, clabber 40 grams, 40 grams, Aloe vulgaris glue:
A, get Fructus Lycopersici esculenti fruit 120 grams, put into 55-58 degree water after washing and boil 20 minutes, after heating fruit immediately with beater by its broken pulping;
Add clabber 40 grams in b, the strained tomatoes produced in step a, utilize ultrasonic stirrer to stir 6 minutes;
C, be that the stainless steel filtering net of 0.5 millimeter filters the mixture slurry that step b produces with aperture, collect filtrate with vial;
D, in filtrate, add Aloe glue 40 grams, then stir 2 to 3 minutes, and it is for subsequent use to keep in Dark Place under 4 to 10 degree.
Embodiment 3
The present embodiment is processed as follows by ripe Fructus Lycopersici esculenti fruit 180 grams, clabber 50 grams, 50 grams, Aloe vulgaris glue:
A, get Fructus Lycopersici esculenti fruit 180 grams, put into 60 degree of water after washing and boil 25 minutes, in fruit, add clabber 50 grams after the heating, with beater by its broken pulping;
B, the mixing slurry stirring of step a being produced with agitator 8 minutes;
C, be that the stainless steel filtering net of 0.5 millimeter filters the mixture slurry that step b produces with aperture, collect filtrate with vial;
D, in filtrate, add Aloe glue 50 grams, then stir 2 to 3 minutes, and it is for subsequent use to keep in Dark Place under 4 to 10 degree.
Heating can improve the content of lycopene in Fructus Lycopersici esculenti juice, but superheated, the cis isomeric of lycopene can be promoted again, therefore the heating-up temperature of the present embodiment adopts 60 degree, both can improve the content of lycopene in Fructus Lycopersici esculenti juice, and be unlikely to again to make a large amount of lycopene transisomers become cis.For reducing lycopene thermal degradation, after tamato fruit can being shredded, quickly heat up to 60 degree with microwave-oven-heating, then process of pulling an oar.Fructus Lycopersici esculenti and Yoghourt stir jointly simultaneously, utilize the effect of fatty acid in Yoghourt, also can promote to utilize lycopene to enter in juice.With above-mentioned protection varnish test of producing, the personnel configuring aberration inducing cancer therapy drug and cisplatin in Pharmacy Intravenous Admixture Service are divided into 2 batches of groups, wherein 1 group uses above-mentioned varnish, and another group is matched group.After 1 month, all personnel's urine is detected.Detect in urine that the ratio of drug residue is test group 13%, matched group is 30%.External observation, test group personnel face and hand skin outward appearance and elasticity are significantly better than matched group.
Embodiment 4
The present embodiment is processed as follows by ripe Fructus Lycopersici esculenti fruit 200 grams, clabber 60 grams, 60 grams, Aloe vulgaris glue:
A, get Fructus Lycopersici esculenti fruit 200 grams, put into 60 degree of water after washing and boil 30 minutes, the practical beater of consequence will be heated by its broken pulping;
Add clabber 60 grams in b, the strained tomatoes produced in step a, utilize agitator to stir 10 minutes;
C, be that the stainless steel filtering net of 0.5 millimeter filters the mixture slurry that step b produces with aperture, collect filtrate with vial;
D, in filtrate, add Aloe glue 60 grams, then stir 2 to 3 minutes, and it is for subsequent use to keep in Dark Place under 4 to 10 degree.
This mixing juice contains multiple natural bioactivity substance, is very easily absorbed by the body, can not only enhancing human body immunity power, but also has beauty treatment and skin care effect.Lycopene also invades the free radical of human body by quencher, form barrier, stop extraneous ultraviolet, radiation to the injury of skin in skin surface, and therefore, the medical worker that this juice also can be used for being engaged in perspective work does protective agent use.

Claims (5)

1. a medical protective paint, is characterized in that being made up of the raw material of following weight portion: Fructus Lycopersici esculenti fruit 100 ~ 200 parts, Yoghourt 30 ~ 60 parts, Aloe glue 30 ~ 60 parts; After described Fructus Lycopersici esculenti fruit boils in 50 ~ 60 degree of water, broken pulping.
2. medical protective paint according to claim 1, is characterized in that being made up of the raw material of following weight portion: Fructus Lycopersici esculenti fruit 120 ~ 180 parts, Yoghourt 40 ~ 50 parts, Aloe glue 40 ~ 50 parts.
3. the preparation method of medical protective paint according to claim 1 and 2, is characterized in that comprising the following steps:
A, take Fructus Lycopersici esculenti fruit, Yoghourt, Aloe glue by formula ratio;
B, get after Fructus Lycopersici esculenti fruit boils 20 ~ 30 minutes in 50 ~ 60 degree of water, by broken for fruit pulping;
C, in above-mentioned strained tomatoes, add Yoghourt, stir 5 ~ 10 minutes;
D, be that the filter screen of 0.5 millimeter filters above-mentioned mixture slurry with aperture, collect filtrate;
E, in above-mentioned filtrate, add Aloe glue, then stir 2 ~ 3 minutes, keep in Dark Place under 4 ~ 10 degree.
4. the preparation method of medical protective paint according to claim 3, after it is characterized in that described Fructus Lycopersici esculenti fruit boils 25 ~ 30 minutes in 58 ~ 60 degree of water, carries out crushing and beating while hot immediately.
5. the preparation method of medical protective paint according to claim 3, is characterized in that described Yoghourt is clabber, namely adds clabber, stir 6 to 8 minutes again after pulping while fruit fragmentation.
CN201310197835.6A 2013-05-25 2013-05-25 Medical protective paint and preparation method thereof Expired - Fee Related CN103316193B (en)

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Application Number Priority Date Filing Date Title
CN201310197835.6A CN103316193B (en) 2013-05-25 2013-05-25 Medical protective paint and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310197835.6A CN103316193B (en) 2013-05-25 2013-05-25 Medical protective paint and preparation method thereof

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CN103316193A CN103316193A (en) 2013-09-25
CN103316193B true CN103316193B (en) 2015-04-01

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