CN103239702A

CN103239702A - Medicament for treating dysmenorrhea

Info

Publication number: CN103239702A
Application number: CN2013101972773A
Authority: CN
Inventors: 温美珍
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-05-24
Filing date: 2013-05-24
Publication date: 2013-08-14

Abstract

The invention relates to a medicament for treating dysmenorrhea. The medicament is prepared from traditional Chinese medicines as bulk pharmaceuticals. A tablet product of the medicament is prepared by using the steps of uniformly mixing rhizoma cyperi, three-nerved spicebush root, szechwan Chinaberry fruit, rhizoma corydalis, fennel, folium artemisiae argyi, fructus evodiae, baked ginger, pseudo-ginseng, ligusticum wallichii, myrrh, pollen typhae, trogopterus dung, herba lycopi, morinda officinalis, fructus psoraleae, astragalus mongholicus, Chinese angelica, elecampane and Chinese thorowax root, crushing the mixture into 100-200 meshes of powder and tableting the powder according to a conventional method. The medicament is used for treating by taking the purposes of prompting qi circulation to relive pain, warming channels, invigorating blood circulation, nourishing liver and kidney, benefiting qi and nourishing blood as principles and has a good treatment on dysmenorrhea and no side effect.

Description

A kind of medicine for the treatment of dysmenorrhea

Technical field

The present invention relates to a kind of medicine for the treatment of dysmenorrhea, especially relating to a kind of is the medicine of the treatment dysmenorrhea of crude drug preparation with Chinese medicine.

Background technology

Dysmenorrhea is also referred to as pain in menstrual period, is clinical common disease, is mainly in the youth.Pain was common and betided most of menstrual cycle periodic menstrual period, dysmenorrhea often be angor and with the lower back portion pain, feel sick, vomiting, headache or suffer from diarrhoea.Dysmenorrhea is divided into primary dysmenorrhea and secondary dysmenorrhea two classes, and primary dysmenorrhea refers to that the genitals does not have the dysmenorrhea of organic disease, accounts for more than 90% of dysmenorrhea; Secondary dysmenorrhea refers to the dysmenorrhea that the pelvic cavity organic disease causes, endometriosis, adenomyosis are the common causes of secondary dysmenorrhea.Many women can have the situation of slight discomfort in menstrual period, but this can not think simply that dysmenorrhea, dysmenorrhea refer to that the pain in menstrual period has influenced normal activity, and needs Drug therapy, dysmenorrhea can have a strong impact on women's operate as normal life, severe patient even may cause infertility.

Summary of the invention

The purpose of this invention is to provide a kind of is the medicine of the treatment dysmenorrhea of crude drug preparation with Chinese medicine, and this medicine is with promoting the circulation of QI to relieve pain, and warming the meridian and activating blood circulation, nourishing the liver and kidney, benefiting qi and nourishing blood are the principle treatment, and be effective to TREATMENT OF DYSMENORRHOEA, has no side effect.

Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:

Rhizoma Cyperi 8～12 Radixs Linderae 8～12 Fructus Toosendans 8～12 Rhizoma Corydalis 8～12

Fructus Foeniculi 6～10 Folium Artemisiae Argyis 8～12 Fructus Evodiaes 6～10 Rhizoma Zingiberis Preparatums 6～10

Radix Notoginseng 8～12 Rhizoma Chuanxiongs 8～12 Myrrhas 4～8 Pollen Typhaes 6～10

Oletum Trogopterori 6～10 Herba Lycopi 6～10 Radix Morindae Officinaliss 8～12 Fructus Psoraleaes 8～12

The Radix Astragali 8～12 Radix Angelicae Sinensis 8～12 Radix Aucklandiae 6～10 Radix Bupleuri 6～10.

Preferably, medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:

Rhizoma Cyperi 10 Radixs Linderae 10 Fructus Toosendans 10 Rhizoma Corydalis 10

Fructus Foeniculi 8 Folium Artemisiae Argyis 10 Fructus Evodiaes 8 Rhizoma Zingiberis Preparatums 8

Radix Notoginseng 10 Rhizoma Chuanxiongs 10 Myrrhas 6 Pollen Typhaes 8

Oletum Trogopterori 8 Herba Lycopi 8 Radix Morindae Officinaliss 10 Fructus Psoraleaes 10

The Radix Astragali 10 Radix Angelicae Sinensis 10 Radix Aucklandiae 8 Radix Bupleuri 8.

The medicine of above-mentioned each component can be made said peroral dosage form on any pharmaceuticss such as powder, capsule, pill, and the preferred dosage form of the present invention is tablet.

The concrete preparation method of medicinal tablet of the present invention is: said medicine by described parts by weight mix homogeneously, is ground into 100～120 purpose medicated powder, and tabletting makes the tablet product according to a conventional method.

The traditional Chinese medical science thinks dysmenorrhea mainly owing to qi depression to blood stasis, obstructed, the deficient qi and blood of stagnating, dash and appoint deficient causing.Dysmenorrhea patient's feelings will is unsuccessful, the irritability depression, and duration dash to be appointed, and uterus stagnation of QI blood is contained, mechanism of qi retardance and cause qi depression to blood stasis and cause dysmenorrhea; Cold having the property of coagulation easily blocks yang-energy, brave the rain menstrual period, paddle, occupy for a long time wetland, cold-damp is hindered in the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, surfeit is cold and cool, cold originating from the interior or innate deficiency of YANG in the body, yin-cold excess, the cold-evil is objective appoints in dashing, meet again through preceding menstrual period dash to appoint, the uterus QI and blood stops up and contains, the cold-evil fights mutually with QI and blood and causes sluggish obstructed initiation dysmenorrhea; The kidney being the origin of congenital constitution, spleen kidney deficiency or intemperate sexual intercourse, voluminous exhaustion due to sexual indulgence, liver-blood deficiency, through after essence and blood benefit empty, dash that to appoint a uterus to lose in moistening foster, deficient qi and blood, dash and appoint deficient and cause dysmenorrhea; In a word, dysmenorrhea with qi depression to blood stasis, cold coagulation uterus, deficient qi and blood, dash appoint deficient be main diseases because of.The Therapeutic Principle should be promoting the circulation of QI to relieve pain, warming the meridian and activating blood circulation, nourishing the liver and kidney, benefiting qi and nourishing blood.Rhizoma Cyperi, the Radix Linderae, Fructus Toosendan, Rhizoma Corydalis, the Radix Aucklandiae, Radix Bupleuri play the circulation of qi promoting effect of having a respite jointly in the prescription of the present invention, and a uterus dash to be appointed in the dysmenorrhoea disease position, and fortuneization is in QI and blood, and the capable then blood of gas is capable, and gas transfers then pain certainly only along blood; Fructus Foeniculi, Folium Artemisiae Argyi, Fructus Evodiae, Rhizoma Zingiberis Preparatum be the product of warming YANG all, and yang-energy general rule gas is logical, dash and appoint the uterus QI-blood circulation freely then not bitterly; Blood stasis can cause pain, and it is the main cause of dysmenorrhea that blood stasis is stagnated, the present invention with Radix Notoginseng, Rhizoma Chuanxiong, Myrrha, Pollen Typhae, Oletum Trogopterori, the common blood circulation promoting and blood stasis dispelling of Herba Lycopi blood is transferred and pain only." element is asked _.Ancient times, innocence was discussed " say " menarche, conception vessel is logical, the favourable opposition full and forceful pulse, menses is with under the thing ", wantonly two arteries and veins are dashed in normally depending on of menstruation.Noted liver and kidney tonifying among the present invention, benefiting vital QI and blood, Radix Morindae Officinalis in the side, Fructus Psoraleae, the Radix Astragali, Radix Angelicae Sinensis and the liver and the kidney tonifying.In a word, our various medicines are played altogether, promoting the circulation of QI to relieve pain, and warming the meridian and activating blood circulation, nourishing the liver and kidney, benefiting qi and nourishing blood and play analgesic effect altogether can play the purpose of taking stopgap measures and effecting a permanent cure to TREATMENT OF DYSMENORRHOEA.

For further investigating the clinical efficacy of Drug therapy dysmenorrhea of the present invention, select 64 routine dysmenorrhea patients to carry out clinical observation on the therapeutic effect.

64 routine patients are all according to the diagnosis basis in " disease of tcm diagnosis criterion of therapeutical effect ":

1, menstrual period or before and after row lower abdomen pain, pain and waist sacrum are very then fainted.Be periodical attack;

2, good sending out in young maiden;

3, suffer from abdominal pain due to the eliminating pelvic cavity organic disease;

Be diagnosed as dysmenorrhea.

Therapeutic Method

Adopt tablet medicine of the present invention, 3 times on the one, each 10, every 0.5g.

Criterion of therapeutical effect

Criterion of therapeutical effect with reference to " disease of tcm diagnosis criterion of therapeutical effect ".Cure: pain disappears, and recurrence is seen at continuous 3 menstrual cycle ends; Take a turn for the better: pain relief or pain disappear, but can not keep more than 3 months; Do not heal: pain is not seen improvement.

All case treatment back efficacy result sees Table 1.

Table 1 is case treatment back efficacy result all.

The example number	Cure n(%)	Improvement n(%)	N(% more)	Total effective rate n(%)
					64	40（62.5）	21（32.8）	3（4.7）	61（95.3）

Concrete case

Case one

Zhang, woman, 17 years old, suffered from dysmenorrhea 4 years, body constitution is thin and weak usually, and 13 years are through menophania, menstruation irregularis, 4-7/20-50 days, the 2-3 day pain of menstruation very accompanied pale complexion, extreme cold of the limbs, pain alleviated while getting warmth, treatments such as oral YUANHU ZHITONG PIAN, ibuprofen, Aifu Nuangong Wan are once imitated not good enough, and learning pressure increases the weight of greatly.Use tablet medicine of the present invention, every day three times, each 10, the treatment back takes a turn for the better.

Case two

The king so-and-so, 23 years old, 14 years were through rising, dysmenorrhea always after the menophania was married in 22 years old, 1 son is arranged after marriage, plain body still can, menstruation 4-5/22-25 days, amount is few, color is dim, dysmenorrhea continues whole menstrual period, and preceding 2 days pains very need be taken the somedon pain relieving at every turn, once takes western medicines in treatment and imitates not good enough.Use tablet medicine treatment of the present invention back to cure.

The specific embodiment

Embodiment 1

Get Rhizoma Cyperi 8g, the Radix Linderae 8 g, Fructus Toosendan 8 g, Rhizoma Corydalis 8 g, Fructus Foeniculi 6 g, Folium Artemisiae Argyi 8 g, Fructus Evodiae 6 g, Rhizoma Zingiberis Preparatum 6 g, Radix Notoginseng 8 g, Rhizoma Chuanxiong 8 g, Myrrha 4 g, Pollen Typhae 6 g, Oletum Trogopterori 6 g, Herba Lycopi 6 g, Radix Morindae Officinalis 8 g, Fructus Psoraleae 8 g, the Radix Astragali 8 g, Radix Angelicae Sinensis 8 g, the Radix Aucklandiae 6 g, Radix Bupleuri 6 g mix homogeneously, be ground into 100～120 purpose medicated powder, tabletting makes the tablet product according to a conventional method.

Embodiment 2

Get Rhizoma Cyperi 12g, the Radix Linderae 12 g, Fructus Toosendan 12 g, Rhizoma Corydalis 12 g, Fructus Foeniculi 10 g, Folium Artemisiae Argyi 12 g, Fructus Evodiae 10 g, Rhizoma Zingiberis Preparatum 10 g, Radix Notoginseng 12 g, Rhizoma Chuanxiong 12 g, Myrrha 8 g, Pollen Typhae 10 g, Oletum Trogopterori 10 g, Herba Lycopi 10 g, Radix Morindae Officinalis 12 g, Fructus Psoraleae 12 g, the Radix Astragali 12 g, Radix Angelicae Sinensis 12 g, the Radix Aucklandiae 10 g, Radix Bupleuri 10 g mix homogeneously, be ground into 100～120 purpose medicated powder, tabletting makes the tablet product according to a conventional method.

Embodiment 3

Get Rhizoma Cyperi 10 g, the Radix Linderae 10 g, Fructus Toosendan 10 g, Rhizoma Corydalis 10 g, Fructus Foeniculi 8 g, Folium Artemisiae Argyi 10 g, Fructus Evodiae 8 g, Rhizoma Zingiberis Preparatum 8 g, Radix Notoginseng 10 g, Rhizoma Chuanxiong 10 g, Myrrha 6 g, Pollen Typhae 8 g, Oletum Trogopterori 8 g, Herba Lycopi 8 g, Radix Morindae Officinalis 10 g, Fructus Psoraleae 10 g, the Radix Astragali 10 g, Radix Angelicae Sinensis 10 g, the Radix Aucklandiae 8 g, Radix Bupleuri 8 g mix homogeneously, be ground into 100～120 purpose medicated powder, tabletting makes the tablet product according to a conventional method.

Claims

1. medicine for the treatment of dysmenorrhea is that crude drug prepares by the Chinese medicine of following portions by weight:

2. the medicine for the treatment of dysmenorrhea according to claim 1 is that crude drug prepares by the Chinese medicine of following portions by weight:

Rhizoma Cyperi 10 Radixs Linderae 10 Fructus Toosendans 10 Rhizoma Corydalis 10

Radix Notoginseng 10 Rhizoma Chuanxiongs 10 Myrrhas 6 Pollen Typhaes 8

3. the medicine for the treatment of dysmenorrhea according to claim 1 is characterized in that described medicine is made tablet.