CN103283775B - Synergistic pesticide composition - Google Patents

Synergistic pesticide composition Download PDF

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Publication number
CN103283775B
CN103283775B CN201210044004.0A CN201210044004A CN103283775B CN 103283775 B CN103283775 B CN 103283775B CN 201210044004 A CN201210044004 A CN 201210044004A CN 103283775 B CN103283775 B CN 103283775B
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cyflumetofen
composition
mite
pesticide
profenofos
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CN103283775A (en
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朱卫锋
曹明章
王新军
杨立平
戴兰芳
李广泽
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Shenzhen Novozon Crop Science Co ltd
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Shenzhen Noposion Agrochemicals Co Ltd
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Abstract

The invention relates to a synergistic pesticide composition. The active ingredients of the composition are cyflumetofen and an organophosphorus insecticide, wherein the weight ratio of the cyflumetofen to the organophosphorus insecticide is 20:1-1:50, and the two active ingredients are prepared into various forms including missible oil, microemulsions, EW (emulsions in water), suspending agents, microcapsule suspending agents and suspoemulsions. The composition is used for preventing and controlling pest mites of crops, and especially can be used for preventing and controlling panonychus citri mcgregor and tetranychus urticae koch; and the composition has a synergistic effect, is quick-acting and long-acting, and can reduce consumption of pesticide, save manpower, and contribute to delaying the development of insect resistance.

Description

Synergetic pesticide composition
Technical field
The present invention relates to a kind of composition pesticide, be specifically related to a kind of cyflumetofen and organic phosphorous insecticide composition pesticide of containing, for preventing and treating insect and the evil mite in agricultural.
Background technology
Organic phosphates is the important insecticide of a class, and organophosphorous pesticide still holds pride of place in China's agricultural chemicals usage amount at present.Progressively substitute or partly substitute the some of the pesticide species structural adjustment that high malicious organophosphorous pesticide is China.Harmful mite on agricultural crops is from generation to generation many, and breeding is fast, easily produces resistance, the good miticide kind of some original preventive effects, and as Avermectin, pyridaben etc., through using for a long time for many years, the time that miticidal effect obviously declines or a dispenser is effectively controlled is very short.By the access times of lasting increase agricultural chemicals and the working concentration of raising agricultural chemicals, still cannot reach desirable control efficiency, also increased the murder by poisoning of human and environment has been polluted.
Cyflumetofen: English common name Cyflumetofen; it is the novel acyl group acetonitrile class miticide by the exploitation of Japanese great Zhong chemical company; this medicament is remarkable to mite class effect, if wherein one-tenth mite mite, the ovum of tetranychid are all had to special efficacy, can be used for various melons and fruits, flowers and vegetables.
At present, the cyflumetofen price of selling on market is high, and mostly is unitary agent, and in fact, this unitary agent exists the risk that easily produces resistance in control mite pest.
Summary of the invention
1. goal of the invention
The object of the present invention is to provide a kind of composition pesticide, be characterized in higher to plant insect activity, have obvious synergistic effect, can obviously reduce the usage amount of organophosphorous pesticide, and itself be difficult for producing resistance.
Another object of the present invention is to provide the application of this composition pesticide in agricultural.
2. technical scheme
The agricultural chemicals of different mechanism of action shows three kinds of type of action: summation action, synergistic effect and antagonism after mixing conventionally.But be specially which kind of effect, by lot of experiments, cannot do not determine.Inventor is by large number of biological screening test, is surprised to find that uses that be mixed by a certain percentage of the selected part organophosphorus insecticide of cyflumetofen and the present invention, to doing harm to mite, has synergistic effect, after further study, completed the present invention.
Composition pesticide provided by the present invention, take cyflumetofen and organophosphorus insecticide carries out composite as active ingredient, the organophosphorus insecticides relating to is a kind of in chlopyrifos (chlorpyrifos), Hostathion (triazophos), Profenofos (profenophos), quinalphos (quinalphos) and malathion (malathion), although they there are differences on structure, activity level, evil mite is had to the essentially identical mechanism of action and similar effect feature.
In composition pesticide of the present invention, active ingredient cyflumetofen and organic phosphorous insecticide mass ratio are 20 :-1: 50, and preferred proportion is 1: 1-1: 20.
Composition pesticide of the present invention is mixed with any one formulation that those skilled in the art are familiar with in actual applications, and preferred formulation is missible oil, microemulsion, aqueous emulsion, micro-capsule suspension, suspension emulsion.Active ingredient total content in preparation is 5%~60%.
Auxiliary material in present composition preparation comprises that emulsifier, solvent, stabilizing agent, antifreezing agent, dispersant, carrier and other are of value to the known substance of active ingredient stable and drug effect performance in preparation, be all composition conventional in pesticidal preparations field, be not particularly limited.
Composition pesticide of the present invention, for preventing and treating the insect that occurs on crops or evil mite, especially can effectively prevent and treat the Tetranychus urticae of the crops such as Panonychus citri, apple of the crops such as citrus.
3. beneficial effect
Cyflumetofen and the organic phosphorous insecticide composition pesticide of containing provided by the invention, can produce following beneficial effect:
(1) this composition pesticide has synergistic function to evil mite, can improve control efficiency, reduces agricultural chemicals usage amount, thereby has reduced the harmful effect of environment and residue of pesticide.
(2) this composition pesticide has expanded control spectrum, and a dispenser is pest control and evil mite simultaneously.
(3) mechanism of action of two kinds of active ingredients of this composition pesticide is different, has notable synergistic effect, and the use that is mixed can delay evil mite pesticide resistance and produce and development.
Embodiment
Below in conjunction with embodiment, the invention will be further described, not for limiting the present invention.
In embodiment, in the proportioning of all preparations, percentage is mass percent.The treatment dosage of biologicall test part and the test of pesticide effectiveness is effective ingredient consumption.
Embodiment 1: cyflumetofen, Profenofos and the toxicity test of different proportioning to citrus red mite (crm)
Test method is with reference to the agricultural industry criteria NY/T1154.12-2006 > > of the < < People's Republic of China (PRC).Pick up from the female one-tenth mite of citrus red mite (crm) in field, through indoor feeding three generations, select the female one-tenth mite of growth uniformity as supplying examination worm.Adopt seedling method, on little basin citrus seedling, connect 50~60 mites of Panonychus citri, after 1 day, check radix, choose except after dead mite, mend to add and live into mite, retaining every processing mite number is 50 left and right.Will have the seedling of mite use spray tower to spray, moves under 25 ℃, relative moisture 90% condition and cultivates, microscopy after 15 hours, the record number of surviving, carries out statistical analysis with DPS data processing software, obtains LC 50, mode of application adopts abundant co-toxicity coefficient (CTC) method that waits nineteen sixty proposition of Sun Yun.The computing formula of co-toxicity coefficient is as follows:
Actual measurement toxicity index (ATI)=(standard medicament LC 50/ reagent agent LC 50) * 100
The percentage composition of B in percentage composition+B medicament ATI * mixture of A in theoretical toxicity index (TTI)=A medicament ATI * mixture
Co-toxicity coefficient (CTC)=(mixture ATI/ mixture TTI) * 100
When CTC≤80, composition performance is for antagonism, and as 80 < CTC < 120, composition performance is for summation action, and when CTC >=120, composition performance is synergistic effect.
Result of the test is in Table 1.
The toxicity test of table 1 cyflumetofen, Profenofos and different proportioning citrus red mite (crm)s (15 days)
From table 1, when the weight ratio of cyflumetofen and Profenofos was mixed between 20: 1~1: 50, each proportioning co-toxicity coefficient has all reached more than 120, shows certain synergistic effect; When the part by weight of cyflumetofen and Profenofos was mixed between 1: 1~1: 20, CTC is higher than 200, and synergy is more remarkable.Composition shows as obvious synergistic effect to the virulence of citrus red mite (crm).
Embodiment 2: cyflumetofen, quinalphos and the toxicity test of different proportioning to Tetranychus urticae
Test method reference and the agricultural industry criteria NY/T1154.12-2006 > > of the < < People's Republic of China (PRC).Pick up from the female one-tenth mite of Tetranychus urticae in field, through indoor feeding three generations, select the female one-tenth mite of growth uniformity as supplying examination worm.Adopt cotton seedling method, test method and statistical method are with embodiment 1.
Result of the test is in Table 2.
The toxicity test of table 2 cyflumetofen, quinalphos and different proportioning Tetranychus urticaes (15 days)
From table 2, when the weight ratio of cyflumetofen and quinalphos was mixed between 20: 1~1: 50, each proportioning co-toxicity coefficient has all reached more than 120, shows certain synergistic effect; When the part by weight of cyflumetofen and quinalphos was mixed between 1: 1~1: 20, composition shows as obvious synergistic effect to the virulence of Tetranychus urticae.
Embodiment 3: cyflumetofen, Hostathion and the toxicity test of different proportioning to Tetranychus cinnabarinus
Test method is with reference to the agricultural industry criteria NY/T1154.12-2006 > > of the < < People's Republic of China (PRC).Pick up from the female one-tenth mite of Tetranychus cinnabarinus in field, through indoor feeding three generations, select the female one-tenth mite of growth uniformity as supplying examination worm.Adopt tomato seedling method, test method and statistical method are with embodiment 1.
Result of the test is in Table 3.
The toxicity test of table 3 cyflumetofen, Hostathion and different proportioning Tetranychus cinnabarinus (15 days)
From table 3, when the weight ratio of cyflumetofen and Hostathion was mixed between 20: 1~1: 50, each proportioning co-toxicity coefficient has all reached more than 120, shows certain synergistic effect.
Embodiment 4:20% cyflumetofen. the compound method of chlorpyrifos aqueous emulsion
By formula requirement, by above component by the amount of formula according to the processing that feeds intake of conventional aqueous emulsion processing method, even finally by shear agitation, make 20% cyflumetofen. chlorpyrifos aqueous emulsion.
Embodiment 5:31% cyflumetofen. the compound method of quinalphos suspending agent and medicament field trial
By formula requirement, above component is mixed by the amount of formula, after grinding, sand mill obtains 31% cyflumetofen. quinalphos suspending agent.
This embodiment preparation is used for preventing and treating granulated sugar tangerine garden tangerine mandarin orange Panonychus citri.The control of employing spray-on process.During dispenser, field Panonychus citri becomes mite more.5 processing are established in test altogether, and each is processed 4 times and repeats.Before dispenser, investigate field insect population radix, within after medicine 1,7 and 21 day, respectively investigate 1 time insect pest situation, calculate control efficiency, and use DPS to carry out difference analysis.
Control efficiency is as shown in table 4.
Table 4 cyflumetofen, quinalphos and mixture thereof the control efficiency to citrus red mite (crm)
Note: have same letter person to show that difference is not remarkable after same column of figure
As shown in Table 4, after cyflumetofen and quinalphos are composite, complex preparation is used separately compared with single dose, and the control efficiency of citrus red mite (crm) is improved a lot, and agricultural chemicals dosage reduces, and can effectively reduce the harmful effect of environment and residue of pesticide.
Embodiment 6:51% cyflumetofen. the compound method of profenofos emulsion in water and medicament field trial
By formula requirement, the mix and blends such as cyflumetofen, Profenofos, cosolvent, emulsifier are dissolved and make oil phase, under constantly stirring, antifreezing agent, water, thickener are fully stirred into water, water is directly added in oil phase, stir about 30min, obtains emulsion liquid, after sample analysis is qualified, obtains 51% cyflumetofen. profenofos emulsion in water.
This embodiment preparation is used for preventing and treating apple orchard Tetranychus urticae.The control of employing spray-on process.During dispenser, field two variegated leafs become mite more.Test each and process 4 repetitions.Before dispenser, investigate field insect population radix, within after medicine 1,7 and 21 day, respectively investigate 1 time insect pest situation, calculate control efficiency, and carry out difference analysis with DPS.
Control efficiency is as shown in table 5.
Table 5 cyflumetofen, Profenofos and mixture thereof the control efficiency to Tetranychus urticae
Note: have same letter person to show that difference is not remarkable after same column of figure
As shown in Table 5, after cyflumetofen and Profenofos are composite, complex preparation is used separately compared with single dose, and the control efficiency of Tetranychus urticae is improved a lot, and agricultural chemicals dosage reduces, and can effectively reduce the harmful effect of environment and residue of pesticide.
Embodiment 7:21% cyflumetofen. the compound method of Karbofos emulsion in water
By above component by the amount of formula according to the processing that feeds intake of conventional aqueous emulsion processing method, even finally by shear agitation, make 21% cyflumetofen. Karbofos emulsion in water.
Embodiment 8:30% cyflumetofen. the formula of malathion micro-capsule suspension
Embodiment 9:20% cyflumetofen. the compound method of triazophos emulsifiable solution
By formula requirement, former medicine, solvent, dispersant etc. are added together, and through stirring, make 20% cyflumetofen. triazophos emulsifiable solution.
Embodiment 10:21% cyflumetofen. the formula of Profenofos suspension emulsion
Embodiment 11:21% cyflumetofen. the compound method of Profenofos missible oil
By formula requirement, former medicine, solvent, emulsifier are added together, and stir and make 21% cyflumetofen. Profenofos missible oil.
Embodiment 12:20% cyflumetofen. the compound method of Profenofos missible oil
By formula requirement, take the various compositions such as cyflumetofen, Profenofos, former medicine, solvent, emulsifier are added together, and stir and make 20% cyflumetofen. Profenofos missible oil.
Embodiment 13:21% cyflumetofen. the compound method of triazophos micro-emulsion
By formula requirement, take the various compositions such as cyflumetofen, Hostathion, first with dimethyl formamide, dissolve, ratio in formula adds propane diols, calcium dodecyl benzene sulfonate to mix, under agitation mixture is added to the water, makes 21% cyflumetofen after being stirred to evenly. triazophos micro-emulsion.
This embodiment preparation is used for preventing and treating Tetranychus urticae on cotton.The control of employing spray-on process.During dispenser, two variegated leafs become mite more.Cotton leaf bug on the cotton of same plot and cotten aphid occur also more.Test each and process 4 repetitions.Before dispenser, investigation field insect population radix, respectively investigates 1 time insect pest situation for after medicine 1,7 and 21 day, calculates control efficiency, uses DPS to carry out difference analysis.
Control efficiency is as shown in table 6.
Table 6 cyflumetofen, Hostathion and mixture thereof the control efficiency to Tetranychus urticae
Note: have same letter person to show that difference is not remarkable after same column of figure
As shown in Table 6, after cyflumetofen and Triazoxide as built-up, complex preparation is used separately compared with single dose, and the control efficiency of Tetranychus urticae is improved a lot, and agricultural chemicals dosage reduces, and can effectively reduce the harmful effect of environment and residue of pesticide.
Duration of test is also observed built agent also has very good effect to the cotton leaf bug on cotton, aphid, and within 7 days, drug effect reaches 95.82% and 96.56%, and 20% cyflumetofen suspending agent single dose to cotton leaf bug and aphid substantially to no effect.Show that built agent compares single dose and expanded control spectrum.

Claims (3)

1. a composition pesticide, is characterized in that active ingredient is comprised of cyflumetofen and Profenofos, and wherein the mass ratio of cyflumetofen and Profenofos is 20: 1~1: 50.
2. composition pesticide according to claim 1, the mass ratio of effective ingredient cyflumetofen and Profenofos is 1: 1~1: 20.
3. composition pesticide according to claim 1 and 2, is characterized in that being mixed with missible oil, microemulsion, aqueous emulsion, suspending agent, micro-capsule suspension or suspension emulsion.
CN201210044004.0A 2012-02-23 2012-02-23 Synergistic pesticide composition Active CN103283775B (en)

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Publication number Priority date Publication date Assignee Title
CN103493842B (en) * 2013-10-11 2015-07-15 江苏龙灯化学有限公司 Insecticidal composition
CN103493841A (en) * 2013-10-11 2014-01-08 江苏龙灯化学有限公司 Insecticidal composition
CN104115861B (en) * 2014-06-12 2016-10-05 广东中迅农科股份有限公司 A kind of insecticide acaricide composition containing sulfur-phosphor and cyflumetofen

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Publication number Priority date Publication date Assignee Title
CN1446196A (en) * 2000-08-11 2003-10-01 大塚化学控股株式会社 Acylacetonitriles, process for preparation thereof and miticides containing the same
WO2008009379A2 (en) * 2006-07-18 2008-01-24 Bayer Cropscience Ag Active ingredient combinations having insecticide and acaricide properties
CN102164491A (en) * 2008-08-18 2011-08-24 先正达参股股份有限公司 Insecticidal combinations comprising abamectin and cyflumetofen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1446196A (en) * 2000-08-11 2003-10-01 大塚化学控股株式会社 Acylacetonitriles, process for preparation thereof and miticides containing the same
WO2008009379A2 (en) * 2006-07-18 2008-01-24 Bayer Cropscience Ag Active ingredient combinations having insecticide and acaricide properties
CN102164491A (en) * 2008-08-18 2011-08-24 先正达参股股份有限公司 Insecticidal combinations comprising abamectin and cyflumetofen

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Address after: 518102 No. 113 Reservoir Road, Baoan District, Guangdong, Shenzhen, Xixiang

Patentee after: Shenzhen Novozon Crop Science Co.,Ltd.

Country or region after: China

Address before: 518102 No. 113 Reservoir Road, Baoan District, Guangdong, Shenzhen, Xixiang

Patentee before: SHENZHEN NOPOSION AGROCHEMICALS Co.,Ltd.

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