CN103170013B - 一种医用植入件 - Google Patents
一种医用植入件 Download PDFInfo
- Publication number
- CN103170013B CN103170013B CN201110440393.4A CN201110440393A CN103170013B CN 103170013 B CN103170013 B CN 103170013B CN 201110440393 A CN201110440393 A CN 201110440393A CN 103170013 B CN103170013 B CN 103170013B
- Authority
- CN
- China
- Prior art keywords
- medical
- porous
- embedded material
- biodegradable
- medical embedded
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000007943 implant Substances 0.000 title claims abstract description 41
- 239000000463 material Substances 0.000 claims abstract description 196
- 238000006065 biodegradation reaction Methods 0.000 claims abstract description 16
- 150000001875 compounds Chemical group 0.000 claims abstract description 7
- 229910052751 metal Inorganic materials 0.000 claims description 24
- 239000002184 metal Substances 0.000 claims description 24
- 239000002131 composite material Substances 0.000 claims description 13
- 238000010276 construction Methods 0.000 claims description 13
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical class OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 10
- 229910052758 niobium Inorganic materials 0.000 claims description 8
- 239000010955 niobium Substances 0.000 claims description 8
- GUCVJGMIXFAOAE-UHFFFAOYSA-N niobium atom Chemical compound [Nb] GUCVJGMIXFAOAE-UHFFFAOYSA-N 0.000 claims description 8
- 229910052715 tantalum Inorganic materials 0.000 claims description 8
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 claims description 8
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 7
- 238000007711 solidification Methods 0.000 claims description 7
- 230000008023 solidification Effects 0.000 claims description 7
- 239000010936 titanium Substances 0.000 claims description 7
- 229910052719 titanium Inorganic materials 0.000 claims description 7
- 229920001651 Cyanoacrylate Polymers 0.000 claims description 6
- 239000004952 Polyamide Substances 0.000 claims description 6
- 239000000919 ceramic Substances 0.000 claims description 6
- -1 condensing model Polymers 0.000 claims description 6
- 229920002627 poly(phosphazenes) Polymers 0.000 claims description 6
- 229920002647 polyamide Polymers 0.000 claims description 6
- 229920000728 polyester Polymers 0.000 claims description 6
- 229910001220 stainless steel Inorganic materials 0.000 claims description 6
- 239000010935 stainless steel Substances 0.000 claims description 6
- 229910017053 inorganic salt Inorganic materials 0.000 claims description 5
- 230000000295 complement effect Effects 0.000 claims description 4
- 239000008267 milk Substances 0.000 claims description 4
- 210000004080 milk Anatomy 0.000 claims description 4
- 235000013336 milk Nutrition 0.000 claims description 4
- 238000007747 plating Methods 0.000 claims description 4
- 230000012010 growth Effects 0.000 abstract description 8
- 230000001771 impaired effect Effects 0.000 abstract description 6
- 230000035876 healing Effects 0.000 abstract description 5
- 230000004071 biological effect Effects 0.000 abstract description 4
- 238000013329 compounding Methods 0.000 abstract 1
- 238000002513 implantation Methods 0.000 description 14
- 210000000988 bone and bone Anatomy 0.000 description 12
- 150000002739 metals Chemical class 0.000 description 6
- 230000008439 repair process Effects 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 239000011148 porous material Substances 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 230000017074 necrotic cell death Effects 0.000 description 2
- 230000011164 ossification Effects 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 241000282412 Homo Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- PGTXKIZLOWULDJ-UHFFFAOYSA-N [Mg].[Zn] Chemical compound [Mg].[Zn] PGTXKIZLOWULDJ-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003462 bioceramic Substances 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 238000011536 re-plating Methods 0.000 description 1
- 239000003870 refractory metal Substances 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 238000005245 sintering Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 210000000515 tooth Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
- A61L27/427—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of other specific inorganic materials not covered by A61L27/422 or A61L27/425
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Abstract
Description
Claims (10)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110440393.4A CN103170013B (zh) | 2011-12-26 | 2011-12-26 | 一种医用植入件 |
CN201410707693.8A CN104383602B (zh) | 2011-12-26 | 2011-12-26 | 一种医用植入件 |
CN201410706108.2A CN104324414B (zh) | 2011-12-26 | 2011-12-26 | 一种医用植入件 |
PCT/CN2012/074513 WO2013097383A1 (zh) | 2011-12-26 | 2012-04-23 | 一种医用植入件 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110440393.4A CN103170013B (zh) | 2011-12-26 | 2011-12-26 | 一种医用植入件 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410707693.8A Division CN104383602B (zh) | 2011-12-26 | 2011-12-26 | 一种医用植入件 |
CN201410706108.2A Division CN104324414B (zh) | 2011-12-26 | 2011-12-26 | 一种医用植入件 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103170013A CN103170013A (zh) | 2013-06-26 |
CN103170013B true CN103170013B (zh) | 2014-12-24 |
Family
ID=48630486
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410707693.8A Active CN104383602B (zh) | 2011-12-26 | 2011-12-26 | 一种医用植入件 |
CN201110440393.4A Active CN103170013B (zh) | 2011-12-26 | 2011-12-26 | 一种医用植入件 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410707693.8A Active CN104383602B (zh) | 2011-12-26 | 2011-12-26 | 一种医用植入件 |
Country Status (2)
Country | Link |
---|---|
CN (2) | CN104383602B (zh) |
WO (1) | WO2013097383A1 (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20160176107A1 (en) | 2014-12-18 | 2016-06-23 | Cardiac Pacemakers, Inc. | Fibrous joinery interface between structures |
CN107198600A (zh) * | 2016-03-18 | 2017-09-26 | 重庆润泽医药有限公司 | 一种椎体间脊柱植入体 |
CN106267361A (zh) * | 2016-08-29 | 2017-01-04 | 上海交通大学 | 一种医用可载药金属‑高分子梯度多孔复合材料 |
CN109893304B (zh) * | 2019-04-16 | 2021-03-23 | 南京医科大学附属逸夫医院 | 一种特定形态与结构的3d打印组织工程支架 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101007183A (zh) * | 2006-12-01 | 2007-08-01 | 华南理工大学 | 一种原位成孔自固化磷酸钙复合组织工程支架的制备方法 |
WO2008017170A1 (en) * | 2006-08-10 | 2008-02-14 | Ao Technology Ag | Biomedical polymer material for tissue repair and engineering |
CN101474428A (zh) * | 2009-01-16 | 2009-07-08 | 浙江普洛医药科技有限公司 | 聚酯增强可降解多孔硅酸钙复合支架材料、制备及用途 |
CN101983728A (zh) * | 2010-11-09 | 2011-03-09 | 厦门大学 | 贝壳多孔羟基磷灰石基骨修复材料及其制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE29822563U1 (de) * | 1998-12-18 | 1999-02-18 | Aesculap AG & Co. KG, 78532 Tuttlingen | Implantat |
CN1302820C (zh) * | 2005-09-16 | 2007-03-07 | 哈尔滨工程大学 | TiO2增强聚甲基丙烯酸羟乙酯骨组织支架及其制备方法 |
KR101289122B1 (ko) * | 2008-03-18 | 2013-07-23 | 한국보건산업진흥원 | 생체분해성 마그네슘계 합금으로 다공성 구조체의 기공이충진된 복합재 임플란트 및 이의 제조방법 |
CN101906549B (zh) * | 2010-08-17 | 2012-11-21 | 南京航空航天大学 | 基于多孔泡沫金属的嵌入式固体自润滑材料及其制备方法 |
-
2011
- 2011-12-26 CN CN201410707693.8A patent/CN104383602B/zh active Active
- 2011-12-26 CN CN201110440393.4A patent/CN103170013B/zh active Active
-
2012
- 2012-04-23 WO PCT/CN2012/074513 patent/WO2013097383A1/zh active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008017170A1 (en) * | 2006-08-10 | 2008-02-14 | Ao Technology Ag | Biomedical polymer material for tissue repair and engineering |
CN101007183A (zh) * | 2006-12-01 | 2007-08-01 | 华南理工大学 | 一种原位成孔自固化磷酸钙复合组织工程支架的制备方法 |
CN101474428A (zh) * | 2009-01-16 | 2009-07-08 | 浙江普洛医药科技有限公司 | 聚酯增强可降解多孔硅酸钙复合支架材料、制备及用途 |
CN101983728A (zh) * | 2010-11-09 | 2011-03-09 | 厦门大学 | 贝壳多孔羟基磷灰石基骨修复材料及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
CN104383602B (zh) | 2016-03-23 |
WO2013097383A1 (zh) | 2013-07-04 |
CN104383602A (zh) | 2015-03-04 |
CN103170013A (zh) | 2013-06-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Pei et al. | 3D printed titanium scaffolds with homogeneous diamond-like structures mimicking that of the osteocyte microenvironment and its bone regeneration study | |
Holzapfel et al. | How smart do biomaterials need to be? A translational science and clinical point of view | |
CN105877874B (zh) | 仿生设计类骨多孔骨制品及其制备方法 | |
US9700431B2 (en) | Orthopaedic implant with porous structural member | |
CN105031737B (zh) | 3d打印的数字化人工骨及其制备方法 | |
EP1357863B1 (en) | Compositions and methods for biomedical applications | |
US9616205B2 (en) | Drug delivery implants | |
CN204581484U (zh) | 一种具有三维贯通多孔结构的3d打印骨螺钉 | |
EP2772230B1 (en) | Fusion prosthesis for the axis | |
US9445902B2 (en) | Platform for soft tissue attachment | |
EP3064175A1 (en) | Orthopaedic implant with porous structural member | |
CN103170013B (zh) | 一种医用植入件 | |
CN104758042A (zh) | 一种具有三维贯通多孔结构的骨螺钉 | |
WO2014052187A1 (en) | Variable density implant and method | |
CN103357063A (zh) | 一种可引导骨生长的金属复合材料及其应用 | |
WO2010019807A1 (en) | Orthopaedic implant with spatially varying porosity | |
Shaunak et al. | The role of 3D modelling and printing in orthopaedic tissue engineering: a review of the current literature | |
WO2019104392A1 (en) | Modular tissue implants | |
CN103857415A (zh) | 由聚四氟乙烯的多孔三维结构体制成的牙科植入物、血管植入物和组织植入物 | |
CN103908357B (zh) | 一种人造骨骼结构 | |
CN208243822U (zh) | 一种3d打印复合磁性金属支架 | |
CN104324414B (zh) | 一种医用植入件 | |
CN108201635A (zh) | 一种关节软骨下骨修复用支架 | |
Chen et al. | Fabrication methods of porous tantalum metal implants for use as biomaterials | |
CN110215319A (zh) | 具有仿生功能的人工关节假体在制备大段骨缺损重建材料中的应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C53 | Correction of patent for invention or patent application | ||
CB02 | Change of applicant information |
Address after: 400042 Chongqing city Yubei District Qinye Road No. 9 Applicant after: Chongqing Runze Pharmaceutical Co., Ltd. Address before: 401120 Chongqing city Yubei District Shuangfeng Bridge Street Airport Road No. 296 Building 1 yuan and 7 2- store Applicant before: Chongqing Runze Medical Instruments Ltd. |
|
COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: CHONGQING RUNZE MEDICAL INSTRUMENTS LTD. TO: CHONGQING RUNZE PHARMACEUTICAL CO., LTD. |
|
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: CAI SHUFEN Free format text: FORMER OWNER: CHONGQING RUNZE PHARMACEUTICAL CO., LTD. Effective date: 20141125 |
|
C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 400042 YUBEI, CHONGQING TO: 325000 WENZHOU, ZHEJIANG PROVINCE |
|
TA01 | Transfer of patent application right |
Effective date of registration: 20141125 Address after: Five Lucheng District of Wenzhou City High Street Bridge in Zhejiang province 325000 No. 8 Room 401 Applicant after: Cai Shufen Address before: 400042 Chongqing city Yubei District Qinye Road No. 9 Applicant before: Chongqing Runze Pharmaceutical Co., Ltd. |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20151225 Address after: 400042 Chongqing city Yubei District Qinye Road No. 9 Patentee after: Chongqing Runze Pharmaceutical Co., Ltd. Address before: Five Lucheng District of Wenzhou City High Street Bridge in Zhejiang province 325000 No. 8 Room 401 Patentee before: Cai Shufen |