CN103040540A - Lavage device for animal - Google Patents
Lavage device for animal Download PDFInfo
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- CN103040540A CN103040540A CN2013100044912A CN201310004491A CN103040540A CN 103040540 A CN103040540 A CN 103040540A CN 2013100044912 A CN2013100044912 A CN 2013100044912A CN 201310004491 A CN201310004491 A CN 201310004491A CN 103040540 A CN103040540 A CN 103040540A
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- animal
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- tubular body
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- discharge bin
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Abstract
The invention relates to a lavage device for an animal. The lavage device comprises a cylinder (11), a tube (10) and a press piston (1). In a cylinder (11), a main gear (4) is connected with the press piston (1) through a driving connecting rod (3). When the press piston (1) is pressed by external force, a spring (2) is compressed, the press piston (1) moves downwards, and the driving connecting rod (3) moves downwards to drive the main gear (4) to rotate. A conveying belt (6) is arranged in the tube (10), a pinion (5) on the conveying belt (6) is meshed with the main gear (4), and when the main gear (4) rotates, the conveying belt (6) is driven to rotate by the pinion (5). A plurality of shift pieces (9) are arranged on the surface of the conveying belt (6) and move along with the conveying belt, so that materials can be fed into a stomach of an experiment animal through the tube (10) from a storage bin (8). The lavage device for the animal is simple to operate, large in drug feed and high in drug feed speed.
Description
Technical field
The present invention relates to a kind of irrigation stomach device, relate in particular to a kind of animal irrigation stomach device.
Background technology
At present, along with development biological and pharmaceutical technology, zoopery has become a kind of infrastest method of biology and medical science, and gastric infusion is one of peroral administration modal mode of laboratory animal, and it helps pharmacodynamics, pharmacology and the toxicologic research of some oral class medicine things.
Common irrigation stomach device is a kind of special hollow needle with standard syringe interface in the prior art, the syringe needle of this pin is different from ordinary syringe, for fear of needle point thrust animal trachea or damage digestive tract and and have hollow head such as sphere, the shank of part irrigation stomach device is bent to the camber that adapts with the pharyngeal of laboratory animal and esophagus feature.Application number is the irrigation stomach device that discloses a kind of laboratory animal in the utility application of 201120462178.X, comprises the parts that strut that the laboratory animal mouth can be strutted; Application number is to disclose a kind of animal irrigation stomach device that can the Real-Time Monitoring fluid temperature in 201220145316.6 the utility application, and it is by sensor and control circuit monitoring fluid temperature.
But these irrigation stomach devices are to extract medicine in syringe by the stretching injector handle, and then the pushing syringe handle pours into medicinal liquid the stomach of laboratory animal.This irrigation stomach device is only applicable to liquid medicine, can't be suitable for for some solid drugs.
For microcapsule, micropill, microsphere in some interior pharmaceutical preparatioies, enteric coated capsule particularly, entering intestinal at medicine just can dissolve, avoid on the one hand the medicine irritation gastric mucosa, the effect of possibility gastric acid can destroy medicines structure on the one hand, though their water solubles, if will carry out again gastric infusion after its dissolving, also might destroy preparation structure, will affect to a great extent the pharmacology pharmacodynamic research of medicine.Especially for microcapsule, micropill, microsphere, itself have the effect of slow controlled release and defencive function composition, only carry out administration with solid form, just can reach the experiment purposes such as its pharmacological effect of research and toxicity, obtain believable experimental data.
Application number is to disclose a kind of irrigation stomach device in 201010219220.5 the application for a patent for invention, can carry out to laboratory animal the gastric infusion of solid drugs, but its needle aperture is little, and the irrigation stomach device volume is little, injection speed is slow, the gavage time is long, has increased the misery of laboratory animal, and need to apply larger external force.
Summary of the invention
For above shortcomings in the prior art, one of technical problem to be solved by this invention provides a kind of animal irrigation stomach device.
The present invention seeks to be achieved through the following technical solutions:
A kind of animal irrigation stomach device comprises:
Material is delivered to the laboratory animal stomach via tubular body 10 from discharge bin 8.
Preferably,
A kind of animal irrigation stomach device comprises:
Press piston 1, link to each other with cylindrical body 11, press piston 1 one ends and be exposed at cylindrical body 11 outsides, be used for finger presses, the other end is fixed on the cylindrical body 11 with upper spring 2 by 2;
In cylindrical body 11, be provided with gear wheel 4 with the junction of tubular body 10, by drive link 3 with press piston 1 and link to each other, the junction point of drive link 3 and gear wheel 4 is at the non-home position of gear wheel 4;
In tubular body 10, be provided with a conveyer belt 6 along tubular body 10 axial directions, conveyer belt 6 has fast pulley 7 at the material outlet end of tubular body 10, at link pinion 5 is arranged, pinion 5 and gear wheel 4 engagements;
When pressing piston 1 and be subject to external force, spring 2 compressions, pressing piston 1 moves down, so that moving down, drive link 3 drives gear wheel 4 rotations, when gear wheel 4 rotated, the pinion 5 that is engaged with rotated, and conveyer belt 6 rotates under the drive of pinion 5, when plectrum 9 moves with conveyer belt 6, material is delivered to the laboratory animal stomach from discharge bin 8 via tubular body 10.
The quantity of described plectrum 9 is preferably 2-30.
Further,
Also have the latch bracket 12 corresponding with described spring 2 in the cylindrical body 11, spring 2 is fixed in the cylindrical body 11.
The cross section of described tubular body 10 is original shape, is hollow ball-shape as the front end of material outlet.Avoid scratching trachea or the damage digestive tract of laboratory animal, reduce in the gastric infusion process sense of discomfort of laboratory animal.
The material of tubular body is preferably the material of rubber-like, and certain pliability is arranged, in order to insert gastric along oral cavity and the esophagus of animal.
A side relative with discharge bin 8 is provided with the curved surface depression on the described cylindrical body 11, so that the hand-held described irrigation stomach device of experimental implementation person.
The length of described conveyer belt 6 is less than or equal to the length of tubular body 10.
The present invention compared with prior art has following advantage:
1. the irrigation stomach device of the present invention's design can be used for the gastric infusion of the solid drugs such as microcapsule, micropill, microsphere, need not medicine is dissolved, directly carry out gastric infusion with the preparation ortho states, can better simulate the administering mode of human body, obtain scientific and reasonable experimental data;
2. irrigation stomach device of the present invention aperture is larger, and volume is large, can heavy dose of administration, be particularly useful for the laboratory animals such as rat, new zealand rabbit, dog and monkey;
3. irrigation stomach device of the present invention is easy to use, and injection speed is fast, can slow down the sense of discomfort of laboratory animal.
Description of drawings
Fig. 1 is the structural representation that animal is used irrigation stomach device.
Fig. 2 is the partial enlarged drawing that animal is used irrigation stomach device gear wheel and pinion.
Description of reference numerals: 1, press piston; 2, spring; 3, drive link; 4, gear wheel; 5, pinion; 6, conveyer belt; 7, fast pulley; 8, discharge bin; 9, plectrum; 10, tubular body; 11, cylindrical body; 12, latch bracket; 13, charging aperture.
Fig. 3 is the top view that animal shown in Figure 1 is used irrigation stomach device.Define among the present invention, the cylindrical body 11 of irrigation stomach device is upward direction, and tubular body 10 1 sides are downward direction.
The specific embodiment
The invention will be further described below in conjunction with embodiment and Fig. 1, Fig. 2.
Embodiment
As shown in Figure 1, be the animal irrigation stomach device that a laboratory animal is used, comprise cylindrical body 11, tubular body 10 and press piston 1.
Press piston 1, link to each other with cylindrical body 11, press piston 1 one ends and be exposed at cylindrical body 11 outsides, be used for finger presses, the other end is fixed on the cylindrical body 11 with upper spring 2 and the latch bracket corresponding with spring by 2;
In cylindrical body 11, be provided with gear wheel 4 with the junction of tubular body 10, by drive link 3 with press piston 1 and link to each other, the junction point of drive link 3 and gear wheel 4 is in the non-home position (see figure 2) of gear wheel 4;
In tubular body 10, be provided with a conveyer belt 6 along tubular body 10 axial directions, conveyer belt 6 has fast pulley 7 at the material outlet end of tubular body 10, at link pinion 5 is arranged, pinion 5 and gear wheel 4 engagement (see figure 2)s;
When using this irrigation stomach device that experiment is carried out gastric infusion with new zealand rabbit, the material inlet of the materials such as microcapsule by discharge bin 8 entered discharge bin 8, hand-held cylindrical body 11, a side relative with discharge bin 8 is provided with the curved surface depression on the described cylindrical body 11, so that experimental implementation person's hand-held irrigation stomach device more easily; Tubular body 10 is inserted with the new zealand rabbit oral area from experiment.
Then press piston 1, when pressing piston 1 and be subject to external force, spring 2 compressions, pressing piston 1 moves down, so that drive link 3 moves down, because, driving gear wheel 4 at the non-home position of gear wheel 4 under the eccentric force effect, the junction point of drive link 3 and gear wheel 4 rotates; When gear wheel 4 rotated, the pinion 5 that is engaged with also rotated thereupon, and conveyer belt 6 rotates under the drive of pinion 5, when plectrum 9 moves with conveyer belt 6, the materials such as microcapsule was delivered to experiment with the new zealand rabbit stomach from discharge bin 8 via tubular body 10.
In the experiment, use the animal of present embodiment material directly can be carried out gastric infusion with the ortho states of microcapsule formulation with irrigation stomach device.The irrigation stomach device volume is large, can the larger dose administration, be well suited in the zooperies such as new zealand rabbit, dog and monkey, using.
The irrigation stomach device of present embodiment uses simply for experimental implementation person, and hand-held convenient, injection speed is fast, and in the gastric infusion process, experiment the significant discomfort sense all do not occur with new zealand rabbit.
Claims (7)
1. an animal irrigation stomach device is characterized in that, described animal comprises with irrigation stomach device:
Cylindrical body (11), cylindrical body (11) one sides are hollow discharge bin (8), discharge bin (8) has the opening as material inlet;
Tubular body (10) is the hollow elongated rod shape member that a front end can be inserted into the laboratory animal stomach, comprises as material outlet end and link, and link is connected with discharge bin (8);
Material is delivered to the laboratory animal stomach via tubular body (10) from discharge bin (8).
2. animal irrigation stomach device as claimed in claim 1 is characterized in that, described animal comprises with irrigation stomach device:
Cylindrical body (11), cylindrical body (11) one sides are hollow discharge bin (8), discharge bin (8) has the opening as material inlet;
Tubular body (10) is the hollow elongated rod shape member that a front end can be inserted into the laboratory animal stomach, comprises as material outlet end and link, and link is connected with discharge bin (8);
Press piston (1), link to each other with cylindrical body (11), press piston (1) one end and be exposed at cylindrical body (11) outside, be used for finger presses, the other end is fixed on the cylindrical body (11) with upper spring (2) by 2;
In cylindrical body (11), be provided with gear wheel (4) with the junction of tubular body (10), by drive link (3) with press piston (1) and link to each other, the junction point of drive link (3) and gear wheel (4) is at the non-home position of gear wheel (4);
In tubular body (10), be provided with a conveyer belt (6) along tubular body (10) axial direction, conveyer belt (6) has fast pulley (7) at the material outlet end of tubular body (10), at link pinion (5) is arranged, pinion (5) and gear wheel (4) engagement;
Conveyer belt (6) surface is provided with some plectrums (9);
When pressing piston (1) when being subject to external force, spring (2) compression, pressing piston (1) moves down, so that moving down, drive link (3) drives gear wheel (4) rotation, when gear wheel (4) rotated, the pinion that is engaged with (5) rotated, and conveyer belt (6) rotates under the drive of pinion (5), when plectrum (9) is mobile with conveyer belt (6), material is delivered to the laboratory animal stomach from discharge bin (8) via tubular body (10).
3. animal irrigation stomach device as claimed in claim 1, it is characterized in that: the quantity of described plectrum (9) is 2-30.
4. animal irrigation stomach device as claimed in claim 1 is characterized in that: also have the latch bracket (12) corresponding with described spring (2) in the cylindrical body (11), spring (2) is fixed in the cylindrical body (11).
5. animal irrigation stomach device as claimed in claim 1 is characterized in that: the cross section of described tubular body (10) is for circular, is hollow ball-shape as the front end of material outlet.
6. animal irrigation stomach device as claimed in claim 1, it is characterized in that: the upper side relative with discharge bin (8) of described cylindrical body (11) is provided with the curved surface depression, so that experimental implementation person hands described irrigation stomach device.
7. animal irrigation stomach device as claimed in claim 1, it is characterized in that: the length of described conveyer belt (6) is less than or equal to the length of tubular body (10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310004491.2A CN103040540B (en) | 2013-01-07 | 2013-01-07 | Lavage device for animal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310004491.2A CN103040540B (en) | 2013-01-07 | 2013-01-07 | Lavage device for animal |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103040540A true CN103040540A (en) | 2013-04-17 |
| CN103040540B CN103040540B (en) | 2015-01-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310004491.2A Active CN103040540B (en) | 2013-01-07 | 2013-01-07 | Lavage device for animal |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106308969A (en) * | 2016-08-23 | 2017-01-11 | 黄雁超 | Gavage recognizer and use method thereof |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101147702A (en) * | 2007-10-22 | 2008-03-26 | 施惠德洋行 | Needle cylinder type medicine feeding device |
| JP2009131629A (en) * | 2007-11-08 | 2009-06-18 | Ajinomoto Co Inc | Oral administration tool for small animal |
| CN101926691A (en) * | 2010-06-25 | 2010-12-29 | 杜冠华 | Intragastric administration device |
| CN201727605U (en) * | 2010-05-13 | 2011-02-02 | 马俊林 | Drencher for domestic animals |
| CN202051848U (en) * | 2011-03-19 | 2011-11-30 | 郝小静 | Novel medicine-feeding device |
| CN202136443U (en) * | 2011-06-23 | 2012-02-08 | 东北农业大学 | Livestock drencher |
| CN202143659U (en) * | 2011-06-16 | 2012-02-15 | 浙江省医学科学院 | Rat stomach perfusing and medicine applying device |
| CN203107329U (en) * | 2013-01-07 | 2013-08-07 | 上海市计划生育科学研究所 | Lavage apparatus for animals |
-
2013
- 2013-01-07 CN CN201310004491.2A patent/CN103040540B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101147702A (en) * | 2007-10-22 | 2008-03-26 | 施惠德洋行 | Needle cylinder type medicine feeding device |
| JP2009131629A (en) * | 2007-11-08 | 2009-06-18 | Ajinomoto Co Inc | Oral administration tool for small animal |
| CN201727605U (en) * | 2010-05-13 | 2011-02-02 | 马俊林 | Drencher for domestic animals |
| CN101926691A (en) * | 2010-06-25 | 2010-12-29 | 杜冠华 | Intragastric administration device |
| CN202051848U (en) * | 2011-03-19 | 2011-11-30 | 郝小静 | Novel medicine-feeding device |
| CN202143659U (en) * | 2011-06-16 | 2012-02-15 | 浙江省医学科学院 | Rat stomach perfusing and medicine applying device |
| CN202136443U (en) * | 2011-06-23 | 2012-02-08 | 东北农业大学 | Livestock drencher |
| CN203107329U (en) * | 2013-01-07 | 2013-08-07 | 上海市计划生育科学研究所 | Lavage apparatus for animals |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106308969A (en) * | 2016-08-23 | 2017-01-11 | 黄雁超 | Gavage recognizer and use method thereof |
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| CN103040540B (en) | 2015-01-07 |
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Address after: 200032 Shanghai Xuhui District Xietu Road No. 2140 Patentee after: Shanghai Institute of biomedical technology Address before: 200032 Shanghai Xuhui District Xietu Road No. 2140 Patentee before: SHANGHAI INSTITUTE OF PLANNED PARENTHOOD RESEARCH |
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