CN103191275A - Pharmaceutical composition for treating serious thrush of equus animals - Google Patents
Pharmaceutical composition for treating serious thrush of equus animals Download PDFInfo
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- CN103191275A CN103191275A CN2013101400647A CN201310140064A CN103191275A CN 103191275 A CN103191275 A CN 103191275A CN 2013101400647 A CN2013101400647 A CN 2013101400647A CN 201310140064 A CN201310140064 A CN 201310140064A CN 103191275 A CN103191275 A CN 103191275A
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Abstract
The invention discloses a pharmaceutical composition for treating serious thrush of equus animals; the pharmaceutical composition comprises the components in parts by weight: 23-27 parts of salicylic acid powder, 4-6 parts of iodoform, 13-17 parts of alums, 23-27 parts of potassium permanganate powder, 8-12 parts of sulfanilamide powder and 18-22 parts of resina draconis powder; a using method of the pharmaceutical composition comprises the steps of: cleaning and soaking the hoof parts of the equus animals, and removing rotten cutin, surface excrescences and necrotic tissues; burning affected parts by hot vegetable oil; grinding the pharmaceutical composition into fine powder and then mixing the fine powder; dipping the medicine powder by a cotton ball and filling the medicine powder into the rotten parts, and covering sterilized gauze onto the rotten parts with the medicine powder; spreading pine tar outside the sterilized gauze, and padding gauze rolls; and binding bandage on the whole hoofs, and then spreading the pine tar. The pharmaceutical composition is organically combined, is dialectical in compatibility of medicines and enables the medicines to supplement with one another, and the effects of removing the rotten parts and regenerating new tissues as well as diminishing inflammation and stopping bleeding can be improved, so that the aim of curing the serious thrush can be achieved. The pharmaceutical composition is easy in material obtaining and convenient to prepare, reduces the drug residue and toxic and side effects, and is low in price and high in treatment effect.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of equus severe thrush, belong to the animal field of medicaments.
Background technology
The thrush of equus is that Horse hoof frog cutin is corrupt when decomposing with the chronic suppurative inflammation of frog corium.Be the normal a kind of disease sent out of mule.Initial stage many from the frog lateral sulcus or ditch begin, can spread to full frog gradually.Back hoof is multiple, and four hoof take place simultaneously sometimes.
The various factors that all influences or destruction hoof open and close function is the reason that causes primary disease.As cut when striding attached fork and cut lowly, frog angle and frog prop up connecting portion and thoroughly do not cut out, and the heel wall cuts deficiency or interior outside heel wall cuts different high; Relatively rear is followed closely in shoeing at present, surplus edge and surplus tail deficiency; Adorning toe calk, thick tail shoes or the rubber palm for a long time; Heel is narrow, the hoof that inclines, plant distortion such as hoof hoof; Long-term drylot feeding, hypomotility all can influence or destroy the switching function of hoof.In addition, mismanagement, is that the stud-farm is unclean at mew, and fecaluria, mud gather, at the bottom of not noting digging hoof, wash hoof and removing hoof, damage etc. takes place frog dirt or frog portion, often becomes the immediate cause of thrush.
The trouble frog initial stage of rotting only limits to the frog cutin and rots to decompose, and loses its normal shape or rots into cavity and the crack that varies in size, the development of the course of disease thereupon, the liquid of discharge grey black stench.When pathological changes was not encroached on corium, general nothing was walked lamely.When pathological changes has been damaged corium, then cause slight pain.The limping characteristics are in hag motion limping weightening finish, to walk lamely then slight in the hard place motion.During serious symptom, suffer from hoof and often recommend, the fortune step is medium degree walks lamely, and heel portion bears a heavy burden uncertain, or only lands with the hoof point.Heel portion temperature raises, and refers to that (toe) tremulous pulse is slightly hyperfunction, and it is painful sick that pincers press frog portion to have, and the frog cutin is all cracked or come off sometimes, and corium exposes.Through thrush more of a specified duration, when inflammation spreads to the coronet of heel portion, often make the special hoof wheel of heel wall emersion wave grain pattern, and it is narrow often to form heel.The general no change of whole body.Indivedual cases can be brought out the frog cancer because long-term corium exposes and stimulation repeatedly.
This disease spreads all over all over the world, and it is very extensive to distribute, and has the place of horse that the generation of this disease is just arranged.And the severe thrush for the treatment of horse does not have medicine and certain effectively Therapeutic Method preferably now, traditional medicine and method, and it is limited to produce effects.Therefore research and develop and a kind ofly treat the having no side effect of equus severe thrush, drug residue free, have no drug resistance and specific medicine is one of new problem anxious to be solved.The purpose of this invention is to provide a kind of equus severe thrush instant effect, good effect for the treatment of, the easy and medicine that has no side effect substantially of method.
Summary of the invention
The objective of the invention is to overcome the weak point on treatment equus severe thrush at present, provide a kind of draw materials easy, easy to prepare, reduce drug residue and toxic and side effects, and the medicine of the higher treatment equus severe thrush of cheap curative effect.
A kind of pharmaceutical composition for the treatment of equus severe thrush, its composition by weight is: salicylic acid powder 23-27 part, iodoform 4-6 part, Alumen 13-17 part, potassium permanganate powder 23-27 part, sulfa powder 8-12 part, Sanguis Draxonis powder 18-22 part;
Preferred composition by weight is:
18 parts of 27 parts of salicylic acid powder, 6 parts of iodoform, 13 parts in Alumen, 23 parts in potassium permanganate powder, sulfa powder 12, Sanguis Draxonis powder;
Or be:
23 parts of salicylic acid powder, 4 parts of iodoform, 17 parts in Alumen, 27 parts in potassium permanganate powder, 8 parts of sulfa powders, 22 parts of Sanguis Draxonis powder;
Or be:
25 parts of salicylic acid powder, 5 parts of iodoform, 15 parts in Alumen, 25 parts in potassium permanganate powder, 10 parts of sulfa powders, 20 parts of Sanguis Draxonis powder.
The present invention also provides a kind of medicine for the treatment of equus severe thrush, and it comprises: the aforesaid a kind of pharmaceutical composition for the treatment of equus severe thrush of A.; B. edible vegetable oil; C. pine tar;
Described edible vegetable oil is temperature 200-250 ℃.
A kind of pharmaceutical composition for the treatment of equus severe thrush provided by the invention is to adopt following method treatment:
1) at first will suffer from horse and properly in two post hurdles, to the uneasy trouble horse that is in a tumult, can use rather calmness of Baoding in Baoding.Take off the shoes of suffering from hoof, remove and suffer from hoof hoof bottom dirt, will suffer from hoof and put into the small rubber bucket, adding 5% Pearson's creolin. in the bucket, liquid volume added all are immersed in the liquid at the bottom of with whole hoof, and liquid is no more than coronet portion, and soak time is 45 minutes;
2) immersion finishes, and dries the back and conscientiously sterilizes with 5% iodine tincture,strong, eliminates rotten cutin and surperficial vegetation with hoof cutter or sharp spoon, strikes off slough, and up to exposing health tissues, 5% iodine tincture,strong is sterilized again, and gauze pressing stops blooding;
3) get 250 milliliters of edible oil of refining and water to rotten position, the oil of refining reaches the degree that a large amount of oil smoke occur, oily Wen Keda 220 degree.Deep fat is cleaned out oil after rotten place stops 25 minutes;
4) with a kind of treat horse severe thrush be pharmaceutical composition by weight component mix after being ground into fine powder, dip in the powder filling of the getting it filled position of rotting with cotton balls then, the situation of white cigarette and foaming can appear in the position of rotting this moment.Medicamental pulverata is inserted in the ditch seam of affected part as far as possible, and covered wound surface 2-3 millimeters thick, for the space larger part, the cotton balls that is stained with medicated powder together can be filled in, must the jam-pack plug real, cover sterile gauze then, the outside is coated with pine tar, and pad is played full hoof binder with roller, repaste the cloth pine tar, binding iron plate shoes.Must be with the meche jam-pack of the space at the bottom of iron plate shoes and the hoof, between the frog, and pour into a small amount of tar oil, in order to reach hemostasis by compression and antipollution purpose.Changed dressings once every 5 days, changed dressings once every 8 days after 20 days, if find to still have dysgonic superfluous granulating, wipe off with the tax spoon when changing dressings, after the drug of topical application, continue by last method binding ferrum meal shoes again.After treating all to form normal cutin, get final product drug withdrawal.Generally can form through 5-6 all new cutin approximately.Can carry out slight usage this moment, can carry out normal usage after the limping complete obiteration.
A kind of pharmaceutical composition for the treatment of equus severe thrush of the present invention.
Employed hot edible oil is Oleum Brassicae campestris, Oleum Arachidis hypogaeae semen or beans wet goods, and temperature will suit, and action wants fast during operation, but does not scald coronet and other positions will note watering oil the time.Hot Oleum Arachidis hypogaeae semen can bactericidal antiphlogistic, horny layer softening, and the blood vessel at the position of rotting is had anastalsis, also can dispel hypertrophy portion, suppresses to be converted into the hoof cancer, and can promote local blood circulation, is conducive to the growth of hoof tips matter.
A kind of pharmaceutical composition for the treatment of equus severe thrush, salicylic acid is the extremely wide disinfection preservative of purposes in the side, is applied to thrush, the cutin that solubilized is rotted, the metabolism of promotion hoof tips matter; Iodoform has slowly lasting disinfective action, and special abnormal smells from the patient is arranged, and can prevent biting of mosquitos and flies; Cold in nature, the sour-puckery flavor of Alumen has stronger astriction, has hemostasis, dampness, antibacterial action in we; Potassium permanganate is strong oxidizer, has very strong sterilization, sterilization and antisepsis; Sulfa powder has sterilization, antiinflammatory and anastalsis; The good medicine that Sanguis Draxonis removing blood stasis and relieving pain, hemostasia and promoting granulation are treatment traumatic injury, traumatic hemorrhage, remove the rotten and let fresh grow.Full side's Six-element medicine share, and existing anticorrosion antiinflammation is conducive to dispeling and stopping blooding of hypertrophy again.
Can not descend water, herd and usage in the week after the medication, can be suitable lead Stroll, circulate to promote systemic blood, be conducive to the eliminating of affected part inflammatory products.Prevent the mew humidity, in time clear up feces, the trouble hoof is in the environment of dried and clean.
This method treatment cost is little, and operation technique is simple, is easy to grasp, and is one of Perfected process for the treatment of equus thrush.
Said medicine is through organic assembling, and dialectical compatibility and assisting a ruler in governing a country has mutually strengthened that this side removes the rotten and lets fresh grow, the effect of anti-inflammation hemostasia, thereby reaches the purpose of curing horse severe thrush.
The specific embodiment
Embodiment 1
Composition by weight: salicylic acid powder 27 grams, iodoform 6 grams, Alumen 13 grams, potassium permanganate powder 23 grams, sulfa powder 12 grams, Sanguis Draxonis powder 18 grams, 250 milliliters of Oleum Brassicae campestriss, pine tar 500 grams.
Embodiment 2
Composition by weight: salicylic acid powder 23 grams, iodoform 4 grams, Alumen 17 grams, potassium permanganate powder 27 grams, sulfa powder 8 grams, Sanguis Draxonis powder 22 grams, Oleum Brassicae campestris 250ml, pine tar 500 grams.
Embodiment 3
Composition by weight: salicylic acid powder 25 grams, iodoform 5 grams, Alumen 15 grams, potassium permanganate powder 25 grams, sulfa powder 10 grams, Sanguis Draxonis powder 20 grams, Oleum Brassicae campestris 250ml, pine tar 500 grams.
Embodiment 4
Weigh by embodiment 1,2 or 3 proportionings, solid drugs is ground into fine powder, mix, form that a kind of to treat equus severe thrush be pharmaceutical composition.
The clinical treatment test
1. method: select relatively large ranch and Derby three families and the out-patient treatment case of breeding stock more than 300, select equus 48 examples of suffering from the severe thrush altogether, wherein horse is 43,5 of mules, age 4-13 year.To suffer from poultry and be divided into five groups, be respectively of the present invention group, salicylic acid potassium permanganate group, Sanguis Draxonis Oleum Verniciae fordii cream group, iron staff mallet powder group and deep fat matched group.
1.1 of the present invention group: adopting embodiment 4 to make that a kind of to treat horse severe thrush be pharmaceutical composition, is to adopt following method treatment:
1) at first will suffer from horse and properly in two post hurdles, to the uneasy trouble horse that is in a tumult, can use rather calmness of Baoding in Baoding.Take off the shoes of suffering from hoof, remove and suffer from hoof hoof bottom dirt, will suffer from hoof and put into the small rubber bucket, adding 5% Pearson's creolin. in the bucket, liquid volume added all are immersed in the liquid at the bottom of with whole hoof, and liquid is no more than coronet portion, and soak time is 45 minutes.
2) immersion finishes, and dries the back and conscientiously sterilizes with 5% iodine tincture,strong, eliminates rotten cutin and surperficial vegetation with hoof cutter or sharp spoon, strikes off slough, and up to exposing health tissues, 5% iodine tincture,strong is sterilized again, and gauze pressing stops blooding.
3) get 250 milliliters of Oleum Brassicae campestriss of refining and water to rotten position, the oil of refining reaches the degree that a large amount of oil smoke occur, oily Wen Keda 220 degree.Deep fat is cleaned out oil after rotten place stops 25 minutes.
4) with a kind of treat horse severe thrush be pharmaceutical composition by weight component mix after being ground into fine powder, dip in the powder filling of the getting it filled position of rotting with cotton balls then.Medicamental pulverata is inserted in the ditch seam of affected part as far as possible, and covered wound surface 2-3 millimeters thick, must the jam-pack plug real, cover sterile gauze then, the outside is coated with pine tar, and pad is played full hoof binder with roller, repastes the cloth pine tar, binding iron plate shoes.Must be with the meche jam-pack of the space at the bottom of iron plate shoes and the hoof, between the frog, and pour into a small amount of tar oil, in order to reach hemostasis by compression and antipollution purpose.Changed dressings once every 5 days, changed dressings once every 8 days after 20 days, if find to still have dysgonic superfluous granulating, wipe off with the tax spoon when changing dressings, after the drug of topical application, continue by last method binding ferrum meal shoes again.After treating all to form normal cutin, get final product drug withdrawal.Generally can form through 5-6 all new cutin approximately.Can carry out slight usage this moment, can carry out normal usage after the limping complete obiteration.
1.2 salicylic acid potassium permanganate group: whole Therapeutic Method is identical with of the present invention group, is the medicine difference for the treatment of, and this group medicine is made up of salicylic acid powder and potassium permanganate powder, and its ratio is 1:1.
1.3 Sanguis Draxonis Oleum Verniciae fordii cream group: Baoding sterilization, wash affected part repeatedly with 1/1000 bromo geramine, the finishing hoof is thoroughly removed slough and pus dirt, washes repeatedly, dries with 3% carbolic acid solution then.Get Sanguis Draxonis 50 and restrain, Oleum Verniciae fordii 150 grams are brewed into Sanguis Draxonis Oleum Verniciae fordii cream with little fire, wait temperature and pour into the empty position of rotting, and fill the back and bandage with gauze bandage, and later folding removed in 10 days.Can carry out 2-3 time.
1.4 Radix aconiti szechenyiani powder group: with the dried root of Radix aconiti szechenyiani, the rough bark on surface of pruning, fine grinding is made powder and is bottled standby.Remove earlier and suffer from the corrupt and downright bad cutin of the sick hoof affected part of poultry, wash repeatedly with 0.1% potassium permanganate solution, until the horny layer wash clean, after waiting to dry, ready made Radix aconiti szechenyiani powder is spread on affected part (medicated powder can not be higher than at the bottom of the hoof), lighted candle, drip the liquid of waxing, medicated powder is enclosed in affected part (medicated powder has severe toxicity, prevents from spilling other animal of injury), got final product in 1～2 day with gauze parcel affected part.Generally once a day or medication every other day 1 time.
1.5 deep fat matched group: do not use any medicine, just adopt the first three items of of the present invention group of Therapeutic Method, carried out once in five days.
Table 1 is suffered from poultry grouping and main Therapeutic Method
2. criterion of therapeutical effect: the severe thrush of the Drug therapy horse for the treatment of horse severe thrush, whether efficacy determination mainly disappears according to the thrush symptom.Treating 40 days is a course for the treatment of, and concrete curative effect is divided into three grades:
Cure: the thrush symptom of horse all disappears;
Take a turn for the better: the thrush symptom of horse partly disappears;
Invalid: the thrush symptom of horse does not have obvious improvement.
3. result: suffer from poultry by different dosage regimens for 48, after the treatment through two courses for the treatment of, each therapeutic effect of organizing sees Table 2.
The poultry effect is suffered from the various therapeutic scheme treatments of table 2
By table 2 as seen, two groups of medicines have different therapeutic effect to the equus acaricide, and wherein best with of the present invention group of therapeutic effect, cure rate reaches 95.45%, and total effective rate 100.00%, the utmost point are significantly higher than other two groups (P＜0.01); Salicylic acid potassium permanganate takes second place, Radix aconiti szechenyiani powder group and Sanguis Draxonis Oleum Verniciae fordii cream group again, and deep fat treatment of control group effect is the poorest.Statistical result shows that each group difference is (P＜0.01) extremely significantly.
Though medicine flavour of a drug of the present invention are few, through organic assembling, dialectical compatibility and assisting a ruler in governing a country has mutually strengthened that this side removes the rotten and lets fresh grow, the effect of anti-inflammation hemostasia, thereby reaches the purpose of curing horse severe thrush.Facts have proved: use the present invention and treat equus severe thrush to have a cost little, operation technique is simple, is easy to advantages such as grasps, and without any side effects, evident in efficacy, is one of rotten ideal medicament for the treatment of frog.
Above-mentioned detailed description of the pharmaceutical composition of this treatment equus severe thrush being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (6)
1. pharmaceutical composition for the treatment of equus severe thrush, its composition by weight is: salicylic acid powder 23-27 part, iodoform 4-6 part, Alumen 13-17 part, potassium permanganate powder 23-27 part, sulfa powder 8-12 part, Sanguis Draxonis powder 18-22 part.
2. a kind of pharmaceutical composition for the treatment of equus severe thrush according to claim 1 is characterized in that: 18 parts of 27 parts of salicylic acid powder, 6 parts of iodoform, 13 parts in Alumen, 23 parts in potassium permanganate powder, sulfa powder 12, Sanguis Draxonis powder.
3. a kind of pharmaceutical composition for the treatment of equus severe thrush according to claim 1 is characterized in that: 23 parts of salicylic acid powder, 4 parts of iodoform, 17 parts in Alumen, 27 parts in potassium permanganate powder, 8 parts of sulfa powders, 22 parts of Sanguis Draxonis powder.
4. a kind of pharmaceutical composition for the treatment of equus severe thrush according to claim 1 is characterized in that: 25 parts of salicylic acid powder, 5 parts of iodoform, 15 parts in Alumen, 25 parts in potassium permanganate powder, 10 parts of sulfa powders, 20 parts of Sanguis Draxonis powder.
5. medicine for the treatment of equus severe thrush, it comprises: the described pharmaceutical composition of A. claim 1; B. edible vegetable oil; C. pine tar.
6. a kind of medicine for the treatment of equus severe thrush according to claim 5, described edible oil temperature is 200-250 ℃.
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| CN2013101400647A CN103191275A (en) | 2013-04-22 | 2013-04-22 | Pharmaceutical composition for treating serious thrush of equus animals |
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| CN2013101400647A CN103191275A (en) | 2013-04-22 | 2013-04-22 | Pharmaceutical composition for treating serious thrush of equus animals |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2600161C1 (en) * | 2015-05-19 | 2016-10-20 | Общество с ограниченной ответственностью Научно-технический центр "Химинвест" (ООО НТЦ "Химинвест") | Method of miliary dermatitis and otodectic mange treating in carnivores |
| CN106540178A (en) * | 2016-12-12 | 2017-03-29 | 张明 | It is a kind of to treat the Chinese medicine composition that Ungula Equi Asini pitches canker |
| CN106728897A (en) * | 2016-12-12 | 2017-05-31 | 张明 | A kind of Chinese medicine composition for treating frush rot |
-
2013
- 2013-04-22 CN CN2013101400647A patent/CN103191275A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 侯国芳等: "家畜蹄叉腐烂的防治", 《农村天地》 * |
| 温伟等: "水杨酸高锰酸钾粉配合菜籽油治疗赛马蹄叉腐烂", 《中国兽医杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2600161C1 (en) * | 2015-05-19 | 2016-10-20 | Общество с ограниченной ответственностью Научно-технический центр "Химинвест" (ООО НТЦ "Химинвест") | Method of miliary dermatitis and otodectic mange treating in carnivores |
| CN106540178A (en) * | 2016-12-12 | 2017-03-29 | 张明 | It is a kind of to treat the Chinese medicine composition that Ungula Equi Asini pitches canker |
| CN106728897A (en) * | 2016-12-12 | 2017-05-31 | 张明 | A kind of Chinese medicine composition for treating frush rot |
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Application publication date: 20130710 |