CN104043192B - Disposable microneedle devices - Google Patents
Disposable microneedle devices Download PDFInfo
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- CN104043192B CN104043192B CN201410296973.4A CN201410296973A CN104043192B CN 104043192 B CN104043192 B CN 104043192B CN 201410296973 A CN201410296973 A CN 201410296973A CN 104043192 B CN104043192 B CN 104043192B
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- pedestal
- micropin
- base
- connecting rod
- microneedle
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Abstract
Disposable microneedle devices includes base, microneedle component, lid and some connecting rods being dissolvable in water ethanol；This microneedle component includes pedestal and the micropin some spaced apart being located on pedestal；The roof of this pedestal with respectively offer the conical socket that quantity is identical with connecting rod on the diapire of this base；The two the most tapered shapes of end of each connecting rod, a wherein end of each connecting rod is flush-mounted in correspondence one conical socket of the diapire of this base, and another end of each connecting rod is flush-mounted in correspondence one conical socket of the roof of this pedestal；Some connecting rods are spaced formation one Triangular array；This lid is removably fastened on this base, forms a confined space between this lid and this base, and this microneedle component and connecting rod are positioned at this confined space.Foregoing invention can effectively prevent secondary from using, and fundamentally avoids cross infection.
Description
Technical field
The present invention relates to a kind of disposable microneedle devices.
Background technology
Owing to the micropin of microneedle devices is sharp short and small, and keratodermatitis does not has nervous tissue and blood vessel, when therefore using
Pain and bleeding will not be produced, and the aperture of Wicresoft can heal within a very short time, so that microneedle devices is the most extensive
It is applied to therapeutic administration, is also widely used for promoting absorption and the infiltration of cosmetics.
Existing microneedle devices generally comprises base and microneedle array package, and this microneedle array package is fixed on by viscose
On this base.In actual application, some beauty parlor is cost-effective, can be by used microneedle devices through ethanol simply immersing
After reuse, so, the risk of cross infection can be brought to user, the most then skin allergy as being dried, red and swollen, heavy then disfeature
Or infection infectious disease.It addition, by observing intuitively, user also cannot differentiate that microneedle devices used the most, it is unfavorable for dimension
Protect self lawful right.
When user is administered by microneedle devices, typically press microneedle array so that microneedle array moment is at skin keratin
Layer and epidermal area produce the duct of a large amount of micron dimension sizes, then take microneedle devices away, and medicine is applied in skin, and medicine can lead to
The duct crossing skin realizes rapid osmotic and diffusion, and this kind of mode sometimes results in medicine and polluted by the impurity in air, shadow
Ring drug effect, and operational efficiency is relatively low.
Summary of the invention
For the deficiencies in the prior art, the purpose of the present invention be intended to provide a kind of prevent that secondary from using the most micro-
Needle device.
For achieving the above object, the present invention adopts the following technical scheme that
A kind of disposable microneedle devices, it includes base, microneedle component, lid and some connections being dissolvable in water ethanol
Bar；
This microneedle component includes pedestal and the micropin some spaced apart being located on pedestal；The roof of this pedestal and this end
Respectively offer, on the diapire of seat, the conical socket that quantity is identical with connecting rod；The two the most tapered shapes of end of each connecting rod, each
A wherein end of connecting rod is flush-mounted in correspondence one conical socket of the diapire of this base, and another end of each connecting rod is embedding
In correspondence one conical socket of the roof being loaded on this pedestal；Some connecting rods are spaced formation one Triangular array；
This lid is removably fastened on this base, forms a confined space between this lid and this base, this micropin
Assembly and connecting rod are positioned at this confined space.
Further, this microneedle component also includes some chance water and the variable color part of variable color, the quantity of variable color part and micropin
Quantity is identical, and variable color part and micropin one_to_one corresponding；Some micropins form a crisscross microneedle array；Each variable color part is solid
On pedestal, and outside the upper end of the micropin being sheathed on correspondence.
Further, the tapered shape of each micropin；Each hemispherical shape of variable color part, offers in the middle part of it and runs through sphere and the end
The conical through-hole in face, outside the upper end of the micropin that each variable color part is sheathed on correspondence by this conical through-hole.
Further, this variable color part is variable color silica gel part.
Further, offering a liquid storage cylinder in this base, the diapire of this base offers the liquid outlet of this liquid storage cylinder of connection,
Offering a horizontal liquid-conveying ducts in this pedestal, the sidewall of this pedestal offers the inlet of this horizontal liquid-conveying ducts of a connection, this end
The liquid outlet of seat connects the inlet of this pedestal by a catheter；This horizontal liquid-conveying ducts of a connection is offered in each micropin
Liquid-conveying ducts.
Further, the terminal surface of each micropin is one domatic.
Further, this connecting rod is the connecting rod being made up of thermoplastic phenolic resin.
Further, this pedestal and micropin are made by metal or monocrystal silicon are one-body molded.
Beneficial effects of the present invention is as follows:
1, the connecting rod of the present invention constitutes the supporting construction of a firm Triangular array, can make this microneedle component jail
It is fixed on this base by ground.When user is want to use this device by sterilization secondary, and this disposable microneedle devices is soaked
When ethanol, owing to some connecting rods are spaced, each connecting rod fully and Ethanol Exposure, can accelerate the dissolving of connecting rod,
The connecting rod at three angles being distributed in this Triangular array is quickly dissolved, thus can quickly destroy this supporting construction so that
This microneedle component comes off from this base, effectively prevents again with this microneedle devices, fundamentally avoids cross infection, relatively
The array of other shapes, this Triangular array can have firm support and rapidly-soluble effect concurrently.
2, user can be by observing the color of variable color part intuitively, to judge whether this device is to use first.
3, the percutaneous aperture of relatively conventional medicinal liquid enters skin surface, and this device directly passes through liquid-conveying ducts by medicine
Liquid imports skin surface, not only improves operational efficiency, and avoids medicinal liquid by outside contamination, can be introduced directly into by pollution-free medicinal liquid
Skin, rapid hygiene.
Accompanying drawing explanation
Fig. 1 is the local longitudinal profile schematic diagram of the better embodiment of the disposable microneedle devices of the present invention；
Fig. 2 is the horizontal section schematic diagram of the disposable microneedle devices of Fig. 1；
Fig. 3 is the fragmentary bottom schematic diagram of the microneedle component of the disposable microneedle devices of Fig. 1.
Detailed description of the invention
Below in conjunction with accompanying drawing and detailed description of the invention, the present invention is described further:
Refer to Fig. 1 to Fig. 3, the present invention relates to a kind of disposable microneedle devices, its better embodiment include base 10,
Microneedle component 40, lid 20 and some connecting rods 30 being dissolvable in water ethanol.
This microneedle component 40 includes pedestal 41 and the micropin 43 some spaced apart being located on pedestal 41.Some micropins 43
One-body molded with pedestal 41.The roof of this pedestal 41 respectively offers, with on the diapire of this base 10, the cone that quantity is identical with connecting rod 30
Connected in star.The two the most tapered shapes of end of each connecting rod 30, a wherein end of each connecting rod 30 is flush-mounted in this base 10
Diapire correspondence one conical socket in, another end of each connecting rod 30 is flush-mounted in correspondence one cone of the roof of this pedestal 41
In connected in star.Some connecting rods 30 are spaced formation one Triangular array.
So, this Triangular array constitutes a firm supporting construction, and this microneedle component 40 can be made to fix securely
On this base 10.After the most disposable microneedle devices used once, user is want to be used by sterilization secondary, and by originally one
When secondary property microneedle devices is soaked in ethanol, owing to some connecting rods 30 are spaced, each connecting rod 30 can fully connect with ethanol
Touching, accelerate the dissolving of connecting rod 30, the connecting rod 30 at three angles being distributed in this Triangular array is quickly dissolved, thus can
Quickly destroy this supporting construction so that this microneedle component 40 comes off from this base 10, effectively prevents from filling again with this micropin
Putting, fundamentally avoid the array of cross infection, relatively other shapes, this Triangular array can have firm support concurrently with quick
The effect dissolved.
This connecting rod 30 can use any the most all kinds of phenolic resin of solid fraction component that can be dissolved in ethanol in prior art, excellent
Selection of land, can use thermoplastic phenolic resin, the most exhaustive at this.
This lid 20 is removably fastened on this base 10, forms a confined air between this lid 20 and this base 10
Between, this microneedle component 40 and connecting rod 30 are respectively positioned in this confined space, thus can ensure microneedle component 40 avoid by steam and
Dust is polluted.
This microneedle component 40 also includes some chance water and the variable color part 42 of variable color, the number of the quantity of variable color part 42 and micropin 43
Measure identical, and variable color part 42 and micropin 43 one_to_one corresponding.Some micropins 43 form a crisscross microneedle array.Each variable color
Part 42 is fixed on pedestal 41, and outside the upper end of the micropin 43 being sheathed on correspondence.
Each tapered shape of micropin 43.Each hemispherical shape of variable color part 42, it is possible to increase variable color part 42 contacts with moisture
Area, increases variable color efficiency, offers the conical through-hole running through sphere and bottom surface in the middle part of it, and each variable color part 42 is led to by this taper
Outside the upper end of the micropin 43 that borehole jack is located at correspondence.
Off-color material and metachromatic principle that this variable color part 42 is used be would know that by prior art, as this variable color part 42 can be
Variable color silica gel part, the most exhaustive at this.Before using, the microneedle component 40 of this device is contained in confined space, thus will
Variable color part 42 and moisture or ethanol isolation, it is ensured that variable color part 42 keeps primary colors, thus, after user can determine opening intuitively
Microneedle devices is to use first.When micropin 43 injects skin, variable color part 42 is close to skin, and the sweat of skin surface contains water
Point, variable color silica gel part absorbs moisture and becomes red from blueness, and so, user can confirm this micropin intuitively by variable color part 42
Device used, thus was not repeated to use.Furthermore, this variable color part 42 also acts as position-limiting action, can make microneedle component 40
More fit with skin and contact.It addition, when microneedle devices is soaked in ethanol by user, owing to ethanol comprising moisture, should
Variable color part 42 also can variable color.
Offering a liquid storage cylinder 412 in this base 10, what the diapire of this base 10 offered this liquid storage cylinder 412 of a connection goes out liquid
Mouthful.Offering a horizontal liquid-conveying ducts in this pedestal 41, the sidewall of this pedestal 41 offers the feed liquor of this horizontal liquid-conveying ducts of a connection
Mouthful, the liquid outlet of this base 10 connects the inlet of this pedestal 41 by a catheter 413, offers one even in each micropin 43
The liquid-conveying ducts 431 of this horizontal liquid-conveying ducts logical.So, medicinal liquid can be imported in this liquid storage cylinder 412 by user in advance, then by micro-
Pin 43 injects skin, and the medicinal liquid of liquid storage cylinder 412 will flow into the horizontal liquid-conveying ducts of this pedestal 41 via catheter 431, and by
This horizontal liquid-conveying ducts is delivered to each liquid-conveying ducts 431, and to flow into skin surface, relatively conventional medicinal liquid is percutaneous little
Hole enters skin surface, and medicinal liquid is directly imported skin surface by liquid-conveying ducts 431 by this device, not only improves operational efficiency,
And avoid medicinal liquid to be polluted by the impurity of air, pollution-free medicinal liquid can be introduced directly into skin, rapid hygiene.
The terminal surface of each micropin 43 is one domatic, so, micropin 43 can be made sharper and be not easily broken.
This pedestal 41 and micropin 43 are made by metal or monocrystal silicon are one-body molded, thus micropin 43 can be made to be not easily broken.
For a person skilled in the art, can technical scheme as described above and design, make other each
Plant corresponding change and deformation, and all these changes and deforms the protection model that all should belong to the claims in the present invention
Within enclosing.
Claims (8)
1. a disposable microneedle devices, it is characterised in that: it includes base, microneedle component, lid and some is dissolvable in water wine
The connecting rod of essence；
This microneedle component includes pedestal and the micropin some spaced apart being located on pedestal；The roof of this pedestal and this base
The conical socket that quantity is identical with connecting rod is respectively offered on diapire；The two the most tapered shapes of end of each connecting rod, each connection
A wherein end of bar is flush-mounted in correspondence one conical socket of the diapire of this base, and another end of each connecting rod is flush-mounted in
In correspondence one conical socket of the roof of this pedestal；Some connecting rods are spaced formation one Triangular array；
This lid is removably fastened on this base, forms a confined space between this lid and this base, this microneedle component
It is positioned at this confined space with connecting rod.
2. disposable microneedle devices as claimed in claim 1, it is characterised in that: this microneedle component also includes that some chance water becomes
The variable color part of color, the quantity of variable color part is identical with the quantity of micropin, and variable color part and micropin one_to_one corresponding；Some micropins form one
Crisscross microneedle array；Each variable color part is fixed on pedestal, and outside the upper end of the micropin being sheathed on correspondence.
3. disposable microneedle devices as claimed in claim 2, it is characterised in that: the tapered shape of each micropin；Each variable color part
Hemispherical shape, offers the conical through-hole running through sphere and bottom surface in the middle part of it, each variable color part is sheathed on by this conical through-hole
Outside the upper end of a corresponding micropin.
4. disposable microneedle devices as claimed in claim 2, it is characterised in that: this variable color part is variable color silica gel part.
5. disposable microneedle devices as claimed in claim 1, it is characterised in that: offer a liquid storage cylinder in this base, this base
Diapire offer the liquid outlet of this liquid storage cylinder of connection, offer a horizontal liquid-conveying ducts in this pedestal, the sidewall of this pedestal is offered
One inlet connecting this horizontal liquid-conveying ducts, the liquid outlet of this base connects the inlet of this pedestal by a catheter；
The liquid-conveying ducts of this horizontal liquid-conveying ducts of a connection is offered in each micropin.
6. microneedle devices as claimed in claim 5 disposable, it is characterised in that: the terminal surface of each micropin is one domatic.
7. disposable microneedle devices as claimed in claim 1, it is characterised in that: this connecting rod is by thermoplastic phenolic resin system
The connecting rod become.
8. disposable microneedle devices as claimed in claim 1, it is characterised in that: this pedestal and micropin are by metal or monocrystal silicon one
Body formed make.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410296973.4A CN104043192B (en) | 2014-06-28 | 2014-06-28 | Disposable microneedle devices |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410296973.4A CN104043192B (en) | 2014-06-28 | 2014-06-28 | Disposable microneedle devices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104043192A CN104043192A (en) | 2014-09-17 |
| CN104043192B true CN104043192B (en) | 2016-08-24 |
Family
ID=51496898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410296973.4A Active CN104043192B (en) | 2014-06-28 | 2014-06-28 | Disposable microneedle devices |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104043192B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3054137B1 (en) * | 2016-07-21 | 2021-08-27 | Univ Angers | LOCOREGIONAL INJECTION IMPLANTABLE MEDICAL DEVICE |
| CN106726547A (en) * | 2016-08-31 | 2017-05-31 | 吴月丽 | Acupuncture needle show |
| DE102017118419A1 (en) * | 2017-08-11 | 2019-02-14 | Lts Lohmann Therapie-Systeme Ag | Microneedle array having a color change indicator |
| CN211410676U (en) * | 2019-08-23 | 2020-09-04 | 苏州纳生微电子有限公司 | Quantitative liquid supply device |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
| CN202314939U (en) * | 2010-11-10 | 2012-07-11 | 吉林大学 | Easy painless medicine infusing device |
| CN102327656B (en) * | 2011-10-18 | 2013-05-08 | 清华大学 | Disposable array miniature injection needle head |
| CN204073087U (en) * | 2014-06-28 | 2015-01-07 | 陈彦彪 | Disposable microneedle devices |
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2014
- 2014-06-28 CN CN201410296973.4A patent/CN104043192B/en active Active
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| Publication number | Publication date |
|---|---|
| CN104043192A (en) | 2014-09-17 |
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Effective date of registration: 20161128 Address after: Panyu District of Guangzhou City, Guangdong province 510000 Xiaoguwei Street Outer Ring Road No. 280 Building No. 225, a department of Guangdong Pharmaceutical University Patentee after: Guangzhou gunnery Biotechnology Co. Ltd. Address before: 522000 Guangdong province Jieyang City Airport district town Room Seven Tu Wei village in Xinxiang Patentee before: Chen Yanbiao |