CN103097894A - 通过散射对致动的簇的探测 - Google Patents

通过散射对致动的簇的探测 Download PDF

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Publication number
CN103097894A
CN103097894A CN2011800327535A CN201180032753A CN103097894A CN 103097894 A CN103097894 A CN 103097894A CN 2011800327535 A CN2011800327535 A CN 2011800327535A CN 201180032753 A CN201180032753 A CN 201180032753A CN 103097894 A CN103097894 A CN 103097894A
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CN
China
Prior art keywords
frequency
particles
clusters
magnetic field
light
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Pending
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CN2011800327535A
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English (en)
Chinese (zh)
Inventor
A·兰佐尼
M·W·J·普林斯
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Koninklijke Philips NV
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Koninklijke Philips Electronics NV
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Application filed by Koninklijke Philips Electronics NV filed Critical Koninklijke Philips Electronics NV
Publication of CN103097894A publication Critical patent/CN103097894A/zh
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/49Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G01N2021/1727Magnetomodulation

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
CN2011800327535A 2010-07-02 2011-05-25 通过散射对致动的簇的探测 Pending CN103097894A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP10168221 2010-07-02
EP10168221.9 2010-07-02
EP11158688.9 2011-03-17
EP11158688 2011-03-17
PCT/IB2011/052265 WO2012001546A1 (en) 2010-07-02 2011-05-25 Detection of actuated clusters by scattering

Publications (1)

Publication Number Publication Date
CN103097894A true CN103097894A (zh) 2013-05-08

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ID=44303397

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011800327535A Pending CN103097894A (zh) 2010-07-02 2011-05-25 通过散射对致动的簇的探测

Country Status (6)

Country Link
US (1) US20120003750A1 (https=)
EP (1) EP2588861A1 (https=)
CN (1) CN103097894A (https=)
BR (1) BR112012033586A8 (https=)
IN (1) IN2013CN00308A (https=)
WO (1) WO2012001546A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2780692A1 (en) 2011-11-14 2014-09-24 Koninklijke Philips N.V. Apparatus for cluster detection
AU2014301652B2 (en) * 2013-06-28 2018-04-19 Cic Nanogune Biosensor based on measurements of the clustering dynamics of magnetic particles
EP3014244B1 (en) 2013-06-28 2017-03-15 Danmarks Tekniske Universitet (DTU) Biosensor based on the measurements of clustering dynamics of magnetic particles using a double pass setup
JP6727062B2 (ja) * 2015-09-30 2020-07-22 シスメックス株式会社 検出方法および検出装置
US12442756B2 (en) * 2020-09-04 2025-10-14 The Regents Of The University Of Colorado Method and system for determining at least one property of magnetic matter
TWI776251B (zh) * 2020-10-08 2022-09-01 中原大學 基於目標分子吸附之磁控量測系統
FR3157426A1 (fr) 2023-12-22 2025-06-27 IFP Energies Nouvelles Procédé amélioré de production de distillats moyens à partir d’hydrocarbures de synthèse en série à faible conversion par passe

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101558305A (zh) * 2006-12-12 2009-10-14 皇家飞利浦电子股份有限公司 用于检测标记颗粒的微电子传感器装置
WO2010026551A1 (en) * 2008-09-05 2010-03-11 Koninklijke Philips Electronics N.V. Rotating magnetic field for improved detection in cluster assays

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002035205A2 (en) * 2000-10-20 2002-05-02 Binax, Inc. Process for detecting or quantifying a biological reaction using superparamagnetic label
AU2002320058A1 (en) * 2001-06-06 2002-12-16 The General Hspital Corporation Magnetic-nanoparticle conjugates and methods of use
AU2002317095A1 (en) * 2001-07-03 2003-01-21 Governors Of The University Of Alberta Magnetic nanoparticles for bioseparation application and methods for producing same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101558305A (zh) * 2006-12-12 2009-10-14 皇家飞利浦电子股份有限公司 用于检测标记颗粒的微电子传感器装置
WO2010026551A1 (en) * 2008-09-05 2010-03-11 Koninklijke Philips Electronics N.V. Rotating magnetic field for improved detection in cluster assays

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANDREA RANZONI ET AL.: "Magnetically controlled rotation and torque of uniaxial microactuators for lab-on-a-chip applications", 《LAB ON A CHIP》, vol. 10, no. 2, 16 November 2009 (2009-11-16) *
ANIL K. VUPPUA ET AL.: "Phase sensitive enhancement for biochemical detection using rotating paramagnetic particle chains", 《JOURNAL OF APPLIED PHYSICS》, vol. 96, no. 11, 1 December 2004 (2004-12-01), XP012068383, DOI: doi:10.1063/1.1809269 *
SANG YOON PARK ET AL.: "Magneto-Optical Biosensing Platform Based on Light Scattering from Self-Assembled Chains of Functionalized Rotating Magnetic Beads", 《NANO LETTERS》, vol. 10, no. 2, 28 December 2009 (2009-12-28), pages 446 - 451, XP055051567, DOI: doi:10.1021/nl9030488 *
许公峰 等: "单链磁体及其研究进展", 《化学进展》, vol. 17, no. 6, 30 November 2005 (2005-11-30), pages 970 - 977 *

Also Published As

Publication number Publication date
BR112012033586A8 (pt) 2016-09-20
WO2012001546A1 (en) 2012-01-05
BR112012033586A2 (pt) 2016-08-16
IN2013CN00308A (https=) 2015-07-03
US20120003750A1 (en) 2012-01-05
EP2588861A1 (en) 2013-05-08

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Application publication date: 20130508