CN103007417A - Medical guide wire - Google Patents
Medical guide wire Download PDFInfo
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- CN103007417A CN103007417A CN2012104780840A CN201210478084A CN103007417A CN 103007417 A CN103007417 A CN 103007417A CN 2012104780840 A CN2012104780840 A CN 2012104780840A CN 201210478084 A CN201210478084 A CN 201210478084A CN 103007417 A CN103007417 A CN 103007417A
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- seal wire
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Abstract
The invention discloses a medical guide wire. The medical guide wire comprises an inner core made of a nickel-titanium memory alloy wire, wherein the inner core is covered with a heat-shrinkable tube sleeve made from a medical high molecular material; the outer diameter at the front end of the inner core is in continuous taper reduction; the outer diameter at the most front end of the inner core is 0.06 mm; and a medical hydrophilic coating is arranged on the surface of the medical high molecular material covering the inner core. The medical guide wire is soft, strong in flexibility and good in biocompatibility, is remarkably reduced in frictional coefficient, has the characteristic of twisting resistance, has very outstanding guide performance for guiding a vascular sheath or a catheter to move forward or enter into bending positions and for guiding the conveying process of the catheter or other interventional devices, and is favorable for guiding the catheter and the interventional devices to be quickly conveyed to in-vivo target sites in the intervention process.
Description
Technical field
The present invention relates to a kind of medical guiding wire, relate in particular to and a kind ofly be applied in the clinical blood vessel intervention and endoscopic diagnosis and treatment and use seal wire, belong to medical instruments field.
Background technology
Minimally-invasive vascular intervenien therapy technology and endoscopic technique are extensively carried out in recent years as emerging Advances in Medicine, its process is under the supervision of medical imaging device, super-selective is sent to interventional medical device a lot of vitals and the position of human body through naturally occurring blood vessel or intracoelomic cavity road, as: heart, liver, brain, kidney, digestive system and reproductive system, thereby the important technology of diagnosing and treating and method, have advantages of need not to perform the operation, wound is little, medical expense is relatively cheap.In intervention and endoscopic diagnosis and therapeutic process, seal wire arrives the important apparatus of target site as guiding all kinds of conduits and intervention apparatus, and it is essential that it is undertaking and exploring the way, leading deflection and guide to move ahead etc., and irreplaceable effect.
Seal wire in intervention and endoscopic diagnosis and the therapeutic process, should possess the following effect of following performance and performance in blood vessel.
1, front end exploration effect: the Main Function that also is seal wire.Seal wire is given prominence to the front end at conduit and intervention apparatus usually, can verify bending and narrow positions, and enters at first or by being not straight and spacious position with less and submissiveer head end.
2, whole coefficient of friction is little: be easy to send in blood vessel or in the intracoelomic cavity road, interiorly be difficult for causing the endothelium of blood vessel and body cavity walls or mucosal tissue impaired with blood vessel and body cavity walls coefficient of friction are little.
3, smooth surface: this performance can greatly reduce adhering to of material in blood and the intracoelomic cavity road, reduce thrombosis, body cavity obturation possibility.
4, bending property is good: possess the tortuous and performance by the intracoelomic cavity road of tolerance.
5, possess certain hardness: the seal wire different parts should have corresponding hardness, is beneficial to push and move ahead.
Yet because superslide seal wire inner core processing procedure is difficult to control, the surperficial superslide of seal wire is processed and is difficult to finish, on the market the compliance of seal wire and wearability poor effect.
Summary of the invention
The object of the present invention is to provide a kind of thermal contraction pipe box of medical macromolecular materials that adopts to coat the intervention guide wire for medical use that the Ultimum Ti silk is made, make seal wire have extremely outstanding guiding performance and extremely low coefficient of friction, the present invention is achieved by the following technical solutions.
A kind of medical guiding wire comprises the inner core of Ultimum Ti wire rod, and this inner core is coated with the thermal contraction pipe box of medical macromolecular materials.
Above-mentioned inner core front end external diameter becomes continuous tapering to dwindle, and external diameter is 0.06mm foremost.
There is medical hydrophilic coating on the medical macromolecular materials surface of above-mentioned coating inner core.
Described hydrophilic coating is Polyurethane.
Above-mentioned medical macromolecular materials are selected from a kind of among PE, PU, the PEBAX.
This seal wire soft flexible is strong, good biocompatibility, have kink opposing and wear-resisting characteristic, it is in the intravascular Interventional Treatment process, guiding vagina vasorum or conduit move ahead or when entering crooked position, and in gastrointestinal endoscopy and therapeutic process, guiding catheter or other intervention apparatus processes all have extremely outstanding guiding performance when carrying; Whole piece seal wire smooth surface, the water absorption rate that tool is high and lubricity can greatly lower the damage of blood vessel and reduce blood and adhere to, and are beneficial to that guiding catheter and intervention apparatus are delivered to target site in the body fast in intervention procedure.
Description of drawings
Fig. 1 is medical guiding wire core arrangement schematic diagram provided by the invention
Fig. 2 is medical guiding wire structural representation provided by the invention
Sequence number explanation among the figure: 1. NiTi wire rod front-end-cone degree is received carefully, 2. the whole section of NiTi wire rod, the 3. inner core of Ultimum Ti wire rod, 4. medical macromolecular materials thermal contraction pipe box.
Specific embodiments
In order to make technical problem to be solved by this invention, technical scheme, beneficial effect clearer, below in conjunction with drawings and Examples the present invention is further elaborated, be to be understood that, specific embodiment described herein only in order to explain the present invention, is not intended to limit the present invention.
Shown in the accompanying drawing 2, be medical guiding wire provided by the invention, the inner core 3 that comprises the Ultimum Ti wire rod, this inner core is coated with the thermal contraction pipe box 4 of medical macromolecular materials, and these medical macromolecular materials are PE, and this seal wire overall diameter is 0.8 millimeter to 1 millimeter, the external diameter of its NiTi inner core is 0.47 millimeter to 0.5 millimeter, the difference of seal wire external diameter and titanium-nickel wire external diameter is the medical high polymer clad material, and after Tu was soaked by hydrophilic Polyurethane in the seal wire surface, hot air dries formed hydrophilic coating.As shown in Figure 1, be NiTi wire rod front-end-cone degree and receive carefully by 1 in 150 millimeters scopes of this seal wire NiTi wire rod whole section 2 front ends, NiTi wire rod external diameter is from 0.47 millimeter-0.5 millimeter, and to narrow down to the external diameter of locating foremost be 0.06 millimeter to tapering continuously.The medical high polymer clad material of this seal wire can also be for PEBAX or PU etc. a kind of.
The implementation step of above-mentioned seal wire is as follows.
(1) front end of Ultimum Ti wire rod grinds to form taper.
The grinding wheel of coreless grinding machine and the guide wheel of Adjustment width precisely are adjusted into required tapering and length; Intercept the NiTi wire rod of suitable length, an end of this wire rod is sent between grinding wheel and guide wheel by locating hole, is pushed to when needing length, withdraws from fast the NiTi wire rod again, when digital display calliper confirms that tapering and length are echoed, enters next step.
(2) hot shortness's medical plastic pipe coats.
With the thermal contraction pipe box of PE, PU or PEBAX medical macromolecular materials, select suitable hot contraction ratio.As to select hot contraction ratio be that the external diameter of 2:1 is that 1.6 millimeters, internal diameter are that 1.4 millimeters PE macromolecular material heat-shrinkable tube is enclosed within on the Nitinol wire rod that forms tapering; Select again the thermal contraction operating temperature of this suitable heat-shrinkable tube, spend 120 such as the heat shrink temperature of PE material heat-shrinkable tube; The Ultimum Ti silk that packages heat-shrinkable tube fixedly is suspended on the hot-fluid change machine, finishes thermal contraction through the whole tubing of heating, whole piece Ultimum Ti silk is coated in this heat-shrinkable tube fully, and finish the terminal thermal contraction at these pipe two ends is processed.
(3) hydrophilic poly-coating.
Select the hydrophilic Polyurethane of Advansource or Hydromed by the formulated hydrophilic coating liquid, the tubing after medical macromolecular materials coat was immersed in this hydrophilic Polyurethane coating solution approximately 20 seconds at the uniform velocity fully; Propose rapidly.
(4) hot-air dry.
It is in 80 degrees centigrade the hot bellows 30 minutes that seal wire after the coating is inserted temperature, makes the body bone dry.
The water absorption rate of above-mentioned seal wire is measured relatively.
(1) seal wire of drying is positioned on the balance weighs; Again seal wire was immersed fully in 0.9% sodium chloride solution 1 minute, and be placed on the balance again after the taking-up and weigh.Seal wire weight when the seal wire weight after the water logging is deducted drying draws the water absorption rate of superslide seal wire.
(2) by above-mentioned (1) experiment, calculate the water absorption rate of not making the seal wire of coating; Compare with the water absorption rate of hydrophilic coating seal wire.
(3) seal wire water absorption rate of the present invention is 3.98%, and the water absorption rate of the best seal wire of evaluation is 3.72% in the existing market commodity.
The sliding friction experiment relatively.
5% gelatin or aqueous agar solution are heated to 60 degree dissolvings Celsius; The seal wire of not do coating processing is vertically placed glass tubing central authorities, and dissolving rear also gelatin or the aqueous agar solution of drop in temperature are poured in the glass tubing, and the seal wire upper and lower side is exposed outside the glass tubing; The seal wire of row coating is inserted equally in glass tubing central authorities, and pour into after the dissolving and gelatin or the aqueous agar solution of drop in temperature, treat gelatin or agar cooling curing.Hang respectively weights in two seal wire lower ends, observe minimum and affect weight, slip to move down weight and sliding distance.Compare difference.
Result of the test, the coefficient of friction of estimating best seal wire in the existing market commodity is 7.0, seal wire coefficient of friction of the present invention is 5.2, its minimum affect weight less, slide that it is larger to move down weight sliding distance lighter and under same tractive weight, point out seal wire sliding friction of the present invention less, sliding capability is better.
Experiment in the animal body.
Through femoral arteriography, after will puncture sheath pipe and guiding catheter are inserted, this medical guiding wire is inserted in guiding catheter, inwardly send into seal wire.The rustless steel seal wire is inserted equally, relatively frictional behaviour and the maneuvering performance of rustless steel seal wire and medical guiding wire.
The result of the test prompting, this medical guiding wire demonstrates the incomparable extremely low frictional behaviour of rustless steel seal wire and fabulous maneuvering performance.
Coating abrasion performance relatively.
Medical guiding wire coating abrasion performance of the present invention is more than at least 10 times, and the coating abrasion performance of the best seal wire of evaluation only has 10 times in the existing market commodity.
The finished product adhesiveness relatively.
Medical guiding wire finished product of the present invention is a small amount of adhesion only, and the finished product of the best seal wire of evaluation has adhesion phenomenon in the existing market commodity.
Claims (5)
1. medical guiding wire comprises the inner core of Ultimum Ti wire rod, and it is characterized in that: this inner core is coated with the thermal contraction pipe box of medical macromolecular materials.
2. medical guiding wire according to claim 1, it is characterized in that: described inner core front end external diameter becomes continuous tapering to dwindle, and external diameter is 0.06mm foremost.
3. medical guiding wire according to claim 1, it is characterized in that: there is medical hydrophilic coating on the medical macromolecular materials surface of described coating inner core.
4. medical guiding wire according to claim 3, it is characterized in that: described hydrophilic coating is Polyurethane.
5. medical guiding wire according to claim 1 is characterized in that: described medical macromolecular materials are selected from a kind of among PE, PU, the PEBAX.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104780840A CN103007417A (en) | 2012-11-22 | 2012-11-22 | Medical guide wire |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104780840A CN103007417A (en) | 2012-11-22 | 2012-11-22 | Medical guide wire |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103007417A true CN103007417A (en) | 2013-04-03 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012104780840A Pending CN103007417A (en) | 2012-11-22 | 2012-11-22 | Medical guide wire |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104548317A (en) * | 2015-01-20 | 2015-04-29 | 周玉杰 | Guiding catheter with shapeable inner core |
| JP2016150255A (en) * | 2015-02-16 | 2016-08-22 | バイオセンス・ウエブスター・(イスラエル)・リミテッドBiosense Webster (Israel), Ltd. | Angioplasty guidewire |
| CN107174722A (en) * | 2013-09-25 | 2017-09-19 | 朝日英达科株式会社 | Seal wire |
| CN107320838A (en) * | 2017-07-17 | 2017-11-07 | 佛山市迪华科技有限公司 | The forming method and equipment of a kind of PCI seal wire |
| CN108175443A (en) * | 2018-01-24 | 2018-06-19 | 深圳市凯思特医疗科技股份有限公司 | Seal wire radiography device |
| WO2018121019A1 (en) * | 2016-12-26 | 2018-07-05 | 上海英诺伟医疗器械有限公司 | Non-blood-vessel channel guidewire |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2780227Y (en) * | 2004-11-15 | 2006-05-17 | 大连健康岛科技有限公司 | Medical operation filar guide instrument |
| CN201658734U (en) * | 2010-04-02 | 2010-12-01 | 江西三鑫医疗器械集团有限公司 | Guide wire assist |
| CN202314846U (en) * | 2011-11-09 | 2012-07-11 | 张自强 | Nasal gastrointestinal tube with plastic-coated metal guide wire |
| CN202876052U (en) * | 2012-11-22 | 2013-04-17 | 湖南依微迪医疗器械有限公司 | Medical guide wire |
-
2012
- 2012-11-22 CN CN2012104780840A patent/CN103007417A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2780227Y (en) * | 2004-11-15 | 2006-05-17 | 大连健康岛科技有限公司 | Medical operation filar guide instrument |
| CN201658734U (en) * | 2010-04-02 | 2010-12-01 | 江西三鑫医疗器械集团有限公司 | Guide wire assist |
| CN202314846U (en) * | 2011-11-09 | 2012-07-11 | 张自强 | Nasal gastrointestinal tube with plastic-coated metal guide wire |
| CN202876052U (en) * | 2012-11-22 | 2013-04-17 | 湖南依微迪医疗器械有限公司 | Medical guide wire |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107174722A (en) * | 2013-09-25 | 2017-09-19 | 朝日英达科株式会社 | Seal wire |
| CN107174722B (en) * | 2013-09-25 | 2020-08-25 | 朝日英达科株式会社 | Guide wire |
| CN104548317A (en) * | 2015-01-20 | 2015-04-29 | 周玉杰 | Guiding catheter with shapeable inner core |
| CN104548317B (en) * | 2015-01-20 | 2018-06-26 | 周玉杰 | A kind of guiding catheter with shaping inner core |
| JP2016150255A (en) * | 2015-02-16 | 2016-08-22 | バイオセンス・ウエブスター・(イスラエル)・リミテッドBiosense Webster (Israel), Ltd. | Angioplasty guidewire |
| CN105879197A (en) * | 2015-02-16 | 2016-08-24 | 韦伯斯特生物官能(以色列)有限公司 | Angioplasty Guidewire |
| US11020017B2 (en) | 2015-02-16 | 2021-06-01 | Biosense Webster (Israel) Ltd. | Angioplasty guidewire |
| WO2018121019A1 (en) * | 2016-12-26 | 2018-07-05 | 上海英诺伟医疗器械有限公司 | Non-blood-vessel channel guidewire |
| CN107320838A (en) * | 2017-07-17 | 2017-11-07 | 佛山市迪华科技有限公司 | The forming method and equipment of a kind of PCI seal wire |
| CN107320838B (en) * | 2017-07-17 | 2023-10-13 | 佛山市迪华科技有限公司 | Forming method and equipment of interventional therapy guide wire |
| CN108175443A (en) * | 2018-01-24 | 2018-06-19 | 深圳市凯思特医疗科技股份有限公司 | Seal wire radiography device |
| CN108175443B (en) * | 2018-01-24 | 2022-08-23 | 深圳市凯思特医疗科技股份有限公司 | Guide wire radiography device |
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Application publication date: 20130403 |