CN103111018B - Skin dosing close patch - Google Patents
Skin dosing close patch Download PDFInfo
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- CN103111018B CN103111018B CN201310068223.7A CN201310068223A CN103111018B CN 103111018 B CN103111018 B CN 103111018B CN 201310068223 A CN201310068223 A CN 201310068223A CN 103111018 B CN103111018 B CN 103111018B
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- skin
- drug delivery
- medicine
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- percutaneous drug
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Abstract
The invention relates to a skin dosing close patch. The skin dosing close patch comprises a stickup layer (1) and a drug filling tank (2) which is arranged at the center of the stickup layer (1), wherein a plastic washer (3) is arranged on the edge of one side, close to the stickup layer (1), of the drug filling tank (2). When the skin dosing close patch is used, the plastic washer (3) is attached tightly to the skin. The skin dosing close patch separates the drug from the outside, the drug is hard to volatilize, and the skin dosing close patch can be loaded with liquid drug, the liquid drug cannot flow out, the drug effect is kept, and an ideal dosing effect is achieved.
Description
Technical field
The present invention relates to a kind of percutaneous drug delivery and close subsides.
Background technology
At present, along with development that is biological and pharmaceutical technology, zoopery has become a kind of infrastest method of biology and medical science, medicine in clinical practice before human body, usually all need by means of some laboratory animals, as mice, rat, rabbit, dog etc., the pharmacodynamics of medicine, pharmacology and toxicology etc. are studied.
In some local excitations or hypersensitive test, need the administration carrying out the long period on the skin of laboratory animal, on the one hand, because laboratory animal has good automatic control unlike people, the cooperate degree of people can not be reached, need experimental implementation person that testing drug is fixed on laboratory animal skin surface all the time, in order to avoid drug loss affects test result, comparatively bother during experimental implementation, expend time in; Some medicines have volatility on the other hand, and especially liquid medicine has mobility, and therefore in administration process, medicine can volatilize or flow out agents area, does not reach and tests effect preferably.
Authorization Notice No. is disclose a kind of Enepidermic application in the utility model patent of CN201987755U, it comprises elastic force adhesive plaster and absorbent cotton layer, this Enepidermic application can spill solid drugs or liquid medicine in advance in use on absorbent cotton layer, applied in skin affected part, be attached to skin by glue and be fixed.But use this Enepidermic application, need to be sprinkled upon by medicine on absorbent cotton layer in advance, absorbent cotton layer can absorb a part of medicine, causes the loss of medicine.
Authorization Notice No. is disclose a kind of human body surface administration plaster in the utility model patent of CN2252007Y, and the medicine that can load has lamellar, Powdered, pasty state, paste, but can not loading liquid medicine.
Summary of the invention
For above shortcomings in prior art, technical problem to be solved by this invention is to provide a kind of percutaneous drug delivery and closes subsides.
The present invention seeks to be achieved through the following technical solutions:
A kind of percutaneous drug delivery is closed and is pasted, and has an adhered layer 1, and the center on described adhered layer 1 has one and contains medicine groove 2.
Close as the preferred percutaneous drug delivery of one and paste, the edge of the close skin side of described Sheng medicine groove 2 has plastic washer 3, and when using described percutaneous drug delivery to close subsides, plastic washer 3 and skin are adjacent to.
Preferably,
Described Sheng medicine groove 2 is the square of 1.5cm × 1.5cm ~ 2.5cm × 2.5cm or diameter is the circle of 1.5 ~ 2.5cm.
Described adhered layer is hypo-allergenic adhesive plaster.
Can medicine be placed with in Sheng medicine groove 2, during use, described medicine and contact skin.
Described medicine is preferably liquid medicine.
It is preferred further,
Have the first cylindrical body 4 in described Sheng medicine groove 2, its height is highly identical with Sheng medicine groove 2, and the first cylindrical body 4 is uncovered near skin one end.
Described first cylindrical body 4 passes Sheng medicine groove 2 away from one end of skin, and the both sides making percutaneous drug delivery close subsides are connected, and the first cylindrical body 4 has block away from one end of skin.
Also oriented the second cylindrical body 5 away from skin side projection on described Sheng medicine groove 2, the both sides making percutaneous drug delivery close subsides are connected, and the second cylindrical body 5 has block away from one end of skin.
In use, the block in the first cylindrical body 4 can be opened, liquid or body of paste medicine is come by the first cylindrical body 4, after administration, the first cylindrical body 4 is near skin side and skin close contact, and medicine is centered by the first cylindrical body 4 with contact skin point, can along skin dispersed, now, open the block of the second cylindrical body 5, get rid of the additional air contained in medicine groove 2.
Also can open the block of the second cylindrical body 5, say that powdery medicine is poured into by the second cylindrical body and contain in medicine groove 2.
Compared with prior art, tool has the following advantages in the present invention:
1, the percutaneous drug delivery of the present invention's design is closed and is pasted, and medicine is separated with extraneous, not volatile, keeps drug effect, reaches desirable administering effect;
2, the percutaneous drug delivery of the present invention's design is closed and is pasted, and can make to carry out accurate administration to medicine-feeding part, prevent the pollution beyond to medicine-feeding part, safety and sanitation;
3, the percutaneous drug delivery of the present invention's design is closed and is pasted, and can take up the medicine of most dosage form, liquid medicine, liquid medicine can not flow out;
4, after giving medicine, with the activity of laboratory animal, medicine can rock in Sheng medicine groove, plays each drug molecule or granule all has the chance with contact skin.
Accompanying drawing explanation
Fig. 1 is the perspective view that the percutaneous drug delivery of embodiment 1 closes subsides.
Fig. 2 is the main TV structure schematic diagram that the percutaneous drug delivery of embodiment 1 closes subsides.
Fig. 3 is the perspective view that the percutaneous drug delivery of embodiment 2 closes subsides.
Fig. 4 is the perspective view that the percutaneous drug delivery of embodiment 3 closes subsides.
Fig. 5 is the main TV structure schematic diagram that the percutaneous drug delivery of embodiment 3 closes subsides.
Description of reference numerals: 1, adhered layer; 2, medicine groove is contained; 3, plastic washer; 4, the first cylindrical body; 5, the second cylindrical body.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.Defining in the present invention is inner side near skin side in use, and rightabout is outside.
Embodiment 1
As illustrated in fig. 1 and 2, close for a kind of percutaneous drug delivery and paste, there is an adhered layer 1, adhered layer 1 is hypo-allergenic adhesive plaster, center on described adhered layer 1 has one and contains medicine groove 2, the edge of close adhered layer 1 side of described Sheng medicine groove 2 has plastic washer 3, and described Sheng medicine is the square of 1.5cm × 1.5cm.
When using described percutaneous drug delivery to close subsides, put into by tablet medicine and contain medicine groove 2, plastic washer 3 and skin are adjacent to, by the skin around hypo-allergenic rubberized fabric adhere and medicine-feeding part.
Embodiment 2
As shown in Figure 3, close for a kind of percutaneous drug delivery and paste, there is an adhered layer 1, adhered layer 1 is hypo-allergenic adhesive plaster, center on described adhered layer 1 has one and contains medicine groove 2, the edge of close adhered layer 1 side of described Sheng medicine groove 2 has plastic washer 3, and described plastic washer 3 is the square of 2.5cm × 2.5cm.
Have the first cylindrical body 4 in described Sheng medicine groove 2, its height is highly identical with Sheng medicine groove 2, and the first cylindrical body 4 is uncovered near skin one end.
Closed by percutaneous drug delivery after pasting and being pasted on the skin of medicine-feeding part, plastic washer 3 and skin are adjacent to, and open the block of the first cylindrical body 4, body of paste medicine is put into by the first cylindrical body 4 and contains medicine groove 2, build block, described body of paste medicine and contact skin, can not flow out.
Embodiment 3
As shown in Figures 4 and 5, close for a kind of percutaneous drug delivery and paste, there is an adhered layer 1, adhered layer 1 is hypo-allergenic adhesive plaster, center on described adhered layer 1 has one and contains medicine groove 2, the edge of close adhered layer 1 side of described Sheng medicine groove 2 has plastic washer 3, and described plastic washer 3 is the square of 2cm × 2cm.
Have the first cylindrical body 4 in described Sheng medicine groove 2, its height is highly identical with Sheng medicine groove 2, and the first cylindrical body 4 is uncovered near skin one end.
Described first cylindrical body 4 passes Sheng medicine groove 2 away from one end of skin, and the both sides making percutaneous drug delivery close subsides are connected, and the first cylindrical body 4 has block away from one end of skin.
Also oriented the second cylindrical body 5 away from skin side projection on described Sheng medicine groove 2, the both sides making percutaneous drug delivery close subsides are connected, and the second cylindrical body 5 has block away from one end of skin.
Percutaneous drug delivery is closed paste be pasted on the skin of medicine-feeding part after, plastic washer 3 and skin are adjacent to, open the block of the first cylindrical body 4, liquid medicine is put into by the first cylindrical body 4 and contains medicine groove 2, build block, described liquid medicine and contact skin, medicine is centered by the first cylindrical body 4 with contact skin point, along skin dispersed, can not close volatilization or outflow subsides from percutaneous drug delivery.Open the block of the second cylindrical body 2, unnecessary air is discharged.
The present invention can be applicable to the laboratory animals such as new zealand rabbit, rat, Cavia porcellus, dog and monkey.
The above; be only the specific embodiment of the present invention; but protection scope of the present invention is not limited thereto; any those of ordinary skill in the art are in the technical scope disclosed by the present invention; the change can expected without creative work or replacement, all should be encompassed within protection scope of the present invention.Therefore, the protection domain that protection scope of the present invention should limit with claims is as the criterion.
Claims (6)
1. a percutaneous drug delivery is closed and is pasted, and it is characterized in that: have an adhered layer (1), and the center on described adhered layer (1) has one and contains medicine groove (2); The edge of the close skin side of described Sheng medicine groove (2) has plastic washer (3), and when using described percutaneous drug delivery to close subsides, plastic washer (3) and skin are adjacent to; Have the first cylindrical body (4) in described Sheng medicine groove (2), its height is highly identical with Sheng medicine groove (2), and the first cylindrical body (4) is uncovered near skin one end; Upper oriented the second cylindrical body (5) away from skin side projection of described Sheng medicine groove (2), the both sides making percutaneous drug delivery close subsides are connected, and the second cylindrical body (5) has block away from one end of skin.
2. percutaneous drug delivery as claimed in claim 1 is closed and is pasted, and it is characterized in that: the square that described Sheng medicine groove (2) is 1.5cm × 1.5cm ~ 2.5cm × 2.5cm or diameter are the circle of 1.5 ~ 2.5cm.
3. percutaneous drug delivery as claimed in claim 1 is closed and is pasted, and it is characterized in that: described adhered layer (1) is hypo-allergenic adhesive plaster.
4. percutaneous drug delivery as claimed in claim 1 is closed and is pasted, and it is characterized in that: in Sheng medicine groove (2), be placed with medicine, during use, and described medicine and contact skin.
5. percutaneous drug delivery as claimed in claim 4 is closed and is pasted, and it is characterized in that: described medicine is liquid medicine.
6. percutaneous drug delivery as claimed in claim 1 is closed and is pasted, it is characterized in that: described first cylindrical body (4) passes Sheng medicine groove (2) away from one end of skin, the both sides making percutaneous drug delivery close subsides are connected, and the first cylindrical body (4) has block away from one end of skin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310068223.7A CN103111018B (en) | 2013-03-04 | 2013-03-04 | Skin dosing close patch |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310068223.7A CN103111018B (en) | 2013-03-04 | 2013-03-04 | Skin dosing close patch |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103111018A CN103111018A (en) | 2013-05-22 |
| CN103111018B true CN103111018B (en) | 2015-03-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310068223.7A Active CN103111018B (en) | 2013-03-04 | 2013-03-04 | Skin dosing close patch |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103111018B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US697637A (en) * | 1901-11-12 | 1902-04-15 | John Ellwood Lee | Shield for vaccinations, &c. |
| CN1089168A (en) * | 1992-10-30 | 1994-07-13 | 梅地普洛科学有限公司 | The material delivery systems of local application |
| EP0842647A1 (en) * | 1996-11-13 | 1998-05-20 | MACIOCIA, Yves | Adhesive occlusive device permitting the dispensing of different active agents after application to the skin |
| CN201987755U (en) * | 2011-02-28 | 2011-09-28 | 李霞 | Enepidermic application |
| CN203107993U (en) * | 2013-03-04 | 2013-08-07 | 上海市计划生育科学研究所 | Skin drug delivery closing stickup bandage |
-
2013
- 2013-03-04 CN CN201310068223.7A patent/CN103111018B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US697637A (en) * | 1901-11-12 | 1902-04-15 | John Ellwood Lee | Shield for vaccinations, &c. |
| CN1089168A (en) * | 1992-10-30 | 1994-07-13 | 梅地普洛科学有限公司 | The material delivery systems of local application |
| EP0842647A1 (en) * | 1996-11-13 | 1998-05-20 | MACIOCIA, Yves | Adhesive occlusive device permitting the dispensing of different active agents after application to the skin |
| CN201987755U (en) * | 2011-02-28 | 2011-09-28 | 李霞 | Enepidermic application |
| CN203107993U (en) * | 2013-03-04 | 2013-08-07 | 上海市计划生育科学研究所 | Skin drug delivery closing stickup bandage |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103111018A (en) | 2013-05-22 |
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Address after: 200032 Shanghai Xuhui District Xietu Road No. 2140 Patentee after: Shanghai Institute of biomedical technology Address before: 200032 Shanghai Xuhui District Xietu Road No. 2140 Patentee before: SHANGHAI INSTITUTE OF PLANNED PARENTHOOD RESEARCH |
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| CP01 | Change in the name or title of a patent holder |