CN103284762A

CN103284762A - Device for sampling organ

Info

Publication number: CN103284762A
Application number: CN2012100438638A
Authority: CN
Inventors: R·赞贝利
Original assignee: STERYLAB Srl
Current assignee: STERYLAB Srl
Priority date: 2012-02-24
Filing date: 2012-02-24
Publication date: 2013-09-11

Abstract

The invention discloses a sampling device (1) which comprises a cannula (2) on the outside, a plate component (4) and a stylet (7), wherein an opening (21) is formed in the cannula and provided with a cutting edge (27) which is used for slicing a sample inside an organ; the plate component can glidingly mounted in the cannula (2), and a semicircular cylinder part (41) is formed in a far end of the plate component; the stylet (7) is glidingly mounted in the plate component (4), and a tip end (70) is formed in the stylet (7) and protrudes out of the opening of the cannula (2) to puncture the outside of the organ; a narrowing part (23) is formed inside the opening (21) of the cannula (2); at least one pair of circumferentially and relatively arranged and grouped teeth (42 and 43) is formed in the far end of the semicircular cylinder part (41) of the plate component and suitable for radially inwards bending when encountering the narrowing part (23) of the opening, so that a base part of the cut sample is firmly grasped, and the sample is allowed to be taken out by means of the plate component (4); and simultaneously, the cannula (2) is kept in a working position, thereby allowing marrow or blood to be extracted after the sample is taken out.

Description

The device that organ is taken a sample

Technical field

The present invention relates to the field of taking a sample with soft tissue to hard.

In brief, sampling comprises and sampled in the inside of organ, with the character of the disease of the cell of finding organ and/or (at cell in each maturation period) organ.

Background technology

Knownly on the market be suitable for taking out the sample of soft and hard tissue to be used for the various types of this device of laboratory diagnosis test subsequently.

These devices generally include the tubular shell with mouth sharp-pointed, cutting, have arranged the core components or the stylet that are provided with perforation tips in mouth, and perforation tips is from the outstanding outside with the puncture organ of the mouth of sleeve pipe.In case the tip of stylet penetrates the outside, then stylet takes out and sleeve pipe advances and enters organ from sleeve pipe, to cut sample in the mouth of sleeve pipe.This moment, the doctor carried out the oscillating motion of sleeve pipe so that the base portion fracture (dislocation) of the sample that will be removed.Sleeve pipe takes out from organ subsequently, and the sample that is cut is carried in the sleeve pipe.At last, taking out the mouth that rod (probe) is inserted into sleeve pipe promotes the sample that is removed and makes it discharge apparatus with the rear portion to sleeve pipe.

This device has multiple shortcoming.Main shortcoming be owing to when great amount of samples along with sleeve pipe has lost a large amount of samples when patient takes out the mouth skid off sleeve pipe.

Another shortcoming namely, sometimes, is being collected outside the sample by following true the description, and the doctor must sample to marrow (blood) in organ.In current device, this blood sampling must forcibly carry out before the cutting sample, otherwise the sample of previous cutting will block the mouth of sleeve pipe, stop the suction of marrow.As a result, Zhi Bei sample will lose blood cell subsequently, and blood cell is important for diagnostic check.As a result, the doctor must carry out two independent samplings through two different apparatuses commonly used: one is used for the marrow sampling and another is used for specimen sample.

For at least part of shortcoming that overcomes sample losses, the sleeve pipe with mouth of truncated cone is known in market.By this way, by the cylindrical sample that cuts of cutting edge of the mouth of sleeve pipe, because the dislocation motion, on the conical inboard wall that rests on mouthful and be arranged to have the axis that the axis with respect to mouth tilts, thereby the space that occupies is greater than the outlet diameter of mouth, thereby avoided falling by the hole in the mouth.

But this system does not avoid the loss of sample fully.In addition, because cone point (it has increased the diameter of sleeve pipe) reaches 4-5mm or bigger and make the base portion fracture of the sample motion of will dislocating usually, so this is proved to be that invasive, traumatogenic and painful process is arranged very much for patient.

United States Patent (USP) 5,333,619 under the Burgio name has been described plate shape device, and it has the semi-cylindrical shaped tip, is called plate member later on.After thereby the base portion of sample was cut off in dislocation, plate member was inserted into the sleeve pipe with bell.The bent at its tip of plate member, thus run into sleeve pipe the mouth tapered wall and be wedged in sample and mouthful wall between, avoid the loss of sample.But, adopt this plate member device, the loss of sample is not eliminated fully.In addition, plate member is inserted the biopsy sleeve pipe sometimes can promote sample, makes sample damage or makes sample become fragment.

The replacement scheme of plate member device is disclosed in WO95/18568 (Medsol), it has described the inner sleeve with spiral terminal, be tensioned when being in traction state spiral terminal of following time, thereby the sample that promptly is cut in the mouth of trocar sheath and permission spiral terminal are separated.There are some shortcomings in this device, and main cause is because the extruding sample of coil is damaged and in order to ensure the necessary space of built-in system, trocar sheath has increased external diameter to be caused patient is caused bigger damage.

In order to reduce for patient's damage and to avoid damaging sample, such biopsy apparatus is known, for example described in EP 1210911 (Islam) and the EP 1277440 (Zambelli), they provide the columnar mouth that has less than the internal diameter of casing inner diameter, to limit the edge of energy retain sample.

In any case, all said apparatus all are arranged to take out the trocar sheath that has the sample that obtains from the operating position.

Motion multiple solution simultaneously trocar sheath is stayed put to allow sample to be moved out of from the mouth of trocar sheath.

WO 96/27330 (Rubistein) has described the plate member that is provided with two vertical alar parts in the tip, and vertically alar part is crooked to firmly grasp sample in the bell of sleeve pipe.

WO 00/10465 has described plate member, and plate member is provided with the tip of band slit, to improve its elasticity of flexure.When the tip of plate member ran into the bell of sleeve pipe, the tip of plate member narrowed down to firmly grasp sample.

EP 1136039 has described plate member, and plate member is provided with the tip that has narrowed portion, as hinges, with bending when contact with the tapered wall of the mouth of sleeve pipe, is suitable for claw that the part of sample is sampled thereby form.

These solutions produce result badly very, because they have damaged sample, and make the sample distortion with respect to its drum, and they can not firmly grasp securely sample or they only allow from sleeve portion shift out sample.In addition, this has hinted to have following problem owing to be provided with cone ports and have the dislocation action, except carrying out operation bidirectional to take out the sample that is sampled from sleeve pipe with probe, patient has been caused bigger damage.

Summary of the invention

Target of the present invention is by providing safe, reliable and making patient's biopsy of bone's device injury-free or infringement overcome the shortcoming of prior art.

Another target of the present invention provides such device, and described device can carry out the sampling of the sample of osseous tissue, and does not make sample damage.

Another target of the present invention provides such device, and described device allows when taking out sample sleeve pipe to be stayed put, thereby allows after the cutting sample but not carry out the suction of marrow before cutting sample.

Another target of the present invention provides such device, and described device is compact and is simply and fast for the doctor uses.

These targets have been realized according to the present invention with feature listed in the appended independent claims 1.

Become obvious according to dependent claims the preferred embodiments of the present invention.

After this, the term near-end will be used to identify the part of the person's that is expressed as the oriented manipulation device, and the term far-end is designated as towards the part of patient's device during being illustrated in described process.

Sampler according to the present invention comprises:

● outside sleeve pipe, the sleeve pipe of described outside are provided with mouth with cutting edge with the sample of the inside of cutting organ,

● plate member, described plate member be slidably mounted in the described sleeve pipe and its far-end be provided with the semicircular cylinder part and

● stylet (perhaps core components), described stylet (perhaps core components) are slidably mounted in the described plate member and are provided with from the outstanding tip of the mouth of described sleeve pipe with the described outside of puncturing.

The mouth of the described sleeve pipe semicircular cylinder part of portion with narrowed portion and described plate member within it has at least one pair of circumferentially relative tooth in groups at its far-end, described tooth is suitable for radially curving inwardly when the narrowed portion that runs into described mouthful, with the base portion of the sample that promptly is cut and allow to utilize described plate member to take out sample, simultaneously sleeve pipe is remained on the operating position.

Description of drawings

With reference in the accompanying drawings shown, be exemplary thereby be nonrestrictive embodiment that by detailed description subsequently, it is more clear that further feature of the present invention will become fully, wherein:

Fig. 1 is the side view that illustrates according to three parts of the decomposition of biopsy apparatus of the present invention;

Fig. 2 is the axial section that amplifies, and the mouth of sleeve pipe of the device of Fig. 1 is shown;

Fig. 3 is the axial section of handpiece of the device of Fig. 1;

Fig. 4 is perspective view, and the part of far-end of plate member of the device of partial graph 1 is shown;

Fig. 5 is the amplification axial section of far-end of the plate member of Fig. 4;

Fig. 6 is the figure from the back of the support member of the plate member of the device of Fig. 1 (observation);

Fig. 7 and 8 is respectively along the cross-sectional plane VII-VII of Fig. 6 and two profiles of VIII-VIII intercepting;

Fig. 9 is the figure of the back (observation) of the breech lock installed from the support member of the plate member of the device of Fig. 1;

Figure 10 and 11 is respectively along the cross-sectional plane X-X of Fig. 9 and two profiles of XI-XI intercepting;

Figure 12 is the profilograph of support member of stylet of the device of Fig. 1;

Figure 13 is the cross-sectional view strength along the section XIII-XIII intercepting of Figure 12;

Figure 14 is the side view of the device of assembled Fig. 1, is in the position of the organ that is ready to puncture;

Figure 15 is the enlarged drawing at tip of the device of Figure 14, mouthful being illustrated with axial section of its middle sleeve;

Figure 16 is the side view of the device of Figure 14, and wherein stylet has been removed and has activated for the sample of collecting organ or the plate member of core;

Figure 17 is the enlarged drawing at tip of the device of Figure 16, mouthful being illustrated with axial section of its middle sleeve; And

Figure 18 is the side view of the device of Figure 16, and wherein plate member has been removed and has been attached (under the situation of needs) for the syringe of collecting marrow or blood sample.

The specific embodiment

Device for sampling and extraction marrow or blood according to the present invention is represented with Reference numeral 1 as a whole, and is described with reference to the accompanying drawings.

With reference now to Fig. 1,, device 1 comprises: outside sleeve pipe 2; Plate member 4, plate member 4 are suitable for axially inserting in the sleeve pipe 2; With stylet or core components 7, stylet or core components 7 are suitable for axially inserting plate member 4.

The near-end of sleeve pipe 2 is fixed to handpiece 3.The near-end of plate member 4 is fixed to support member 5, at support member breech lock 6 is installed.The near-end of stylet 7 is fixed to sealing support member 8.

Sleeve pipe 2 comprises cylindrical metal pipe 20, and managing 20 inside is hollow, to limit axial pipeline 25 (Fig. 2).Go out as shown in FIG. 2, the pipe 20 of sleeve pipe has external diameter Φ 1 and internal diameter Φ 2.

Mouthfuls 21 are fixed on the edge of far-end of pipe 20 of sleeve pipe by laser weld portion 22.Mouth 21 has the drum of hollow to limit axial cavity 26.Mouth 21 has external diameter Φ 3, internal diameter Φ 4 and length L 1.

The external diameter Φ 3 of mouth 21 equals the external diameter Φ 1 of the pipe 20 of sleeve pipe.On the other hand, the internal diameter Φ 4 of mouth 21 is slightly less than the internal diameter Φ 2 of the pipe 20 of sleeve pipe.By this way, narrowed portion is limited at from managing 20 pipeline 25 to the passage in the chamber 26 of mouth 21.The near-end of mouth 21 has by the part 23 of suitably enlarging.By this way, the narrowed portion between the mouth 21 of the pipeline 25 of pipe 20 and sleeve pipe is defined by short conical transition zone 23.

Mouth 21 has remote edge 27, and remote edge 27 has suitable tapering to become sharp-pointed and to have cutting can penetrate organ.Mouthful cutting edge 27 have profile with a plurality of adjacent circular arcs, can scrape and cut a plurality of most advanced and sophisticated 28 of bone to limit.The total length L 1 of mouth 21 is about 2-3mm.

With reference to figure 1 and 3, handpiece 3 has cylindrical shape tang 30, and by common mode or other method bonding, plastic material, the pipe 120 of metal is fixed in the tang 30, and the proximal part of the pipe 20 of sleeve pipe is welded in the pipe 120.Luer Lock (revolving lock interface) type tapered coupling 31 is arranged in the near-end of tang 30 of handpiece.Tapered coupling 31 has two radially alar parts 31 ', and radially alar part 31 ' is arranged in along on the relative position of diametric(al), plays the work of screw thread in order to allow the tip of medical apparatus and instruments, for example is used for extracting the syringe of marrow or blood, is screwed on.

Should be noted that Luer lock (Luer Lock) cone 31 is by direct molded acquisition the in handpiece 3.For this purpose, leave two side openings 131 in the below of the alar part 31 ' of Luer lock cone, during the assembling apparatus, side opening 131 is by ring 132 sealings, ring 132 be pressed into for this purpose and arranges in.Compare with prior art (in the prior art, and obtained, the pipe of metal is soldered to the near-end of cutting sleeve pipe to the Luer lock cone as the extension of the pipe of metal), this solution reduces cost greatly.

Two parts 33 of handpiece deviate from along relative direction on diameter from tang 30 mutually with 34.The second portion 34 of handpiece is than first's 33 length and have curved profile to obtain the handpiece of ergonomics.

In the proximal end of tang 30, between two parts 33 and 34 of handpiece, define the support member 5 that can hold plate member and the seat 32 of breech lock 6.Seat 32 is limited between two relative walls 33 ' and 34 ' of handpiece part 33 and 34.Each guiding groove 35 with locking projection 36 is formed in wall 33 ' and 34 '.

In the second portion 34 of handpiece, seat 37 is formed on wall 34 ' back, and the cross section of seat 37 is U-shaped, and is arranged in the part 34 ' of handpiece part 34 and second one 34 " between.

With reference to figure 1,4 and 5, plate member 4 comprises metal tube 40, and the external diameter of metal tube 40 is slightly smaller than the internal diameter Φ 2 of the pipe 20 of sleeve pipe, being guided coaxially in pipe 20 inside of sleeve pipe and slide.The part of the far-end of the pipe 40 of plate member is by axial Cutting Length L2, to obtain semicircular cylinder part 41 substantially.The length L 2 of semicircular cylinder part 41 is about 3-4cm.Far-end in the semicircular cylinder part 41 of plate member is formed with circumferential tooth in

groups

42,43, is arranged in pairs on tooth 42, the 43 diametrically opposed positions.

First pair of tooth 42 is disposed in the far-end of plate member.As illustrating better in Fig. 5, each tooth 42 has trapezoidal a little profile to limit most advanced and sophisticated 45.Second pair of tooth 43 has the leg-of-mutton profile of cardinal principle to limit most advanced and sophisticated 46.Between first pair of tooth 42 and second pair of tooth 43, form the otch 44 of V-arrangement substantially.Be length L 3 from the distance at the tip 46 of far-end to the second tooth 43 of plate member, length L 3 is similar to the length L 1 of the mouth of sleeve pipe.

With reference to figure 6,7 and 8, the support member 5 of the pipe 40 of plate member comprises main body 50, and main body 50 is configured as rectangular slab substantially.Tang 51 be formed on main body 50 in the heart, thereby limiting hole 51 ', hole 51 ' is provided with tapering part 51 ".The near-end of the pipe 40 of plate member is locked in the hole 51, for example drips flared part 51 in tang 51 by suitable glue is set " in.

Two flexible alar parts 52 are arranged along direction relative on diameter with respect to tang 51, and are positioned the edge of two secondary side of main body 50.Groove 52 ' is formed in the outer surface of alar part 52.The surface 52 of the end of each alar part 52 " be suitable taper.By this way, when support member 5 was inserted in the seat 32 of handpiece 3, the flexible alar part 52 of support member slided in the gathering sill 35 of handpiece, thereby curves inwardly, until the groove 52 ' of the alar part of support member 5 by stopper rib 36 snap engagement of handpiece.

Four otch 53 are formed in the main body 50 of support member 5.Each otch 53 limits back butt limit 53a and preceding butt limit 53b.Be arranged in the projection 54 in the centre position, be formed on the longitudinal edge of each otch 53.

With reference to figure 9,10 and 11, breech lock 6 comprises main body 60 general rectangular, curved a little.The main body 60 of breech lock is longer and narrow slightly slightly than the main body 50 of support member 5.Four flexible alar parts 61 are formed in the limit of two main sides of main body 60 of breech lock, two of every sides.Each flexible alar part 61 has tapered end 62, and tapered end 62 limits and keeps surface 63.By this way, the alar part 61 of breech lock can be bonded in the otch 53 of correspondence of support member 5 and breech lock 6 utilizes the maintenance surface 63 of alar part 61 to be maintained on the support member 5, the limit of the otch 53 of alar part 61 butt support members.

The direction of operating of indication breech lock 6 is formed on the main body 60 of breech lock with arrow 64 that can assembling device 1.The stopper rib 65 that limits U-lag 66 is arranged in the side that is pointed to by arrow 64 of main body 60.

When breech lock 6 was in detent position, its alar part 61 was against the back abutment surface 53a of the otch 53 of support member and do not overcome the projection 54 of the centre in the otch 53 of correspondence of support member.In this position, the main body covering that the U-lag of breech lock is 66 supported 5 and the rib-shaped piece 65 of breech lock are concordant with the wall 34 ' (Fig. 3) of the seat 32 of handpiece.Therefore, the support member 5 all-in-one-piece breech locks 6 with plate member can not be pushed in the seat 32 of handpiece.

During along the direction translation of arrow 64, the alar part 61 of breech lock slides in the otch 53 of support member at breech lock, surpasses the center protrusion 54 of otch and against the antetheca 53b of otch 53.As a result, the U-lag 66 of breech lock is outstanding with respect to the main body of support member 5, thereby U-lag self is aimed at and the rib-shaped piece 65 of breech lock is arranged to 37 concordant with handpiece with the wall 34 ' of handpiece.By this way, the assembly that is formed by support member 5 and breech lock 6 can be pushed into the seat 32 of handpiece 3.

With reference to Figure 12 and 13, sealing support member 8 comprises the main body 80 of general rectangular, main body 80 for shaped form a little so that radius of curvature is continuous, two parts 33 of main body 80 connection handpieces and 34.By this way, sealing support member 8 plays lid and covers breech lock 6 well.Porose 82 tang 81 is set is formed in the mid portion of main body 80, the near-end of stylet 7 is fixed in the hole 82.

Operation with particular reference to Figure 14-18 tracing device 1.

As shown in Figure 14 and 15, to install 1 and initially be provided with compact mode, plate member 4 is arranged in the inside of outside sleeve pipe 2 and the inside that stylet 7 is arranged in plate member 4.In this case, the tip 70 of stylet is outstanding from the mouth 21 of sleeve pipe.On the other hand, be arranged in the

tooth

42,43 of the far-end of plate member 4 in the inside of the cylindrical portions may 20 of sleeve pipe, near with the end of mouth 21 link positions that are connected 22 of sleeve pipe.Breech lock 6 is in detent position, thus plate member 4 can not from shown in the position move.

The doctor catches handpiece 3 and utilizes the tip 70 of stylet to carry out the perforation of the tight section of organ, and most advanced and sophisticated 70 are used as the guide portion of the cutting edge 27 of mouth.Near the very moment 21 arrival organ inside, the doctor catches sealing support member 8 and seals support member 8 along the direction pulling of arrow F1, in order to extract stylet 7 out.At this moment, the surgeon is propulsion plant 1 further, so that the cylindrical shape sample of the mouth of sleeve pipe 21 excision organ inside.

As illustrated in fig. 16, after the excision sample, the surgeon moves breech lock 6 along the direction of arrow F2, so that the rib-shaped piece 65 of breech lock and handpiece is 37 concordant, thus latch 6.Then, the doctor can promote breech lock 6 along the axial direction of arrow F3, also promotes support member 5 and plate member 4 simultaneously.The alar part 52 of support member 5 flexibly curves inwardly and the groove 52 ' of alar part discharges from rib-shaped piece 36 buckles of the guide portion 35 of handpiece, thereby allows the operator to promote with plate member 4 all-in-one-piece support members 5 and breech lock 6 to scope as much as possible.The ticktack that the operator can hear is reminded the far-end inlet port of the semicircular cylinder part 41 of his plate member 4, thereby has arrived the terminal point of its stroke, and thereby the

tooth

42 and 43 of reminding his the plate member base portion of sample promptly.

As shown in Figure 17, the semicircular cylinder part 41 of plate member 4 is advanced in the pipeline 25 of sleeve pipe 2, and when

circumferential tooth

42 and 43 runs into the tapered narrowing part 23 that is limited by mouth 21, the

circumferential tooth

42 and 43 that is arranged in the far-end of semicircular cylinder part 41 of plate member radially curves inwardly, as the tine of the base portion of the sample that promptly is cut.As a result,

tooth

42 and 43

tip

45 and 46 form the base portion that hooks the sample that is cut securely.The tapering of the narrowed portion 23 in the sleeve pipe guarantees that

circumferential tooth

42 and 43 radially bends gradually.

Stylet 7 advantageously has the rule that has indentation 71 at its near-end.Compass parts (compass) (not being illustrated in the accompanying drawings) (it will guide stylet 7 to insert the pipe 40 of plate member so if desired) will be provided as adnexa.By this way, before plate member 4 is extracted out, if the operator wishes that so he can be by inserting stylet 7 length that apparatus comes the sample that verification is cut again, these may be by means of above-mentioned guiding compass parts, the compass parts are installed in the proximal location on the breech lock 6, keep having risen how many indentations to read stylet with respect to the compass parts.

At this moment, the operator carries out the rotation of handpiece 3, cuts off the base portion of sample by twisting, and the axial support member 5 of pull plate parts subsequently.By this way, plate member 4 is removed from sleeve pipe 2, and the sample that is cut keeps resting on the semicircular cylinder part 41 of plate member, because the base portion of sample is being kept securely by the

tip

45 and 46 of the tooth 42 of plate member and 43.Should be noted that this operation causes the damage minimum to sample, only in the zone that sample is hooked by the

tip

45 and 46 of tooth.In addition, the loss of sample is actual to be zero, even if in the diverse situation of the fastness of sample.Should be noted that this operation only requires the axial advancement of sleeve pipe 2, and without any swing dislocation motion, to cause in the necessary fracture in the base portion place of sample.

In case plate member 4 is extracted out from sleeve pipe 2, then the sample of sample (core) takes out from the cylindrical portions may 41 of plate member, and this may be by means of the tip 70 of stylet 7.Should be noted that according to the device of the present invention other apparatus of needs not probe for example is to be used for taking out sampled sample.

In addition, utilize according to device of the present invention, can take a sample to very long sample, very the length of Chang sample is substantially equal to the length L 2 of the semicircular cylinder part 41 of plate member, that is, and and greater than the sample of 2cm, preferably approximately 3cm.By this way, the relation between outside and the inside is more favourable for all required lab analysis.

In this operating period of taking out sample, sleeve pipe 2 is retained in the original place, because it can be used to from the inside of organ marrow (blood) be sampled.In fact, as shown in Figure 18, the operator can be with the tip of suction medical treatment device, and for example syringe 9, insert the Luer lock cone 31 of handpiece 3, import sleeve pipe 2 into.Subsequently, by the piston 90 of operating syringe, the blood that is present in organ inside is extracted, and through sleeve pipe 2, enters the chamber 91 of the cylinder of syringe 9.

Should be noted that according to device 1 of the present invention and can after the sampling of sample, carry out sampling to marrow, thereby do not lose the sample (it is important for the analysis that will carry out) of blood cell.

Those skilled in the art's scope in one's power is internal energy carries out various changes and improvement to the current exemplary embodiment of the present invention and do not depart from the scope of the present invention that proposes thus in claims.

Claims

1. the sampler of a human organ (1), it comprises:

Outside sleeve pipe (2), described sleeve pipe are provided with mouthful (21), and described mouth has cutting edge (27) with the sample of cutting spongy bone,

Plate member (4), described plate member be slidably mounted in the described sleeve pipe (2) and the far-end of described plate member be provided with semicircular cylinder part (41) and

Stylet (7), described stylet are slidably mounted in the described plate member (4) and are provided with tip (70), and described tip is outstanding from the described mouth of described sleeve pipe (2), with the outside of puncture organ,

It is characterized in that

Described mouthful (21) of described sleeve pipe portion within it have narrowed portion (23), and the described semicircular cylinder part (41) of described plate member has at least one pair of at the tooth in groups (42 that circumferentially relatively arranges at its far-end, 43), described tooth is suitable for radially curving inwardly when the described narrowed portion (23) that runs into described mouthful, with the base portion of the sample that promptly is cut and allow to take out described sample by means of described plate member (4), described sleeve pipe (2) is maintained at the operating position simultaneously.

2. device according to claim 1 (1) is characterized in that, each tooth (42,43) of described plate member (4) comprises the tip (45,46) that is suitable for penetrating the sample that is cut.

3. device according to claim 1 and 2 (1), it is characterized in that, described plate member (4) comprises the relative tooth (42) and second pair of relative tooth (43) of the first couple that is arranged in its far-end, and the otch (44) that each tooth in wherein said first pair of relative tooth (42) and corresponding tooth in described second pair of relative tooth (43) are formed on the cardinal principle V-arrangement in the semicircular cylinder part (41) of described plate member separates.

4. device according to claim 3 (1) is characterized in that, described first pair of relative tooth (42) has trapezoidal substantially profile and described second pair of relative tooth (43) has leg-of-mutton profile substantially.

5. according to each described device (1) in the aforementioned claim, it is characterized in that the described semicircular cylinder part (41) of described plate member preferably has the length of 3cm.

6. according to each described device (1) in the aforementioned claim, it is characterized in that the described narrowed portion (23) of described mouthful (21) of described sleeve pipe is that the described tooth (42,43) to allow described plate member of taper is crooked gradually.

7. according to each described device (1) in the aforementioned claim, it is characterized in that, described mouthful (21) of described sleeve pipe comprise circle tube member, described circle tube member is soldered to the remote edge of the pipe (20) of described sleeve pipe by laser weld portion (22), described mouthful (21) have the pipe that equals described sleeve pipe external diameter (Φ 1) external diameter (Φ 3) and less than the internal diameter (Φ 4) of the internal diameter (Φ 2) of described sleeve pipe, to described mouthful passage, to limit described narrowed portion (25) at the pipe from described sleeve pipe.

8. according to claim 6 and 7 described devices (1), it is characterized in that the edge of described mouthful (21) that is fixed to the pipe (20) of described sleeve pipe by means of laser weld portion (22) has the flared part (23) of the described narrowed portion that produces taper.

9. according to each described device (1) in the aforementioned claim, it is characterized in that described sleeve pipe (2) utilizes welding to be connected to the pipe of metal, thereby described sleeve pipe and handpiece (3) are become one.

10. according to each described device (1) in the aforementioned claim, it is characterized in that it comprises:

Handpiece (3), described handpiece is fixed to the near-end of described sleeve pipe (2) by the pipe of metal, and the pipe of described metal is connected to described sleeve pipe by welding,

Support member (5), described support member is fixed to the near-end of described plate member (4),

Breech lock (6), described breech lock be slidably mounted on the described support member (5) and

Closing cap (7), described closing cap (7) is fixed to the far-end of described stylet,

Wherein said handpiece (3) has the seat (32) and the described closing cap (7) that are suitable for holding described support member (5) and described breech lock (6) and is suitable for being installed on the described breech lock (6).

11. device according to claim 10 (1) is characterized in that, described breech lock (6) is slidably mounted on the described support member (5), so that:

-from the detent position process, wall (the 34 ') interference of the rib-shaped piece of wherein said breech lock (65) and described handpiece causes that to avoid described breech lock unexpectedly to be promoted described plate member (4) advances prematurely in described sleeve pipe,

-arriving open position, the rib-shaped piece of wherein said breech lock (65) is aimed at the seat (37) of handpiece, is pushed to allow described breech lock, thereby allows described plate member (4) to advance in described sleeve pipe.

12. according to claim 10 or 11 described devices (1), it is characterized in that described handpiece (3) comprising:

Cylindrical shape tang (30), the pipe of metal that wherein is soldered to the near-end of described sleeve pipe (2) be fixed and

The frustum adapter (31) of Luer lock (Luer Lock) type, it is disposed in the described cylindrical shape tang (30) and can approaches to hold the tip of medical science suction apparatus from the described seat (32) of described handpiece, the tip of syringe (9) for example, thus extract blood or marrow from the inside of organ.

13. according to each described device (1) in the claim 10 to 12, it is characterized in that, described handpiece (3) has the human factor engineering shape, and comprise than short first-hand gripping member portion (33) and long second-hand's gripping member portion (34), between first-hand gripping member portion and second-hand's gripping member portion, form described seat (32), to hold the described support member (5) of described plate member, the described closing cap (8) of described breech lock (6) and described stylet, thereby connect first-hand gripping member portion and second-hand's gripping member portion (33,34) seriality of radius of curvature that, keeps the proximal end face of handpiece simultaneously.

14. according to each described device (1) in the claim 10 to 12, it is characterized in that, described stylet (7) has the rule part, and described rule part has scale (71) at the near-end of described stylet, the length of the sample that is cut with verification.