CN102670403A - Simple single-passage dosage process and dosage apparatus utilizing same - Google Patents

Simple single-passage dosage process and dosage apparatus utilizing same Download PDF

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CN102670403A
CN102670403A CN2012101662255A CN201210166225A CN102670403A CN 102670403 A CN102670403 A CN 102670403A CN 2012101662255 A CN2012101662255 A CN 2012101662255A CN 201210166225 A CN201210166225 A CN 201210166225A CN 102670403 A CN102670403 A CN 102670403A
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bottle
soft plastic
medicine
plastic liquid
liquid bottle
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董黎
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Lanzhou Wenhe Medical Device Research Development Co Ltd
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Lanzhou Wenhe Medical Device Research Development Co Ltd
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Priority to PCT/CN2012/079989 priority patent/WO2013023560A1/en
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Abstract

The invention provides a simple single-passage dosage process and a dosage apparatus utilizing the same. A closed single passage is reserved between a medicine bottle and a soft plastic liquid bottle. The soft plastic liquid bottle is disposed above the medicine bottle reversely, drive force is generated by squeezing the soft plastic liquid bottle, and liquid in the soft plastic liquid bottle is squeezed into the medicine bottle to dissolve medicinal powder. The medicine bottle is then disposed above the soft plastic liquid bottle reversely, and air in the soft plastic liquid bottle is injected into the medicine bottle by squeezing the soft plastic liquid bottle again, so that liquid medicine in the medicine bottle is sucked into the soft plastic liquid bottle. Accordingly, the dosage process of transferring medical powder in the medicine bottle into the soft plastic liquid bottle is completed. The dosage apparatus consists of a single-passage displacement needle. Holes at two sharp ends of the displacement needle are communicated with each other to form a passage. By the aid of the simple single-passage dosage process and the dosage apparatus utilizing the same, operation can be simplified, pollution probability is lowered, medicine waste is reduced, cost is lowered, and high market popularization is achieved.

Description

一种简易单通道配药方法及其配药器A simple single-channel dispensing method and dispensing device

技术领域 technical field

本发明属于医疗器械技术领域,具体涉及一种简易单通道配药方法及其配药器。  The invention belongs to the technical field of medical devices, and in particular relates to a simple single-channel dispensing method and a dispensing device. the

背景技术 Background technique

国内外现有医疗中对输入液体的配药方法,均是采用一次性注射器抽吸少量液体注入盛装粉针剂的药瓶中,待药粉充分溶解后,再用注射器回抽、注入液体瓶中。上述传统配药方法,存在药物浪费、过程繁琐、容易污染等不足。针对上述不足,本申请人曾公开了一种用于粉针剂的配药方法及其配药装置(申请号:201110231119.6,申请日:2011年08月12日),该配药方法有效克服了现有技术中采用注射器配药方法的不足,并适用于玻璃或其它各类液体瓶,但实现该配药方法须用专用蠕动泵驱动,同时配药装置含蠕动软管及连接嘴等,针对某些配药需求(如广泛使用的软塑料液体瓶)而言,结构相对比较复杂。为此,本申请人又于2012年03月15日成功研发了一种简易(双通道)配药方法及其配药装置(申请号:201210068276.4),无需专用蠕动泵驱动,省去了蠕动软管及连接嘴等,结构得以简化、成本得以降低。但该装置的置换针内设双通道,生产工艺还是略显复杂,相对一些常规低廉药物的配药而言,其生产成本仍较高,另外,其置换针横截面直径相对较大,配药穿刺瓶塞时损伤面积也相对较大,对瓶塞密封完整性会产生一定的影响。 The dispensing method to the input liquid in existing medical treatment both at home and abroad, all is to adopt disposable syringe to suck a small amount of liquid to inject in the medicine bottle of dress powder injection, after the medicine powder fully dissolves, draw back with syringe again, inject in the liquid bottle. The above-mentioned traditional dispensing method has disadvantages such as drug waste, cumbersome process, and easy pollution. In view of the above deficiencies, the applicant once disclosed a dispensing method for powder injection and its dispensing device (application number: 201110231119.6, application date: August 12, 2011). The dispensing method using syringes is not suitable for glass or other types of liquid bottles, but the realization of this dispensing method must be driven by a special peristaltic pump. At the same time, the dispensing device includes peristaltic hoses and connecting nozzles. For the soft plastic liquid bottle used), the structure is relatively complicated. For this reason, the applicant successfully developed a simple (dual-channel) dispensing method and its dispensing device on March 15, 2012 (application number: 201210068276.4), which does not require a dedicated peristaltic pump drive, eliminating the need for peristaltic hoses and The structure can be simplified and the cost can be reduced. However, the replacement needle of this device is equipped with dual channels, and the production process is still slightly complicated. Compared with the dispensing of some conventional cheap drugs, its production cost is still high. The damage area is also relatively large when corking, which will have a certain impact on the sealing integrity of the cork.

发明内容 Contents of the invention

本发明的目的在于针对某些配药需求(如广泛使用的常规药物)提供一种更简易的单通道配药方法,进一步满足临床配药的多样化需求。 The purpose of the present invention is to provide a simpler single-channel dispensing method for certain dispensing requirements (such as widely used conventional drugs), so as to further meet the diverse needs of clinical dispensing.

本发明的另一目的在于对某些配药需求(如广泛使用的常规药物)提供一种成本更低廉、结构更简易的配药器。 Another object of the present invention is to provide a dispensing device with lower cost and simpler structure for certain dispensing needs (such as widely used conventional medicines).

为了实现上述目的,本发明采取的技术方案为: In order to achieve the above object, the technical scheme that the present invention takes is:

一种简易单通道配药方法,建立药瓶与软塑料液体瓶之间密闭的单通道,将软塑料液体瓶倒置于药瓶的上方,利用挤压软塑料液体瓶产生驱动力,挤出软塑料液体瓶中的液体进入到药瓶中溶解药粉;再将药瓶倒置于软塑料液体瓶的上方,再次挤压软塑料液体瓶,将软塑料液体瓶中的空气注入药瓶中,回吸药瓶中的药液进入到软塑料液体瓶中;完成将药瓶中的药粉转移到软塑料液体瓶中的配药过程。 A simple single-channel dispensing method, which establishes a closed single-channel between the medicine bottle and the soft plastic liquid bottle, puts the soft plastic liquid bottle upside down on the top of the medicine bottle, squeezes the soft plastic liquid bottle to generate driving force, and extrudes the soft plastic The liquid in the liquid bottle enters the medicine bottle to dissolve the medicine powder; then put the medicine bottle upside down on the top of the soft plastic liquid bottle, squeeze the soft plastic liquid bottle again, inject the air in the soft plastic liquid bottle into the medicine bottle, and suck the medicine back The medicine liquid in the bottle enters into the soft plastic liquid bottle; completes the dispensing process of transferring the medicine powder in the medicine bottle to the soft plastic liquid bottle.

一种实现上述简易单通道配药方法的配药器,它由一单通道置换针构成,该置换针两端尖锐,两端的开孔贯通构成一通道。 A dispensing device for realizing the above-mentioned simple single-channel dispensing method, which is composed of a single-channel replacement needle, the two ends of the replacement needle are sharp, and the openings at both ends pass through to form a channel.

所述的置换针的腰部设限位凸环,限定置换针插入软塑料液体瓶的一端,其长度小于软塑料液体瓶液面与其瓶塞之间的间距;限定置换针插入药瓶的一端,其开孔设在紧邻药瓶的瓶塞处。 The waist of the replacement needle is provided with a position-limiting protruding ring, which limits the insertion of one end of the replacement needle into the soft plastic liquid bottle, and its length is less than the distance between the liquid surface of the soft plastic liquid bottle and its cork; the limit of the insertion of the replacement needle at one end of the medicine bottle, The opening is located adjacent to the stopper of the medicine bottle.

本发明提供的上述简易单通道配药方法及其配药器,与传统注射器配药方法相比,操作简单,有效避免了针头反复在空气中暴露和将病房不洁空气注入液体瓶情况发生;与本申请人曾提供的“一种简易(双通道)配药方法及其配药装置(申请号:201210068276.4)”相比,尽管配药效率略低一些,但其结构更趋简单、成本更趋低廉,且置换针内为单通道,直径和截面积大大缩小,配药穿刺瓶塞时损伤面积相应减小,对瓶塞密封完整性的影响相应降低。该配药器与本申请人研发的其他配药装置一起,能够更好地满足多样化临床配药的需求。 Compared with the traditional syringe dispensing method, the above-mentioned simple single-channel dispensing method and dispensing device provided by the present invention are simple to operate, and effectively avoid repeated exposure of needles in the air and injection of unclean air in the ward into liquid bottles; Compared with "a simple (dual-channel) dispensing method and its dispensing device (Application No.: 201210068276.4)" provided by people, although the dispensing efficiency is slightly lower, its structure is simpler, the cost is lower, and the replacement needle The inside is a single channel, the diameter and cross-sectional area are greatly reduced, the damage area is correspondingly reduced when dispensing and puncturing the bottle stopper, and the impact on the sealing integrity of the bottle stopper is correspondingly reduced. The dispensing device, together with other dispensing devices developed by the applicant, can better meet the needs of diverse clinical dispensing.

附图说明 Description of drawings

图1为传统配药方法示意图 Fig. 1 is the schematic diagram of traditional dispensing method

图2为本发明配药装置结构示意图 Fig. 2 is a structural schematic diagram of the dispensing device of the present invention

图3-1、图3-2、图4-1、图4-2分别为本发明配药方法顺序示意图 Figure 3-1, Figure 3-2, Figure 4-1, and Figure 4-2 are schematic diagrams of the sequence of the dispensing method of the present invention

图中:B-液体瓶;b-药瓶;Z-注射器;1-通道;2-置换针;3-药瓶端开孔;4-液体瓶端开孔;5-限位凸环。 In the figure: B-liquid bottle; b-medicine bottle; Z-syringe; 1-channel; 2-replacement needle; 3-opening at the end of the medicine bottle; 4-opening at the end of the liquid bottle;

具体实施方式 Detailed ways

图1为传统配药方法示意图。配液过程需先用注射器Z从液体瓶B中抽吸少量液体注入药瓶b中溶解药粉,待药粉溶解后,再用注射器Z从药瓶b中回抽溶解液注入到液体瓶B,完成配药。整个过程不仅复杂,而且高浓度粉针剂溶解液会在药瓶b和注射器Z中残留造成浪费,同时注射器Z针头反复暴露在空气中容易受到污染。 Fig. 1 is the schematic diagram of traditional dispensing method. The liquid preparation process needs to use syringe Z to draw a small amount of liquid from liquid bottle B and inject it into medicine bottle b to dissolve the medicine powder. After the medicine powder is dissolved, use syringe Z to draw back the solution from medicine bottle b and inject it into liquid bottle B. dispensing medicine. The whole process is not only complicated, but also the high-concentration powder injection solution will remain in the medicine bottle b and syringe Z, causing waste, and the needle of syringe Z is easily polluted by repeated exposure to the air.

图2为本发明配药装置结构示意图。本发明配药装置是由一单通道置换针2构成,该置换针2为一体式结构,两端尖锐,一端为插入软塑料液体瓶B端,设有液体瓶端开孔4;另一端为插入药瓶b端,设有药瓶端开孔3,两端的开孔3、4贯通构成一轴向通道。置换针2的腰部设有限位凸环5,限位凸环5与通道1垂直设置,限位凸环5用于限定置换针2插入软塑料液体瓶B的一端,其长度小于软塑料液体瓶B内液面与其瓶塞之间的间距;限定置换针2插入药瓶b的一端,其开孔3设在紧邻药瓶b的瓶塞处。 Fig. 2 is a schematic structural diagram of the dispensing device of the present invention. The dispensing device of the present invention is composed of a single-channel replacement needle 2, the replacement needle 2 is an integral structure, both ends are sharp, one end is inserted into the B end of the soft plastic liquid bottle, and a hole 4 is provided at the end of the liquid bottle; The b end of the medicine bottle is provided with an opening 3 at the end of the medicine bottle, and the openings 3 and 4 at both ends are connected to form an axial passage. The waist of the replacement needle 2 is provided with a limiting convex ring 5, which is vertically arranged with the channel 1, and the limiting convex ring 5 is used to limit the end of the replacement needle 2 inserted into the soft plastic liquid bottle B, and its length is shorter than that of the soft plastic liquid bottle The distance between the liquid surface in B and its bottle stopper; it is limited to the end where the replacement needle 2 is inserted into the medicine bottle b, and the opening 3 is located at the stopper of the medicine bottle b.

图3-1、图3-1、图4-1、图4-2为本发明配药方法顺序示意图。配药时,将置换针2的两端分别插入对应的软塑料液体瓶B和药瓶b中,使药瓶端开孔3位于药瓶b内,使液体瓶端开孔4位于软塑料液体瓶B内。如图3-1所示,先将药瓶b置于下方,软塑料液体瓶B倒置于药瓶b上方,使置换针2位于软塑料液体瓶B内的一端处于软塑料液体瓶B的液体中,挤压软塑料液体瓶B增大其内部压力,软塑料液体瓶B内的压力将大于药瓶b内的压力,软塑料液体瓶B中的液体经通道1挤进药瓶b中。如图3-2所示,当解除对软塑料液体瓶B挤压时,软塑料液体瓶B内的压力变小,先前被挤入液体加压的药瓶b内的压力大于软塑料液体瓶B内的压力,使得药瓶b中的空气经通道1注入软塑料液体瓶B中,至两个瓶中重新恢复压力平衡。同理,反复挤压、松弛软塑料液体瓶B,上述压力变化和液体、气体转移将会不断进行。当药瓶b中的药粉溶解后,在保持原连接状态不变的情况下,翻转软塑料液体瓶B和药瓶b,使药瓶b倒置在软塑料液体瓶B上方,软塑料液体瓶B瓶口向上。如图4-1所示,此时,插入软塑料液体瓶B内的置换针2的顶端处于软塑料液体瓶B内的空气中,挤压软塑料液体瓶B增大其内部压力,软塑料液体瓶B内压力大于药瓶b内压力,软塑料液体瓶B中的空气经通道1被挤进药瓶b中。如图4-2所示,当解除对软塑料液体瓶B挤压时,软塑料液体瓶B内压力变小,先前被挤入空气加压的药瓶b内的压力大于软塑料液体瓶B内的压力,两瓶之间产生压力差,在该压力差的作用下,药瓶b中的药液经通道1被回吸到软塑料液体瓶B中。同理,反复挤压、松弛软塑料液体瓶B,上述压力变化和液体、气体转移将会不断进行,由于药瓶端开孔3的位置低,且紧邻药瓶b瓶塞,使得药瓶b中的药液被最大限度排空,减少药液在药瓶b中的残留。 Fig. 3-1, Fig. 3-1, Fig. 4-1, Fig. 4-2 are schematic diagrams of the sequence of the dispensing method of the present invention. When dispensing medicine, insert the two ends of the replacement needle 2 into the corresponding soft plastic liquid bottle B and medicine bottle b respectively, so that the opening 3 at the end of the medicine bottle is located in the medicine bottle b, and the opening 4 at the end of the liquid bottle is located in the soft plastic liquid bottle inside B. As shown in Figure 3-1, first place the medicine bottle b at the bottom, and put the soft plastic liquid bottle B upside down on the top of the medicine bottle b, so that the end of the replacement needle 2 located in the soft plastic liquid bottle B is in the liquid of the soft plastic liquid bottle B , squeeze the soft plastic liquid bottle B to increase its internal pressure, the pressure in the soft plastic liquid bottle B will be greater than the pressure in the medicine bottle b, and the liquid in the soft plastic liquid bottle B is squeezed into the medicine bottle b through channel 1. As shown in Figure 3-2, when the squeeze on the soft plastic liquid bottle B is released, the pressure inside the soft plastic liquid bottle B becomes smaller, and the pressure in the previously squeezed liquid pressurized medicine bottle b is greater than that of the soft plastic liquid bottle The pressure in B makes the air in the medicine bottle b inject into the soft plastic liquid bottle B through channel 1, and restore the pressure balance in the two bottles. In the same way, by repeatedly extruding and relaxing the soft plastic liquid bottle B, the above-mentioned pressure change and liquid and gas transfer will continue. After the medicine powder in the medicine bottle b is dissolved, under the condition of keeping the original connection state unchanged, turn over the soft plastic liquid bottle B and the medicine bottle b, so that the medicine bottle b is upside down on the top of the soft plastic liquid bottle B, and the soft plastic liquid bottle B The mouth of the bottle is up. As shown in Figure 4-1, at this time, the tip of the replacement needle 2 inserted into the soft plastic liquid bottle B is in the air in the soft plastic liquid bottle B, squeezing the soft plastic liquid bottle B increases its internal pressure, and the soft plastic liquid bottle B The pressure in the liquid bottle B is greater than the pressure in the medicine bottle b, and the air in the soft plastic liquid bottle B is squeezed into the medicine bottle b through the channel 1. As shown in Figure 4-2, when the squeeze on the soft plastic liquid bottle B is released, the pressure inside the soft plastic liquid bottle B becomes smaller, and the pressure in the previously squeezed air-pressurized medicine bottle B is greater than that of the soft plastic liquid bottle B Under the action of the pressure difference, the liquid medicine in the medicine bottle b is sucked back into the soft plastic liquid bottle B through channel 1. Similarly, if the soft plastic liquid bottle B is repeatedly squeezed and loosened, the above-mentioned pressure change and liquid and gas transfer will continue. Since the opening 3 at the end of the medicine bottle is located at a low position and is close to the stopper of the medicine bottle b, the medicine bottle b The liquid medicine in the bottle b is emptied to the greatest extent, reducing the residue of the liquid medicine in the medicine bottle b.

本发明提供的配药方法及配药器,只需反复挤压软塑料液体瓶B即可完成配药过程,操作简单,其特别设计的药瓶端开孔位置尽可能地减少了药液在药瓶b中残留。该配药器与注射器配药方法相比,液体和空气的转移均是在两个无菌瓶之间进行,避免针头反复在空气中暴露和将病房不洁空气注入液体瓶B中;与申请人曾提供的“一种简易(双通道)配药方法及其配药装置(申请号:201210068276.4)”相比,尽管配药效率略低一些,但其结构更趋简单、成本更趋低廉,更具市场普及性。该配药器与本申请人研发的其他配药装置一起,能够更好地满足临床配药的多样化需求。 The dispensing method and dispensing device provided by the present invention can complete the dispensing process only by repeatedly squeezing the soft plastic liquid bottle B, and the operation is simple. Residues in. Compared with the syringe dispensing method, this dispensing device transfers liquid and air between two sterile bottles, avoiding repeated exposure of needles in the air and injecting unclean air in the ward into liquid bottle B; Compared with the "simple (dual-channel) dispensing method and its dispensing device (Application No.: 201210068276.4)", although the dispensing efficiency is slightly lower, its structure is simpler, the cost is lower, and it is more popular in the market . The dispensing device, together with other dispensing devices developed by the applicant, can better meet the diverse needs of clinical dispensing.

Claims (3)

1.一种简易单通道配药方法,其特征是:建立药瓶(b)与软塑料液体瓶(B)之间密闭的单通道,将软塑料液体瓶(B)倒置于药瓶(b)的上方,利用挤压软塑料液体瓶(B)产生驱动力,挤出软塑料液体瓶(B)中的液体进入到药瓶(b)中溶解药粉;再将药瓶(b)倒置于软塑料液体瓶(B)的上方,再次挤压软塑料液体瓶(B),将软塑料液体瓶(B)中的空气注入药瓶(b)中,回吸药瓶(b)中的药液进入到软塑料液体瓶(B)中;完成将药瓶(b)中的药粉转移到软塑料液体瓶(B)中的配药过程。 1. A simple single-channel dispensing method, characterized by: establishing a closed single-channel between the medicine bottle (b) and the soft plastic liquid bottle (B), and placing the soft plastic liquid bottle (B) upside down on the medicine bottle (b) above, squeeze the soft plastic liquid bottle (B) to generate the driving force, extrude the liquid in the soft plastic liquid bottle (B) into the medicine bottle (b) to dissolve the medicine powder; then put the medicine bottle (b) upside down on the soft Above the plastic liquid bottle (B), squeeze the soft plastic liquid bottle (B) again, inject the air in the soft plastic liquid bottle (B) into the medicine bottle (b), and suck back the medicine liquid in the medicine bottle (b) into the soft plastic liquid bottle (B); complete the dispensing process of transferring the powder in the medicine bottle (b) to the soft plastic liquid bottle (B). 2.一种实现如权利要求1所述简易单通道配药方法的配药器,其特征是:它由一单通道置换针(2)构成,该置换针(2)两端尖锐,两端的开孔(3、4)贯通构成一通道(1)。 2. A dispensing device for realizing the simple single-channel dispensing method as claimed in claim 1, characterized in that: it is composed of a single-channel replacement needle (2), the two ends of the replacement needle (2) are sharp, and the openings at both ends are (3, 4) connect to form a channel (1). 3. 根据权利要求2所述的配药器,其特征是:所述的置换针(2)的腰部设限位凸环(5),限定置换针(2)插入软塑料液体瓶(B)的一端,其长度小于软塑料液体瓶(B)内液面与其瓶塞之间的间距;限定置换针(2)插入药瓶(b)的一端,其开孔(3)设在紧邻药瓶(b)的瓶塞处。 3. The dispensing device according to claim 2, characterized in that: the waist of the replacement needle (2) is provided with a limiting convex ring (5) to limit the insertion of the replacement needle (2) into the soft plastic liquid bottle (B). One end, the length of which is less than the distance between the liquid level in the soft plastic liquid bottle (B) and its cork; the end where the replacement needle (2) is inserted into the medicine bottle (b) is limited, and the opening (3) is located adjacent to the medicine bottle ( b) at the cork.
CN2012101662255A 2011-08-12 2012-05-26 Simple single-passage dosage process and dosage apparatus utilizing same Pending CN102670403A (en)

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WO2013023560A1 (en) * 2011-08-12 2013-02-21 兰州汶河医疗器械研制开发有限公司 Dispensing method of powder for injection and dispensing device thereof
CN103156774A (en) * 2013-04-12 2013-06-19 冀中能源峰峰集团有限公司总医院 Suction type and handle type soluble drug doser
CN105125340A (en) * 2015-09-10 2015-12-09 成都华神生物技术有限责任公司 Medicine solution preparing device, using method thereof, medicine using device and using method thereof
CN105560057A (en) * 2015-12-22 2016-05-11 成都杰仕德科技有限公司 Powder injection bottle integrated type dispensing assembly and dispensing method
CN106361569A (en) * 2015-07-20 2017-02-01 中国医学科学院北京协和医院 Method for dispensing liquid by adopting liquid dispensing connector
CN108852834A (en) * 2018-08-03 2018-11-23 江苏苏云医疗器材有限公司 One kind is made up a prescription translator and dosage

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CN2472714Y (en) * 2001-03-20 2002-01-23 李转珍 Liquid adding device for powder medicine dissolution
CN201042544Y (en) * 2007-04-29 2008-04-02 柳东根 Device for powder preparation medicament dissolution and transfusion
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013023560A1 (en) * 2011-08-12 2013-02-21 兰州汶河医疗器械研制开发有限公司 Dispensing method of powder for injection and dispensing device thereof
CN103156774A (en) * 2013-04-12 2013-06-19 冀中能源峰峰集团有限公司总医院 Suction type and handle type soluble drug doser
CN106361569A (en) * 2015-07-20 2017-02-01 中国医学科学院北京协和医院 Method for dispensing liquid by adopting liquid dispensing connector
CN105125340A (en) * 2015-09-10 2015-12-09 成都华神生物技术有限责任公司 Medicine solution preparing device, using method thereof, medicine using device and using method thereof
CN105560057A (en) * 2015-12-22 2016-05-11 成都杰仕德科技有限公司 Powder injection bottle integrated type dispensing assembly and dispensing method
CN108852834A (en) * 2018-08-03 2018-11-23 江苏苏云医疗器材有限公司 One kind is made up a prescription translator and dosage

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Application publication date: 20120919