CN103040446A - Neural feedback training system and neural feedback training method on basis of optical brain imaging - Google Patents

Neural feedback training system and neural feedback training method on basis of optical brain imaging Download PDF

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CN103040446A
CN103040446A CN2012105933129A CN201210593312A CN103040446A CN 103040446 A CN103040446 A CN 103040446A CN 2012105933129 A CN2012105933129 A CN 2012105933129A CN 201210593312 A CN201210593312 A CN 201210593312A CN 103040446 A CN103040446 A CN 103040446A
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neural
training
neural activity
task
feedback
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朱朝喆
刘伟杰
段炼
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Beijing Normal University
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Beijing Normal University
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Abstract

The invention provides a neural feedback training system and a neural feedback training method on the basis of optical brain imaging. A trainee completes training tasks to achieve training purposes in the neural feedback training method. The neural feedback training method includes that neural activity data of the trainee are acquired by optical brain imaging equipment in a training task completion procedure; neural activity intensity indexes of a specific function system of the brain of the trainee are extracted from the neural activity data and are displayed to the trainee as feedback information; and the trainee adjusts training strategies according to the acquired feedback information, so that neural activities of the specific function system of the brain of the trainee are trained and are developed towards a target. The neural activity data of the trainee are acquired by the optical brain imaging equipment in the neural feedback training method. Compared with electroencephalogram and magnetic resonance imaging, the optical brain imaging is high in targeting, the optical brain imaging equipment is low in cost, and accordingly the neural feedback training system and the neural feedback training method are applicable to long-term neural feedback training.

Description

Neural feedback training system and neural feedback training method based on the imaging of optics brain
Technical field
The present invention relates to a kind of neural feedback training system based on the imaging of optics brain, relate to simultaneously a kind of neural feedback training method based on the imaging of optics brain.
Background technology
Neural feedback is movable by the cerebral nerve of online acquisition individuality and feeds back to himself, can independently regulate cerebral activity, reaches the purpose that changes its cognition and behavior.By specific brain function is intervened, thereby realize treatment and rehabilitation to the disease of brain patient, or the cognitive competence (such as study, memory etc.) of Healthy People is improved.
Researcher utilizes electroencephalogram (EEG) or functional mri (fMR I), the neural activity index in the target brain district of adjusting is wished in observation, and it is fed back to the trainee by passages such as audio visuals, thereby instruct the trainee to attempt this neural activity index in addition from main regulation.By the repetition training of certain hour, the trainee can grasp this autonomous regulating power.Because the neural activity in the brain district that is conditioned is related with the existence of specific knowledge function, therefore this long-term training can promote the improvement of corresponding cognitive competence, or some nerve is played therapeutical effect with mental sickness.The neural activity pattern that for example has bibliographical information to regulate visual cortex by neural feedback can significantly improve visual perception study sensitivity; Chronic pain patient then can ease the pain (specifically referring to Kazuhisa Shibata etal. by the neural activity that neural feedback is regulated Anterior cingulate cortex, Perceptual Learning Incepted by Decoded fMRI Neurofeedback Without Stimulus Presentation, SCIENCE, VOL.334 (2011) and deCharms etal., Control over brain activation and pain learned by using real-time functional MRI, PNAS, VOL.102, NO.51, (2005)).
The equipment that is used for the neural feedback training mainly concentrates on based on electroencephalogram or based on the neural feedback training system of functional mri.For example publication number is disclosed nervous feedback system based on real-time functional magnetic resonance signal in the Chinese invention patent application of CN101912255A, detect online the state of activation of brain by functional magnetic resonance signal, and Real-time Feedback is to trainee, by the cognitive activities level of repetition training regulation and control brain, improve or the corresponding cognitive function of recovery trainee.And for example publication number is the disclosed neural feedback instrument for training based on EEG signals that improves for the brain memory function in the Chinese invention patent application of CN102319067A, the scalp EEG signals that can utilize the cerebral activity process to collect, immediate status to memory is carried out detection by quantitative, and the brain wave rhythm ripple that will characterize the memory level is presented to the user, guides user is regulated the brain wave rhythm ripple consciously, reaches the purpose of improving the memory level.
Yet existing nervous feedback system still exists a lot of problems to wait to solve.For the nervous feedback system based on electroencephalogram, be difficult to definite location training brain district because the spatial resolution of electroencephalogram is extremely low, and the relation of electroencephalogram rhythm and pace of moving things composition and cognitive function also is still not clear, and therefore the targeting of training is poor, and its application is greatly limited.Although and overcome to a certain extent the deficiency of electroencephalogram system based on the nervous feedback system of nuclear magnetic resonance, but because MR imaging apparatus cost and use cost and costliness thereof, equipment volume is huge can not arbitrarily to be moved, can only be used for laboratory research, may not be used for clinical long-term treatment training and use.
Summary of the invention
Primary technical problem to be solved by this invention is to provide a kind of neural feedback training method based on the imaging of optics brain.
Another technical problem to be solved by this invention is to provide a kind of neural feedback training system based on the imaging of optics brain.
In order to reach above-mentioned goal of the invention, the present invention adopts following technical scheme:
A kind of neural feedback training method based on the imaging of optics brain is finished training mission by the trainee and is reached training objectives, comprises the steps:
(1) in described training mission complete process, gathers described trainee's neural activity data by optics brain imaging device; Go out the neural activity intensity index of brain specific function system from described neural activity extracting data; And the neural activity intensity index of described brain specific function system presented to described trainee as feedback information; Enter step (2);
(2) described trainee makes further training according to the described feedback information that obtains in the step (1); Enter step (3);
(3) process in the repeating step (1); Until described training mission finishes.
More preferably, in described step (1), extract HbO2 Oxyhemoglobin concentration, deoxyhemoglobin concentration, task mark and the timestamp information of current time by analyzing described neural activity data, and in conjunction with time started and concluding time of described training mission, calculate the neural activity intensity index of described brain specific function system.
More preferably, described training mission adopts chunk task design normal form, comprise the rest period and the task phase that hocket, in described step (1), the neural activity intensity index of described brain specific function system refers to the relative blood oxygen concentration value of described task phase with respect to the described rest period.
A kind of neural feedback training system be used to realizing above-mentioned neural feedback training method, comprise optics brain imaging device, CPU and display device, described optics brain imaging device is used for gathering trainee's neural activity data, and the described neural activity transfer of data that will collect is given described CPU, described CPU is used for the described neural activity data of combined training task analysis, obtain the neural activity intensity index of brain specific function system, and it is transferred to described display device, described display device is used for presenting feedback information to described trainee.
More preferably, described CPU comprises task module, acquisition module, decoder module and feedback module; Wherein, described task module is used for generating flow of task based on described training mission, and controls the implementation status of other modules; Described acquisition module is used for obtaining described neural activity data from described optics brain imaging device in real time, and with described neural activity transfer of data to described decoder module; Described decoder module is used for described neural activity data are carried out pretreatment, and extracts the neural activity intensity index of described brain specific function system; Described feedback module is used for the neural activity intensity index of described brain specific function system is fed back to described display device.
More preferably, described acquisition module is used for extracting from described optics brain imaging device in real time HbO2 Oxyhemoglobin concentration, deoxyhemoglobin concentration, task mark and the timestamp information of current time, and described HbO2 Oxyhemoglobin concentration, described deoxyhemoglobin concentration, described task mark and described timestamp information are transferred to described decoder module.
More preferably, described training mission comprises rest period and the task phase that hockets, and described task module is used for notifying described feedback module alternately to enter rest period or task phase; And described task module is used for notifying described decoder module with the time starting point of described rest period and described task phase and concluding time point.
More preferably, described decoder module is used for described neural activity data are carried out pretreatment; And from the result that pretreatment obtains, extract the average signal strength of the corresponding region of brain specific function system, again according to task time started information and task concluding time information from described task module, calculate the neural activity intensity index of described brain specific function system, the neural activity intensity index of described brain specific function system refers to the relative blood oxygen concentration value of described task phase with respect to the described rest period.
More preferably, the described feedback module neural activity intensity index that is used for described brain specific function system that described decoder module is obtained feeds back to described display device with the form of picture.
More preferably, described optics brain imaging device is the function near infrared spectrometer.
Neural feedback training system provided by the present invention and neural feedback training method, in training process, gather trainee's neural activity data by optics brain imaging device, and the neural activity intensity index of trainee's brain specific function system fed back to the trainee, thereby make the trainee regulate the training strategy according to the feedback information that obtains, so that the neural activity of its specific function system obtains training, develop to target.Wherein, optics brain imaging device utilizes the cerebral tissue hemoglobin to the difference characteristic of the near-infrared absorption rate of different wave length, and it is movable nondestructively to detect corticocerebral hematodinamics, and then the research cerebral nerve is movable.Compare with electroencephalogram, the imaging of optics brain have certain spatial resolution (1~3cm), can locate comparatively accurately the brain signal that observes, improved the targeting of training.Compare with nuclear magnetic resonance, optics brain imaging low price, equipment is light removable, can use at environment such as hospital, family, schools; The scanning circumstance safety and comfort can be carried out repeated multiple times measurement, are fit to the feedback training of the long-term Multiple-Scan of needs.
Description of drawings
Fig. 1 is that the neural feedback training system based on the imaging of optics brain provided by the present invention consists of sketch map;
Fig. 2 is in the embodiment of the invention, the runnable interface example of neural feedback training game;
Fig. 3 is in the embodiment of the invention, the experimental duties design example;
Fig. 4 is in the experimental duties shown in Figure 3, the relative HbO2 Oxyhemoglobin concentration sequential chart that No. 12 of trainee led;
Fig. 5 is in the experimental duties shown in Figure 3, the space activation graph of trainee's top auroral poles sheet;
Fig. 6 is in the experimental duties shown in Figure 3, the space activation graph of trainee's occipital lobe auroral poles sheet.
The specific embodiment
Below in conjunction with the drawings and specific embodiments summary of the invention of the present invention is elaborated.
Neural feedback training system based on optics brain imaging (fNIRS) provided by the present invention is finished training mission by the trainee and is realized training objectives.Finish in the process of training mission the trainee, the neural activity of specific function system in the optics brain imaging device captured in real time trainee brain, and the neural activity intensity of specific function system presented to the trainee in close friend's mode.The trainee regulates the training strategy according to the feedback information that obtains, so that the neural activity of its specific function system obtains training, thereby develops to target.The adjusting of the cognitive functions such as this neural feedback training method can be applied to move, language, emotion also can be used for the exercise rehabilitation training of patient with cerebral apoplexy.Certainly, should except having medical treatment value, also can be used for improving ordinary people's neural activity based on the neural feedback training method of optics brain imaging, and make ordinary people's neural activity obtain taking exercise.
Specifically, when using this neural feedback training system to train, realize through the following steps training process: step (1): in the training mission complete process, gather trainee's neural activity data by optics brain imaging device, go out the neural activity intensity index of brain specific function system from the neural activity extracting data, and the neural activity intensity index of brain specific function system presented to the trainee as feedback information, enter step (2); Step (2): the trainee makes further training according to the feedback information that obtains in the step (1), enters step (3); Step (3): the process in the repeating step (1), until training mission finishes.
Optics brain imaging device is a kind of equipment of non-intrusion type, utilizes the cerebral tissue hemoglobin to the difference characteristic of the near-infrared absorption rate of different wave length, and it is movable nondestructively to detect corticocerebral hematodinamics, and then the research cerebral nerve is movable.In above-mentioned steps (1), extract HbO2 Oxyhemoglobin concentration, deoxyhemoglobin concentration, task mark and the timestamp information of current time by analyzing the neural activity data, and the time started of combined training task and concluding time, calculate the neural activity intensity index of brain specific function system.In this neural feedback training method, the training activity comprises rest period and the task phase that hockets, and by the relative blood oxygen concentration value of calculation task stage with respect to the rest period, can obtain the neural activity intensity index of brain specific function system.More preferably, in this neural feedback training method, training mission adopts chunk task design normal form (block design), by adopting the fast task design of different groups, the neural feedback training that researcher can use the method that the trainee is correlated with easily.
The above briefly introduces the neural feedback training method based on the imaging of optics brain, and the below will introduce provided by the present invention based on the neural feedback training system of optics brain imaging and the process of utilizing this neural feedback training system to train in detail.Utilize this neural feedback training system to train, target is to feed back easily the neural activity intensity of himself to the trainee, makes it grasp regulate this movable ability, brings change in the behavior with this.
As shown in Figure 1, this neural feedback training system comprises optics brain imaging device 1, CPU 2 and display device 3.Wherein, optics brain imaging device 1 is used for gathering trainee's neural activity data, and with the neural activity transfer of data that collects to CPU 2, CPU 2 is analyzed neural activity data acquisition analysis result in conjunction with the training mission of carrying out, and analysis result transferred to display device 3, display device 3 is used for presenting feedback information to the trainee, and this feedback information refers to the neural activity intensity index of trainee's brain specific function system.
Wherein, optics brain imaging device 1 can be realized with the function near infrared spectrometer, for example can use the ETG-4000 functional near-infrared imaging device of Hitachi; CPU 2 can realize that with the host computer of operational system software display device 3 can be realized with LCD LCDs or other display.In CPU 2, comprise again task module 21, acquisition module 22, decoder module 23 and feedback module 24; Task module 21 is used for generating flow of task based on the chunk task design that main examination provides, and controls the implementation status of other modules; Acquisition module 22 is used for obtaining the neural activity data from optics brain imaging device 1 in real time, i.e. HbO2 Oxyhemoglobin concentration value and deoxyhemoglobin concentration value, and with the neural activity transfer of data to decoder module 23; Decoder module 23 is used for the neural activity data that acquisition module 22 obtains are carried out pretreatment, and extracts the neural activity intensity index of brain specific function system; The neural activity intensity index that feedback module 24 is used for decoder module 23 is obtained feeds back to display device 3, thereby presents to the trainee.
In this CPU 2, the specific implementation process of each functional module is as follows.Task module 21, based on the chunk task design parameter that main examination provides, rise time intervening sequence and task sequence, and safeguard an intervalometer.Intervalometer is pressed the time of time intervening sequence the inside as countdown.Complete when the intervalometer timing, revise current experiment according to task sequence and carry out condition, and notice feedback module 24 enters rest period or task phase; Meanwhile, notice decoder module 23, time starting point and the concluding time point of stage and task phase because the relative blood oxygen concentration value of decoder module 23 calculating need to be rested.Acquisition module 22, set up network connection and receive in real time the neural activity data with optics brain imaging device 1 by ICP/IP protocol, the neural activity data that receive are analyzed according to predefined data transmission format, extracted HbO2 Oxyhemoglobin concentration, deoxyhemoglobin concentration, task mark and the timestamp information of current time.Decoder module 23 receives the neural activity data from acquisition module 22, and it is carried out the preprocessing process that sliding window average filter, oxygenate subtract deoxyhemoglobin concentration; And from the result that pretreatment obtains, extract the average signal strength of institute of specific function system corresponding region, according to task time started information and task concluding time information from task module 21, calculate the relative blood oxygen concentration value of task phase with respect to the rest period again.This relative blood oxygen concentration value is the neural activity intensity index of brain specific function system.Feedback module 24, be divided into 2 step cycle and occur: the stage 1 is the rest period, presents the rest information, this moment the trainee what do not need to do body and mind relaxing; Stage 2 is task phase, and feedback module 24 receives the relative blood oxygen concentration value from decoder module 23, and presents to the trainee by the form close friends' such as game picture mode.At this moment, the trainee makes a response according to training method given in advance, thereby further controls the trend of game.For example, the trainee can send training guidance given in advance language as requested, by analyzing the optics brain imaging of trainee when the pronunciation practice, obtains the neural activity data of brain, further control game trend.
Here, take the neururgic embodiment that regulates trainee right side supplementary motor area (rSMA) by the neural feedback means as example, the implementation procedure of above-mentioned neural feedback training system is described.
Image shown in Figure 2 is the human-computer interaction interface that presents on the display device 3 among this embodiment, wherein, the zone at stone place is right side supplementary motor area corresponding zone in pickup area among the figure, the neural activity intensity that represents this neurological region with the height of stone, the height of stone is higher, represents that this regional neural activity intensity is stronger.From the picture that display device 3 presents, the trainee can clearly see the stone height of the neural activity intensity of the right side supplementary motor area that reflects oneself in training process, thereby recognizes the neural activity intensity that this is trained the zone.This human-computer interaction interface is comprised of two parts: a part is signal lights, and the left side when red represents to have a rest, and green light bright expression task in right side is carried out; Another part is stone, and the height of stone carries out input control by the neural activity intensity that collects.
In this training mission, the trainee heightens the stone height by motion imagination strategy, thereby tempers the corresponding specific neural neural activity ability of pickup area in the inactive situation of health.In this embodiment, the chunk task design normal form of training mission comprises 8 chunks as shown in Figure 3, and there are rest period and task phase two parts in each chunk inside, and wherein the rest period duration is 20 seconds, task phase duration 20 seconds.In this training mission, use the ETG-4000 of Hitachi optics brain imaging device to finish training, this optics brain imaging device disposes two 3 * 5 auroral poles sheet, is worn on respectively trainee's top and occipital lobe, wherein, comprise the right side supplementary motor area in the componental movement district that top covers.The neural activity intensity of the top institute corresponding region that collects by analysis can obtain the neural activity ability of right side supplementary motor area, and by contrast top and the occipital lobe neural activity intensity of corresponding region respectively, can determine the specificity of neural feedback training.
In the training mission complete process, the trainee is seeing the game picture on the display device 3, and bright when the danger signal lamp, the trainee is in resting state; Bright when greensignal light, trainee's setting in motion imagination is regulated the height of stone is raise as much as possible.
In task module 21, based on the chunk task design parameter that main examination provides, rise time intervening sequence.Set an intervalometer, reaction in per 20 seconds once moves 2*8=16 time altogether.When task module 21 collects the intervalometer reaction, just switch the state that carries out of training mission.If the physical training condition of switching is the rest period, then notify feedback module 24 to switch to the rest period; If the physical training condition of switching is task phase, then notify feedback module 24 to enter task phase, informed code module 23 recomputates baseline and begins and provides feedback information for feedback module 24 simultaneously.
Finish in the process of training mission the trainee, optics brain imaging device 2 is caught trainee's neural activity data.
Acquisition module 22 is set up network connection and is received in real time the neural activity data that optics brain imaging device 2 gathers with ETG-4000 by Transmission Control Protocol.Receive first 32 shaping data of 4 bytes, if value is 12, represent that then ensuing is the packet of a form such as table 1, wherein, in this packet, the blood oxygen concentration data are divided into two parts, and the first half content is HbO2 Oxyhemoglobin concentration, the latter half content is deoxyhemoglobin concentration, and each concentration value is the single precision floating datum of 8 bytes.Acquisition module 22 is analyzed the data that receive according to above-mentioned form, extract HbO2 Oxyhemoglobin concentration, deoxyhemoglobin concentration, task flagging and the timestamp information of current time, and above-mentioned data are sent to decoder module 23.
Size (byte) Content Data type
4 Package number Integer
4 Data package size Integer
Data package size-12 The blood oxygen concentration data Single precision floating datum
2 Data markers Integer
10 Timestamp Integer
Data format in table 1 packet
Decoder module 23 receives the data from acquisition module 22, and the line slip window average filter of going forward side by side, oxygenate subtract the preprocessing process of deoxyhemoglobin concentration.Wherein, the window long parameter of sliding window average filter is set as 1 second, and it is as follows that oxygenate subtracts the pretreatment formula of deoxyhemoglobin concentration:
α = Σx 2 Σ y 2 = std ( x ) std ( y )
x 0 = 1 2 ( x - αy )
y 0 = - 1 α x 0
Wherein, x closes the oxygen hemoglobin concentration, and y is deoxyhemoglobin concentration, and α is the ratio of the standard deviation of two kinds of hemoglobin concentration.x 0, y 0Respectively through pretreated oxygen hemoglobin concentration and the deoxyhemoglobin concentration of closing.
From the pretreatment result, extract the average signal strength of specific brain regions district (corresponding region of brain specific function system), according to calculating the blood oxygen concentration value at that time that obtains when have a rest finishing, calculate current blood oxygen concentration value relative blood oxygen concentration value relatively with it.This relative blood oxygen concentration value is the neural activity intensity of brain specific function system.In this embodiment, learn by dissecting the location in this specific brain regions district: supplementary motor area place, right side scalp is upper to be set to for locating between international 10-20 navigation system Cz and the C4 on the scalp.
Feedback module 24 communicates by Transmission Control Protocol with decoder module 23, is used for the analysis result of decoder module 23 is presented to the trainee.In this embodiment, feedback module 24 is presented to the trainee with the neural activity intensity index of specific function system with the picture of the stone game that independently suspends.Carry out the stage in task, it receives the result from decoder module 23, the data within 0~1 numerical range is converted into the height of stone.When the training stage of task module 21 switched to the rest period from task phase, stone dropped to ground naturally.
Can obtain two results in this training mission complete process: one is the time series chart of target brain district's activity, and whether be used for this activity of reflection relevant with training mission; Another is the space activation graph of brain imaging device viewing area, is used for determining the specificity of neural feedback debugging.
Fig. 4 is that objective function zone (that is, being arranged in the right side supplementary motor area of leading for No. 12) at the time series chart of experimentation, is used for the response activity process.Can see, this activity and task design have very strong dependency, strengthen at task phase (gray background) blood oxygen concentration, and rest period (white background) blood oxygen concentration weakens, thereby explanation, by neural feedback, the trainee can control the neural activity intensity of brain specific function system well.
Fig. 5 and Fig. 6 are respectively the space activation graphs of trainee two auroral poles sheet corresponding regions of wearing.Can see, activate more intense position on the space and all near target brain district, (see the space activation graph of top among Fig. 5), and with the irrelevant occipital lobe of task, mainly be visual zone, then do not demonstrate activation (seeing the space activation graph of Fig. 6 occipital lobe).From above-mentioned two width of cloth figure, can judge and use this neural feedback training system based on the imaging of optics brain to train, can regulate specifically the activity in target brain district.In finishing the process of this training mission, the trainee can regulate selectively by the motion imagination strategy activity in target brain district.This selectively adjusting can bring the value in clinical and the scientific research.For example, clinically, cerebral apoplexy patient is carried out exercise rehabilitation training, can combine actual motion and the training of brain motor function, efficiently solve Traditional Rehabilitation and train the drawback of only training muscle and not paying close attention to brain; In the scientific research, for researcher, by these means, can allow selectively the district's activity of tested brain, by observing its behavior change that brings, can provide the causalnexus of cerebration and behavior, for cognitive neuroscience research provides new thinking.
In sum, neural feedback training system and neural feedback training method based on the imaging of optics brain provided by the invention, wherein, the optics brain imaging device that relates to is a kind of equipment of non-intrusion type, utilize the cerebral tissue hemoglobin to the difference characteristic of the near-infrared absorption rate of different wave length, it is movable nondestructively to detect corticocerebral hematodinamics, and then the research cerebral nerve is movable.Compare with electroencephalogram, the imaging of optics brain have certain spatial resolution (1~3cm), can locate comparatively accurately the brain signal that observes, improved the targeting of training.Compare with nuclear magnetic resonance, optics brain imaging low price, equipment is light removable, can use at environment such as hospital, family, schools; The scanning circumstance safety and comfort can be carried out repeated multiple times measurement, are fit to the feedback training of the long-term Multiple-Scan of needs.
The above is described in detail the neural feedback training system based on the imaging of optics brain provided by the present invention and neural feedback training method.For one of ordinary skill in the art, any apparent change of under the prerequisite that does not deviate from connotation of the present invention it being done all will consist of infringement of patent right of the present invention, will bear corresponding legal responsibility.

Claims (10)

1. the neural feedback training method based on the imaging of optics brain is characterized in that comprising the steps:
(1) in the training mission complete process, gathers trainee's neural activity data by optics brain imaging device; Go out the neural activity intensity index of brain specific function system from described neural activity extracting data, and the neural activity intensity index of described brain specific function system is presented to described trainee as feedback information; Enter step (2);
(2) described trainee makes further training according to the described feedback information that obtains in the step (1); Enter step (3);
(3) process in the repeating step (1); Until described training mission finishes.
2. neural feedback training method as claimed in claim 1 is characterized in that:
In described step (1), extract HbO2 Oxyhemoglobin concentration, deoxyhemoglobin concentration, task mark and the timestamp information of current time by analyzing described neural activity data, and in conjunction with time started and concluding time of described training mission, calculate the neural activity intensity index of described brain specific function system.
3. neural feedback training method as claimed in claim 1 is characterized in that:
Described training mission adopts chunk task design normal form, comprise the rest period and the task phase that hocket, in described step (1), the neural activity intensity index of described brain specific function system refers to the relative blood oxygen concentration value of described task phase with respect to the described rest period.
4. neural feedback training system that is used for realizing neural feedback training method claimed in claim 1 is characterized in that:
Comprise optics brain imaging device, CPU and display device, wherein, described optics brain imaging device is used for gathering trainee's neural activity data, and the described neural activity transfer of data that will collect is given described CPU, described CPU is used for the described neural activity data of combined training task analysis, obtain the neural activity intensity index of brain specific function system, and it is transferred to described display device, described display device is used for presenting feedback information to described trainee.
5. neural feedback training system as claimed in claim 4 is characterized in that:
Described CPU comprises task module, acquisition module, decoder module and feedback module; Wherein, described task module is used for generating flow of task based on described training mission, and controls the implementation status of other modules; Described acquisition module is used for obtaining described neural activity data from described optics brain imaging device in real time, and with described neural activity transfer of data to described decoder module; Described decoder module is used for described neural activity data are carried out pretreatment, and extracts the neural activity intensity index of described brain specific function system; Described feedback module is used for the neural activity intensity index of described brain specific function system is fed back to described display device.
6. neural feedback training system as claimed in claim 5 is characterized in that:
Described acquisition module is used for extracting from described optics brain imaging device in real time HbO2 Oxyhemoglobin concentration, deoxyhemoglobin concentration, task mark and the timestamp information of current time, and described HbO2 Oxyhemoglobin concentration, described deoxyhemoglobin concentration, described task mark and described timestamp information are transferred to described decoder module.
7. neural feedback training system as claimed in claim 5 is characterized in that:
Described training mission comprises rest period and the task phase that hockets, and described task module is used for notifying described feedback module alternately to enter rest period or task phase; And described task module is used for notifying described decoder module with the time starting point of described rest period and described task phase and concluding time point.
8. neural feedback training system as claimed in claim 7 is characterized in that:
Described decoder module is used for described neural activity data are carried out pretreatment; And from the result that pretreatment obtains, extract the average signal strength of the corresponding region of brain specific function system, again according to task time started information and task concluding time information from described task module, calculate the neural activity intensity index of described brain specific function system, the neural activity intensity index of described brain specific function system refers to the relative blood oxygen concentration value of described task phase with respect to the described rest period.
9. neural feedback training system as claimed in claim 7 is characterized in that:
The neural activity intensity index that described feedback module is used for described brain specific function system that described decoder module is obtained feeds back to described display device with the form of picture.
10. neural feedback training system as claimed in claim 4 is characterized in that:
Described optics brain imaging device is the function near infrared spectrometer.
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