CN103030944A - Degradable material for tubal extraction plate and manufacturing method - Google Patents
Degradable material for tubal extraction plate and manufacturing method Download PDFInfo
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- CN103030944A CN103030944A CN2011102934661A CN201110293466A CN103030944A CN 103030944 A CN103030944 A CN 103030944A CN 2011102934661 A CN2011102934661 A CN 2011102934661A CN 201110293466 A CN201110293466 A CN 201110293466A CN 103030944 A CN103030944 A CN 103030944A
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- degradable
- tubal
- plate
- uterine tube
- extraction plate
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- Injection Moulding Of Plastics Or The Like (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Materials For Medical Uses (AREA)
- Biological Depolymerization Polymers (AREA)
Abstract
The present invention provides a degradable material for tubal extraction plates and a manufacturing method. The degradable material is prepared by polymer main ingredient of a degradable substrate and an enhancer. The injection molding process includes that: a feed inlet is of 150-165 DEG C, a compression segment is of 160-170 DEG C, a metering section is of 160-175 DEG C, a nozzle is of 165-175 DEG C, the mold temperature is 20-45 DEG C, the injection pressure is 45-85 Mpa, the injection time is 45-58 seconds, the dwell time is 0 sec, and the screw speed is 180 rpm. The performances of the degradable tubal extraction plate are in line with the requirements of national industry standard YY/T 0181-1994. The degradable tubal extraction plate can completely replace the metal tubal extraction plate. The waste degradable tubal extraction plate does not need incineration, and can completely degrade by landfilling in the natural environment. The degradable tubal extraction plate is especially suitable for disposable use, and helps to prevent iatrogenic disease cross-infection and achieve environmental-protection and energy-saving purposes.
Description
Technical field
The invention belongs to environmental protection and energy saving degradable disponsable medical instruments field, specifically a kind of uterine tube extracts plate with degradation material and method for making.
Background technology
Uterine tube extracts plate, extracts uterine tube when being mainly used in Ligation of female fallopian tubes clinically and uses.At present, it all is to make of stainless steel and other metal materials that uterine tube extracts plate, reuses and easily causes cross infection of disease, and use patient can feel the defective such as very ice-cold in the time in winter.For this reason, research and development degradation type disposable uterine tube extracts plate, can not only avoid the metal uterine tube to extract plate and reuse to stop the nosocomial disease cross infection, and many advantages that its degraded base material poly(lactic acid) has good biocompatibility will progressively substitute the medicine equipments such as stainless steel.But at home and abroad there is no about research and the report of uterine tube extraction plate with degradation material and method for making up to now.
Summary of the invention
First purpose of the present invention provides the uterine tube of making of degradation material and extracts plate.
Second purpose of the present invention provides uterine tube and extracts the method for making that plate is used degradation material.
Degraded type uterine tube of the present invention extracts plate, is made of the degradable base material, and its composition and weight proportion are:
100 parts of degradable macromolecule major ingredients, toughener 6-20 part;
Described polymer major ingredient is: poly(lactic acid) (PLA);
Described toughener is: EMFORCE BIO, Concha rapanae thomasianae powder or their blend.
The invention provides by degradable material and make the method for making that uterine tube extracts plate, step and condition are as follows:
The first step: the base material that proportioning is good, send in the homogenizer, rotating speed 600-800 rev/min, mixed 5-8 minute, make uniform base material or base material compound;
Second step: base material or base material compound that the first step is made; respectively under 50-80 ℃; vacuum-drying 3-8 hour, to send in the single screw extrusion machine, temperature is controlled at: feeding section 65-90 ℃; batch mixing segment 80-125 ℃; fluxing zone 125-180 ℃, head 100-175 ℃, screw speed 35-65 rev/min; after the dicing machine pelletizing, make respectively the pellet of above-mentioned base material.
The 3rd step: with above-mentioned base material pellet, under 50-60 ℃, vacuum-drying 4-6 hour, stand-by;
The 4th step: the pellet with above-mentioned oven dry, join injection moulding machine, be used for making the injection moulding that the degraded type uterine tube extracts plate;
Barrel temperature is set as: opening for feed 150-165 ℃, and compression section 160-170 ℃, metering zone 160-175 ℃, nozzle 165-175 ℃;
Die temperature is: 20-45 ℃;
Injection pressure is: 45-85Mpa;
Injection time is: 45-58 second;
Dwell time is: 0 second;
Screw speed is: 180 rev/mins;
Through after the injection moulding, the uterine tube that just can be made into degradable all size, model extracts plate.
Table 1 has provided uterine tube and has extracted the used biological degradation base material prescription of plate.
Table 1
The 5th step: encapsulation sterilization: will make complete degraded type uterine tube extraction plate and carry out small packages, middle packing and large packing by the requirement of disposable medical instrument, then carry out the sterilization of oxyethane or Co 60, and the sale of resolving and can dispatch from the factory after the assay was approved.
Beneficial effect: it is that material of main part is formulated with corresponding subsidiary material that degraded type uterine tube provided by the invention extracts the base materials employed preferred poly(lactic acid) of plate.Poly(lactic acid) (PLA) is to can be used for one of degradable polymer material of human body through the only a few that FDA ratifies, has good biocompatibility, suit very much to be used for making the degraded type uterine tube and extract the disposable medical instruments such as plate, it is fast that this degraded type uterine tube extracts the plate degradation speed, safe and applicable, and the present invention selects take EMFORCE BIO or Concha rapanae thomasianae powder as auxiliary material, all belongs to filling material utilized for environment protection, and compatibility rationally, effectively.The most important thing is that in addition the preparation technology that biodegradation type uterine tube provided by the invention extracts plate is detailed rationally, its indices meets national sector standard " YY/T 0181-1994 uterine tube extracts plate ", tool value for clinical application.
Embodiment
The prescription that following examples adopt is the prescription of above-mentioned table 1.
The degraded type uterine tube that embodiment 1 is made by degradable material extracts the injection molding forming method of plate:
The first step, vacuum-drying: will fill a prescription 1 or 2 the degradable base material pellet of filling a prescription, under 50-60 ℃, vacuum-drying 4-6 hour, stand-by;
Second step, injection moulding: the prescription 1 that will dry or 2 the degradable base material pellet of filling a prescription join in the injection moulding machine hopper, are used for making the injection moulding that the degraded type uterine tube extracts plate;
Barrel temperature is set as: opening for feed 150-165 ℃, and compression section 160-170 ℃, metering zone 160-175 ℃, nozzle 165-175 ℃;
Die temperature is: 20-45 ℃;
Injection pressure is: 45-85Mpa;
Injection time is: 45-58 second;
Dwell time is: 0 second;
Screw speed is: 180 rev/mins;
Obtain adopting prescription 1 or the degraded type uterine tube of 2 the degradable base material of filling a prescription extracts plate.
Above-described embodiment extracts plate to the biodegradation type uterine tube and is described in detail, its preparation technology is detailed rationally, and production cost is lower, therefore, degraded type uterine tube of the present invention extracts the suitable especially disposable use of plate, have good value for clinical application, can not only avoid the purpose of nosocomial disease cross infection, and environmental protection and energy saving.
Claims (2)
1. a uterine tube extracts plate with degradation material and method for making, it is characterized in that its degradation material is comprised of following composition and weight proportion:
100 parts of degradable macromolecule major ingredients, toughener 6-20 part;
Described polymer major ingredient is: poly(lactic acid) (PLA);
Described toughener is: EMFORCE BIO, Concha rapanae thomasianae powder or their blend.
2. extract plate with degradation material and method for making according to uterine tube as claimed in claim 1, it is characterized in that the step of its method for making and condition are as follows:
The first step, vacuum-drying: will extract for uterine tube the degradable base material pellet of plate, under 50-60 ℃, vacuum-drying 4-6 hour, stand-by;
Second step, injection moulding: above-mentioned oven dry is used for making the degradable base material pellet that the degraded type uterine tube extracts plate, joins injection moulding machine, be used for making the injection moulding that the degraded type uterine tube extracts plate;
Barrel temperature is set as: opening for feed 150-165 ℃, and compression section 160-170 ℃, metering zone 160-175 ℃, nozzle 165-175 ℃;
Die temperature is: 20-45 ℃;
Injection pressure is: 45-85Mpa;
Injection time is: 45-58 second;
Dwell time is: 0 second;
Screw speed is: 180 rev/mins;
The 3rd step, wrapped product, and carry out ethylene oxide sterilizing, parsing, through dispatching from the factory after the assay was approved.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110293466.1A CN103030944B (en) | 2011-09-29 | 2011-09-29 | Fallopian tube extracts plate degradation material and method for making |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110293466.1A CN103030944B (en) | 2011-09-29 | 2011-09-29 | Fallopian tube extracts plate degradation material and method for making |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103030944A true CN103030944A (en) | 2013-04-10 |
| CN103030944B CN103030944B (en) | 2016-06-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201110293466.1A Active CN103030944B (en) | 2011-09-29 | 2011-09-29 | Fallopian tube extracts plate degradation material and method for making |
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Citations (5)
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| US20050136259A1 (en) * | 2002-11-26 | 2005-06-23 | Mohanty Amar K. | Environmentally friendly polylactide-based composite formulations |
| CN101152588A (en) * | 2007-10-30 | 2008-04-02 | 中国科学院长春应用化学研究所 | Degradation type disposable syringe and method of producing the same |
| CN101468215A (en) * | 2007-12-29 | 2009-07-01 | 上海林静医疗器械有限公司 | Technique for producing degradable medical apparatus |
| CN101506278A (en) * | 2006-08-31 | 2009-08-12 | 金伯利-克拉克环球有限公司 | Highly breathable biodegradable films |
| CN101918485A (en) * | 2007-12-17 | 2010-12-15 | 密执安特种矿石公司 | Surface treated inorganic particle additive for increasing the toughness of polymers |
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2011
- 2011-09-29 CN CN201110293466.1A patent/CN103030944B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050136259A1 (en) * | 2002-11-26 | 2005-06-23 | Mohanty Amar K. | Environmentally friendly polylactide-based composite formulations |
| CN101506278A (en) * | 2006-08-31 | 2009-08-12 | 金伯利-克拉克环球有限公司 | Highly breathable biodegradable films |
| CN101152588A (en) * | 2007-10-30 | 2008-04-02 | 中国科学院长春应用化学研究所 | Degradation type disposable syringe and method of producing the same |
| CN101918485A (en) * | 2007-12-17 | 2010-12-15 | 密执安特种矿石公司 | Surface treated inorganic particle additive for increasing the toughness of polymers |
| CN101468215A (en) * | 2007-12-29 | 2009-07-01 | 上海林静医疗器械有限公司 | Technique for producing degradable medical apparatus |
Non-Patent Citations (4)
| Title |
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| 周凯等: "《碳酸钙填充聚乳酸复合材料的制备和性能研究》", 《中国塑料》, vol. 23, no. 6, 26 June 2009 (2009-06-26) * |
| 郝学安等: "《现代医院感染控制与实用消毒技术》", 31 July 2009, article "《第二十三章 低温灭菌技术的应用》", pages: 410-412 * |
| 韩跃新等: "《矿物材料》", 31 May 2006, article "《第6章 纳米矿物粉体材料》", pages: 292-293 * |
| 黄进等: "《生物质化工与生物质材料》", 31 August 2009, article "《第7章 聚乳酸合成工艺及应用》", pages: 184-185 * |
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| CN103030944B (en) | 2016-06-08 |
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Effective date of registration: 20181008 Address after: 224200 Jiangsu Dongtai machinery and Electronics Industrial Park 3 Jinfeng Road Patentee after: Jiangsu Aobo gold Pharmaceutical Technology Co. Ltd. Address before: 201600 No. 37, Yu Jia Road, Songjiang District, Shanghai. Patentee before: Shanghai Linjing Medical Equipment Co., Ltd. |