CN103110789B

CN103110789B - Traditional Chinese medicine composition for treating infantile enuresis

Info

Publication number: CN103110789B
Application number: CN201310048158.1A
Authority: CN
Inventors: 刘照民
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-01-24
Filing date: 2013-01-24
Publication date: 2014-03-12
Anticipated expiration: 2033-01-24
Also published as: CN103110789A

Abstract

The invention discloses a traditional Chinese medicine composition for treating infantile enuresis. In the traditional Chinese medicine, the infantile enuresis is categorized as insufficiency of natural endowmen and caused by deficiency-caused cold, deficiency of spleen qi, disorder of water lane, excessive vesica urinaria restriction and urinary bladder opening-closing disorder. In order to solve the problems, the traditional Chinese medicines, which have the effects of strengthening the spleen and replenishing qi, tonifying and reinforcing the kidney and tranquilizing by nourishing the heart, are selected to be decocted with water to obtain decoction, wherein the medicines are as follows: spleenwort, human placentae, white atractylodes rhizome, American ginseng, semen biotae shelled, poria with hostwood, semen alli tuberose, gordon euryale seed, mantis egg-case, divaricate knotweed root, common fennel, faenum graecum and Chinese yam. According to the clinical test of preparation department, the total effective rate is 96.0% which is remarkably better than that of the control group. In particular, the treatment by Chinese herbs is not only good in treatment effect, but also stable in effect and free of recurrence after the treatment.

Description

A kind of Chinese medicine composition for the treatment of infantile enuresis

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of infantile enuresis.

Background technology

Child bedwetting is a general phenomenon, and 3 years old following children's is even in fact that to wet the bed be normal physiological phenomenon, and the head of a family is anxiety too.。If but the above child in 5 years old or 5 years old repeatedly fall asleep after unconscious urinating, reach weekly 2 times above and continue at least 6 months, and waking state is next without this phenomenon, should be regarded as extremely, being referred to as clinically or infantile enuresis.As found, child obtained infantile enuresis, and Seek early medical advice diagnosis and treatment, in order to avoid affect child's physical and mental health, brought inconvenience and the burden of life to the head of a family.Applicant's clinical trial for many years proves, this disease of Chinese medicine has obvious advantage, and evident in efficacy.

Summary of the invention

The object of the invention is to provide a kind of Chinese medicine composition for the treatment of infantile enuresis.Chinese medicine thinks that bed-wetting belongs to natural endowment deficiency, below element deficiency and cold, takes deficiency of spleen-QI, and water channel is uncomfortable, and bladder constraint is immoderate, open due to entire mistake department.The traditional Chinese medical science is in treatment, and invigorating the spleen and benefiting QI, reinforce of kidney, tranquilizing by nourishing the heart are the rule for the treatment of.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine composition of this treatment infantile enuresis is made by the Chinese medicine of following weight portion: Asplenium trchomanes L. 15-25 part, Placenta Hominis 4-6 part, Rhizoma Atractylodis Macrocephalae 7-11 part, Radix Panacis Quinquefolii 1.5-2.5g, Semen Platycladi 9-12 part, Poria cum Radix Pini 5-7 part, Semen Allii Tuberosi 1-3 part, Semen Euryales 10-12 part, Ootheca Mantidis 13-17 part, Radix polygoni divaricati 3-5 part, Fructus Foeniculi 6-9 part, Semen Trigonellae 2-4 part, Rhizoma Dioscoreae 15-25 part on stone.

Preferably, 22 parts of Asplenium trchomanes L., 5 parts of Placenta Hominiss, 10 parts of the Rhizoma Atractylodis Macrocephalaes, Radix Panacis Quinquefolii 2g, 11 parts of Semen Platycladi, 6 parts of Poria cum Radix Pinis, 2 parts of Semen Allii Tuberosi, 11 parts of Semen Euryaless, 15 parts of Ootheca Mantidiss, 4 parts of Radix polygoni divaricaties, 8 parts of Fructus Foeniculi, 3 parts of Semen Trigonellae, 20 parts of Rhizoma Dioscoreaes on stone.

Preparation method is made decoction by traditional method decocting.

In side: Asplenium trchomanes L. clearing heat and moistening lung on stone, diuresis promoting, subduing swelling and detoxicating; Placenta Hominis, Semen Euryales the kidney warming are mended essence, benefiting QI and nourishing blood, invigorating the spleen to arrest diarrhea; The Rhizoma Atractylodis Macrocephalae, Radix Panacis Quinquefolii air making-up and spleen enlivening, YIN nourishing and the production of body fluid promoting, dampness diuretic; Semen Platycladi, Poria cum Radix Pini's tranquilizing by nourishing the heart, moisten just unimpeded; Semen Allii Tuberosi, Ootheca Mantidis liver and kidney tonifying, controlling nocturnal emission with astringent drugs reducing urination; Radix polygoni divaricati, Semen Trigonellae dispelling colds and warming kidney.The Fructus Foeniculi cold expelling of regulating the flow of vital energy, has supporing yang road; Rhizoma Dioscoreae strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney essence.

Clinical data

1, this group of physical data case is the court's urinary system special outpatient clinic infant, chooses 100 examples, is divided at random treatment group and matched group, treatment group 50 examples, male 28 examples, female's 22 examples; 5～14 years old age, 5～8 years old 23 example wherein, 9～14 years old 27 example; The course of disease 0.5～10 year, regular person's 28 examples of the enuresis, irregular person's 22 examples; In family, have hereditary medical history 15 examples, 17 customary waist sacral x-rays are taken the photograph sheet, and 8 examples have waist, sacral spina bifida occulta, and 10 examples are normal; Matched group 50 examples, male 26 examples of example, female's 24 examples; 4～9 years old 26 example wherein, 9～15 years old 24 example; The course of disease 1～9 year, regular person's 27 examples of the enuresis, irregular person's 23 examples; In family, have hereditary medical history 14 examples, 18 customary waist sacral x-rays are taken the photograph sheet, and 7 examples have waist, sacral spina bifida occulta, and 11 examples are normal; Above two groups of experimental checks, all case routine urinalysis, B ultrasonic etc. check all normal; Two groups of infants all have comparability (P > 0.05) at aspects such as age, sex, the course of disease and experimental check, B ultrasonic situations.There is comparability.

2, in the < < traditional Chinese medical science disease Standardization of diagnosis and curative effect > > that diagnostic criteria is promulgated with reference to State Administration of Traditional Chinese Medicine, relevant criterion is drafted.

3, Therapeutic Method treatment group infant is taken Chinese medicine composition of the present invention, get Asplenium trchomanes L. 22g on stone, Placenta Hominis 5g, Rhizoma Atractylodis Macrocephalae 10g, Radix Panacis Quinquefolii 2g, Semen Platycladi 11g, Poria cum Radix Pini 6g, Semen Allii Tuberosi 2g, Semen Euryales 11g, Ootheca Mantidis 15g, Radix polygoni divaricati 4g, Fructus Foeniculi 8g, Semen Trigonellae 3g, Rhizoma Dioscoreae 20g, decocting is made decoction.Every day, potion, divided morning, late 2 decoction being taken warmly; Matched group adopts imipramine hydrochloride (Shanghai Sunve Pharmaceutical Co., Ltd., specification: 25mg/ sheet, lot number: 20070105) oral, predose is 12.5mg/d, and before sleeping, 1h is oral; After one week, increase to 25mg/d, within 10 years old, above infant can be used to 37.5mg/d.Two groups equal 15 days is a course for the treatment of.

4, criterion of therapeutical effect is fully recovered with reference to the Standardization of diagnosis and curative effect > > (1) that cures the desease in < <: without enuresis phenomenon, occur, after sleep, urine is anticipated and can be urinated from waking up; (2) effective: enuresis phenomenon obviously reduces, and meets inducement and occasionally can occur; (3) invalid: enuresis phenomenon is without being clearly better.

5, curative effect comparison after two courses for the treatment of of two groups of therapeutic outcomes treatment, treatment group 50 examples, wherein fully recover 38 (76.0%), effective 10 (20.0%), invalid 2 (4.0%), and total effective rate is 96.0%; Matched group 50 examples, wherein fully recover 18 (36.0%), effective 23 (46.0%), no effect 9 (18.0%), and total effective rate is 82.0%; Treatment group cure rate, total effective rate, be obviously better than matched group, and two groups of comparisons have significant (P < 0.05).

The infant for the treatment of group recovery from illness, follows up a case by regular visits to half a year without recurrence; The infant of matched group recovery from illness, follows up a case by regular visits to 9 recurrences half a year.

6, model case Liu, female, 8 years old, first visit on July 6 in 2008.Wet the bed since the childhood, 3～4 times every night, spiritlessness and weakness, absent minded, moving perspiration, pale white complexion is simple and unadorned, stomach poor appetite, body is partially thin, coldness of the body with chills, clear urine in large amounts, defecates shapeless, x-ray inspection shows: young hidden the splitting of sacrum, be diagnosed as the enuresis, and card belongs to asthenia of both the spleen and kidney, disturbance in functioning of QI, water channel is failed to keep an appointment; In treatment, with spleen reinforcing the kidney warming, astringency inducing is only lost, and takes above-described Chinese medicine composition, every day potion, every day, each once, was taken medicine after two weeks sooner or later, the enuresis obviously reduces, the food of receiving is normal, continues to take two courses for the treatment of, enuresis recovery from illness, follows up a case by regular visits to half a year without recurrence.

The specific embodiment

Embodiment mono-: take Asplenium trchomanes L. 22g on stone, Placenta Hominis 5g, Rhizoma Atractylodis Macrocephalae 10g, Radix Panacis Quinquefolii 2g, Semen Platycladi 11g, Poria cum Radix Pini 6g, Semen Allii Tuberosi 2g, Semen Euryales 11g, Ootheca Mantidis 15g, Radix polygoni divaricati 4g, Fructus Foeniculi 8g, Semen Trigonellae 3g, Rhizoma Dioscoreae 20g.By traditional method decocting, make decoction.

Embodiment bis-: take Asplenium trchomanes L. 15g on stone, Placenta Hominis 4g, Rhizoma Atractylodis Macrocephalae 7g, Radix Panacis Quinquefolii 1.5g, Semen Platycladi 9g, Poria cum Radix Pini 5g, Semen Allii Tuberosi 1.5g, Semen Euryales 10g, Ootheca Mantidis 13g, Radix polygoni divaricati 4g, Fructus Foeniculi 6g, Semen Trigonellae 2g, Rhizoma Dioscoreae 15g.By traditional method decocting, make decoction

Embodiment tri-: take Asplenium trchomanes L. 25g on stone, Placenta Hominis 6g, Rhizoma Atractylodis Macrocephalae 11g, Radix Panacis Quinquefolii 2.5g, Semen Platycladi 12g, Poria cum Radix Pini 7g, Semen Allii Tuberosi 3g, Semen Euryales 12g, Ootheca Mantidis 17g, Radix polygoni divaricati 5g, Fructus Foeniculi 9g, Semen Trigonellae 5g, Rhizoma Dioscoreae 18g.By traditional method decocting, make decoction.

Claims

1. treat a Chinese medicine composition for infantile enuresis, it is characterized in that this Chinese medicine composition made by the Chinese medicine of following weight portion: Asplenium trchomanes L. 15-25 part, Placenta Hominis 4-6 part, Rhizoma Atractylodis Macrocephalae 7-11 part, Radix Panacis Quinquefolii 1.5-2.5g, Semen Platycladi 9-12 part, Poria cum Radix Pini 5-7 part, Semen Allii Tuberosi 1-3 part, Semen Euryales 10-12 part, Ootheca Mantidis 13-17 part, Radix polygoni divaricati 3-5 part, Fructus Foeniculi 6-9 part, Semen Trigonellae 2-4 part, Rhizoma Dioscoreae 15-25 part on stone.

2. a kind of Chinese medicine composition for the treatment of infantile enuresis according to claim 1, is characterized in that this Chinese medicine composition made by the Chinese medicine of following weight portion: 22 parts of Asplenium trchomanes L., 5 parts of Placenta Hominiss, 10 parts of the Rhizoma Atractylodis Macrocephalaes, Radix Panacis Quinquefolii 2g, 11 parts of Semen Platycladi, 6 parts of Poria cum Radix Pinis, 2 parts of Semen Allii Tuberosi, 11 parts of Semen Euryaless, 15 parts of Ootheca Mantidiss, 4 parts of Radix polygoni divaricaties, 8 parts of Fructus Foeniculi, 3 parts of Semen Trigonellae, 20 parts of Rhizoma Dioscoreaes on stone.