CN103202728A - Single microwave treatment needle with multiple acting sites - Google Patents
Single microwave treatment needle with multiple acting sites Download PDFInfo
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- CN103202728A CN103202728A CN2013100179002A CN201310017900A CN103202728A CN 103202728 A CN103202728 A CN 103202728A CN 2013100179002 A CN2013100179002 A CN 2013100179002A CN 201310017900 A CN201310017900 A CN 201310017900A CN 103202728 A CN103202728 A CN 103202728A
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Abstract
The invention discloses an implantable tumor conformal ablation single microwave needle with multiple acting sites. The microwave needle comprises an ablation emitting front electrode, insulating media, an ablation needle body and a handle, the insulating media are positioned between the emitting front electrode and the ablation needle body, the front end of the ablation needle body is connected with the ablation emitting front electrode, the tail end of the ablation needle body extends into the handle, a microwave coaxial cable inside the ablation needle body penetrates through the whole needle body, penetrates through the insulating media to be connected with the emitting front electrode and penetrates through the handle to be connected with a microwave high-frequency joint below the handle, and at least two insulating media are arranged at different positions of the ablation needle body. By arranging two or a plurality of microwave ablation acting sites at different positions on the single microwave treatment needle, a similarly ellipsoidal area with a narrow upper portion and a wide lower portion formed on a single insulating medium site is changed, a fine similarly spherical or columnar destruction area is formed at a position far away from the insulating medium sites, a tumor is conformally ablated, puncture frequency is decreased, and treatment risk is reduced.
Description
Technical field
The present invention relates to a kind of one-time treatment apparatus, relate in particular to the single needle multiaction site micro-wave therapeutic pin that a kind of tumor conformal shape of implanted is melted.
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Background technology
Microwave ablation is a kind of localized heat ablation techniques, has characteristics such as thermal efficiency height, temperature rise is fast, the high temperature thermal field is even, solidification zone is downright bad thoroughly, the hyperemia band is narrower, is used widely for many years.Clinical carrying out microwave ablation when treatment, the doctor is inserted into predetermined tumor specific part with the puncture of micro-wave therapeutic pin and carries out ablation according to the image data of ultrasonic or CT.According to the difference of factors such as tumor size, shape, microwave frequency is generally 2.45GHz, 915MHz, power from 20W to 80W about, treatment time was not generally waited to 10 minutes at several minutes.Now be applied to clinical micro-wave therapeutic pin for single-acting site treatment pin, namely before emission, have only a dielectric opening between the utmost point and the body.Be subjected to the restriction of this structure, when it acts on biological tissue, biological tissue to the specific absorption rate (SAR) of microwave energy along the needle body direction with perpendicular to needle body direction skewness, therefore the shape that melts that produces generally is approximately elliposoidal, major diameter and minor axis differ bigger, and major diameter is generally 1.5-2 times of minor axis.In clinical treatment for spherical tumor or other non-spheroid shapes, tumor in irregular shape, for with its thorough damage, just may cause damage to normal surrounding tissue, therefore can't take disposable suitable shape ablation, melt thereby can only repeatedly puncture to melt or be used in combination spininess, this just may increase the side effect for the treatment of or jeopardize normal organ on every side, has strengthened the risk for the treatment of.
Summary of the invention
Technical problem to be solved by this invention is, improves existing single micro-wave therapeutic at the damage effect of tumor, can enough fit the shape ablation to different tumors.A kind of single needle multiple spot micro-wave therapeutic pin provided by the invention, by two or more microwave ablation action sites of diverse location are set at single micro-wave therapeutic pin, change a single dielectric and put formed up-narrow and down-wide similar elliposoidal zone, make in the position away from the dielectric site, form spheroidal or column damage district preferably, realize the suitable shape of tumor is melted, reduce and pierce through number of times, reduce the treatment risk, improve and melt efficient.
For solving the problems of the technologies described above, the present invention can realize by following technical proposal: a kind of single needle multiaction site micro-wave therapeutic pin, comprise melt the emission before the utmost point 1, dielectric opening 2, melt needle body 3, handle 6; Dielectric opening 2 utmost point 1 and melting between the needle body 3 before emission, described melt needle body 3 front ends connect melt the utmost point 1 before the emission, end extends to handle 6 inside, handle 6 afterbodys are provided with fixed mount and are used for the outside socket that is connected, and its outside socket that connects comprises the microwave high-frequency joint; Melt needle body 3 inside and comprise microwave coaxial cable, described microwave coaxial cable runs through whole needle body, passing dielectric links to each other with the utmost point 1 before the emission, microwave coaxial cable passes handle 6, below handle 6, connect the microwave high-frequency joint, it is characterized in that: at the diverse location that melts on the needle body, the dielectric that comprises more than at least 2 is set.
In above-mentioned micro-wave therapeutic pin, described dielectric length is 1-10mm.
According to first kind above-mentioned or second kind of single needle multiaction site micro-wave therapeutic pin, it is characterized in that: be provided with cooling water cavity in the described handle, the described needle body 3 that melts is connected with the water cavity of handle inside; Described socket for the outside connection has comprised cooling water inlet pipe 7, outlet pipe 8; The described needle body 3 that melts, inside contain and microwave coaxial cable capillary water cooling tube side by side, and described capillary water cooling tube end extends in the interior water cavity of handle, and are connected with water inlet pipe; Described outlet pipe 8 communicates with the water cavity afterbody; The described microwave coaxial cable that passes handle 6, its end extend in the interior water cavity of handle, and the top of described microwave high-frequency joint is in water cavity.
Described handle 6 inside arrange temperature sensor.
The described needle body 3 surface markers puncture graduation mark 4 that melts.
Described melting is arranged with positioning sleeve 5 on the needle body 3.
Described capillary water cooling tube is that stainless steel material is made, and quantity is one or more.
Described needle body 3 surfaces of melting have anti-stick coating.
Described dielectric is exposed to the needle body surface, and the material that uses is the tetrafluoroethene material.
Compared with prior art, this patent has following advantage:
1, changes in the prior art a single dielectric and put formed up-narrow and down-wide similar elliposoidal zone, make in the position away from the dielectric site, form the damage district of spheroidal preferably or column, realization is melted the suitable shape of tumor, reduce and pierce through number of times, reduce the treatment risk, improve and melt efficient.
The single needle multiple spot micro-wave therapeutic pin that the present invention relates to arranges the dielectric that comprises more than at least 2 on its needle body.Therefore parameter differences such as the dielectric openings of sizes of different treatment pins, distance can produce difform ablation areas, thereby have the feature ablation effect.In the clinical treatment, damage effect in order to reach best tumor, the doctor can select to have different characteristic ablation effect micro-wave therapeutic pin, to reach the purpose of conformal therapy tumor according to the difference of factors such as the size of tumor, shape, position.
2, dielectric length is 1-10mm.Widened the length range of dielectric greatly.
Description of drawings
Fig. 1 is the single needle multiple spot micro-wave therapeutic pin sketch map of this patent invention.
Fig. 2 is the single needle multiple spot micro-wave therapeutic pin needle body front end internal structure sketch map of this patent invention.
Fig. 3 is single needle multiple spot micro-wave therapeutic pin needle body and the handle internal structure sketch map of this patent invention.
Fig. 4 is the hepatic tissue microwave ablation simulation result of existing single needle single-point micro-wave therapeutic pin.
Fig. 5 is the hepatic tissue microwave ablation simulation result of 2 micro-wave therapeutic pins of the novel single needle of this patent.
Fig. 6 is the hepatic tissue microwave ablation simulation result of novel 2 the micro-wave therapeutic pins of another kind of single needle of this patent.
Fig. 7 is the hepatic tissue microwave ablation simulation result of novel 2 the micro-wave therapeutic pins of the third single needle of this patent.
Fig. 8 is the hepatic tissue microwave ablation simulation result of 4 micro-wave therapeutic pins of the novel single needle of this patent.
Fig. 9 carries out the scheme sketch map of tumor conformal shape ablation for adopting the novel single needle multiple spot micro-wave therapeutic pin of this patent.
Among Fig. 1-Fig. 3:
1, the utmost point before the emission, 2, dielectric, 3, melt needle body, 4, Biao Mian graduation mark, 5, positioning sleeve, 6, handle, 7, water inlet pipe, 8, outlet pipe, 9.1, microwave coaxial cable, 9.2, the microwave high-frequency joint, 10.1 capillary water cooling tube, 10.2, water cavity, 10.3, bend pipe, 11, temperature sensor.
Fig. 4 ~ Fig. 7: for emulation single needle multiple spot micro-wave therapeutic pin in the COM SOL Multiphysics of multiple physical field simulation software melts the result of Hepar Sus domestica.What show in the axial symmetry mode among the figure is to melt the temperature field isothermal line that finishes the back hepatic tissue, the result shows by the diverse location of adjusting the dielectric action site and size can influence the shape in microwave ablation zone, thereby forms the feature ablation effect of different single needle multiple spot micro-wave therapeutic pins.
Fig. 4 is the simulation result that melts for existing single needle single-point micro-wave therapeutic pin, and distributing to melt as can be seen from its temperature field is shaped as up-narrow and down-wide similar elliposoidal zone.This micro-wave therapeutic pin can make biological tissue produce higher energy specific absorption rate perpendicular to the direction of needle body, but shrinks rapidly in the position ablation areas away from the dielectric site, can not form the district of spherical damage preferably.
Fig. 5 is improved single needle two point micro-wave therapeutic pin, has two dielectric openings at needle body, selects optimum dielectric openings of sizes and distance under the specific dimensions of this pin, can access desirable ablation areas.Simulation result shows that more multipotency is absorbed by the tissue perpendicular to the needle body direction, and the temperature field that is similar to spheroid distributes and the damage district thereby formed.
Fig. 6 and Fig. 7 are another kind of single needle two point micro-wave therapeutic pins, and its dielectric extended distance is bigger, and purpose is in order to make tissue obtain more energy to absorb, form specific two spherical ablation areas that link to each other being parallel to the needle body direction.Fig. 6 makes the spheroid of needle body back segment generation bigger than the size that Fig. 5 has strengthened needle body leading portion dielectric opening.
Fig. 8 is 4 micro-wave therapeutic pins of a kind of single needle, and four dielectric action sites that distribute at needle body make energy evenly distribute along the needle body parallel direction is approximate, and the temperature field becomes cylinder within the specific limits, obtains another feature ablation effect.
Above simulation result shows, compared with prior art, geometric parameters such as the size of the present invention by control dielectric action site, distance, can carry out controllable adjustment to damaging the zone, clinically can be according to the shape of tumor and position different, use the single needle of optimum ablation effect or use the spininess combination with minimum puncture cost, form spherical or column damage district preferably, realization is melted the suitable shape of tumor, reduces the treatment risk, improves and melts efficient.
The specific embodiment
Below in conjunction with accompanying drawing the specific embodiment of the present invention is elaborated:
As shown in Figure 1 to Figure 3, water-cooled single needle multiple spot micro-wave therapeutic pin comprises: launch the preceding utmost point 1, melt needle body 3 and a plurality of dielectric action site 2.1,2.2,2.3 that melts, melt microwave coaxial cable 9.1, the capillary water cooling tube 10.1 of needle body 3 inside, melt graduation mark 4, the positioning sleeve 5 on needle body 3 surfaces, handle 6, the water cavity 10.2 of handle 6 inside, temperature sensor 11, the microwave high-frequency joint 9.2 of handle 6 belows, water inlet pipe 7 and outlet pipe 8, bend pipe 10.3.Its microwave frequency of using can be 2.45GHz and 915MHz.Positioning sleeve 5 is used for demarcating and limiting the paracentesis depth of micro-wave therapeutic pin.The needle body surface has anti-stick coating, and is marked with graduation mark 4 and comes indicating length.
Dielectric opening utmost point 1 and melting between the needle body 3 before emission, dielectric 2.1,2.2,2.3 length are 1-10mm, the material of dielectric can be the tetrafluoroethene material.Dielectric is exposed to the needle body surface, and a plurality of action sites that are combined into microwave ablation of two or more dielectric openings form the feature ablation effect for the treatment of pin.
Microwave coaxial cable is used for the transmission microwave energy, and it runs through and melts needle body, and front end passes dielectric 2.1,2.2,2.3, adopts crimping or welding procedure to connect to melt the utmost point before the emission.The part of microwave coaxial cable in needle body is by cooling off with its capillary water cooling tube side by side.Microwave coaxial cable passes handle 6, below handle 6, connect the microwave high-frequency joint, handle 6 is convenient to the staff and is gripped in use, handle 6 afterbodys are provided with fixing and are used for the outside socket that is connected, comprise microwave high-frequency joint, cooling water inlet pipe 7, outlet pipe 8, be provided with cooling water cavity in the handle, needle body 3 and handle 6 are melted in the cooling that can circulate.
The recirculated water of cooling usefulness is entered into through handle by water inlet pipe and melts needle body, and the capillary water cooling tube is melting needle body inside, extends to behind a nearest dielectric of handle to return in the handle, connects the water cavity front end, and the handle of flowing through is flowed out by outlet pipe again.The capillary water cooling tube is generally stainless steel material and makes, and can be many.The water inlet joint is positioned at water cavity bottom chamber body wall, join with water inlet pipe 7,10.1 terminal linking to each other of the upper end of water inlet joint in water cavity 10.2 and capillary water cooling tube, the front end of capillary water cooling tube 10.1 extends water cavity 10.2 and enters and melt in the needle body 6, with microwave coaxial cable side by side.The outlet joint is in water cavity 10.2 bottom chamber body walls, and outlet pipe 8 joins, and upper end and bend pipe 10.3 one ends of outlet joint in water cavity 10.2 join, and bend pipe 10.3 ends extend to water cavity 10.2 afterbodys.When work, cooling water flows into by melting the junction of needle tubing 6 with water cavity 10.2 heads in the water cavity 10.2, by bend pipe 10.3 terminal outflows, thereby make the cooling water in the water cavity 7 be full of water cavity 10.2 all the time and be in recurrent state, microwave coaxial cable and high-frequency joint in the water cavity 10.2 cool off among recirculated water all the time.
Temperature sensor is located on the water cavity wall, and temperature sensor can be critesistor, and the temperature of recirculated cooling water when being used for surveying work, its certainty of measurement can reach ± and 0.2 ℃.
Claims (9)
1. single needle multiaction site micro-wave therapeutic pin comprises and melts the utmost point, dielectric before the emission, melts needle body, hands handle; Dielectric utmost point and melting between the needle body before emission, described melt the needle body front end connect melt the utmost point before the emission, end extends to handle inside, the handle afterbody is provided with the socket that connects for the outside, its outside socket that connects comprises the microwave high-frequency joint; Melt needle body inside and comprise microwave coaxial cable, described microwave coaxial cable runs through whole needle body, extremely link to each other before passing dielectric and launching, microwave coaxial cable passes handle, below handle, connect the microwave high-frequency joint, it is characterized in that: at the diverse location that melts on the needle body, the dielectric that comprises more than at least 2 is set.
2. according to the described a kind of single needle multiaction of claim 1 site micro-wave therapeutic pin, it is characterized in that: described dielectric length is 1-10mm.
3. according to claim 1 or 2 described a kind of single needle multiaction site micro-wave therapeutic pins, it is characterized in that: be provided with cooling water cavity in the described handle, the described needle body end that melts is connected with the water cavity of handle inside; Described socket for the outside connection has comprised cooling water inlet pipe, outlet pipe; The described needle body that melts, inside is contained and microwave coaxial cable capillary water cooling tube side by side, and described capillary water cooling tube one end extends in the interior water cavity of handle, and is connected with water inlet pipe, the other end of capillary cooling tube is communicated with the water cavity leading portion, and the water cavity afterbody communicates with described outlet pipe; The described microwave coaxial cable that passes handle, its end extend in the interior water cavity of handle.
4. according to the described a kind of single needle multiaction of claim 3 site micro-wave therapeutic pin, it is characterized in that: handle inside arranges temperature sensor.
5. according to the described a kind of single needle multiaction of claim 4 site micro-wave therapeutic pin, it is characterized in that: described ablation needle surface labelling puncture graduation mark.
6. according to the described a kind of single needle multiaction of claim 5 site micro-wave therapeutic pin, it is characterized in that: described melting is arranged with positioning sleeve on the needle body.
7. according to the described a kind of single needle multiaction of claim 6 site micro-wave therapeutic pin, it is characterized in that: described capillary water cooling tube is that stainless steel material is made, and quantity is one or more.
8. according to the described a kind of single needle multiaction of claim 7 site micro-wave therapeutic pin, it is characterized in that: the described needle body surface of melting has anti-stick coating.
9. according to the described a kind of single needle multiaction of claim 8 site micro-wave therapeutic pin, it is characterized in that: described dielectric is exposed to the needle body surface, and the material that uses is the tetrafluoroethene material.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2013100179002A CN103202728A (en) | 2013-01-17 | 2013-01-17 | Single microwave treatment needle with multiple acting sites |
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| CN2013100179002A CN103202728A (en) | 2013-01-17 | 2013-01-17 | Single microwave treatment needle with multiple acting sites |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104546126A (en) * | 2015-01-21 | 2015-04-29 | 范卫君 | Microwave ablation antenna for interventional treatment of lung cancer |
| CN105520782A (en) * | 2016-02-02 | 2016-04-27 | 四川大学华西医院 | Water-cooled electromagnetic bleeding-stopping needle |
| CN106109009A (en) * | 2016-06-13 | 2016-11-16 | 南京航空航天大学 | A kind of water-cooled microwave ablation needle using 433MHz frequency |
| CN106236255A (en) * | 2016-08-25 | 2016-12-21 | 庞茂英 | There is blood vessel microwave melt needle and the preparation method of temperature controlling function |
| CN106420047A (en) * | 2016-08-25 | 2017-02-22 | 庞茂英 | Microwave-type tumor ablating needle with temperature control function |
| WO2017133024A1 (en) * | 2016-02-02 | 2017-08-10 | 四川大学华西医院 | Multi-opening electromagnetic hemostat needle mounted on cannula |
| CN107049476A (en) * | 2017-04-20 | 2017-08-18 | 北京工业大学 | A kind of voltage source characterizing method that feedback is surveyed based on single needle |
| CN107865691A (en) * | 2017-11-22 | 2018-04-03 | 安徽硕金医疗设备有限公司 | A kind of water-cooled microwave ablation needle of magnetic resonance compatible |
| CN108392264A (en) * | 2018-02-11 | 2018-08-14 | 安徽大中润科技有限公司 | Microwave ablation needle and manufacturing method thereof |
| CN109247984A (en) * | 2018-09-29 | 2019-01-22 | 南京亿高微波系统工程有限公司 | A kind of microwave melt needle with water cold sleeve applied under Bronchofiberscope |
| CN113116514A (en) * | 2021-05-07 | 2021-07-16 | 南京诺源医疗器械有限公司 | Microwave ablation analysis system |
| CN113143445A (en) * | 2021-03-11 | 2021-07-23 | 上海交通大学 | Radiofrequency ablation probe system capable of conformal thermal ablation |
| CN113729920A (en) * | 2021-09-28 | 2021-12-03 | 深圳迈微医疗科技有限公司 | Bimodal tissue ablation needle |
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| US20060149226A1 (en) * | 2005-01-06 | 2006-07-06 | Scimed Life Systems, Inc. | Co-access bipolar ablation probe |
| CN2815296Y (en) * | 2005-05-27 | 2006-09-13 | 陈鹏宏 | Silica gel treating catheter for microwave thermotherapy apparatus |
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Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104546126A (en) * | 2015-01-21 | 2015-04-29 | 范卫君 | Microwave ablation antenna for interventional treatment of lung cancer |
| WO2017133024A1 (en) * | 2016-02-02 | 2017-08-10 | 四川大学华西医院 | Multi-opening electromagnetic hemostat needle mounted on cannula |
| CN105520782A (en) * | 2016-02-02 | 2016-04-27 | 四川大学华西医院 | Water-cooled electromagnetic bleeding-stopping needle |
| CN106109009A (en) * | 2016-06-13 | 2016-11-16 | 南京航空航天大学 | A kind of water-cooled microwave ablation needle using 433MHz frequency |
| CN106109009B (en) * | 2016-06-13 | 2018-06-26 | 南京航空航天大学 | A kind of water-cooled microwave ablation needle using 433MHz frequencies |
| CN106420047A (en) * | 2016-08-25 | 2017-02-22 | 庞茂英 | Microwave-type tumor ablating needle with temperature control function |
| CN106236255A (en) * | 2016-08-25 | 2016-12-21 | 庞茂英 | There is blood vessel microwave melt needle and the preparation method of temperature controlling function |
| CN107049476A (en) * | 2017-04-20 | 2017-08-18 | 北京工业大学 | A kind of voltage source characterizing method that feedback is surveyed based on single needle |
| CN107049476B (en) * | 2017-04-20 | 2019-07-26 | 北京工业大学 | A kind of voltage source characterizing method based on single needle actual measurement feedback |
| CN107865691A (en) * | 2017-11-22 | 2018-04-03 | 安徽硕金医疗设备有限公司 | A kind of water-cooled microwave ablation needle of magnetic resonance compatible |
| CN108392264A (en) * | 2018-02-11 | 2018-08-14 | 安徽大中润科技有限公司 | Microwave ablation needle and manufacturing method thereof |
| CN109247984A (en) * | 2018-09-29 | 2019-01-22 | 南京亿高微波系统工程有限公司 | A kind of microwave melt needle with water cold sleeve applied under Bronchofiberscope |
| CN109247984B (en) * | 2018-09-29 | 2024-01-12 | 南京亿高医疗科技股份有限公司 | Microwave ablation needle with water-cooling sleeve applied under bronchofiberscope |
| CN113143445A (en) * | 2021-03-11 | 2021-07-23 | 上海交通大学 | Radiofrequency ablation probe system capable of conformal thermal ablation |
| CN113116514A (en) * | 2021-05-07 | 2021-07-16 | 南京诺源医疗器械有限公司 | Microwave ablation analysis system |
| CN113729920A (en) * | 2021-09-28 | 2021-12-03 | 深圳迈微医疗科技有限公司 | Bimodal tissue ablation needle |
| WO2023051165A1 (en) * | 2021-09-28 | 2023-04-06 | 深圳迈微医疗科技有限公司 | Dual-mode tissue ablation needle |
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Application publication date: 20130717 |