CN103028166A - Environment-friendly and energy-saving biodegradable type disposable infusion device thrusting needle and preparation method thereof - Google Patents
Environment-friendly and energy-saving biodegradable type disposable infusion device thrusting needle and preparation method thereof Download PDFInfo
- Publication number
- CN103028166A CN103028166A CN2011102935895A CN201110293589A CN103028166A CN 103028166 A CN103028166 A CN 103028166A CN 2011102935895 A CN2011102935895 A CN 2011102935895A CN 201110293589 A CN201110293589 A CN 201110293589A CN 103028166 A CN103028166 A CN 103028166A
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- China
- Prior art keywords
- type disposable
- contact pin
- transfusion device
- injection
- device contact
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000001802 infusion Methods 0.000 title abstract description 5
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000000463 material Substances 0.000 claims abstract description 21
- 238000002347 injection Methods 0.000 claims abstract description 19
- 239000007924 injection Substances 0.000 claims abstract description 19
- 230000006835 compression Effects 0.000 claims abstract description 4
- 238000007906 compression Methods 0.000 claims abstract description 4
- 230000015556 catabolic process Effects 0.000 claims description 20
- 238000006731 degradation reaction Methods 0.000 claims description 20
- 230000007613 environmental effect Effects 0.000 claims description 19
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 8
- 239000008188 pellet Substances 0.000 claims description 7
- 239000012744 reinforcing agent Substances 0.000 claims description 6
- 238000001291 vacuum drying Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 239000004615 ingredient Substances 0.000 claims description 4
- 229920002521 macromolecule Polymers 0.000 claims description 4
- 239000004626 polylactic acid Substances 0.000 claims description 4
- 238000001746 injection moulding Methods 0.000 abstract description 2
- 239000003623 enhancer Substances 0.000 abstract 1
- 239000002075 main ingredient Substances 0.000 abstract 1
- HGUFODBRKLSHSI-UHFFFAOYSA-N 2,3,7,8-tetrachloro-dibenzo-p-dioxin Chemical compound O1C2=CC(Cl)=C(Cl)C=C2OC2=C1C=C(Cl)C(Cl)=C2 HGUFODBRKLSHSI-UHFFFAOYSA-N 0.000 description 6
- 239000004033 plastic Substances 0.000 description 5
- 229920003023 plastic Polymers 0.000 description 5
- 230000000711 cancerogenic effect Effects 0.000 description 3
- 231100000357 carcinogen Toxicity 0.000 description 3
- 239000003183 carcinogenic agent Substances 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 238000004134 energy conservation Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000003208 petroleum Substances 0.000 description 2
- 230000007096 poisonous effect Effects 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 241000235388 Mucorales Species 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000006065 biodegradation reaction Methods 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 229920006237 degradable polymer Polymers 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002146 exchange transfusion Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000005453 pelletization Methods 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
Landscapes
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Injection Moulding Of Plastics Or The Like (AREA)
Abstract
The invention provides an environment-friendly and energy-saving biodegradable type disposable infusion device thrusting needle and a preparation method thereof. The environment-friendly and energy-saving biodegradable type disposable infusion device thrusting needle is formed by proportioning biodegradable macromolecular main ingredients and enhancers of biodegradable base materials. The injection molding process includes that the temperature of a feed inlet is 145-160 DEG C, the temperature of a compression section is 155-165 DEG C, the temperature of a metering section is 160-175 DEG C, and the temperature of a nozzle is 165-175 DEG C; the temperature of a mould is 10-20 DEG C; the injection pressure is 50-80 Mpa; the injection period is 41-52 seconds; the dwell time is 0 second; and the screw speed is 180 turns per minute. Thus, the environment-friendly and energy-saving biodegradable type disposable infusion device thrusting needle can be manufactured, the thrusting needle does not need to be incinerated after being discarded and can be absolutely biodegraded in the natural environment through landfill, and therefore the purposes of saving energy and protecting environment and human health are achieved.
Description
Technical field
The present invention relates to the technical field of bioengineering of medical apparatus and instruments, particularly relate to a kind of environmental protection and energy saving degradation type disposable transfusion device contact pin and method for making.
Background technology
" disposable transfusion device contact pin ", wherein an end is connected with the tube for transfusion of transfusion device, the other end is used for inserting in the pipe of transfusion bag, playing infusion channel connects, once property use transfusion device (straight hole is moulded contact pin) commonly used, disposable use blood exchange transfusion set (side opening is moulded contact pin), for example the patent No. is 01256294.7 " the bottle contact pin in the disposable transfusion device ", existing " disposable transfusion device contact pin ", make of nondegradable petroleum-based plastics such as ABS, but the clinical practice through decades proves, plastics disposable transfusion device contact pin needs by concentrating burning disposal after having use, plastics can produce a large amount of black smokes when burning, can discharge hydrogen chloride simultaneously, poisonous and the carcinogen such as dioxin, well-known plastics can produce a large amount of black smokes when burning, can discharge simultaneously the poisonous and carcinogen such as " dioxin " is suspended in the air, severe contamination environment, the toxicity of " dioxin " is very large, 900 times of arsenicum, the title that " poison in century " arranged, because " dioxin " is highly stable, hard degradation in environment, be difficult to discharge after entering human body, in human body, accumulate, only can get more and more, dioxin has strong carcinogenecity, and can cause deformity, all can cause damage to immunologic function and the reproduction merit of human body, IARC has classified dioxin as human one-level carcinogen, threatens human health.For this reason, research and development degradation type disposable transfusion device contact pin and method for making, burning disposal after not only having avoided using; environmental contamination reduction, to protect mankind is healthy, and has saved the energy; especially added pure halobiontic oyster shell powder, not only environmental protection but also energy-conservation, and reduced manufacturing cost.But up to now, at home and abroad there is no research and report about environmental protection and energy saving degradation type disposable transfusion device contact pin and method for making.
Summary of the invention
First purpose of the present invention provides environmental protection and energy saving degradation type disposable transfusion device contact pin.
Second purpose of the present invention provides environmental protection and energy saving degradation type disposable transfusion device contact pin and method for making.
Environmental protection and energy saving degradation type disposable transfusion device contact pin of the present invention, it is characterized in that: described disposable transfusion device contact pin is made of the degradable base material, and its composition and weight proportion are:
100 parts of degradable macromolecule major ingredients, reinforcing agent 15-23 part;
Described macromolecule major ingredient is: polylactic acid (PLA);
Described reinforcing agent is: EMFORCE BIO, oyster shell powder or their mixture;
Described oyster shell powder is 100-300 purpose oyster shell powder.
The invention provides the method for making of environmental protection and energy saving degradation type disposable transfusion device contact pin, step and condition are as follows:
The first step: the base material that proportioning is good, send in the homogenizer, rotating speed 600-800 rev/min, mixed 5-8 minute, make uniform base material or base material compound;
Second step: base material or base material compound that the first step is made; respectively under 50-65 ℃; vacuum drying 3-8 hour, to send in the single screw extrusion machine, temperature is controlled at: feeding section 65-90 ℃; batch mixing segment 80-125 ℃; fluxing zone 125-170 ℃, head 110-175 ℃, screw speed 35-90 rev/min; after the pelleter pelletizing, make respectively the pellet of above-mentioned base material.
The 3rd step: with above-mentioned base material pellet, under 50-60 ℃, vacuum drying 2-6 hour, stand-by;
The 4th step: with the pellet of above-mentioned oven dry, join in the injection machine hopper, carry out injection mo(u)lding by various types, all size of environmental protection and energy saving degradation type disposable transfusion device contact pin;
Barrel temperature is set as: charging aperture 145-160 ℃, and compression section 155-165 ℃, metering section 160-175 ℃, nozzle 165-175 ℃;
Mold temperature is: 10-20 ℃;
Injection pressure is: 50-80Mpa;
Injection cycle is: 41-52 second;
Dwell time is: 0 second;
Screw speed is: 180 rev/mins;
Through after the injection mo(u)lding, just can be made into the degradable disponsable transfusion device contact pin of various types, all size.
Table 1 has provided the used biodegradation base material prescription of part pattern disposable transfusion device contact pin.
Table 1
Beneficial effect: the base materials employed preferred polylactic acid of environmental protection and energy saving degradation type disposable transfusion device contact pin of the present invention is that material of main part is formulated with corresponding auxiliary material.Polylactic acid (PLA) is to can be used for one of degradable polymer material of human body through the only a few that FDA ratifies, has good biocompatibility, very suitablely be used for making the disposable medical instrument such as disposable transfusion device contact pin, this degradation type disposable transfusion device contact pin degradation speed is fast, safe and applicable, and need not existing disposable transfusion device contact pin mould is changed, the present invention selects take FMFORCE BIO or oyster shell powder etc. as adjuvant, be mainly used to strengthen toughening effect, and all belong to filling material utilized for environment protection, compatibility is reasonable.And when producing, its degradable material injection temperature that is used for disposable biopsy forceps is more much lower than petroleum-based plastics, and long-term production has been saved power consumption greatly, collaborative environmental protection, the energy-conservation purpose of reaching.
The specific embodiment
The prescription that following examples adopt is the prescription of above-mentioned table 1.
The injection molding forming method of embodiment 1 environmental protection and energy saving degradation type disposable transfusion device contact pin:
The first step, vacuum drying: will fill a prescription 1 or fill a prescription 2 degradable base material pellet under 52 ℃, vacuum drying 5 hours, stand-by.
Second step, injection mo(u)lding: the prescription 1 that will dry or 2 the degradable base material pellet of filling a prescription join and carry out injection mo(u)lding in the injection machine hopper.
Its barrel temperature is set as: 150 ℃ of charging apertures, 155 ℃ of compression sections, 165 ℃ of metering sections, 170 ℃ at nozzle;
Mold temperature is: 20 ℃;
Injection pressure is: first paragraph 75pa, second segment 80Mpa, the 3rd section 50Mpa;
Injection cycle is: 45 seconds;
Dwell time is: 0 second;
Screw speed is: 180 rev/mins.
Obtain adopting prescription 1 or the environmental protection and energy saving degradation type disposable transfusion device contact pin of 2 the degradable base material of filling a prescription.
Claims (3)
1. environmental protection and energy saving degradation type disposable transfusion device contact pin, it is characterized in that: described contact pin is made of the degradable base material, and its composition and weight proportion are:
100 parts of degradable macromolecule major ingredients, 18 parts of reinforcing agents;
Described macromolecule major ingredient is: polylactic acid (PLA);
Described reinforcing agent is: EMFORCE BIO, oyster shell powder or their blend;
Described oyster shell powder is 100-300 purpose oyster shell powder.
2. environmental protection and energy saving degradation type disposable transfusion device contact pin according to claim 1 is characterized in that described reinforcing agent 15-23 part;
Described reinforcing agent is: EMFORCE BIO, oyster shell powder or their blend.
3. method for preparing such as claim 1,2 described environmental protection and energy saving degradation type disposable transfusion device contact pins is characterized in that step and condition are as follows:
The first step, vacuum drying: will be for the degradable base material pellet of contact pin, under 50-60 ℃, vacuum drying 2-6 hour, stand-by;
Second step, injection mo(u)lding: the pellet that above-mentioned oven dry is used for the degradable base material of making environmental protection and energy saving degradation type disposable transfusion device contact pin, join in the injection machine hopper, carry out injection mo(u)lding by various types, the specification of environmental protection and energy saving degradation type disposable transfusion device contact pin;
Barrel temperature is set as: charging aperture 145-160 ℃, and compression section 155-165 ℃, metering section 160-175 ℃, nozzle 165-175 ℃;
Mold temperature is: 10-20 ℃;
Injection pressure is: 50-80Mpa;
Injection cycle is: 45 seconds;
Dwell time is: 0 second;
Screw speed is: 180 rev/mins;
Through after the injection mo(u)lding, just can be made into the degradable disponsable transfusion device contact pin of various types, all size.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110293589.5A CN103028166B (en) | 2011-09-29 | 2011-09-29 | Environment-friendlyand and energy-saving biodegradable type disposable infusion device thrusting needle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110293589.5A CN103028166B (en) | 2011-09-29 | 2011-09-29 | Environment-friendlyand and energy-saving biodegradable type disposable infusion device thrusting needle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103028166A true CN103028166A (en) | 2013-04-10 |
| CN103028166B CN103028166B (en) | 2016-08-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110293589.5A Expired - Fee Related CN103028166B (en) | 2011-09-29 | 2011-09-29 | Environment-friendlyand and energy-saving biodegradable type disposable infusion device thrusting needle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103028166B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152588A (en) * | 2007-10-30 | 2008-04-02 | 中国科学院长春应用化学研究所 | Degradation type disposable syringe and method of producing the same |
| CN101362853A (en) * | 2008-09-12 | 2009-02-11 | 浙江海正生物材料股份有限公司 | Low cost full-biodegradable polylactic acid sheet material and preparation method thereof |
-
2011
- 2011-09-29 CN CN201110293589.5A patent/CN103028166B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152588A (en) * | 2007-10-30 | 2008-04-02 | 中国科学院长春应用化学研究所 | Degradation type disposable syringe and method of producing the same |
| CN101362853A (en) * | 2008-09-12 | 2009-02-11 | 浙江海正生物材料股份有限公司 | Low cost full-biodegradable polylactic acid sheet material and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 周凯，顾书英，邹存洋: "《碳酸钙填充聚乳酸复合材料的制备和性能研究》", 《中国塑料》 * |
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| Publication number | Publication date |
|---|---|
| CN103028166B (en) | 2016-08-10 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Lin Jing Inventor after: Zhang Xingxing Inventor after: Wu Qianqian Inventor before: Zhang Xingxing Inventor before: Lin Jing |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20171204 Address after: 224200 Dongtai city of Jiangsu province mechanical and electronic industrial park Jinfeng Road No. 3 Patentee after: JIANGSU AOBOJIN PHARMACEUTICAL TECHNOLOGY CO.,LTD. Address before: 201600 Shanghai city Songjiang District City Private Cang Qiao Yu Jia Lu No. 37 Patentee before: SHANGHAI LINJING MEDICAL EQUIPMENT Co.,Ltd. |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160810 |