CN103071210B - A kind of needle point has the syringe needle of bionic form - Google Patents
A kind of needle point has the syringe needle of bionic form Download PDFInfo
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- CN103071210B CN103071210B CN201310020610.3A CN201310020610A CN103071210B CN 103071210 B CN103071210 B CN 103071210B CN 201310020610 A CN201310020610 A CN 201310020610A CN 103071210 B CN103071210 B CN 103071210B
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- needle
- needle point
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Abstract
The present invention relates to a kind of needle point and there is the syringe needle of bionic form. It is applied to the disposable interventional medical device field of the processes such as clinical transfusion, puncture, sampling. It is characterized in that, the needle point outside wall surface (3) of described syringe needle or pinpoint inclined plane (4) have macroscopic view or microcosmic biomimetic features form. Biomimetic features include stripe-shaped, dimple-shaped, corrugated three kinds. The purpose adding bionic form in needle tip is to reduce the frictional force that in injection piercing process, needle point is subject to, and reduces the needle point stimulation to underlying nerve tip in piercing process, it is achieved subtract pain effect.
Description
Technical field
The present invention relates to a kind of needle point and there is the syringe needle of bionic form. It is applied to the disposable interventional medical device field of the processes such as clinical transfusion, puncture and sampling.
Background technology
The interventional therapys such as drug injection, puncture sampling are the Main Means of clinical treatment. And inject, skin histology is damaged in piercing process, makes teleneuron experience stimulation thus producing pain, the puzzlement that this process is brought to patient can not be ignored. Pursuing under the overall background of life Happiness current people, effectively reducing injection pain is reduce Medical fear, the effective means of raising people's quality of life. Owing to, the mankind are from birth vaccinates beginning, just must start the injection pain problem in the face of coexisting with drug effect, therefore, be effectively reduced the injection of patient, puncture pain and body injury is one of the Main way of current medical device research.
At present, the existing research for drug injection pain mechanism of production shows, injection pain comes from syringe needle and thrusts the algogenic substance that skin makes cell rupture discharge. For induced pain mechanism, existing painless injection method mainly has (1) microneedle injection. With microneedle array for representative, by reducing the mode of needle tubing diameter, effectively reduce skin injury area and algogenic substance produces quantity, thus realizing painless injection purpose. But, the advantage that micropin needle tubing diameter is little, while reducing pain, limit the effect of drug absorption, thus its scope of application is confined to efficient, a small amount of drug injection. (2) Needleless injection. Utilize high-pressure spray that drug particles is directly squeezed into subcutaneous a kind of painless injection technology. But, owing to the supplementary instrument needed for realizing high-pressure spray is more, with high costs, so the popularization difficulty of Needleless injection is bigger. (3) fast injection. Employing inserting needle is fast, push away medicine slowly, pull out the two fast one slow methods that pin is fast, alleviates injection to a certain extent and keenly feels. But, this method is subject to the impact of patient's subjective factors in actual applications, and different patient's results of use are different, and effect is unstable. (4) laser injection. Utilize laser ablation trace epidermis, make insulin be directly entered human body, reach painless purpose. But, its applicable medicine is single, still can not promote on a large scale. (5) meridians are massaged and Acupressure.As its name suggests, it is a kind of technical skill being slowed down injection pain by manipulation of massage. But, its effect is very notable, and is not particularly suited for everyone, such as anemia of pregnant woman, so only as the supplementary means subtracting pain. (6) bionical needle injection. On needle tubing outer wall, processing has spiral type, corrugated, zigzag or dimple-shaped biomimetic features, by reducing the mode of the frictional resistance between syringe needle and skin histology, reduces the stimulation to teleneuron in injection process, reaches to subtract the purpose of pain. But, the method only takes into account the frictional resistance of needle tubing part, it does not have relate to the drag reduction of tip portion. And needle point penetration Resistance is generally 2-3 times of needle tubing frictional resistance, thus, reducing the minimizing needle tubing frictional resistance of the penetration Resistance ratio of needle point, meaning is more great. Therefore, what we this time proposed invents the syringe needle for the needle point that can reduce penetration Resistance with bionic form.
Summary of the invention
It is an object of the invention to overcome above-mentioned many disadvantages and the deficiency of existing painless injection mode, it is provided that a kind of needle point has the syringe needle of bionic form. By changing the mode of needle surface form, reducing the frictional resistance between needle point and skin histology in drug injection piercing process, thus reducing the injection process stimulation to teleneuron, reaching to reduce the purpose of injection pain.
The above-mentioned purpose of the present invention is achieved through the following technical solutions, and accompanying drawings is as follows:
A kind of needle point has the syringe needle of bionic form, and its needle point outside wall surface or pinpoint inclined plane have the biomimetic features of bionic form, and described bionic form is stripe-shaped, dimple-shaped or corrugated; It is divided into macroscopic view, microcosmic two kinds by bionic form size; It is divided into needle point outside wall surface, pinpoint inclined plane two kinds by bionic form position; The cross section of described stripe-shaped bionic form is rectangular or del; The cross section of described dimple-shaped bionic form is circular arc; The cross section of described corrugated bionic form is corrugated. Described stripe-shaped and corrugated biomimetic features, its arragement direction is axially vertical with syringe needle; Described dimple-shaped biomimetic features, its arrangement mode on needle point is rectangular or rhombus.
Described biomimetic features being distributed as all or local on needle point.
When described biomimetic features is macroscopic form, the groove depth 0.01-0.05mm of striped form, groove width 0.01-0.10mm, spacing 0.02-0.10mm, the pit depth 0.01-0.05mm of concave state, diameter 0.01-0.10mm, spacing 0.02-0.10mm, the ripple's depth 0.01-0.05mm of corrugations, width 0.01-0.10mm, spacing 0.02-0.10mm.
When described biomimetic features is microscopic pattern, be etched or sandblasting go material partial depth 1-10nm, width 1-10nm, spacing 1-20nm.
The processing method of macroscopic view biomimetic features form is laser ablation; The processing method of microcosmic biomimetic features form is sandblasting or chemical etching.
A kind of needle point has the syringe needle of bionic form, and the needle point outside wall surface of described syringe needle or pinpoint inclined plane have biomimetic features; According to bionic form be divided into stripe-shaped, dimple-shaped, corrugated three kinds; It is divided into macroscopic view, microcosmic two kinds according to bionic form size.
The present invention is the syringe needle that needle point has bionic form, can be used for the biological tissue puncture injections such as intravenous needle, intramuscular injection pin, blood taking needle, living body sampling pin, body fluid drainage needle, punctures medical treatment intervention apparatus. Its Clinical practice mode, method are identical with conventional syringe syringe needle, without special operational instructions for use.
The solution have the advantages that:
This syringe needle, by processing biomimetic features form in the needle point outside wall surface or pinpoint inclined plane of standard syringe syringe needle, reduces the frictional resistance between needle point and skin histology, it is achieved reduce the purpose of pain when injection or puncture.Generally, in injection, piercing process, pain is mostly derived from the neural perception to algogenic substance, and algogenic substance comes from the histiocyte that syringe needle is destroyed under the effect of frictional force between the two with skin histology contact process. Needle point disclosed by the invention has the syringe needle of bionic form, needle point and the contact area of skin histology in injection, piercing process can be reduced, reduce frictional resistance between the two, so that histiocyte destructiveness decreases, the algogenic substance discharged reduces, and injection pain reduces.
Accompanying drawing explanation
Fig. 1 (a) is the needle head structure schematic diagram of the present invention;
Fig. 1 (b) is the needle point partial enlarged drawing of Fig. 1 (a);
Fig. 1 (b1) is the stripe-shaped on Fig. 1 (b) basis and corrugated pinpoint inclined plane biomimetic features partial enlarged drawing;
Fig. 1 (b2) is the dimple-shaped pinpoint inclined plane biomimetic features partial enlarged drawing on Fig. 1 (b) basis;
Fig. 1 (c) is the needle point partial enlarged drawing of Fig. 1 (a);
Fig. 1 (c1) is the stripe-shaped needle point outside wall surface biomimetic features partial enlarged drawing on Fig. 1 (c) basis;
Fig. 1 (c2) is the corrugated needle point outside wall surface biomimetic features partial enlarged drawing on Fig. 1 (c) basis;
Fig. 1 (c3) is the dimple-shaped needle point outside wall surface biomimetic features partial enlarged drawing on Fig. 1 (c) basis;
Fig. 1 (d1), (d2) are stripe-shaped biomimetic features cross section Local map;
Fig. 1 (d3) is dimple-shaped biomimetic features cross section Local map;
Fig. 1 (d4) is corrugated biomimetic features cross section Local map.
Fig. 2 is dimple-shaped biomimetic features distribution mode schematic diagram, wherein:
Fig. 2 (a) is by the rectangular distribution;
Fig. 2 (b) is distributed by rhombus.
Fig. 3 (a) be for cross section be zigzag striated structure the biomimetic features degree of depth, width, spacing schematic diagram;
Fig. 3 (a1) be for cross section be zigzag striated structure the biomimetic features degree of depth, width, spacing schematic diagram (pinpoint inclined plane);
Fig. 3 (a2) be for cross section be zigzag striated structure the biomimetic features degree of depth, width, spacing schematic diagram (needle point outside wall surface);
Fig. 3 (b) is the biomimetic features degree of depth of the dimple-shaped structure for distributed rectangular, diameter, spacing schematic diagram;
Fig. 3 (b1) is the biomimetic features degree of depth of the dimple-shaped structure for distributed rectangular, diameter, spacing schematic diagram (pinpoint inclined plane);
Fig. 3 (b2) is the biomimetic features degree of depth of the dimple-shaped structure for distributed rectangular, diameter, spacing schematic diagram (needle point outside wall surface);
Fig. 3 (c) is the degree of depth of corrugated biomimetic features, width, spacing schematic diagram;
Fig. 3 (c1) is the degree of depth of corrugated biomimetic features, width, spacing schematic diagram (pinpoint inclined plane);
Fig. 3 (c2) is the degree of depth of corrugated biomimetic features, width, spacing schematic diagram (needle point outside wall surface);
Fig. 4 is the application schematic diagram in other types injection, puncture instrument.
In accompanying drawing 1, needle tubing connect seat, 2, needle tubing surface, 3, needle point, 4, bionic form on pinpoint inclined plane, 5, the range of work, 6, distributed rectangular, 7 rhombuses distributions, 8, spacing, 9, width, 10, diameter, 11, the degree of depth, 12, sub-pin, 13, female pin, 14, bionic surface
Detailed description of the invention
Further illustrate below in conjunction with the particular content to the present invention of the example shown in accompanying drawing and embodiment.
A kind of needle point has the syringe needle of bionic form, is made up of the biomimetic features on syringe needle and needle point, biomimetic features therein, is divided into both macro and micro two kinds by size;By shape be divided into stripe-shaped, dimple-shaped, corrugated three kinds; Opsition dependent is divided into needle point outside wall surface and pinpoint inclined plane two kinds.
The size range of pinpoint inclined plane biomimetic features: during macroscopic form, the groove depth 0.01-0.05mm of striped form, groove width 0.01-0.10mm, spacing 0.02-0.10mm, the pit depth 0.01-0.05mm of concave state, diameter 0.01-0.10mm, spacing 0.02-0.10mm, the ripple's depth 0.01-0.05mm of corrugations, width 0.01-0.10mm, spacing 0.02-0.10mm; During microscopic pattern, be etched or sandblasting go material partial depth 1-10nm, width 1-10nm, spacing 1-20nm.
The distribution of biomimetic features can take up whole needle point, it is also possible to exists only in local.
The present invention is the syringe needle that needle point has bionic form, on the medical treatment interventional instruments such as the venoclysis needle that can be applicable to the injection of clinical treatment field Chinese medicine, need to use when puncturing sampling, intramuscular injection pin, blood taking needle, biopsy needle. Its Clinical practice is identical with conventional syringe syringe needle, without special operational instructions for use.
The method have the characteristics that the biomimetic features form on needle point. For intramuscular injection pin, having biomimetic features in syringe needle needle point outside wall surface 3 or pinpoint inclined plane 4, bionical female area accounts within needle surface is long-pending 30%, and its depression distribution can consult Fig. 1 and Fig. 2. In Clinical practice, due to the effect of bionical shape depression on needle point, decrease needle point and thrust the real contact area in process and between skin histology, make histiocytic destructiveness in the process of thrusting decline, the algogenic substance discharged reduces, and the stimulation of teleneuron is weakened. Syringe needle disclosed by the invention, its using method and conventional syringe syringe needle are as good as, and user is not had SOR, and by user because syringe needle penetration Resistance reduces, the pain being subject to reduces.
Consulting Fig. 4, the bionic form on needle point can be used for injection, the Centesis instrument such as venoclysis needle, biopsy male/female needle 12,13. Different according to syringe needle model, its biomimetic features arrangement mode can suitably adjust, but need to ensure that needle surface shared by bionical recess is long-pending less than 30%. Its painless principle is identical, is all the mode by reducing the real contact area between syringe needle and skin histology, it is achieved subtract pain effect.
Macroscopic view biomimetic features form can be obtained by laser ablation; Microcosmic biomimetic features form can be obtained by sandblasting or chemical etching.
Claims (1)
1. needle point has a syringe needle for bionic form, the biomimetic features that described bionic form adopts being distributed as all or local on needle point, it is characterised in that: needle point outside wall surface and pinpoint inclined plane have the biomimetic features of bionic form;
Described bionic form is stripe-shaped, dimple-shaped or corrugated; It is divided into macroscopic view, microcosmic two kinds by bionic form size; It is divided into needle point outside wall surface, pinpoint inclined plane two kinds by bionic form position; The cross section of described stripe-shaped bionic form is rectangular or del; The cross section of described dimple-shaped bionic form is circular arc; The cross section of described corrugated bionic form is corrugated;
Described stripe-shaped and corrugated biomimetic features, its arragement direction is axially vertical with syringe needle; Described dimple-shaped biomimetic features, its arrangement mode on needle point is rectangular or Pedicellus et Pericarpium Trapae shape;
When described biomimetic features is macroscopic form, the groove depth 0.01-0.05mm of striped form, groove width 0.01-0.10mm, spacing 0.02-0.10mm, the pit depth 0.01-0.05mm of concave state, diameter 0.01-0.10mm, spacing 0.02-0.10mm, the ripple's depth 0.01-0.05mm of corrugations, width 0.01-0.10mm, spacing 0.02-0.10mm;
When described biomimetic features is microscopic pattern, be etched or sandblasting go material partial depth 1-10nm, width 1-10nm, spacing 1-20nm.
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CN201310020610.3A CN103071210B (en) | 2013-01-19 | 2013-01-19 | A kind of needle point has the syringe needle of bionic form |
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CN201310020610.3A CN103071210B (en) | 2013-01-19 | 2013-01-19 | A kind of needle point has the syringe needle of bionic form |
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Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104971406A (en) * | 2015-05-22 | 2015-10-14 | 南京农业大学 | Medical needle with micro-reflector structure on surface and preparation method thereof |
CN105169534A (en) * | 2015-08-10 | 2015-12-23 | 苏州灵岩医疗科技股份有限公司 | Needle tip for injection |
CN108478908A (en) * | 2018-05-07 | 2018-09-04 | 吉林大学 | A kind of bionical painless syringe syringe needle |
CN109699600B (en) * | 2019-01-29 | 2021-01-22 | 陕西科技大学 | Underwater drag reduction bionic micro-nano structure |
CN113936520B (en) * | 2021-10-14 | 2022-06-21 | 中国人民解放军总医院第四医学中心 | Radio frequency ablation simulation training device |
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CN1765428A (en) * | 2005-11-18 | 2006-05-03 | 吉林大学 | Painless syringe |
CN1856334A (en) * | 2003-08-05 | 2006-11-01 | 贝克顿·迪金森公司 | Syringe having a multi-bevel needle |
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CN201008687Y (en) * | 2007-03-27 | 2008-01-23 | 武汉大学 | Syringe needle head |
CN101810897B (en) * | 2010-05-06 | 2011-12-28 | 吉林大学 | Injection needle with spiral surface |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN1856334A (en) * | 2003-08-05 | 2006-11-01 | 贝克顿·迪金森公司 | Syringe having a multi-bevel needle |
CN1765428A (en) * | 2005-11-18 | 2006-05-03 | 吉林大学 | Painless syringe |
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