CN103191295A - Medicine for treating diabetes mellitus - Google Patents
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Abstract
The invention discloses a medicine for treating diabetes mellitus, relating to the field of traditional Chinese medicines. The medicine is prepared from the following traditional Chinese medicine raw materials in parts by weight: 160-200 parts of kudzuvine root, 160-200 parts of radix astragali, 160-200 parts of dwarf lilyturf tuber, 160-200 parts of radix rehmanniae, 160-200 parts of snakegourd root, 40-60 parts of liquorice, 40-60 parts of Chinese magnoliavine fruit and 50-70 parts of bitter gourd. Through dialectical compatibility, the medicines jointly achieve the functions of nourishing yin and engendering liquid, clearing away heat and moistening dryness, nourishing the liver and kidney and quenching thirst and mainly treat upset, thirst, malaise, blurred vision and diabetes mellitus. The prepared medicine has short course of treatment and avoids relapse.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of medicine for the treatment of diabetes.
Background technology
Diabetes are a series of clinical syndromes absolute because of insulin in the body or that relative deficiency causes, and are related with gene close.Its main clinical manifestation is polydipsia, polyuria, polyphagia and weight loss, and contains glucose etc. in the blood glucose height, urine.
World Health Organization (WHO) is divided into four types with diabetes: type 1 diabetes generally is because the β cell of autoimmune system destruction generation insulin causes; Type 2 diabetes mellitus is owing to histiocytic insulin resistant, the decline of β cell function or other multiple reasons cause; Gestational diabetes comes from the insulin resistant of cell, and its insulin resistant is because the hormone of pregnancy women secretion causes; The other types diabetes.Dissimilar diabetes all can cause the β cell in the pancreas can not produce the insulin of capacity with the concentration of blood sugar lowering, cause the generation of hyperglycemia.
At present, 1, type 2 diabetes mellitus still can not cure fully, mainly be to cooperate hypoglycemic medicine or insulin to replenish the treatment diabetes that combine by diet control.Main medicine has: biguanides, the output by reducing hepatic glucose and improve peripheral insulin resistance and blood sugar lowering; Sulfonylurea drugs by stimulating the beta Cell of islet excreting insulin, increases the interior insulin level of body and blood sugar lowering; The thiazolidinediones medicine, the blood sugar lowering by increasing target cell to the sensitivity of insulin action; The meglitinide medicine reduces post-prandial glycemia by the early stage secretion that stimulates insulin; Alpha-glucosidase inhibitor reduces post-prandial glycemia by suppressing carbohydrate in the absorption of upper part of small intestine.CN102266525A discloses a kind of medicine for the treatment of diabetes, but its selected raw material of Chinese medicine kind is more.
Summary of the invention
The present invention proposes a kind of medicine for the treatment of diabetes, but this medicine YIN nourishing and the production of body fluid promoting, clearing heat and moistening dryness, nourishing the liver and kidney, quench the thirst.
The technical solution used in the present invention is as follows:
A kind of medicine for the treatment of diabetes, it is to be made by following Chinese medicinal raw materials in portion by weight: 160～200 parts of Radix Puerariaes, 160～200 parts of the Radixs Astragali, 160～200 parts of Radix Ophiopogonis, 160～200 parts in the Radix Rehmanniae, 160～200 parts of Radix Trichosanthis, 40～60 parts in Radix Glycyrrhizae, 40～60 parts of Fructus Schisandrae Chinensis, 50～70 parts in Fructus Momordicae charantiae.
Preferably, the weight portion proportioning of each raw material of Chinese medicine is: 170～190 parts of Radix Puerariaes, 170～190 parts of the Radixs Astragali, 170～190 parts of Radix Ophiopogonis, 170～190 parts in the Radix Rehmanniae, 170～190 parts of Radix Trichosanthis, 50～60 parts in Radix Glycyrrhizae, 50～60 parts of Fructus Schisandrae Chinensis, 60～70 parts in Fructus Momordicae charantiae.
Preferably, the weight portion proportioning of each raw material of Chinese medicine is: 180 parts of Radix Puerariaes, 180 parts of the Radixs Astragali, 180 parts of Radix Ophiopogonis, 180 parts in the Radix Rehmanniae, 180 parts of Radix Trichosanthis, 50 parts in Radix Glycyrrhizae, 50 parts of Fructus Schisandrae Chinensis, 60 parts in Fructus Momordicae charantiae.
Above-mentioned a kind of medicine for the treatment of diabetes, specifically adopt following step to make:
It is raw material that a takes by weighing Radix Puerariae, the Radix Astragali, Radix Ophiopogonis, the Radix Rehmanniae, Radix Trichosanthis, Radix Glycyrrhizae, Fructus Schisandrae Chinensis and Fructus Momordicae charantiae respectively according to above-mentioned weight proportion, above-mentioned raw materials is ground into fine powder, sieves the coarse grain in the fine powder is separated, then with 100 purpose fine powder mix homogeneously, molding;
After b above-mentioned steps a finishes, add water in the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball, temperature is 65 ℃ of oven dry, pack warehouse-in.
Pharmacology of the present invention and useful technique effect:
Powder of Radix Puerariae sweet in the mouth suffering cool in nature, multiple function such as having induces sweat brings down a fever, promote the production of body fluid, rash, yang invigorating antidiarrheal, can control fever caused by exogenous pathogens headache, hypertension neck pain, thirsty, quench one's thirst, measles without adequate eruption, heat rash, multiple disease such as have loose bowels; Radix Astragali sweet in the mouth, slightly warm in nature is returned liver, spleen, lung, kidney channel, has benefiting QI for strengthening the superficies, arresting sweating to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema admittedly; Sweet, the little hardship of property Radix Ophiopogonis, cold, Yin-nourishing and body fluid promoting, nourishing the lung to arrest cough, the relieving restlessness that clears away heart-fire cure mainly symptoms such as consumption of body fluid caused by febrile disease, vexed, thirsty, dry pharynx lung-heat, cough, pulmonary tuberculosis; The Radix Rehmanniae also is Radix Rehmanniae, the effect that has clearing away heat and cooling blood, tonifying YIN to promote the production of body fluid, and Li Shizhen (1518-1593 A.D.) was once estimated Radix Rehmanniae " one hundred days of clothes are rosy cheeks, make light of one's life by commiting suicide not old in 3 years "; Radix Trichosanthis has clearing away heat-fire, promoting the production of body fluid to quench thirst, the effect of evacuation of pus detumescence, cure mainly control calentura thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid flaccidity, diabetes etc.; Radix Glycyrrhizae has pharyngalgia, removes pathogenic heat, delays healthy energy, yin nourishing blood, tonifying the spleen and stomach, the effect of lung moistening; Fructus Schisandrae Chinensis have astringe the lung, nourishing kidney, the effect of promoting the production of body fluid; Fructus Momordicae charantiae has clearing summer heat, the detoxifcation that makes eye bright, reducing pressure and sugar, diuresis removing heat from blood, separate that labor clears away heart-fire, the effect of QI invigorating tonifying YANG, have cool, thirst-quenching, heat-clearing and toxic substances removing, clear away heart-fire make eye bright, QI invigorating recovers from fatigue, the kidney tonifying diuretic actions.In a word, above-mentioned eight flavor medicines are through dialectical compatibility, and effect such as play YIN nourishing and the production of body fluid promoting, clearing heat and moistening dryness, nourishing the liver and kidney altogether, quench the thirst cures mainly restlessness and thirst, malaise, blurred vision etc. and diabetes, drug prepared of the present invention, and short treating period does not recur.
Clinical data
1, case is selected: select 60 examples to suffer from the outpatient service prescription on individual diagnosis person of diabetes at random, male 22 examples, women 38 examples, 24 years old of age minimum, oldest 62 years old;
2, clinical primary symptom: restlessness and thirst, malaise, blurred vision etc. and diabetes
3, Therapeutic Method: oral, one time one bag (specification 6g/ bag), twice on the one;
4, points for attention: quit smoking, wine and pungent, raw and cold, greasy food; Deficiency and coldness of spleen and stomach, the careful usefulness of stool lingering diarrhea person; The anemia of pregnant woman should take under the doctor instructs;
5, untoward reaction: idol has nauseating, gastral cavity abdomen discomfort, vomiting, diarrhoea;
6, curative effect judging standard: (with take one month be one the course for the treatment of standard)
Cure: symptom all disappears, and blood glucose target is all normal, and spirit is healthy and vigorous;
Produce effects: symptom disappears substantially, and the state of an illness is clearly better, and blood glucose target obviously descends, thirsty improvement to some extent;
Effectively: sx, the state of an illness is controlled, and blood glucose target does not raise;
Invalid: symptom is no change before and after treatment.
Annotate: the normal index of blood glucose is empty stomach 3.9～6.1mmol/L, and 2 hours after the meal is 3.9～7.8mmol/L;
The blood glucose of diabetics is on an empty stomach greater than 7.8mmol/L, and 2 hours after the meal greater than 11.1mmol/L.
7, therapeutic effect
As shown in table 1, adopted Drug therapy of the present invention one month, cure 48 examples, produce effects 9 examples, effective 3 examples, invalid 0 example, the patient of inadaptation does not appear in total effective rate 100%.
Table 1
| The patient | The example number | Healing/example | Produce effects/example | Effectively/example | Invalid/example | Total effectively example |
| The women | 38 | 30 | 6 | 2 | 0 | 38 |
| The male | 22 | 18 | 3 | 1 | 0 | 22 |
| Amount to | 60 | 48 | 9 | 3 | 0 | 60 |
8, model case
Model case one:
Mrs Cao, 24 years old, went to a doctor in February, 2012;
The main suit: extremely thirsty, anorexia, lose weight, faint;
Check: blood glucose is 11.5mmol/L on an empty stomach, is 14.2mmol/L in 2 hours after the meal, and is thirsty, loses weight, and is diagnosed as diabetics;
Treatment: oral, a 6g, 2 times on the one.The patient chemically examines blood glucose after one month, its blood glucose is 6.0mmol/L on an empty stomach, and 2 hours after the meal is 7.6mmol/L, and complexion is clearly better, and thirsty symptom also disappears;
Efficacy determination: cure.
Model case two:
Mr. Zhu, 48 years old, on March 1st, 2012 went to a doctor;
The main suit: urine often, and the urine amount is also many, even the foam of urine is many, the urine stain is turned white, is clamminess, extremely thirsty, heart beating is quick, breathes slowly and dark, takes Western medicine more than 2 years;
Check: blood glucose is 14.6mmol/L on an empty stomach, is 16.2mmol/L in 2 hours after the meal, and is thirsty, loses weight, and is diagnosed as diabetics;
Treatment: oral, a 6g, 2 times on the one.The patient chemically examines blood glucose after one month, its blood glucose obviously reduces, and continues to take this medicine two weeks, chemical examination blood glucose: be 6.0mmol/L on an empty stomach, 2 hours after the meal is 7.7mmol/L, and complexion is gradually good, and thirsty symptom also disappears substantially;
Efficacy determination: produce effects.
Model case three:
Mr. Cao, 62 years old, on March 6th, 2012 went to a doctor;
The main suit: frequent micturition and urine amount are many, and extremely thirsty, heart beating is quick, takes Western medicine more than 5 years;
Check: blood glucose is 14.8mmol/L on an empty stomach, is 17.1mmol/L in 2 hours after the meal, and is thirsty, is diagnosed as diabetics;
Treatment: oral, a 6g, 2 times on the one.The patient chemically examines blood glucose after one month, its blood glucose does not raise, and continues to take this medicine one month, chemical examination blood glucose: be 5.8mmol/L on an empty stomach, 2 hours after the meal is 7.6mmol/L, and spirit is healthy and vigorous, and thirsty symptom all disappears;
Efficacy determination: effectively.
The specific embodiment
Embodiment 1:
Get 160 parts of Radix Puerariaes, 160 parts of the Radixs Astragali, 170 parts of Radix Ophiopogonis, 160 parts in the Radix Rehmanniae, 180 parts of Radix Trichosanthis, 40 parts in Radix Glycyrrhizae, 50 parts of Fructus Schisandrae Chinensis, 50 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 2:
Get 180 parts of Radix Puerariaes, 160 parts of the Radixs Astragali, 170 parts of Radix Ophiopogonis, 180 parts in the Radix Rehmanniae, 180 parts of Radix Trichosanthis, 50 parts in Radix Glycyrrhizae, 50 parts of Fructus Schisandrae Chinensis, 50 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 3:
Get 170 parts of Radix Puerariaes, 160 parts of the Radixs Astragali, 160 parts of Radix Ophiopogonis, 180 parts in the Radix Rehmanniae, 180 parts of Radix Trichosanthis, 50 parts in Radix Glycyrrhizae, 50 parts of Fructus Schisandrae Chinensis, 50 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 4:
Get 190 parts of Radix Puerariaes, 170 parts of the Radixs Astragali, 180 parts of Radix Ophiopogonis, 170 parts in the Radix Rehmanniae, 180 parts of Radix Trichosanthis, 50 parts in Radix Glycyrrhizae, 50 parts of Fructus Schisandrae Chinensis, 60 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 5:
Get 200 parts of Radix Puerariaes, 180 parts of the Radixs Astragali, 200 parts of Radix Ophiopogonis, 190 parts in the Radix Rehmanniae, 190 parts of Radix Trichosanthis, 60 parts in Radix Glycyrrhizae, 50 parts of Fructus Schisandrae Chinensis, 60 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 6:
Get 200 parts of Radix Puerariaes, 190 parts of the Radixs Astragali, 180 parts of Radix Ophiopogonis, 180 parts in the Radix Rehmanniae, 190 parts of Radix Trichosanthis, 50 parts in Radix Glycyrrhizae, 50 parts of Fructus Schisandrae Chinensis, 70 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 7:
Get 180 parts of Radix Puerariaes, 180 parts of the Radixs Astragali, 180 parts of Radix Ophiopogonis, 180 parts in the Radix Rehmanniae, 180 parts of Radix Trichosanthis, 50 parts in Radix Glycyrrhizae, 50 parts of Fructus Schisandrae Chinensis, 60 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 8:
Get 180 parts of Radix Puerariaes, 200 parts of the Radixs Astragali, 190 parts of Radix Ophiopogonis, 200 parts in the Radix Rehmanniae, 180 parts of Radix Trichosanthis, 50 parts in Radix Glycyrrhizae, 60 parts of Fructus Schisandrae Chinensis, 70 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 9:
Get 160 parts of Radix Puerariaes, 160 parts of the Radixs Astragali, 190 parts of Radix Ophiopogonis, 200 parts in the Radix Rehmanniae, 180 parts of Radix Trichosanthis, 55 parts in Radix Glycyrrhizae, 45 parts of Fructus Schisandrae Chinensis, 60 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 10:
Get 200 parts of Radix Puerariaes, 170 parts of the Radixs Astragali, 195 parts of Radix Ophiopogonis, 185 parts in the Radix Rehmanniae, 180 parts of Radix Trichosanthis, 50 parts in Radix Glycyrrhizae, 60 parts of Fructus Schisandrae Chinensis, 60 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 11:
Get 180 parts of Radix Puerariaes, 180 parts of the Radixs Astragali, 190 parts of Radix Ophiopogonis, 180 parts in the Radix Rehmanniae, 200 parts of Radix Trichosanthis, 55 parts in Radix Glycyrrhizae, 55 parts of Fructus Schisandrae Chinensis, 65 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Embodiment 12:
Get 185 parts of Radix Puerariaes, 170 parts of the Radixs Astragali, 190 parts of Radix Ophiopogonis, 200 parts in the Radix Rehmanniae, 200 parts of Radix Trichosanthis, 55 parts in Radix Glycyrrhizae, 60 parts of Fructus Schisandrae Chinensis, 50 parts in Fructus Momordicae charantiae, above-mentioned eight flavor medicated powder are broken into fine powder, sieve the coarse grain in the fine powder is separated, to add water in 100 purpose fine powder mix homogeneously, molding, the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball then, temperature be 65 ℃ of oven dry, pack warehouse-in.
Claims (4)
1. a medicine for the treatment of diabetes is characterized in that it is to be made by following Chinese medicinal raw materials in portion by weight: 160～200 parts of Radix Puerariaes, 160～200 parts of the Radixs Astragali, 160～200 parts of Radix Ophiopogonis, 160～200 parts in the Radix Rehmanniae, 160～200 parts of Radix Trichosanthis, 40～60 parts in Radix Glycyrrhizae, 40～60 parts of Fructus Schisandrae Chinensis, 50～70 parts in Fructus Momordicae charantiae.
2. a kind of medicine for the treatment of diabetes according to claim 1, it is characterized in that: the weight portion proportioning of each raw material of Chinese medicine is: 170～190 parts of Radix Puerariaes, 170～190 parts of the Radixs Astragali, 170～190 parts of Radix Ophiopogonis, 170～190 parts in the Radix Rehmanniae, 170～190 parts of Radix Trichosanthis, 50～60 parts in Radix Glycyrrhizae, 50～60 parts of Fructus Schisandrae Chinensis, 60～70 parts in Fructus Momordicae charantiae.
3. a kind of medicine for the treatment of diabetes according to claim 1, it is characterized in that: the weight portion proportioning of each raw material of Chinese medicine is: 180 parts of Radix Puerariaes, 180 parts of the Radixs Astragali, 180 parts of Radix Ophiopogonis, 180 parts in the Radix Rehmanniae, 180 parts of Radix Trichosanthis, 50 parts in Radix Glycyrrhizae, 50 parts of Fructus Schisandrae Chinensis, 60 parts in Fructus Momordicae charantiae.
4. according to claim 1 or 2 or 3 described a kind of medicines for the treatment of diabetes, it is characterized in that: described medicine specifically adopts following step to make:
It is raw material that a takes by weighing Radix Puerariae, the Radix Astragali, Radix Ophiopogonis, the Radix Rehmanniae, Radix Trichosanthis, Radix Glycyrrhizae, Fructus Schisandrae Chinensis and Fructus Momordicae charantiae respectively according to above-mentioned weight proportion, above-mentioned raw materials is ground into fine powder, sieves the coarse grain in the fine powder is separated, then with 100 purpose fine powder mix homogeneously, molding;
After b above-mentioned steps a finishes, add water in the fine powder after the molding, the general ball of Succus Momordicae charantiae, select ball, temperature is 65 ℃ of oven dry, pack warehouse-in.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013101347912A CN103191295A (en) | 2013-04-18 | 2013-04-18 | Medicine for treating diabetes mellitus |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2013101347912A CN103191295A (en) | 2013-04-18 | 2013-04-18 | Medicine for treating diabetes mellitus |
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| CN103191295A true CN103191295A (en) | 2013-07-10 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104721683A (en) * | 2015-04-01 | 2015-06-24 | 青岛大学附属医院 | Traditional Chinese medicinal patch for treating gestational diabetes mellitus and preparation method thereof |
| CN108686095A (en) * | 2018-07-23 | 2018-10-23 | 张云洲 | A kind of Traditional Chinese medicine for decreasing blood sugar |
| CN110354202A (en) * | 2019-07-30 | 2019-10-22 | 吉林农业科技学院 | The preparation process of glutinous rehmannia Xiaoke Tablets |
| CN113041316A (en) * | 2021-03-20 | 2021-06-29 | 洛阳蓝凯生物科技有限公司 | Natural herbal tea capable of reducing blood sugar and preparation method thereof |
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| CN108686095A (en) * | 2018-07-23 | 2018-10-23 | 张云洲 | A kind of Traditional Chinese medicine for decreasing blood sugar |
| CN110354202A (en) * | 2019-07-30 | 2019-10-22 | 吉林农业科技学院 | The preparation process of glutinous rehmannia Xiaoke Tablets |
| CN113041316A (en) * | 2021-03-20 | 2021-06-29 | 洛阳蓝凯生物科技有限公司 | Natural herbal tea capable of reducing blood sugar and preparation method thereof |
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