CN103156683B - Monitoring and tracking bipolar ablation - Google Patents

Monitoring and tracking bipolar ablation Download PDF

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Publication number
CN103156683B
CN103156683B CN201210544527.1A CN201210544527A CN103156683B CN 103156683 B CN103156683 B CN 103156683B CN 201210544527 A CN201210544527 A CN 201210544527A CN 103156683 B CN103156683 B CN 103156683B
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Prior art keywords
electrode
ablating electrode
ablating
operation pattern
probe
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CN201210544527.1A
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CN103156683A (en
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A.戈瓦里
A.C.阿尔特曼
Y.埃夫拉思
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Biosense Webster Israel Ltd
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Biosense Webster Israel Ltd
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Priority claimed from US13/326,456 external-priority patent/US10456196B2/en
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Abstract

The invention discloses the method and system that treatment abnormal electrocardiogram is movable, including: using probe, it has the first ablating electrode on the distal portions being arranged on described probe and the second ablating electrode and is arranged on the sensing electrode between described first ablating electrode and the second ablating electrode;Described probe is made to contact with heart tissue;And apply energy to melt target tissue along ablation path by described first ablating electrode and the second ablating electrode;Utilize described sensing electrode to monitor electrocardio-activity to detect described electrocardio-activity.After observing that described sensing electrode is no longer able to described electrocardio-activity be detected, terminate applying energy.

Description

Monitoring and tracking bipolar ablation
Background technology
Technical field
The present invention relates to intrusive mood medical treatment device.More particularly, it relates to use such device Carry out ablation tissue.
2. background technology
Use electric energy to melt bodily tissue to be well known in the art.Generally disappear with the following method Melt: apply alternating current to electrode being enough to destroy the power of target tissue, such as radio-frequency (RF) energy.Generally, Electrode is arranged on the distal head of the conduit inserted in person under inspection's body.Can use known in the art multiple not Distal head is followed the tracks of, such as by measuring coil generation external by person under inspection at distal head with mode Distal head is followed the tracks of in magnetic field.Conduit can be provided with one pole ablating electrode or bipolar ablation electrode.
U.S. Patent Application Publication No.20080275440 of Kratoska relates to providing about ablation The method of the feedback of result.Provide the method for obtaining the feedback about ablation of tissue result, described Method includes being formulated in target tissue from conduit by one or more pins, by the one or more pin At least one come delivery of energy to melt at least some of of target tissue in case formed melt stove, stop logical Cross the energy of at least one in the one or more pin to deliver and logical after energy delivers stopping Cross at least one in the one or more pin to measure tissue characteristics.Measured tissue characteristics can be Temperature or impedance.It addition, measured tissue characteristics can be used for determining is melted stove by what ablation was formed Volume.
Summary of the invention
According to embodiments of the invention, it is provided that for treating the method that abnormal electrocardiogram is movable, described side Method performs by the following: provide probe, and described probe has on the distal portions being arranged on probe the One ablating electrode and the second ablating electrode and be arranged between the first ablating electrode and the second ablating electrode Sensing electrode;Probe is made to contact with the target tissue in person under inspection's heart;And by the first ablating electrode and Second ablating electrode applies energy to melt target tissue along ablation path.Described method is also by as follows Perform: upon application of energy, utilize sensing electrode to monitor electrocardio-activity and live to detect described electrocardio Move, observe that sensing electrode is no longer able to described electrocardio-activity detected and come in response to described observation Terminate applying energy.
According to another aspect of described method, described electrocardio-activity is that near field is movable.
According to another aspect of described method, between the E field and H field of electrocardio-activity, there are 90 ° Phase shift.
According to another aspect of described method, apply energy and be included in bipolar operation pattern and one pole behaviour Between operation mode alternately, under bipolar operation pattern, the first ablating electrode and the second ablating electrode serve as Bipolar electrode, under monopolar operation pattern, at least one in the first ablating electrode and the second ablating electrode is filled Work as monopolar electrode.
Another aspect of described method includes monitoring applying energy in the following way: graphically side Formula show a part for the described heart including target tissue figure and along described ablation path energy apply Process.
According to the additional aspect of described method, apply energy and be additionally included in bipolar operation pattern and one pole behaviour Between operation mode alternately, under bipolar operation pattern, the first ablating electrode and the second ablating electrode serve as Bipolar electrode, under monopolar operation pattern, at least one in the first ablating electrode and the second ablating electrode is filled Work as monopolar electrode, and wherein monitoring electrocardio-activity include figure described in labelling with instruction respectively with bipolar operation The Part I of the ablation path that pattern and monopolar operation pattern are associated and Part II.
An aspect according to described method, probe has and is arranged on the first ablating electrode and second and melts At least two sensing electrode between electrode.
According to other embodiments of the invention, additionally provide the equipment for implementing said method.
Accompanying drawing explanation
For being more fully understood that the present invention, provide detailed description of the invention by way of example.In conjunction with Detailed description read by lower accompanying drawing, and element identical in accompanying drawing represents by identical drawing reference numeral, and Wherein:
Fig. 1 is the diagram of the system for performing ablative surgery, and described system is the public affairs according to the present invention Open that embodiment constructs and be operable to;And
Fig. 2 is the electro-anatomical of the postero-anterior position projection of the heart standing to melt according to embodiments of the invention Figure.
Concrete executive mode
In order to fully understand the various principles of the present invention, elaborate many concrete thin in the following description Joint.However, it will be apparent to those skilled in the art that the most all these details are the most all It is carried out essential to the invention.In this case, in order to not make key concept unnecessarily become mould Stick with paste, be not shown specifically known to circuit, control logic and the computer journey for conventional algorithm and process Sequence order details.
The many aspects of the present invention may be embodied in software programming code, and described software programming code is usual It is maintained in permanent memory (such as computer-readable medium).In client/server environment In, this software programming code is storable in client or server.Software programming code may be embodied in Multiple known non-transitory medium (such as, floppy disk, the hard drive being used together with data handling system Device, electronic media or CD-ROM) in any one on.Described code can be distributed in this kind of medium On, or can by through certain form of network from the memorizer of a computer system to other computer Storage device in system and be distributed to user, the user for these other systems uses.
System explanation
Turning now to accompanying drawing, referring first to Fig. 1, it is at living subject or the heart of patient Performing the diagram of the system 10 of ablative surgery on 12, system 10 is according to disclosure of the invention embodiment Structure and be operable to.This system includes conduit 14, by operator 16 by conduit 14 via skin Skin passes in ventricle or the blood vessel structure of the vascular system insertion heart 12 of patient.Operator 16 is (generally For doctor) make the distal head 18 of conduit contact with heart wall at target spot melting.Then can be special according to the U.S. In profit No.6,226,542 and 6,301,496 and commonly assigned United States Patent (USP) No.6,892,091, institute is public The method opened prepares electrical activation figure, and disclosures of these patents is the most incorporated herein by reference.System A kind of commodity embodying element of system 10 are permissible3 systems are purchased from Biosense Webster, Inc. (3333Diamond Canyon Road, Diamond Bar, CA91765).
Can melt being such as assessed as abnormal region by electrical activation figure by applying heat energy, example As by radio-frequency current is conducted the one or more electricity to distal head 18 by the metal wire in conduit Pole, radio-frequency (RF) energy is applied to cardiac muscle by these electrodes.Energy is absorbed in tissue, thus is added by tissue Heat is to uniform temperature (normally about 50 DEG C), and tissue permanent can lose its electrostimulation at such a temperature Property.After this successful surgery, formed in heart tissue and non-conducting melt stove, these melt stove can in Break and cause ARR abnormal electric pathway.The principle of the present invention can be applied to different ventricles, application In sinus rhythm mapping, and apply when treating multiple different arrhythmia.
One pole melts and produces the deepest stove that melts being centrally located at ablating electrode position, and bipolar electric Pole tends to producing the shallower elongated ablation stove extended between a pair bipolar electrode.These bipolar ablation stoves Characteristic and position can to melt stove assessment and follow the tracks of produce difficulty.
Conduit 14 generally includes shank 20, has suitable controller so that operator 16 on shank Can be handled by far-end to conduit needed for ablative surgery, position and be oriented.For auxiliary operation person 16, the distal portions of conduit 14 includes aspect sensor (not shown), and it is to being positioned in control station 24 Location processor 22 signal is provided.
Ablation energy and the signal of telecommunication can be made to be placed through at distal head 18 by cable 34 or neighbouring by one Individual or multiple ablating electrodes 32, transmit between heart 12 and control station 24 back and forth.Cable can be passed through 34 and electrode 32 pacing signal and other control signal are sent to heart 12 from control station 24.Equally The sensing electrode 33 being connected to control station 24 is arranged between ablating electrode 32 and has been connected to cable 34.Melting period, ablating electrode 32 generally works under bi-polar configuration.But, in ablating electrode One or both can by use configuration circuit and be used as monopolar electrode, described configuration circuit be used for basis Ablation procedure is required and changes operator scheme between double pole mode and monopolar mode.
Other parts of control station 24 with external electrode 30 and positioning subsystem are connected to one by wiring 35 Rise.Electrode 32 and external electrode 30 can be used for measuring the tissue impedance at ablation points, as authorized United States Patent (USP) No.7 of Govari et al., as proposed in 536,218, this patent is with way of reference It is expressly incorporated herein.Mounting temperature sensor 37 on or near each electrode 32, usually thermoelectricity is the warmmest Sensitive resistor.
Control station 24 generally includes one or more ablation power generator 25.Conduit 14 may be adapted to profit By any of ablation techniques, by ablation energy, (such as, radio-frequency (RF) energy, ultrasonic energy and laser produce Luminous energy) conduction to heart.Commonly assigned United States Patent (USP) No.6,814,733, No.6,997,924 and No.7, discloses this type of method in 156,816, these patents are incorporated by reference herein.
Location processor 22 is the element of the positioning subsystem of system 10, and it measures the position of conduit 14 And orientation coordinate.
In one embodiment, positioning subsystem includes that structure is followed the tracks of in magnetic orientation, and this structure uses and generates The coil 28 in magnetic field, with predetermined working volume generate at magnetic field sensing tube about these Magnetic field, so that it is determined that the position of conduit 14 and orientation.
As it has been described above, conduit 14 is connected to control station 24, this control station makes operator 16 to see Examine and regulate and control the operation of conduit 14.Control station 24 includes processor, it is however preferred to have at suitable signal The computer of reason circuit.Described processor is connected to drive monitor 29.Signal processing circuit is usual Receiving, amplify, filter and digitized is from the signal of conduit 14, these signals include the sensor Signal produced by electrode (not shown) is sensed with the multiple positions being positioned at conduit 14 far-end.Control Platform 24 and positioning subsystem receive and use digitized signal, to calculate the location of conduit 14 and to be orientated also Analyze the signal of telecommunication of self-electrode.
Generally, system 10 includes other element, but these yuan are not shown for simplicity Part.Such as, system 10 can include electrocardiogram (ECG) monitor, and it is coupled to receive from one Or the signal of multiple external electrode, in order to provide ECG synchronization signal for control station 24.As it has been described above, System 10 generally also includes home position sensor, and it is positioned at the outside being connected to outside person under inspection's health Apply on benchmark paster, or be positioned at insertion heart 12 and be maintained at fixed position relative to heart 12 On built-in catheter.Provide for make liquid circulate through conduit 14 with cooling ablation points conventional pumps and Pipeline.
Conduit 14 generally includes one or more pairs of ablating electrode 32, as it is shown in figure 1, wherein sense electrode One or more in 33 are arranged between each pair of ablating electrode 32.Generally, ablating electrode 32 has There is larger area so that RF power is delivered to tissue effectively, and sensing electrode 33 can be relatively Little, as shown in the figure.In the ring electrode shown in Fig. 1, ablating electrode 32 should than sensing electrode 33 more Wide.
Although diagram embodiment includes two parallel type ring electrodes, but be used as single sense electrode or Use single driffractive ring to serve as a pair sensing electrode.Sensing electrode 33 senses the local electrical activity in heart And by means of suitably detecting with observation circuit (not shown) by detection electricity amplitude in control station 24 Decline follow the tracks of melt stove formed process.Therefore, a pair sensing electrode is preferably as it is permitted Permitted the bipolar measurement of the near field signal of telecommunication (there is between E field and H field the phase shift of 90 °), so that not having There is energy to be transmitted and therefore obtain more accurately indicating of local electrical activity.Disappearing by local electrical activity Lose to indicate and melt completely.Dynamically reconfigure ablating electrode 32 needed for melting stove according to generation Local requirement optionally to work under double pole mode and monopolar mode.
Melt monitoring
When bipolar ablation is carried out along path, follow the tracks of bipolar ablation the most to graphically, with Operator is made to may easily be determined line or time that ring is melted completely.Referring now to Fig. 2, according to it The expection of electro-anatomical Figure 37 of the postero-anterior position projection of the heart standing to melt of embodiments of the invention is real Example.Above-mentioned CARTO3 system can produce this figure.In this example, the region of plexus nervorum is comprised Marked by circle 39.These regions will guide to select the position melting stove 41 by melting establishment With orientation to treat arrhythmia, the such as arrhythmia being associated with complex fractionated AE.With In positioning and treating this ARR technology at commonly assigned co-pending patent application Proposing in No.12/275380, this patent application is incorporated by reference herein.Certainly, can be according to this Bright principle treats other arrhythmia multiple and abnormal conduction path.
When melt carry out time, follow the tracks of this process and it is shown as on Figure 37 a series of connect mark Note, the rectangle 43 wherein with intersection hatch patterns represents the interval of bipolar ablation, and is generally oriented The rectangle 45 becoming to be perpendicular to rectangle 43 represents the interval that one pole melts.Melt stove 41 to appear as linearly 's;But it is true not necessarily so.This melt stove can be curve or not even continuous print.Can be such as By graph technology (such as, color), rectangle 43 is distinguished with rectangle 45.
It will be appreciated by those skilled in the art that the present invention to be not limited to above and specifically illustrate and retouch The content stated.More precisely, the scope of the present invention includes combination and the subgroup of various feature mentioned above Close, and these features in the range of prior art, do not change and modifications form, these changes and repairing Reshaping formula be those skilled in the art after reading the above description it is contemplated that.

Claims (6)

1. an armarium, including:
Probe, described probe has the first ablating electrode on the distal portions being arranged on described probe and the second ablating electrode and is arranged on the sensing electrode between described first ablating electrode and the second ablating electrode;
It is connected to described first ablating electrode and the ablation energy generator of the second ablating electrode;And
Monitor, described monitor is connected to described sensing electrode and is operable to when described probe contacts with the target tissue in person under inspection's heart detect electrocardio-activity by described sensing electrode, described monitor includes that pictorial displays, described pictorial displays are operable to include the figure of a part for the described heart of described target tissue and the process of the energy applying along ablation path for display.
Equipment the most according to claim 1, wherein said electrocardio-activity is that near field is movable.
Equipment the most according to claim 1, wherein exists 90 between the E field and H field of described electrocardio-activity°Phase shift.
Equipment the most according to claim 1, also include configuring circuit, described configuration circuit is used for configuring described first ablating electrode and the second ablating electrode to work under bipolar operation pattern and monopolar operation pattern, under described bipolar operation pattern, described first ablating electrode and the second ablating electrode serve as bipolar electrode, and under described monopolar operation pattern, at least one in described first ablating electrode and the second ablating electrode serves as monopolar electrode.
Equipment the most according to claim 4, wherein said monitor is operable to for figure described in labelling to indicate Part I and the Part II of the ablation path being associated respectively with described bipolar operation pattern and described monopolar operation pattern.
Equipment the most according to claim 1, wherein said sensing electrode includes at least two sensing electrode being arranged between described first ablating electrode and the second ablating electrode.
CN201210544527.1A 2011-12-15 2012-12-14 Monitoring and tracking bipolar ablation Active CN103156683B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/326,456 2011-12-15
US13/326456 2011-12-15
US13/326,456 US10456196B2 (en) 2011-12-15 2011-12-15 Monitoring and tracking bipolar ablation

Publications (2)

Publication Number Publication Date
CN103156683A CN103156683A (en) 2013-06-19
CN103156683B true CN103156683B (en) 2016-11-30

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5404638A (en) * 1991-02-15 1995-04-11 Cardiac Pathways Corporation Method of forming a flexible expandable member for use with a catheter probe
US5579764A (en) * 1993-01-08 1996-12-03 Goldreyer; Bruce N. Method and apparatus for spatially specific electrophysiological sensing in a catheter with an enlarged ablating electrode
CN1187113A (en) * 1995-06-07 1998-07-08 生物感觉有限公司 Apparatus and method for treating cardiac arrhythmias with no discrete target
CN1193267A (en) * 1995-08-22 1998-09-16 得克萨斯州立大学董事会 Maneuverable electrophysiology catheter for percutaneous or intraoperative ablation of cardiac arrhythmias
US5954665A (en) * 1995-06-07 1999-09-21 Biosense, Inc. Cardiac ablation catheter using correlation measure
CN1652728A (en) * 2002-05-13 2005-08-10 导管治疗有限公司 An ablation catheter
CN101199416A (en) * 2006-09-06 2008-06-18 韦伯斯特生物官能公司 Correlation of cardiac electrical maps with body surface measurements

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5404638A (en) * 1991-02-15 1995-04-11 Cardiac Pathways Corporation Method of forming a flexible expandable member for use with a catheter probe
US5579764A (en) * 1993-01-08 1996-12-03 Goldreyer; Bruce N. Method and apparatus for spatially specific electrophysiological sensing in a catheter with an enlarged ablating electrode
CN1187113A (en) * 1995-06-07 1998-07-08 生物感觉有限公司 Apparatus and method for treating cardiac arrhythmias with no discrete target
US5954665A (en) * 1995-06-07 1999-09-21 Biosense, Inc. Cardiac ablation catheter using correlation measure
CN1193267A (en) * 1995-08-22 1998-09-16 得克萨斯州立大学董事会 Maneuverable electrophysiology catheter for percutaneous or intraoperative ablation of cardiac arrhythmias
CN1652728A (en) * 2002-05-13 2005-08-10 导管治疗有限公司 An ablation catheter
CN101199416A (en) * 2006-09-06 2008-06-18 韦伯斯特生物官能公司 Correlation of cardiac electrical maps with body surface measurements

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