CN103099915A

CN103099915A - Traditional Chinese medicine enema for treating endometriosis

Info

Publication number: CN103099915A
Application number: CN2013100613716A
Authority: CN
Inventors: 韩晓燕
Original assignee: 韩晓燕
Current assignee: HAIMEN HUANGHAI PIONEER PARK SERVICES CO., LTD.
Priority date: 2013-02-17
Filing date: 2013-02-17
Publication date: 2013-05-15
Anticipated expiration: 2033-02-17
Also published as: CN103099915B

Abstract

The invention discloses a traditional Chinese medicine enema for treating endometriosis. Endometriosis belongs to the domain of ''dysmenorrhea'' ''abdominal mass'' and ''infertility'' in traditional Chinese medicine; and traditional Chinese medicine believes that blood stasis is the basic cause of endometriosis. Therefore, the traditional Chinese medicine enema provided by the invention is prepared from Securidaca inappendiculata, Pinellia cordata, Stellaria media, Haloragis micrantha, kadsura pepper stem, gynura segetum, all-grass of himalayan Horsegentian, fiveleaf akebia fruit, Henry Clematis Root, root of three-nerved spicebush, human placenta, placenta, radix scrophulariae and cinnamon. According to clinical trials, the enema has a total effective rate reaching 95.3%, and indicators including treatment time, adverse reaction rate, tolerance and patient satisfaction rate better than a control group; therefore, the enema is worthy of clinical application.

Description

A kind of Chinese medicinal enema for the treatment of endometriosis

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicinal enema for the treatment of metrecotpia disease.

Background technology

Endometriosis refers to that patient's endometrium grows into beyond uterine cavity, and infiltrate, the pathological changes such as growth and cyclic hemorrhage, cause the patient affecting conditions of the symptoms such as pain, tuberosity enclosed mass to occur.The commonly encountered diseases of gynecological clinic, frequently-occurring disease.In recent years, this sick sickness rate is in rising trend, and China women of child-bearing age's sickness rate is in 15% left and right.Common sympton has lumbosacral region pain, dysmenorrhea, non-menstrual phase pain, proctalgia, sexual anhedonia, lower abdominal pain etc. to have a strong impact on Quality of Life, untimelyly will cause chronic pelvic pain, the disease such as infertile if treat.The common method of current clinical treatment has pseudo pregnancy therapy, pseudo menopause therapy, ectopic focus is disappeared, but relapse rate and untoward reaction rate is higher; Operative therapy is expensive because of medical expense, and wound is large, is difficult to the patient and is accepted.And even using herbal enema that endometriosis is treated is present later development trend.

Summary of the invention

The purpose of this invention is to provide a kind of Chinese medicinal enema for the treatment of endometriosis.Endometriosis belongs to the categories such as motherland's medical science " dysmenorrhea " " lump in the abdomen " " infertile ", and Chinese medicine thinks that blood stasis is the Basic disease cause of endometriosis.

The objective of the invention is to be achieved through the following technical solutions, the Chinese medicinal enema of this treatment endometriosis is made by the Chinese medicine of following weight portion: Radix securidacae 25-30 part, Rhizoma pinelliae cordatae 5-15 part, Herba malachii aquatici 10-15 part, Herba Haloragidis Micranthae 5-7 part, Caulis Piperis Kadsurae 9-13 part, Radix Polygoni hispidi 20-25 part, Radix Triostei Pinnatifidi 6-8 part, Fructus Akebiae 10-20 part, Radix Clematidis Henryi 13-18 part, Radix Linderae 10-15 part, Placenta Hominis 15-20 part, Radix Scrophulariae 8-12 part, Cortex Cinnamomi 7-9 part.

Preferably, 28 parts of Radix securidacae, 10 parts of Rhizoma pinelliae cordatae, 13 parts of Herba malachii aquaticis, 6 parts of Herba Haloragidis Micranthae, 11 parts of Caulis Piperis Kadsuraes, 22 parts of Radix Polygoni hispidis, 7 parts of Radix Triostei Pinnatifidis, 15 parts of Fructus Akebiaes, 15 parts of Radix Clematidis Henryi, 12 parts of the Radixs Linderae, 18 parts of Placenta Hominiss, 10 parts of Radix Scrophulariaes, 8 parts of Cortex Cinnamomis.

Preparation method adds water 500mL with above-mentioned Chinese medicine, and slow fire boiling is fried in shallow oil to 150mL, and the filtering residue extracting juice is standby.

In the side: Radix securidacae, Rhizoma pinelliae cordatae, Herba malachii aquatici, Herba Haloragidis Micranthae blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, heat-clearing and toxic substances removing; Caulis Piperis Kadsurae, Radix Polygoni hispidi, Radix Triostei Pinnatifidi expelling wind and removing dampness, dredge the meridian passage; Fructus Akebiae, Radix Clematidis Henryi depressed liver-energy dispersing and QI regulating, anti-inflammation; Radix Linderae promoting the circulation of QI to relieve pain, warming kidney for dispelling cold; The Placenta Hominis the kidney warming is mended essence, benefiting QI and nourishing blood; The Radix Scrophulariae clearing away heat and cooling blood, the YIN nourishing detoxifcation; It is supporing yang that Cortex Cinnamomi is mended fire, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian.

Clinical data

1, the selected case of physical data totally 166 examples, be my Out-patient Department patient, meets the Diagnosis of Endometriosis standard, shows as lower abdominal pain, dysmenorrhea, sexual intercourse discomfort etc. more.Inspection lay one's hand on and pelvic cavity in have that tenderness tuberosity or palace are other inactive capsule enclosed mass.Imaging examination can be determined ovarian endometrial cyst.Be divided at random treatment group 86 example and matched group 80 examples.21～45 years old treatment group age, average 34.7 years old; The course of disease 0.5～11.0 year, average 4.5 years; Dysmenorrhea 62 examples, sexual anhedonia 38 examples, rectal tenesmus sense 60 examples, menoxenia 36 examples, infertility 12 examples, ovarian cyst 42 examples, multiple 16 examples after the chocolate cyst excision merge myometrial gland tumor 20 examples; 22～48 years old matched group age, average 35 years old; The course of disease 0.7～13.0 year, average 5.0 years; Dysmenorrhea 58 examples, sexual anhedonia 42 examples, rectal tenesmus sense 64 examples, menoxenia 32 examples, infertility 10 examples, ultrasonography for 38 cases of ovarian cysts, multiple 12 examples after the chocolate cyst excision merge myometrial gland tumor 22 examples.Two groups of ages, the course of disease, clinical symptoms, sign is there was no significant difference (P＞0.05) relatively, has comparability.

2, the diagnostic criteria diagnosis meets " the endometriosis combination of Chinese and Western medicine diagnosis and treatment standard " of nineteen ninety CAIM (Chinese Association Of Integrative Medicine) department of obstetrics and gynecology Professional Committee the 3rd academic conference revision.1. gradual abdominal pain in menstruation.2. menstrual period lower abdomen and the aggravation of carrying out property of lumbosacral region discomfort.3. posterior fornix and jarjavay's ligaments tuberosity.4. attachment area has enclosed mass.5. menstruation front and back enclosed mass has the variation of obvious size.One of 5. 3. 2. 1. all one of have and 4. both coexist and can make a definite diagnosis.

3, the Therapeutic Method treatment group is used above-described Chinese medicinal enema, namely get Radix securidacae 28g, Rhizoma pinelliae cordatae 10g, Herba malachii aquatici 13g, Herba Haloragidis Micranthae 6g, Caulis Piperis Kadsurae 11g, Radix Polygoni hispidi 22g, Radix Triostei Pinnatifidi 7g, Fructus Akebiae 15g, Radix Clematidis Henryi 15g, Radix Linderae 12g, Placenta Hominis 18g, Radix Scrophulariae 10g, Cortex Cinnamomi 8g, above-mentioned Chinese medicine is added water 500mL, slow fire boiling, fry in shallow oil to 150mL, the filtering residue extracting juice, approximately be filled into patient's internal rectum 35 ℃ the time until enema, more than staying medicine 30min, according to patient's tolerance degree time expand, time is longer, and curative effect is better; 1 times/day, 20 is 1 course for the treatment of, and the patient stops treatment menstrual period, is used in conjunction 2～5 courses for the treatment of according to conditions of patients and recovery extent.The oral tamoxifen tablet of matched group (Finland, Kou Er storehouse, the limited production of the new chemical industry of German moral); In menstruation beginning in the 5th day, each 10mg serve on 20 days every day 2 times, and two groups are 20 is 1 course for the treatment of.

4, criterion of therapeutical effect is with reference to the efficacy assessment standard of " new Chinese medicine guideline of clinical investigations " dysmenorrhea.Recovery from illness: take medicine rear abdominal pain in menstruation and other transference cure, integration is 0, continuous 3 menstrual cycle have no recurrence; Produce effects: below 1/2 of integration before the rear integration for the treatment of is down to and is treated, stomachache obviously alleviates, and other symptom takes a turn for the better, and the disobedience analgesic can be adhered to work; Effectively: after treatment, integration is down to 1/2～3/4 of the front integration for the treatment of, and stomachache alleviates, and all the other symptoms take a turn for the better, and take analgesic and can adhere to work; Invalid: stomachache and symptom are without improvement.

5, (1) two group of patient treatment of therapeutic outcome after 3 courses for the treatment of curative effect relatively see Table 1.

Table 1 liang group patient clinical curative effect relatively

The treatment group total effective rate is 95.3%; The matched group total effective rate is 81.3%; Two groups are compared cure rate, and the total effective rate treatment group obviously is better than matched group, and difference has significant (P＜0.05)

(2) two groups of patient clinical data relatively see Table 2.

Table 2 liang group patient clinical data relatively

It is slight uncomfortable that treatment group patient only has 3 examples to occur, and the untoward reaction rate is 3.5%, and the matched group patient has 12 examples to occur feeling sick, and the symptoms such as vomiting, bad reflection ratio are 15.0%; In the course for the treatment of, the relatively middle treatment group of the clinical datas such as tolerance degree and patient satisfaction rate all has significant advantage, and Epidemiological Analysis, have significant statistical significance P＜0.05 by statistics.

The specific embodiment

Embodiment one: take Radix securidacae 28g, Rhizoma pinelliae cordatae 10g, Herba malachii aquatici 13g, Herba Haloragidis Micranthae 6g, Caulis Piperis Kadsurae 11g, Radix Polygoni hispidi 22g, Radix Triostei Pinnatifidi 7g, Fructus Akebiae 15g, Radix Clematidis Henryi 15g, Radix Linderae 12g, Placenta Hominis 18g, Radix Scrophulariae 10g, Cortex Cinnamomi 8g.Above-mentioned Chinese medicine is added water 500mL, and slow fire boiling is fried in shallow oil to 150mL, and the filtering residue extracting juice is standby.

Embodiment two: take Radix securidacae 25g, Rhizoma pinelliae cordatae 5g, Herba malachii aquatici 15g, Herba Haloragidis Micranthae 7g, Caulis Piperis Kadsurae 13g, Radix Polygoni hispidi 20g, Radix Triostei Pinnatifidi 6g, Fructus Akebiae 10g, Radix Clematidis Henryi 18g, Radix Linderae 10g, Placenta Hominis 15g, Radix Scrophulariae 8g, Cortex Cinnamomi 7g.Above-mentioned Chinese medicine is added water 500mL, and slow fire boiling is fried in shallow oil to 150mL, and the filtering residue extracting juice is standby.

Embodiment three: take Radix securidacae 30g, Rhizoma pinelliae cordatae 15g, Herba malachii aquatici 10g, Herba Haloragidis Micranthae 5g, Caulis Piperis Kadsurae 9g, Radix Polygoni hispidi 25g, Radix Triostei Pinnatifidi 8g, Fructus Akebiae 20g, Radix Clematidis Henryi 13g, Radix Linderae 15g, Placenta Hominis 20g, Radix Scrophulariae 12g, Cortex Cinnamomi 9g.Above-mentioned Chinese medicine is added water 500mL, and slow fire boiling is fried in shallow oil to 150mL, and the filtering residue extracting juice is standby.

Claims

1. Chinese medicinal enema for the treatment of endometriosis is characterized in that this Chinese medicinal enema made by the Chinese medicine of following weight portion: Radix securidacae 25-30 part, Rhizoma pinelliae cordatae 5-15 part, Herba malachii aquatici 10-15 part, Herba Haloragidis Micranthae 5-7 part, Caulis Piperis Kadsurae 9-13 part, Radix Polygoni hispidi 20-25 part, Radix Triostei Pinnatifidi 6-8 part, Fructus Akebiae 10-20 part, Radix Clematidis Henryi 13-18 part, Radix Linderae 10-15 part, Placenta Hominis 15-20 part, Radix Scrophulariae 8-12 part, Cortex Cinnamomi 7-9 part.

2. a kind of Chinese medicinal enema for the treatment of endometriosis according to claim 1 is characterized in that this Chinese medicinal enema made by the Chinese medicine of following weight portion: 28 parts of Radix securidacae, 10 parts of Rhizoma pinelliae cordatae, 13 parts of Herba malachii aquaticis, 6 parts of Herba Haloragidis Micranthae, 11 parts of Caulis Piperis Kadsuraes, 22 parts of Radix Polygoni hispidis, 7 parts of Radix Triostei Pinnatifidis, 15 parts of Fructus Akebiaes, 15 parts of Radix Clematidis Henryi, 12 parts of the Radixs Linderae, 18 parts of Placenta Hominiss, 10 parts of Radix Scrophulariaes, 8 parts of Cortex Cinnamomis.