CN103082095A - Application of triglyceryl lactate as feed acidifier - Google Patents

Application of triglyceryl lactate as feed acidifier Download PDF

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CN103082095A
CN103082095A CN2013100399661A CN201310039966A CN103082095A CN 103082095 A CN103082095 A CN 103082095A CN 2013100399661 A CN2013100399661 A CN 2013100399661A CN 201310039966 A CN201310039966 A CN 201310039966A CN 103082095 A CN103082095 A CN 103082095A
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feed
lactate
triglyceryl
animals
application
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CN103082095B (en
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侯永清
丁斌鹰
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Hubei Haohua Biotechnology Co ltd
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WUHAN PAN-CHINA BIOTECHNOLOGY Co Ltd
Wuhan Polytechnic University
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Abstract

The invention discloses application of an organic compound. The technical characteristic is as follows: the application objects of triglyceryl lactate as a feed acidifier include monogastric animals such as pigs, poultry and the like, ruminants such as cows, sheep and the like, herbivores such as horses, rabbits and the like or fishes, shrimps and crabs. The application method comprises the following steps of: directly adding 0.05-1.0% of the triglyceryl lactate into the feed based on the total weight of the feed; or mixing the triglyceryl lactate with an adsorbent to obtain a premix; or mixing the triglyceryl lactate with other feed additives or feed raw materials to obtain a premix or a concentrate to feed monogastric animals such as pigs, poultry and the like, ruminants such as cows, sheep and the like, herbivores such as horses, rabbits and the like and aquatic animals such as fishes, shrimps, crabs and the like. Through the invention, the triglyceryl lactate is slowly decomposed in the alimentary canals of animals while releasing the characteristics of lactic acid, the pH value of the gastrointestinal tract is reduced, the growth of harmful bacteria in the gastrointestinal tract is suppressed, the reproduction of beneficial bacteria is promoted, and an effect of improving gastrointestinal microecology of animals is realized so as to promote the animal health and improve the production performance.

Description

Three glyceride lactates are as the application of fodder acidulant
Technical field
The present invention relates to the purposes of three glyceride lactates, relate in particular to the purposes in animal feed acidulant field.
Background technology
Add acidulant in feed and can reduce animal gastrointestinal tract pH value, promote digesting and assimilating of nutriment, suppress the breeding of harmful intestinal tract microorganism, improve the animal body immunocompetence, minimizing stress, the promotion growth of animal.Existing fodder acidulant mainly is made of inorganic acid and organic acid, so this class acidulant exists easily at the animal stomach and is absorbed and can not effectively arrives the shortcoming of hindgut.In order to make acidulant effectively arrive hindgut, the coating techniques that adopt solve more at present, and the cost of this technology is higher, coating rate is unstable, thereby has hindered the marketing of this series products.Therefore, the fodder acidulant that need to seek to be more suitable for is used for reducing animal gastrointestinal tract pH value, promotes the micro ecology of gastrointestinal tract balance, and prevention animal intestinal bacteriosis improves cultivation efficient.
Under field conditions (factors), lactic acid in alimentary canal is mainly produced through the anaerobic bacteria glycolysis in the animal hindgut by carbohydrate such as the lactose in feed, SNSPs, it not only provides energy for rat gut mucosa, can also suppress the pernicious bacterias such as the interior Escherichia coli of enteron aisle, salmonella, promote the growth of the beneficial bacteriums such as lactic acid bacteria.
Lactic acid often directly is used as fodder acidulant and uses, and lactic acid is the feed addictive that country allows use, and main application is exactly acidifying.But lactic acid is after entering alimentary canal, mainly in the anterior absorption of alimentary canal, especially in stomach, therefore be difficult to play a role at alimentary canal rear portion (small intestine back segment, colon or caecum etc.), therefore, lactic acid can not effectively reduce alimentary canal back segment pH, reaches to regulate rear intestinal segment effects of microflora.
Lactic acid and glycerine esterification generate three glyceride lactates, molecular formula, C 12H 20O 9, molecular weight: 308.28, structural formula is:
Figure BDA0000280557151
Existing file shows, three glyceride lactates do not retrieve mainly as grease and NMF the technical scheme that three glyceride lactates are used as the animal feed acidulant.
Summary of the invention
The purpose of this invention is to provide a kind of fodder acidulant.
Technical problem to be solved by this invention is to provide the new purposes of three glyceride lactates, namely as the new application of fodder acidulant.
The technical solution adopted for the present invention to solve the technical problems.Three glyceride lactates meet molecular formula as the application of fodder acidulant, C 12H 20O 9, molecular weight: 308.28, structural formula is:
After three glyceride lactates enter alimentary canal, do not absorb at alimentary canal anterior (in stomach), enter the alimentary canal back segment and resolved into glycerine and lactic acid by the secreted lipase of pancreas.Therefore, three glyceride lactates are slowly decomposed in alimentary canal, and lactic acid is slowly released.Three glyceride lactates have following characteristics, and the first, can not produce in animal body the bad property accumulated and specific reaction; Second, for lactic acid or lactate, the decomposable process of three glyceride lactates is processes of biological slow-released lactic acid, and therefore this lactic acid can arrive rear intestinal segment, performance reduces the rear intestinal pH such as small intestine back segment, colon or caecum, and then promotes the micro ecology of gastrointestinal tract balance.
Three glyceride lactates of the present invention are realized by the following method as the using method of fodder acidulant:
Three glyceride lactates, addition are 0.05%~1.0% of feed gross weight, directly it are added in feed; Or add to again in feed after itself and adsorbent are mixed and made into pre-mixing agent; Also can be mixed and made into the forms such as premix, concentrate feed with other feed addictive or feedstuff adds in feed again.
Three glyceride lactates of the present invention are as the application of fodder acidulant, and application is the aquatic livestocks such as the plant-eating animals such as ruminant, horse rabbit such as the nonruminants such as pig fowl, cattle and sheep of artificial feeding and fish shrimp crab.
The advantage that the present invention has is:
1. three glyceride lactates, under the effect of animal tallow enzyme, catabolite is lactic acid and glycerine in vivo, both is normal metabolite in animal body, and is without any side effects to human and animal's body.
2. three glyceride lactates are as fodder acidulant, and decomposition slowly releases lactic acid in animal alimentary canal, can effectively reduce the pH of alimentary canal back segment, effectively reduce growing of pernicious bacteria, promote the breeding of profitable strain, the regulating intestinal canal microecological balance, thus promote growth of animal.
3. before not being decomposed, it is neutral that three glyceride lactates are, and do not produce excitant and corrosivity effect, and have certain aromatic odor, improves the palatability of feed.
4, before not being decomposed, three glyceride lactates can be avoided feed, and especially in premix, the nutriments such as vitamin, mineral matter must destroy, and avoid the acid corrosion of feed-processing equipment is damaged.
So, three glyceride lactates are fodder acidulants desirable in the animal-breeding process, use three glyceride lactates and slowly decomposed the feature that discharges lactic acid in animal alimentary canal, reduce intestines and stomach pH value, suppress the growth of harmful intestinal tract bacteria, the breeding of promotion beneficial bacterium, reach the effect of improving the little ecology of animal intestinal, and then promote animal health and improve production performance.
The specific embodiment
Embodiment 1
Select 21 ± 1 age in days wean, Du * long * 100 of large piglets, be divided at random 2 processed group (control group and test group) by the close principle of body weight.5 repetitions (hurdle) are established in each processing, 10, every hurdle piglet.Feed corn bean pulp type and add three glyceride lactates of feed gross weight 0.3% of control group fed corn bean pulp type daily ration, test group was raised after 21 days, measured Growth Performance of Weaning Piglets, enteron aisle chyme pH and faecal flora quantity.The results are shown in Table 1, table 2.
Table 1 duration of test Growth Performance of Weaning Piglets
Figure BDA0000280557153
Annotate: indicate different lowercases with the right shoulder of column of figure, expression significant difference (P<0.05).Below roughly the same.
Table 1 data show, duration of test and control group ratio, add 0.3% 3 glyceride lactate in the weanling pig daily ration, improve average daily ingestion amount 2.90%, average daily gain 9.43%, reduction material anharmonic ratio 6.21% and Incidence of Diarrhea 41.64%(P<0.05 of weanling pig).Therefore, three glyceride lactates have promoted the growth of weanling pig, have reduced diarrhoea and have occured.
Table 2 Gastrointestinal Tract of Weanling Piglets Chyme pH and faecal flora quantity
Figure BDA0000280557154
Table 2 data show, during off-test, the pH value of Gastrointestinal Tract of Weanling Piglets chyme is subject to adding in daily ration the impact of 0.3% 3 glyceride lactate, compares with control group, significantly reduced small intestine pH value 0.22(P<0.05), reduced stomach pH value 0.25(P>0.05).Three glyceride lactates significantly reduce Escherichia coli quantity 5.29%(P<0.05 in the colon chyme), improved the quantity 6.72%(P of lactic acid bacteria<0.05).Therefore, add three glyceride lactates in the weanling pig daily ration and can reduce intestines and stomach chyme pH, improve the quantity of colon lactic acid bacteria, reduce colibacillary quantity, regulate the hindgut micro-ecological environment.
Embodiment 2
Select 200 of 1 age in days Cobb meat chicks, be divided at random 2 processed group (control group and test group) by the close principle of body weight.5 repetitions (hurdle) are established in each processing, 10, every hurdle (male and female half and half).Feed corn bean pulp type and add three glyceride lactates of feed gross weight 0.05% of control group fed corn bean pulp type daily ration, test group was raised after 42 days, measured growth of meat chicken performance and empty, caecum micro organism quantity.The results are shown in Table 3,4.
Table 3 duration of test growth of meat chicken performance
Table 3 data show, duration of test and control group ratio, add feed gross weight 0.05% 3 glyceride lactate in broiler fodder, improved the average feed intake of broiler chicken, significantly improved average weight gain 12.64% and 10.22%, reduction material anharmonic ratio 8.29% and 5.09%(P<0.05 of 0~21d and 0~42d).Therefore, three glyceride lactates have promoted the growth of broiler chicken, have improved the growth of meat chicken performance.
Table 4 broiler chicken jejunum and caecum micro organism quantity
Figure BDA0000280557156
Table 4 data show, during off-test, compare with control group, add 0.05% 3 glyceride lactate and reduced respectively Escherichia coli quantity 22.53% and 20.43%(P<0.05 in broiler chicken jejunum and caecum), improved quantity 13.43% and 8.10%(P<0.05 of lactic acid bacteria).Therefore, add three glyceride lactates and can improve the quantity of colon lactic acid bacteria in the meat chick fodder, reduce colibacillary quantity, the regulating intestinal canal micro-ecological environment.
Embodiment 3
Selecting body weight is hybridized prussian carp 240 tails of 5.35 ± O.02 g, and Random assignment is divided into 2 processed group in 8 aquariums, adds respectively three glyceride lactates (O%, 1.0%) of different gradient levels, every group of 4 repetitions, every repetition 30 tail fishes.By the growth test in 8 weeks, estimate three glyceride lactates to the impact of allogynogenetic crucian carp performance.The results are shown in Table 5.
Table 5 duration of test allogynogenetic crucian carp performance
The relative weight gain rate % Specific growth rate % Feed coefficient Survival rate %
Control group 778.41±59.12 b 3.88±0.12 b 1.45±0.05 a 95.80±5.0
Test group 837.50±19.67 a 4.00±0.04 a 1.42±0.03 b 96.70±2.27
Table 5 data show, add 0.1% 3 glyceride lactate and can improve the relative weight gain rate 7.59% and specific growth rate 3.09%(P<0.05 in the feed of hybridized prussian carp), reduce feed coefficient 2.07%(P<0.05), promoted the growth of hybridized prussian carp.

Claims (2)

1. the purposes of an organic compound is characterized in that: three glyceride lactates are as the application of fodder acidulant, and application comprises the feed of pig fowl nonruminant or cattle and sheep ruminant or horse rabbitweed food animal or fish shrimp crab.
2. three glyceride lactates according to claim 1 as the application of fodder acidulant, is characterized in that: using method be addition according to feed gross weight meter, be 0.05%~1.0%, directly this product is added in feed; Or this product and adsorbent are mixed and made into pre-mixing agent; Or be mixed and made into premix or concentrate feed feed pig fowl nonruminant or cattle and sheep ruminant or horse rabbitweed food animal or fish shrimp crab aquatic livestock with other feed addictive or feedstuff.
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104304675A (en) * 2014-10-13 2015-01-28 武汉轻工大学 Antibacterial feed additive and application
CN108185189A (en) * 2018-03-16 2018-06-22 武汉市农业科学院 Feed active compound composition, feed addictive, feed and preparation method
CN108208341A (en) * 2017-12-29 2018-06-29 湖北浩华生物技术有限公司 Purposes, feed addictive and feed of the fat or oil composition on pig feed additive for fowls is prepared
CN109497340A (en) * 2018-12-27 2019-03-22 皖西学院 A kind of poultry farming health ecological feed additive
CN110402857A (en) * 2019-08-30 2019-11-05 三亚福联水产发展有限公司 A kind of grouper quick-breeding method
CN112205527A (en) * 2019-07-11 2021-01-12 中粮生物化学(安徽)股份有限公司 Acidifier and preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1513347A (en) * 2003-07-24 2004-07-21 侯永清 Application os glycerin tributyrate as feed additive
CN101119648A (en) * 2005-02-14 2008-02-06 弗尔南多·坎提尼 Mixtures of fatty acid glycerides from C1 to C22 to improve zootechnical performances and/or the health of the intestine of animals
CN102204633A (en) * 2011-05-17 2011-10-05 张婷丽 Application of glyceryl tripropionate as feed acidifier

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1513347A (en) * 2003-07-24 2004-07-21 侯永清 Application os glycerin tributyrate as feed additive
CN101119648A (en) * 2005-02-14 2008-02-06 弗尔南多·坎提尼 Mixtures of fatty acid glycerides from C1 to C22 to improve zootechnical performances and/or the health of the intestine of animals
CN102204633A (en) * 2011-05-17 2011-10-05 张婷丽 Application of glyceryl tripropionate as feed acidifier

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104304675A (en) * 2014-10-13 2015-01-28 武汉轻工大学 Antibacterial feed additive and application
CN108208341A (en) * 2017-12-29 2018-06-29 湖北浩华生物技术有限公司 Purposes, feed addictive and feed of the fat or oil composition on pig feed additive for fowls is prepared
CN108208341B (en) * 2017-12-29 2021-11-30 湖北浩华生物技术有限公司 Application of grease composition in preparation of pig and poultry feed additive, feed additive and feed
CN108185189A (en) * 2018-03-16 2018-06-22 武汉市农业科学院 Feed active compound composition, feed addictive, feed and preparation method
CN108185189B (en) * 2018-03-16 2021-04-16 武汉市农业科学院 Active substance composition for feed, feed additive, feed and preparation method
CN109497340A (en) * 2018-12-27 2019-03-22 皖西学院 A kind of poultry farming health ecological feed additive
CN109497340B (en) * 2018-12-27 2022-03-01 皖西学院 Health-care ecological feed additive for poultry breeding
CN112205527A (en) * 2019-07-11 2021-01-12 中粮生物化学(安徽)股份有限公司 Acidifier and preparation method and application thereof
CN110402857A (en) * 2019-08-30 2019-11-05 三亚福联水产发展有限公司 A kind of grouper quick-breeding method
CN110402857B (en) * 2019-08-30 2021-12-03 三亚福联水产发展有限公司 Rapid propagation method for grouper

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