CN103082162A - Bee pollen granular preparation capable of direct compression and preparation method thereof - Google Patents
Bee pollen granular preparation capable of direct compression and preparation method thereof Download PDFInfo
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- CN103082162A CN103082162A CN201210450126XA CN201210450126A CN103082162A CN 103082162 A CN103082162 A CN 103082162A CN 201210450126X A CN201210450126X A CN 201210450126XA CN 201210450126 A CN201210450126 A CN 201210450126A CN 103082162 A CN103082162 A CN 103082162A
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Abstract
The invention discloses a bee pollen granular preparation capable of direct compression and a preparation method of the bee pollen granular preparation. The bee pollen granular preparation comprises the following main ingredients: bee pollen, magnesium stearate, vitamin B2, butter essence, and silicon dioxide or a non-viscous other material. The bee pollen granular preparation which can be directly compression-molded, is good in quality and less than 97% in bee pollen content, can be simply and conveniently produced by the method disclosed by the invention, a compressed tablet is complete, smooth and clean in appearance, angular, high in hardness, and low in friability, wherein the quality of the compressed tablet is superior to that of a bee pollen compressed tablet commonly seen in the market, especially, the hardness of the tablet is more than 3 times that of the common tablet, and the industrialized mass production of the bee pollen tablet can be well achieved.
Description
Technical field
The invention belongs to the health food technology field, be specifically related to a kind of Bee Pollen granular preparation and preparation method who can be used for direct tablet compressing that prepare in the wet granulation mode.
Background technology
Bee Pollen is the male sex-cell in the flowering plant stamen, it is not only carrying the hereditary information of life, and comprising and breeding the necessary complete nutrients matter of new life, be plant produce a male heir to continue the family line basic, can imagine the nutritive value of Bee Pollen thus, it is rich in 22 seed amino acids, 14 kinds of vitamin and 30 various trace elements and a large amount of active proteases, nucleic acid, flavone compound and other active material, it is the nutrition treasure of pure natural, natural health effect and medical treatment and its cosmetic values of present its uniqueness, be familiar with by increasing people, it is kind of a high protein and low fat nutritional health food, be described as " all-round nutraceutical " " concentrated natural Drug Storage " " cosmetics for oral administration " etc., it is the rarity in mankind's wholefood.
The effect of Bee Pollen aspect health care:
(1) strengthen the human body comprehensive immunologic function: pollen polysaccharide can activating macrophage engulfs activity, improves the human body resistance against diseases.
(2) anti-aging, beautification function: Bee Pollen belongs to the cosmetics of trophism, and the compositions such as the VE in pollen, superoxide dismutase (SOD), selenium can moisten the nutrition skin, the elasticity of recovery skin and bright and clean.Inositol in pollen can make the white hair blackening, and alopecia is gradually given birth to, and keeps hair pitch-black beautiful.
(3) control brain cardiovascular disease: the flavone compound in pollen can effectively be removed the deposition of fat on vascular wall, thereby plays softening blood vessel and reducing blood lipid.
(4) fat-reducing: take Bee Pollen and can absorb enough nutrition, cause satietion.Simultaneously, the fat of the lecithin incendivity surplus in pollen reaches the purpose of fat-reducing.
(5) regulate functions of intestines and stomach: pollen has many sterilization components, can kill Escherichia coli etc., and can prevent treating constipation.
(6) liver protecting: the flavone compound in pollen can prevent the deposition of fat on liver equally.
(7) regulate nervous system, promote sleep.
(8) auxiliary curing other diseases: pollen to anaemia, diabetes, improve memory, climacteric obstacle etc. better effects arranged.
The effect of Bee Pollen aspect medical:
(1) Bee Pollen treatment constipation effect is significant, efficiently reaches 95%.
(2) Bee Pollen contains nucleic acid, and after eating, it can make cytothesis, but delaying human body caducity and life-extending.The accumulation of lipofuscin in the brain cell of human body can affect the normal function of brain cell.Lipofuscin content increases, and can cause cellular atrophy and death.After edible Bee Pollen, each system enhancement of health is dispelled the brown pigment function and is strengthened, and the body aging process is slowed down, and brain memory power obviously improves, and testosterone, estradiol level increase, and the elderly's physique improves naturally, and senile plaque expelling reduces gradually and disappears.In Bee Pollen, contained selenium can reduce the formation of peroxide in addition, thereby plays anti-aging effects.
(3) pollen polysaccharide that contains has very strong immunocompetence, and effect significantly gives protection against cancer.
(4) pollen is prostatitic jinx, and the diseases such as chronic prostatitis, hyperplasia of prostate, prostatic function disorder are had significant result for the treatment of.Utilizing QIANLIE KANG TABLETS, the prostate of Bee Pollen (bee pollen food) development and production to tie up he, the medicine such as Xi Erni sheet both at home and abroad, is all the ideal medicament for the treatment of prostate class disease.
(5) Bee Pollen is conducive to impel the marrow that is wound restore funcitons as early as possible, can accelerate the reparation of hematopoietic tissue and the new life of haemocyte, is bringing into play positive effect to guaranteeing that hematopoiesis function runs well.
(6) Bee Pollen all has curative effect preferably to impotence, sex dysfunction and azoospermia, sterility etc., and menoxenia, dysmenorrhoea, menopause, nause gravidarum vomiting, climacteric are comprehensively combined and infertility etc. also has obvious auxiliary curative effect.In addition, diabetic's long-term taking Bee Pollen is evident in efficacy, with main ingredient, collaborative hypoglycemic effect is arranged.
In sum, Bee Pollen is having very high value of exploiting and utilizing really aspect the health-care hospital beauty treatment, but good product needed occurs by a good formulation, and Bee Pollen is mainly that the form with the former powder of broken wall occurs, and also having part is capsule and tablet.Tablet is the formulation of the most conveniently taking with industrialized production, Bee Pollen is having good prevention and result for the treatment of aspect urologic disease and prostatic diseases, these diseases often are accompanied by the difficult disadvantage of drinking water in a large number of patient, make high-quality tablets for this reason and seem particularly important.But Bee Pollen has the particularity that differs from ordinary raw material, general Bee Pollen all contains 20-25% protein, the amino acid of 20 kinds of left and right, the lipoid of 5-10%, the carbohydrate of 40-50%, the lignin of 10-15%, the compressibility of these most of materials wherein are not fine, although can make graininess preferably, but be difficult for compressing tablet, easily softening wire drawing goes out overlap, and the sub-difference of hardness of institute's compressing tablet reverts to again the particle former state after pinching out.The slice, thin piece that some Bee Pollen slice, thin pieces, particularly content on the market are higher is also that hardness is low, and the burr angle of collapsing is easily cracked, generally wrapped the slice, thin piece hardness of clothing also with regard to the 20N left and right, and Bee Pollen is gathered with saliva mediation balling-up by honeybee, and a kind of special peculiar smell is arranged, and ordinary person is difficult to adhere to taking.
Summary of the invention
The purpose of this invention is to provide a kind of Bee Pollen granular preparation and preparation method for direct tablet compressing, but can produce simply and easily the direct pressing moulding, high-quality, content is the Bee Pollen particle formulation below 97%, and institute's tablet agent outward appearance is complete bright and clean, and corner angle are clearly demarcated, hardness is high, friability is low, is better than the quality of the common bee pollen tablet in market, and especially hardness is high.
The present invention is achieved in that the Bee Pollen granular preparation for direct tablet compressing, and its feature will be in comprising following main component: Bee Pollen, dolomol, vitamin B2, butter essence, silica or noncohesive other material.
Bee Pollen of the present invention comprises rape pollen, zasiokaurin, camellia powder, sunflower powder, buckwheat pollen, sesame pollen, melon pollen, lotus powder, Chinese gall pollen and Pollen Codonopsis etc.
The preparation method of the Bee Pollen granular preparation for direct tablet compressing of the present invention is characterized in that comprising the following steps:
(1) appropriate silica is put in the high speed wet mixing pelletizer, throw and appropriate add a certain amount of natural or water artificial tanning agent to carry out wetting dispersion, be convenient to dye approach with Bee Pollen or the color and luster of demand voluntarily, then emit by required weighing standby;
(2) Bee Pollen is dropped in the high speed wet mixing pelletizer, add the wet feed of (1) institute weighing to stir granulation, form wet grain softwood;
(3) the wet grain softwood of making is transferred in fluidized dryer and is dried, the material sub-sieve that baking is good, the whole grain of chieftain, or the overall whole grain of siccative;
(4) material of sieve after whole adds the dolomol mixed pressuring plate, or adds other material to carry out mixed pressuring plate according to required formula.
But the present invention can produce the direct pressing moulding simply and easily, high-quality, content is the Bee Pollen particle formulation below 97%, institute's tablet agent outward appearance is complete bright and clean, and corner angle are clearly demarcated, and hardness is high, friability is low, the quality that is better than the common bee pollen tablet in market, especially hardness is more than 3 times of conventional slice, thin piece, can realize well industrialized production.
The specific embodiment
The Bee Pollen granular preparation that is used for direct tablet compressing, its feature will be in comprising following main component: Bee Pollen, dolomol, vitamin B2, butter essence, silica or noncohesive other material.Described Bee Pollen comprises rape pollen, zasiokaurin, camellia powder, sunflower powder, buckwheat pollen, sesame pollen, melon pollen, lotus powder, Chinese gall pollen and Pollen Codonopsis etc.The preparation method of described Bee Pollen granular preparation for direct tablet compressing, it is characterized in that comprising the following steps: (1) is put into appropriate silica in the high speed wet mixing pelletizer, throw and appropriate add a certain amount of natural or water artificial tanning agent to carry out wetting dispersion, be convenient to dye approach with Bee Pollen or the color and luster of demand voluntarily, then emit by required weighing standby; (2) Bee Pollen is dropped in the high speed wet mixing pelletizer, add the wet feed of (1) institute weighing to stir granulation, form wet grain softwood; (3) the wet grain softwood of making is transferred in fluidized dryer and is dried, the material sub-sieve that baking is good, the whole grain of chieftain, or the overall whole grain of siccative; (4) material of sieve after whole adds the dolomol mixed pressuring plate, or adds other material to carry out mixed pressuring plate according to required formula.during concrete enforcement, the height of slice, thin piece hardness is first started with from doing particle, we are through long development test for this reason, utilize the high-hydroscopicity of silica, in the high-speed stirred mixer-granulator, first allow its suction wetting, then put into and carry out rapid dispersion in the former powder of Bee Pollen of broken wall and granulate, form the particle of similar micropill, this particle particle bulk density is large, particle diameter is little, good fluidity, the particle of graininess is in the process of preparation oven dry like this, can water down preferably peculiar smell, presented original aromatic odor, or add flavor enhancement and allocate, can not only sell as grain products or tea granule separately, can also directly extrude the hardness higher than conventional Bee Pollen slice, thin piece, institute's sub-outward appearance of compressing tablet is complete bright and clean, corner angle are clearly demarcated, friability is low, hardness is more than 3 times of conventional slice, thin piece, make the quality of bee pollen tablet go up again a new step.
Further illustrate the present invention below by embodiment.
Embodiment 1:
Formula:
Silica: 9.5 parts (9.5%)
Bee Pollen (broken wall rape pollen): 90 parts (90.0%)
Dolomol: 0.5 part (0.5%)
1), according to wet granulation pot volume, the silica of Sq is dropped in pot, add that appropriate purified water stirs, chopping disperses, form softwood.
2), the gained softwood emits, clout in the chipping pot, taking 9.5 parts of silica, to add the wetting water yield standby.
3), drop into 90.0 parts of Bee Pollens in the wet granulation pot, add top alleged silica wet feed to carry out stirring fully the chopping dispersion and granulation, until make satisfied particle.
4), the oven dry of wet grain fluidisation, the sub-sieve that make, the whole grain of chieftain, or the overall whole grain of siccative.
5), the gained material is with 100 mesh sieves tests, 100 sieve 13.5% now, bulk density 0.55g/ml, moisture content: 5.5%, add 0.5% dolomol, with the stamping of ￠ 12.6mm circle, hardness: 75N.
Embodiment 2:
Formula:
Silica: 3.0 parts (3.0%)
Bee Pollen (broken wall rape pollen): 97.0 parts (97.0%)
1), according to wet granulation pot volume, the silica of Sq is dropped in pot, add that appropriate purified water stirs, chopping disperses, form softwood.
2), the gained softwood emits, clout in the chipping pot, taking 3.0 parts of silica, to add the wetting water yield standby.
3), drop into 97.0 parts of Bee Pollens in the wet granulation pot, add top alleged silica wet feed to carry out stirring fully the chopping dispersion and granulation, until make satisfied particle.
4), the oven dry of wet grain fluidisation, the sub-sieve that make, the whole grain of chieftain, or the overall whole grain of siccative.
5), the gained material is with 100 mesh sieves tests, 100 sieve 12.5% now, bulk density 0.50g/ml, moisture content: 4.8%, add 0.5% dolomol,, with the stamping of ￠ 12.6mm circle, hardness: 65N.
Embodiment 3:
Formula:
Silica: 5.0 parts (5.0%)
Bee Pollen (broken wall rape pollen): 93.4 parts (93.4%)
Vitamin B2
:Part 0.1 (0.1%)
Butter essence: 1.0 parts (1.0%)
Dolomol: 0.5 part (0.5%)
1), according to wet granulation pot volume, the silica of Sq is dropped in pot, add that the mixed liquor that is mixed with in right amount vitamin B2 stirs, chopping disperses, form softwood.
2), the gained softwood emits, clout in the chipping pot, taking 5.0 parts of silica, to add vitamin B2, the purified water of respective amount standby.
3), drop into 93.4 parts of Bee Pollens in the wet granulation pot, add top alleged silica wet feed to carry out stirring fully the chopping dispersion and granulation, until make satisfied particle.
4), the oven dry of wet grain fluidisation, the sub-sieve that make, the whole grain of chieftain, or the overall whole grain of siccative.
5), the gained material is with 100 mesh sieves tests, 100 sieve 12.5% now, bulk density 0.51g/ml, moisture content: 4.5%, add 0.5% dolomol, 1.0% butter essence is with the stamping of ￠ 12.6mm circle, hardness: 72N.
Claims (3)
1. the Bee Pollen granular preparation that is used for direct tablet compressing, its feature will be in comprising following main component: Bee Pollen, dolomol, vitamin B2, butter essence, silica or noncohesive other material.
2. the Bee Pollen granular preparation for direct tablet compressing according to claim 1, it is characterized in that: described Bee Pollen comprises rape pollen, zasiokaurin, camellia powder, sunflower powder, buckwheat pollen, sesame pollen, melon pollen, lotus powder, Chinese gall pollen and Pollen Codonopsis etc.
3. the preparation method of the Bee Pollen granular preparation for direct tablet compressing according to claim 1 is characterized in that comprising the following steps:
(1) appropriate silica is put in the high speed wet mixing pelletizer, throw and appropriate add a certain amount of natural or water artificial tanning agent to carry out wetting dispersion, be convenient to dye approach with Bee Pollen or the color and luster of demand voluntarily, then emit by required weighing standby;
(2) Bee Pollen is dropped in the high speed wet mixing pelletizer, add the wet feed of (1) institute weighing to stir granulation, form wet grain softwood;
(3) the wet grain softwood of making is transferred in fluidized dryer and is dried, the material sub-sieve that baking is good, the whole grain of chieftain, or the overall whole grain of siccative;
(4) material of sieve after whole adds the dolomol mixed pressuring plate, or adds other material to carry out mixed pressuring plate according to required formula.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210450126XA CN103082162A (en) | 2012-11-13 | 2012-11-13 | Bee pollen granular preparation capable of direct compression and preparation method thereof |
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| CN201210450126XA CN103082162A (en) | 2012-11-13 | 2012-11-13 | Bee pollen granular preparation capable of direct compression and preparation method thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103355678A (en) * | 2013-08-05 | 2013-10-23 | 彭常安 | Manufacturing method for haw-licorice decoction piece |
| CN103461989A (en) * | 2013-08-01 | 2013-12-25 | 丽江永胜边屯食尚养生园有限公司 | Safflower bee pollen tablet and preparation method thereof |
| CN103535575A (en) * | 2013-09-26 | 2014-01-29 | 张新军 | Novel formula and production technology of rose pollen tablet product |
| CN104886431A (en) * | 2015-06-09 | 2015-09-09 | 江苏日高蜂产品有限公司 | Bee pollen tablet and preparation technology thereof |
| CN105707801A (en) * | 2016-03-03 | 2016-06-29 | 扬州三邦生物工程有限公司 | Bee pollen and preparing method thereof |
| CN105767997A (en) * | 2016-03-03 | 2016-07-20 | 扬州三邦生物工程有限公司 | Bee pollen and preparation method thereof |
| CN107048295A (en) * | 2017-04-18 | 2017-08-18 | 甘肃省医学科学研究院 | A kind of peony pollen buccal tablet and preparation method thereof |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103461989A (en) * | 2013-08-01 | 2013-12-25 | 丽江永胜边屯食尚养生园有限公司 | Safflower bee pollen tablet and preparation method thereof |
| CN103461989B (en) * | 2013-08-01 | 2015-07-08 | 丽江永胜边屯食尚养生园有限公司 | Safflower bee pollen tablet and preparation method thereof |
| CN103355678A (en) * | 2013-08-05 | 2013-10-23 | 彭常安 | Manufacturing method for haw-licorice decoction piece |
| CN103535575A (en) * | 2013-09-26 | 2014-01-29 | 张新军 | Novel formula and production technology of rose pollen tablet product |
| CN104886431A (en) * | 2015-06-09 | 2015-09-09 | 江苏日高蜂产品有限公司 | Bee pollen tablet and preparation technology thereof |
| CN105707801A (en) * | 2016-03-03 | 2016-06-29 | 扬州三邦生物工程有限公司 | Bee pollen and preparing method thereof |
| CN105767997A (en) * | 2016-03-03 | 2016-07-20 | 扬州三邦生物工程有限公司 | Bee pollen and preparation method thereof |
| CN107048295A (en) * | 2017-04-18 | 2017-08-18 | 甘肃省医学科学研究院 | A kind of peony pollen buccal tablet and preparation method thereof |
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Application publication date: 20130508 |