CN103142956A - Medicine for treating viral myocarditis - Google Patents

Abstract

The invention relates to a medicine for treating viral myocarditis; the medicine is prepared from the following materials in parts by weight: 5-10 parts of radix scrophulariae, 10-20 parts of rhizoma zingiberis, 20-30 parts of dogwood, 10-20 parts of platycodon grandiflorum, 15-25 parts of radix angelicae, 5-15 parts of inula flower, 10-30 parts of cowherb seed, 1-15 parts of herba aristolochiae, 10-20 parts of radices sileris, 15-30 parts of ephedra, 20-30 parts of fructus chebulae, 1-20 parts of morinda officinalis, 1-20 parts of celandine, 10-25 parts of lalang grass rhizome, 10-30 parts of cocklebur fruit, 1-20 parts of emblic leafflower fruit, 15-20 parts of kamuning, 10-20 parts of kaladana, 15-20 parts of herba inulae, 15-30 parts of uniflower swisscentaury root, 15-25 parts of rhododendron dauricum, 15-25 parts of potentilla discolor, 10-20 parts of calyx seu fructus physalis, 15-25 parts of root bark of white mulberry, 20-30 parts of lindley eupatorium, 1-20 parts of Chinese mahonia stem and 10-25 parts of medulla stachyuri. The components of the medicine provided by the invention for treating viral myocarditis are all natural materials, and therefore the medicine is relatively excellent in safety, is exact in curative effect and is suitable for large-scale clinical promotion.

Description

A kind of medicament for the treatment of viral myocarditis

Technical field

The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of viral myocarditis.

Background technology

Viral myocarditis refer to by Coxsackie virus, dust can (ECHO), poliomyelitis, adenovirus, the influenza infection myocardium limitation or the diffuse acute or chronic inflammatory disease pathological changes that cause, belong to infectious cardiomyopathy.Virus function is directly to invade little blood vessel injury in cardiac muscle and cardiac muscle in the mode of cardiac muscle.Producing cardiac damage by immunologic mechanism plays an important role in myocarditic morbidity.The direct infringement of virus and immunoreation mediation cause the myocardial cell infringement, make heart systolic and diastolic function obstacle; If pathological changes is involved pace-making or the conducting systems such as sinuatrial node, atrioventricular node, bundle branch, can cause various types of arrhythmia.In addition, primary disease also may be relevant with selenium deficiency and HLA class antigen abnormal expression.The myocarditis that is caused by infection of Coxsackie B virus finally approximately 10% develops into dilated cardiomyopathy.Patient often first has the symptoms such as heating, systemic pain, pharyngalgia, asthenia, nausea,vomiting,diarrhea, cardiopalmus, uncomfortable in chest, chest pain or pareordia dull pain, dizziness, dyspnea, edema, even Adams-Stokes syndrome then occur; Heart failure or cardiogenic shock appear in only a few patient.At present, in the urgent need to a kind of medicine of effective treatment viral myocarditis.

Summary of the invention

The purpose of this invention is to provide a kind of medicament for the treatment of viral myocarditis.

in order to realize purpose of the present invention, the invention provides a kind of medicament for the treatment of viral myocarditis, it is to be made by the material of following weight proportioning: Radix Scrophulariae 5-10 part, Rhizoma Zingiberis 10-20 part, Fructus Corni 20-30 part, Radix Platycodonis 10-20 part, Radix Angelicae Dahuricae 15-25 part, Flos Inulae 5-15 part, Semen Vaccariae 10-30 part, Herba Aristolochiae 1-15 part, Radix Saposhnikoviae 10-20 part, Herba Ephedrae 15-30 part, Fructus Terminaliae Billericae 20-30 part, Radix Morindae Officinalis 1-20 part, Herba Chelidonii 1-20 part, Rhizoma Imperatae 10-25 part, Fructus Xanthii 10-30 part, Fructus Phyllanthi 1-20 part, Folium Et Cacumen Murrayae 15-20 part, Semen Pharbitidis 10-20 part, Herba Inulae 15-20 part, Herba Sarcandrae 15-30 part, Herba Clinopodii 10-20 part, Folium Sennae 10-25 part, Radix seu Herba Gei aleppici 5-15 part, Radix Rhapontici 1-20 part, Folium Rhododendri Daurici 15-25 part, Herba Potentillae Discoloris 15-25 part, Calyx Seu Fructus Physalis 10-20 part, Cortex Mori 15-25 part, Herba Eupatorii Lindleyani 20-30 part, Caulis Mahoniae 1-20 part and Medulla Stachyuri (Medulla Helwingiae) 10-25 part.

preferably, the medicament for the treatment of viral myocarditis of the present invention is to be made by the material of following weight proportioning: 7 parts of Radix Scrophulariaes, 13 parts of Rhizoma Zingiberiss, 22 parts of Fructus Corni, 15 parts of Radix Platycodoniss, 21 parts of the Radixs Angelicae Dahuricae, 13 parts of Flos Inulaes, 28 parts of Semen Vaccariae, 11 parts of Herba Aristolochiaes, 17 parts of Radix Saposhnikoviaes, 24 parts, Herba Ephedrae, 27 parts of Fructus Terminaliae Billericaees, 18 parts of Radix Morindae Officinaliss, 17 parts of Herba Chelidoniis, 23 parts of Rhizoma Imperataes, 21 parts of Fructus Xanthii, 16 parts of Fructus Phyllanthis, 16 parts of Folium Et Cacumen Murrayae, 17 parts of Semen Pharbitidiss, 19 parts of Herba Inulae, 15 parts of Herba Sarcandraes, 14 parts of Herba Clinopodii, 21 parts of Folium Sennae, 11 parts of Radix seu Herba Gei aleppici, 13 parts of Radix Rhapontici, 23 parts of Folium Rhododendri Daurici, 24 parts of Herba Potentillae Discoloris, 14 parts of Calyx Seu Fructus Physaliss, 25 parts of Cortex Mori, 26 parts of Herba Eupatorii Lindleyanis, 24 parts of 16 parts of Caulis Mahoniaes and Medulla Stachyuri (Medulla Helwingiae)s.

More preferably, described medicament can be tablet, dispersible tablet, capsule or decoction.

Whole compositions of the medicament for the treatment of viral myocarditis of the present invention are all natural materials, and safety is better, and curative effect is clear and definite, are suitable for large-scale promotion clinically.

The specific embodiment

Further illustrate the present invention below by embodiment.It should be understood that embodiments of the invention are for explanation the present invention rather than limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Except as otherwise noted, otherwise the percent in the present invention is percetage by weight.

Embodiment decoction of the present invention

take Radix Scrophulariae 7 grams, Rhizoma Zingiberis 13 grams, Fructus Corni 22 grams, Radix Platycodonis 15 grams, the Radix Angelicae Dahuricae 21 grams, Flos Inulae 13 grams, Semen Vaccariae 28 grams, Herba Aristolochiae 11 grams, Radix Saposhnikoviae 17 grams, Herba Ephedrae 24 grams, Fructus Terminaliae Billericae 27 grams, Radix Morindae Officinalis 18 grams, Herba Chelidonii 17 grams, Rhizoma Imperatae 23 grams, Fructus Xanthii 21 grams, Fructus Phyllanthi 16 grams, Folium Et Cacumen Murrayae 16 grams, Semen Pharbitidis 17 grams, Herba Inulae 19 grams, Herba Sarcandrae 15 grams, Herba Clinopodii 14 grams, Folium Sennae 21 grams, Radix seu Herba Gei aleppici 11 grams, Radix Rhapontici 13 grams, Folium Rhododendri Daurici 23 grams, Herba Potentillae Discoloris 24 grams, Calyx Seu Fructus Physalis 14 grams, Cortex Mori 25 grams, Herba Eupatorii Lindleyani 26 grams, Caulis Mahoniae 16 grams and Medulla Stachyuri (Medulla Helwingiae) 24 grams, add 2000 milliliters of entry, in being housed, heated 4 hours under 80 ℃ by the flask of condensing tube, filter.Filtrate is concentrated into 600 milliliters, namely gets decoction of the present invention.

Experimental example

Case selects 120 routine patients all to meet the 7th edition internal medicine diagnosis of viral myocarditis standard, male 64 examples wherein, female's 56 examples, 13～54 years old age; Upper respiratory tract infection history 75 examples are arranged.Heating shower 81 examples are arranged, weak 95 examples, uncomfortable in chest, cardiopalmus 82 examples, precordialgia, pale complexion 62 examples, nausea and vomiting 39 examples in 120 routine patients.The routine blood test numeration of leukocyte is: 4.1～15.3x10 ⁹/ L, wherein leucocytosis＞10.0x10 ⁹/ L32 example, acute stage erythrocyte sedimentation rate rising 48 examples, serum creatine kinase isoenzyme rising 59 examples.It is low flat or be inverted that patient with slight symptoms's electrocardiogram often shows as the T ripple, and the ST section can appear in limb lead low-voltage, severe one to be forced down even myocardial infarction sample ST section and raise or abnormality Q wave, various arrhythmia can occur.

Treat with the decoction that makes in embodiment 1, wherein one day 3 times, each oral 150 milliliters, treating January is a course for the treatment of.Check blood, routine urinalysis, blood glucose, blood fat, hepatic and renal function, myocardium enzyme, electrolyte and electrocardiogram in the course of disease.

Curative effect determinate standard

Produce effects: symptom and sign disappears substantially, and lab testing is normal, and it is normal that electrocardiogram recovers, and effectively: clinical symptoms partly disappears, and sign and lab testing are improved, and electrocardiogram takes a turn for the better; Invalid: clinical symptoms, sign and every coherence check are without improvement.

Through the treatment of a course for the treatment of, find that 120 patient's symptom and signs disappear substantially, lab testing is normal, and it is normal that electrocardiogram recovers, and therefore all meets the curative effect determinate standard of produce effects.

All the patient is followed up a case by regular visits to weekly after treating a course for the treatment of, continue half a year, find the sign of recurrence.

Claims (3)

1. medicament for the treatment of viral myocarditis, it is characterized in that, it is to be made by the material of following weight proportioning: Radix Scrophulariae 5-10 part, Rhizoma Zingiberis 10-20 part, Fructus Corni 20-30 part, Radix Platycodonis 10-20 part, Radix Angelicae Dahuricae 15-25 part, Flos Inulae 5-15 part, Semen Vaccariae 10-30 part, Herba Aristolochiae 1-15 part, Radix Saposhnikoviae 10-20 part, Herba Ephedrae 15-30 part, Fructus Terminaliae Billericae 20-30 part, Radix Morindae Officinalis 1-20 part, Herba Chelidonii 1-20 part, Rhizoma Imperatae 10-25 part, Fructus Xanthii 10-30 part, Fructus Phyllanthi 1-20 part, Folium Et Cacumen Murrayae 15-20 part, Semen Pharbitidis 10-20 part, Herba Inulae 15-20 part, Herba Sarcandrae 15-30 part, Herba Clinopodii 10-20 part, Folium Sennae 10-25 part, Radix seu Herba Gei aleppici 5-15 part, Radix Rhapontici 1-20 part, Folium Rhododendri Daurici 15-25 part, Herba Potentillae Discoloris 15-25 part, Calyx Seu Fructus Physalis 10-20 part, Cortex Mori 15-25 part, Herba Eupatorii Lindleyani 20-30 part, Caulis Mahoniae 1-20 part and Medulla Stachyuri (Medulla Helwingiae) 10-25 part.

2. the medicament for the treatment of viral myocarditis according to claim 1, it is characterized in that, it is to be made by the material of following weight proportioning: 7 parts of Radix Scrophulariaes, 13 parts of Rhizoma Zingiberiss, 22 parts of Fructus Corni, 15 parts of Radix Platycodoniss, 21 parts of the Radixs Angelicae Dahuricae, 13 parts of Flos Inulaes, 28 parts of Semen Vaccariae, 11 parts of Herba Aristolochiaes, 17 parts of Radix Saposhnikoviaes, 24 parts, Herba Ephedrae, 27 parts of Fructus Terminaliae Billericaees, 18 parts of Radix Morindae Officinaliss, 17 parts of Herba Chelidoniis, 23 parts of Rhizoma Imperataes, 21 parts of Fructus Xanthii, 16 parts of Fructus Phyllanthis, 16 parts of Folium Et Cacumen Murrayae, 17 parts of Semen Pharbitidiss, 19 parts of Herba Inulae, 15 parts of Herba Sarcandraes, 14 parts of Herba Clinopodii, 21 parts of Folium Sennae, 11 parts of Radix seu Herba Gei aleppici, 13 parts of Radix Rhapontici, 23 parts of Folium Rhododendri Daurici, 24 parts of Herba Potentillae Discoloris, 14 parts of Calyx Seu Fructus Physaliss, 25 parts of Cortex Mori, 26 parts of Herba Eupatorii Lindleyanis, 24 parts of 16 parts of Caulis Mahoniaes and Medulla Stachyuri (Medulla Helwingiae)s.

3. the medicament for the treatment of viral myocarditis according to claim 1, is characterized in that, described medicament can be tablet, dispersible tablet, capsule or decoction.