CN103071210A - Injector needle head with needle point in bionic form - Google Patents

Abstract

The invention relates to an injector needle head with a needle point in a bionic form, which is applied to the field of disposable intervention medical appliances in the processes of clinical infusion, puncture, sampling and the like. The injector needle head is characterized in that the needle point outer wall face (3) or the needle point inclined surface (4) of the injector needle head has a macroscopic or microscopic bionic structural form. A bionic structure comprises a strip-shaped structure, a pit-shaped structure and a corrugated structure. The bionic form is added to the needle point of the needle head to reduce the friction force on the needle point in injection and puncture processes, reduce the stimulation effect of the needle point on subcutaneous nerve endings in a puncture process and achieve the effect of relieving pain.

Description

A kind of needle point has the syringe needle of bionical form

Technical field

The present invention relates to the syringe needle that a kind of needle point has bionical form.Be applied to the disposable interventional medical device field of the processes such as clinical transfusion, puncture and sampling.

Background technology

The interventional therapys such as drug injection, puncture sampling are the Main Means of clinical treatment.And inject, skin histology is damaged in the piercing process, thereby teleneuron being experienced stimulate produces pain, this process can not be ignored to the puzzlement that the patient brings.Pursue under the overall background of life Happiness current people, effectively reduce injection pain and be and reduce Medical fear, the raising people effective means of quality of life.Because, human from vaccinate at the beginning of the birth, just must begin in the face of the injection pain problem with the drug effect coexistence, therefore, the injection, puncture pain and the body injury that effectively reduce the patient are one of main directions of current medical device research.

At present, existing for studies show that of drug injection pain mechanism of production, the injection pain comes from syringe needle and thrusts the algogenic substance that skin discharges cell rupture.For induced pain mechanism, existing painless injection method mainly contains the injection of (1) micropin.Take microneedle array as representative, by reducing the mode of needle tubing diameter, effectively reduce skin injury area and algogenic substance and produce quantity, thereby realize the painless injection purpose.But the advantage that micropin needle tubing diameter is little has limited the effect of drug absorption, thereby its scope of application has been confined to efficient, a small amount of drug injection when reducing to keenly feel.(2) Needleless injection.Utilize high-pressure spray that drug particles is directly squeezed into subcutaneous a kind of painless injection technology.But, owing to realize that the required supplementary instrument of high-pressure spray is more, with high costs, so the popularization difficulty of Needleless injection is larger.(3) fast injection.Adopt inserting needle fast, push away medicine slow, pull out two fast one fast slow methods of pin, alleviate to a certain extent injection and keenly feel.But this method is subject to the impact of patient's subjective factors in actual applications, and different patient's results of use are different, and effect is unstable.(4) laser injection.Utilize laser ablation trace epidermis, make insulin directly enter human body, reach painless purpose.But its applicable medicine is single, still can not promote on a large scale.(5) meridians are massaged and Acupressure.As its name suggests, be a kind of technical skill that slows down injection pain by manipulation of massage.But its effect is very not remarkable, and and be not suitable for everyone, such as the anemia of pregnant woman, thus can only as subtract the pain supplementary means.(6) bionical needle injection.Be processed with spiral type, corrugated, zigzag or dimple-shaped biomimetic features on the needle tubing outer wall, by reducing the mode of the frictional resistance between syringe needle and skin histology, reduce in the injection process stimulation of teleneuron is reached the purpose that subtracts pain.But the method is only considered the frictional resistance of needle tubing part, does not relate to the drag reduction of tip portion.And the needle point penetration Resistance is generally 2-3 times of needle tubing frictional resistance, thus, the minimizing needle tubing frictional resistance that the penetration Resistance of minimizing needle point compares, meaning is more great.Therefore, the invention of our this time proposition is to reduce the syringe needle that the needle point of penetration Resistance has bionical form.

Summary of the invention

The object of the invention is to overcome above-mentioned many disadvantages and the deficiency of existing painless injection mode, provide a kind of needle point to have the syringe needle of bionical form.By the mode of change needle surface form, the frictional resistance in the minimizing drug injection piercing process between needle point and skin histology, thus reduce injection process to the stimulation of teleneuron, reach the purpose that reduces injection pain.

Above-mentioned purpose of the present invention is achieved through the following technical solutions, and accompanying drawings is as follows:

A kind of needle point has the syringe needle of bionical form, the biomimetic features that its needle point outside wall surface or pinpoint inclined plane have bionical form, and described bionical form is stripe-shaped, dimple-shaped or corrugated; Be divided into two kinds of macroscopic view, microcosmic by bionical form size; Be divided into two kinds of needle point outside wall surface, pinpoint inclined planes by bionical morphologic localization; Rectangular or the del of cross section of the bionical form of described stripe-shaped; The cross section of the bionical form of described dimple-shaped is circular arc; The cross section of described corrugated bionical form is corrugated.Described stripe-shaped and corrugated biomimetic features, its arragement direction and needle shaft are to vertical; Described dimple-shaped biomimetic features, the rectangular or rhombus of its arrangement mode on needle point.

Described biomimetic features being distributed as on needle point is whole or local.

When described biomimetic features is macroscopic form, the groove depth 0.01-0.05mm of striped form, groove width 0.01-0.10mm, spacing 0.02-0.10mm, the pit depth 0.01-0.05mm of pit form, diameter 0.01-0.10mm, spacing 0.02-0.10mm, the ripple's depth 0.01-0.05mm of ripple form, width 0.01-0.10mm, spacing 0.02-0.10mm.

When described biomimetic features is microscopic pattern, be etched or the partial depth 1-10nm that expects, width 1-10nm, spacing 1-20nm are removed in sandblast.

The processing method of macroscopic view biomimetic features form is laser ablation; The processing method of microcosmic biomimetic features form is sandblast or chemical etching.

A kind of needle point has the syringe needle of bionical form, and needle point outside wall surface or the pinpoint inclined plane of described syringe needle have biomimetic features; Be divided into stripe-shaped, dimple-shaped, corrugated three kinds according to bionical form; Be divided into two kinds of macroscopic view, microcosmic according to bionical shape size.

The present invention is the syringe needle that needle point has bionical form, can be used for the biological tissue puncture injections such as intravenous needle, intramuscular injection pin, blood taking needle, living body sampling pin, body fluid drainage needle, medical intervention apparatus punctures.Its clinical occupation mode, method are identical with the conventional syringe syringe needle, without the special operational instructions for use.

Technique effect of the present invention is:

This syringe needle reduces the frictional resistance between needle point and skin histology by needle point outside wall surface or pinpoint inclined plane processing biomimetic features form at the standard syringe syringe needle, reduces the purpose of pain when being implemented in injection or puncture.Usually, in injection, in the piercing process, pain mainly comes from neural perception to algogenic substance, and algogenic substance comes from syringe needle and the skin histology contact process destroyed histiocyte under the effect of frictional force between the two.The syringe needle that has bionical form on the needle point disclosed by the invention, can reduce the contact area of needle point and skin histology in injection, the piercing process, reduce frictional resistance between the two, thereby the histiocyte destructiveness is decreased, the algogenic substance that discharges reduces, and the injection pain reduces.

Description of drawings

Fig. 1 (a) is needle head structure sketch map of the present invention;

Fig. 1 (b) is the needle point partial enlarged drawing of Fig. 1 (a);

Fig. 1 (b1) is stripe-shaped on Fig. 1 (b) basis and corrugated pinpoint inclined plane biomimetic features partial enlarged drawing;

Fig. 1 (b2) is the dimple-shaped pinpoint inclined plane biomimetic features partial enlarged drawing on Fig. 1 (b) basis;

Fig. 1 (c) is the needle point partial enlarged drawing of Fig. 1 (a);

Fig. 1 (c1) is the stripe-shaped needle point outside wall surface biomimetic features partial enlarged drawing on Fig. 1 (c) basis;

Fig. 1 (c2) is the corrugated needle point outside wall surface biomimetic features partial enlarged drawing on Fig. 1 (c) basis;

Fig. 1 (c3) is the dimple-shaped needle point outside wall surface biomimetic features partial enlarged drawing on Fig. 1 (c) basis;

Fig. 1 (d1), (d2) are stripe-shaped biomimetic features cross section Local map;

Fig. 1 (d3) is dimple-shaped biomimetic features cross section Local map;

Fig. 1 (d4) is corrugated biomimetic features cross section Local map.

Fig. 2 is dimple-shaped biomimetic features distribution mode sketch map, wherein:

Fig. 2 (a) by the rectangular distribution;

Fig. 2 (b) presses rhombus and distributes.

Fig. 3 (a) is take the biomimetic features degree of depth, width, the spacing sketch map of cross section as zigzag striated structure as example;

Fig. 3 (a1) is take the biomimetic features degree of depth, width, the spacing sketch map (pinpoint inclined plane) of cross section as zigzag striated structure as example;

Fig. 3 (a2) is take the biomimetic features degree of depth, width, the spacing sketch map (needle point outside wall surface) of cross section as zigzag striated structure as example;

Fig. 3 (b) is the biomimetic features degree of depth, diameter, the spacing sketch map as an example of the dimple-shaped structure of distributed rectangular example;

Fig. 3 (b1) is the biomimetic features degree of depth, diameter, the spacing sketch map (pinpoint inclined plane) as an example of the dimple-shaped structure of distributed rectangular example;

Fig. 3 (b2) is the biomimetic features degree of depth, diameter, the spacing sketch map (needle point outside wall surface) as an example of the dimple-shaped structure of distributed rectangular example;

Fig. 3 (c) is the degree of depth, width, the spacing sketch map of corrugated biomimetic features;

Fig. 3 (c1) is the degree of depth, width, the spacing sketch map (pinpoint inclined plane) of corrugated biomimetic features;

Fig. 3 (c2) is the degree of depth, width, the spacing sketch map (needle point outside wall surface) of corrugated biomimetic features;

Fig. 4 is the application sketch map in other types injection, the puncture instrument.

In the accompanying drawing 1, the needle tubing Connection Block, 2, the needle tubing surface, 3, needle point, 4, the bionical form on the pinpoint inclined plane, 5, the range of work, 6, distributed rectangular, 7 rhombuses distribute, and 8, spacing, 9, width, 10, diameter, 11, the degree of depth, 12, sub-pin, 13, female pin, 14, bionic surface

The specific embodiment

Below in conjunction with the accompanying drawing example illustrated particular content of the present invention and embodiment are further specified.

A kind of needle point has the syringe needle of bionical form, is made of the biomimetic features on syringe needle and the needle point, and biomimetic features wherein is divided into two kinds of both macro and micros by size; Be divided into stripe-shaped, dimple-shaped, corrugated three kinds by shape; Opsition dependent is divided into two kinds of needle point outside wall surface and pinpoint inclined planes.

The size range of pinpoint inclined plane biomimetic features: during macroscopic form, the groove depth 0.01-0.05mm of striped form, groove width 0.01-0.10mm, spacing 0.02-0.10mm, the pit depth 0.01-0.05mm of pit form, diameter 0.01-0.10mm, spacing 0.02-0.10mm, the ripple's depth 0.01-0.05mm of ripple form, width 0.01-0.10mm, spacing 0.02-0.10mm; During microscopic pattern, be etched or the partial depth 1-10nm that expects, width 1-10nm, spacing 1-20nm are removed in sandblast.

The distribution of biomimetic features can occupy whole needle points, also can only be present in the part.

The present invention is the syringe needle that needle point has bionical form, on the medical interventional instruments such as the venoclysis needle that need use when can be applicable to the Chinese medicine injection of clinical treatment field, puncture sampling, intramuscular injection pin, blood taking needle, biopsy needle.Its clinical use is identical with the conventional syringe syringe needle, without the special operational instructions for use.

Characteristics of the present invention are the biomimetic features form on the needle point.Take the intramuscular injection pin as example, have biomimetic features in syringe needle needle point outside wall surface 3 or pinpoint inclined plane 4, bionical female area account for needle surface long-pending 30% in, its depression distributes and can consult Fig. 1 and Fig. 2.In the clinical use, because the effect of bionical shape depression on the needle point, reduce needle point and thrust real contact area in the process and between skin histology, make that histiocytic destructiveness descends in the process of thrusting, the algogenic substance that discharges reduces, and the stimulation of teleneuron is weakened.Syringe needle disclosed by the invention, its using method and conventional syringe syringe needle are as good as, and user is not had SOR, are subjected to the user because the syringe needle penetration Resistance reduces, and the pain that is subject to reduces.

Consult Fig. 4, the bionical form on the needle point can be used for venoclysis needle, biopsy male/female needle 12, injection, the Centesis instruments such as 13.Different according to the syringe needle model, its biomimetic features arrangement mode can suitably be adjusted, and is less than 30% but need the shared needle surface of the bionical recess of assurance to amass.Its painless principle is identical, all is by reducing the mode of the real contact area between syringe needle and skin histology, realizing subtracting the pain effect.

Macroscopic view biomimetic features form can be obtained by laser ablation; Microcosmic biomimetic features form can be obtained by sandblast or chemical etching.

Claims (6)

1. syringe needle that needle point has bionical form, the biomimetic features that its needle point outside wall surface or pinpoint inclined plane have bionical form is characterized in that:

Described bionical form is stripe-shaped, dimple-shaped or corrugated; Be divided into two kinds of macroscopic view, microcosmic by bionical form size; Be divided into two kinds of needle point outside wall surface, pinpoint inclined planes by bionical morphologic localization; Rectangular or the del of cross section of the bionical form of described stripe-shaped; The cross section of the bionical form of described dimple-shaped is circular arc; The cross section of described corrugated bionical form is corrugated.

2. the syringe needle that has bionical form according to claims 1 described a kind of needle point is characterized in that: described stripe-shaped and corrugated biomimetic features, and its arragement direction and needle shaft are to vertical; Described dimple-shaped biomimetic features, the rectangular or rhombus of its arrangement mode on needle point.

3. the syringe needle that has bionical form according to claims 1 or 2 described a kind of needle points is characterized in that: described biomimetic features being distributed as on needle point is whole or local.

4. the syringe needle that has bionical form according to claims 3 described a kind of needle points is characterized in that:

When described biomimetic features is macroscopic form, the groove depth 0.01-0.05mm of striped form, groove width 0.01-0.10mm, spacing 0.02-0.10mm, the pit depth 0.01-0.05mm of pit form, diameter 0.01-0.10mm, spacing 0.02-0.10mm, the ripple's depth 0.01-0.05mm of ripple form, width 0.01-0.10mm, spacing 0.02-0.10mm.

5. the syringe needle that has bionical form according to claims 3 described a kind of needle points is characterized in that:

When described biomimetic features is microscopic pattern, be etched or the partial depth 1-10nm that expects, width 1-10nm, spacing 1-20nm are removed in sandblast.

6. the syringe needle that has bionical form according to claims 3 described a kind of needle points is characterized in that:

The processing method of macroscopic view biomimetic features form is laser ablation; The processing method of microcosmic biomimetic features form is sandblast or chemical etching.

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