CN102989047A - Household peritoneal dialysis liquid manufacture equipment - Google Patents
Household peritoneal dialysis liquid manufacture equipment Download PDFInfo
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- CN102989047A CN102989047A CN2012105670053A CN201210567005A CN102989047A CN 102989047 A CN102989047 A CN 102989047A CN 2012105670053 A CN2012105670053 A CN 2012105670053A CN 201210567005 A CN201210567005 A CN 201210567005A CN 102989047 A CN102989047 A CN 102989047A
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Abstract
The invention relates to medical equipment, and in particular relates to household peritoneal dialysis liquid manufacture equipment. The equipment comprises a water purifier, a medical distilled water boiler and a peritoneal dialysis liquid preparation cabinet, wherein the peritoneal dialysis liquid preparation cabinet is divided into an upper chamber and a lower chamber, the upper chamber is a preparation bin which is provided with a powdered preparation container and an ultraviolet sterilization lamp, a peritoneal dialysis liquid storage tank is arranged in the lower chamber, and the upper chamber and the lower chamber are communicated through a tubular connecting part; the water purifier is used for purifying raw water into purified water; the medical distilled water boiler is used for further producing the purified water into distilled water to prepare the peritoneal dialysis liquid; the peritoneal dialysis liquid preparation cabinet is used for mixing peritoneal dialysis liquid concentrate and the prepared injection water in the storage tank strictly in a proportion under an aseptic condition to prepare the peritoneal dialysis liquid. The peritoneal dialysis liquid manufacturing process is carried out in a closed pipeline from the beginning to the end before the peritoneal dialysis liquid which is prepared from the raw water in the water purifier enters a peritoneal dialysis machine, so that the chance of pollution can be reduced. According to the equipment, medical cost for household application can be greatly reduced, economic burden of patients can be reduced, so that the equipment is in accordance with the national condition of China with vast area and scattered patients, and is advantageous to technical popularization of APD (automatic peritoneal dialysis).
Description
Technical field
The present invention relates to armarium, particularly a kind of home-use peritoneal dialysis solution manufacturing equipment.
Background technology
Uremia is the late stage of various kidney diseases, and the replacement therapy of relying that sustains life comprises hemodialysis, peritoneal dialysis, renal transplantation.At present, particularly automatization's peritoneal dialysis of peritoneal dialysis (APD) treatment uremia has bright prospects.The full-automatic peritoneal dialysis machine of this technology utilization drives peritoneal dialysis liquid and circulates at intraperitoneal, gets rid of harmful substance, and whole process was carried out automatically at night, and effect is substantially satisfactory.This method can realize family oriented treatment, can make person between twenty and fifty the resuming work and learn in various degree that accounts for sickness rate 80%.But existing full-automatic peritoneal dialysis machine is expensive, and peritoneal dialysis liquid is in short supply and price is also too high.Therefore, the treatment of the family oriented of APD is difficult to apply under the present national conditions of China.
Applicant is high for present peritoneal dialysis machine price, prevent the problem of undue dependence on import as haemodialysis control unit, formerly obtained simple automatic peritoneal dialysis equipment (patent No. ZL201010211497.3) and two patents for invention of household automated peritoneal dialysis device (ZL201010211495.4), formerly patent has also related to the peritoneal dialysis liquid device for formulating.
Summary of the invention
The present invention is directed to the existing production of peritoneal dialysis liquid and can not solve the situation of patient's actual demand and selling at exorbitant prices, and a kind of home-use peritoneal dialysis solution manufacturing equipment is provided.
The technical solution used in the present invention is:
A kind of home-use peritoneal dialysis solution manufacturing equipment comprises water purifier, medical distilled water boiler, peritoneal dialysis liquid preparation cabinet, and described peritoneal dialysis liquid preparation cabinet divides upper and lower two Room of relative isolation, and the powder preparation container is equipped with for the storehouse of making up a prescription in upper chamber, and disposes ultraviolet disinfection lamp; Lower chamber is placed with the peritoneal dialysis liquid basin, this peritoneal dialysis liquid tank top is equipped with air filter, bottom opening is connected with the port of three-way magnetic valve A, second port of this three-way magnetic valve A is connected with the distilled water intake pipeline, and the 3rd port of this three-way magnetic valve A is connected with distilled water/peritoneal dialysis liquid export pipeline; Connected by tubular connection between described upper chamber and the lower chamber, its upper end of this tubular connection is communicated with the powder preparation container by nozzle, its lower end is communicated with the peritoneal dialysis liquid basin by electromagnetic valve, its sidepiece is connected by port of blast tube and three-way magnetic valve B, second port of this three-way magnetic valve B is connected with distilled water/peritoneal dialysis liquid export pipeline, and the 3rd port of this three-way magnetic valve B is connected with the peritoneal dialysis liquid export pipeline; On distilled water between described three-way magnetic valve A and the described three-way magnetic valve B/peritoneal dialysis liquid export pipeline force (forcing) pump is housed.
According to the technical program, water purifier is made purified water with former water (comprising tap water, direct drinking), and (microorganism and pyrogen 100% is eliminated; Electrolytical clearance rate is 95-97%); The medical distilled water boiler is further made distilled water with purified water, and its water quality meets the sterile water for injection standard, can be used for preparing peritoneal dialysis liquid; The peritoneal dialysis liquid preparation cabinet strictly mixes with the water for injection of making peritoneal dialysis liquid concentrating agents or powder under aseptic condition in proportion in basin, be mixed with peritoneal dialysis liquid.
The present invention further technical scheme is:
Its upper port of described tubular connection is placed with nozzle base, this nozzle base is the cylindrical grooves structure, inside grooves is held into the powder preparation vessel port, and nozzle is equipped with at the groove center, and described nozzle tip upwards is inserted into the powder preparation container by the bottle stopper on the powder preparation vessel port.
The air filter of described peritoneal dialysis liquid tank top is the hydrophobic air filter.
The chamber cabinet is made by stainless steel materials under the described peritoneal dialysis liquid preparation cabinet, the thermal insulation separation thermosphere of liner urethanes.
The secondary filter that is provided with the grade one filter that consisted of by the PP cotton in the described water purifier, is consisted of by activated carbon, the double-stage reverse osmosis device that is formed by force (forcing) pump and permeator.
On the distilled water intake pipeline between described medical distilled water boiler and the described peritoneal dialysis liquid basin conductivity sensor and temperature sensor are housed.
The present invention compared with prior art, its advantage and beneficial effect are:
1. equipment is taken former water (tap water or direct drinking), adopts water purifier to make purified water, and its quality has been better than state-promulgated pharmacopoeia to the requirement of purified water.
2. the purified water that adopts the medical distilled water boiler that water purifier is made is distilled, and the important indicator of institute's product distilled water is better than the sterile water for injection standard of state-promulgated pharmacopoeia regulation.
3. the peritoneal dialysis liquid preparation cabinet to sterilization, prevent that the patient infection from having strict measure: Burdick lamp is equipped with in the storehouse of making up a prescription; The time spent can not be immersed in the disinfectant solution nozzle member; The nozzle member base can be added a cover iodine furan medicated cap when dosing finishes; Dust container mouth and nozzle contact portion are convenient to the rules strict sterilization by the sterile working.
4. the manufacture process of peritoneal dialysis liquid enters water purifier from former water to enter before the peritoneal dialysis machine is to move an airtight pipeline until peritoneal dialysis liquid is made, and does not have packing, storage, transportation problem, has reduced the chance of polluting.
5. can the decrease medical treatment cost, alleviate patient's financial burden, meet the national conditions that China region is wide, the patient disperses, be conducive to the popularization of APD technology.
Description of drawings
Fig. 1 is structural representation of the present invention.
Fig. 2 is that distilled water enters peritoneal dialysis liquid basin sketch map.
Fig. 3 is that distilled water enters the dust container sketch map.
Fig. 4 is that powder solution enters peritoneal dialysis liquid basin sketch map.
Among the figure: water purifier 1, medical distilled water boiler 2, conductivity sensor 3, temperature sensor 4, distilled water intake pipeline 5, peritoneal dialysis liquid preparation cabinet 6, lower chamber 6-1, upper chamber 6-2, three-way magnetic valve A7, force (forcing) pump 8, distilled water/peritoneal dialysis liquid export pipeline 9, peritoneal dialysis liquid basin 10, three-way magnetic valve B11, electromagnetic valve 12, peritoneal dialysis liquid export pipeline 13, blast tube 14, tubular connection 15, nozzle base 16, nozzle 17, pyrogen filter 18, peritoneal dialysis device 19, ultraviolet disinfection lamp 20, powder preparation container 21, air filter 22, bottle stopper 23, thermal insulation separation thermosphere 24.
The specific embodiment
The invention will be further described below in conjunction with embodiment, and purpose only is to understand better content of the present invention.Therefore, illustrated embodiment does not limit protection scope of the present invention.
Referring to Fig. 1, this home-use peritoneal dialysis solution manufacturing equipment by for the manufacture of the water purifier 1 of purified water, with purified water through distillation make distilled water medical distilled water boiler 2, peritoneal dialysis liquid concentrating agents or powder and the water for injection made are connected to form by respective line and electromagnetic valve in peritoneal dialysis liquid preparation cabinet 6 three parts that the ratio of clinical requirement is mixed with peritoneal dialysis liquid.
The secondary filter that water purifier that present embodiment adopts 1 is provided with the grade one filter that is made of the PP cotton in it, be made of activated carbon, the double-stage reverse osmosis device that is formed by force (forcing) pump and permeator.The grade one filter filter element is that PP is cotton, and 5 microns of pore size filters can effectively filter the macromole impurity such as silt in the former water, rust, float; The secondary filter filter element is active carbon, the harmful substances such as the heterochromatic abnormal flavour of energy active adsorption, chlorine residue, part heavy metal.Former water (tap water or direct drinking) enters water purifier 1, process through the double-stage reverse osmosis device again through twice filtration, antibacterial, virus, pyrogen and Organic substance clearance rate reach 100% in the purified water that produces, and salt rejection rate is 95-97%, meets the purified water quality standard of 2010 editions state-promulgated pharmacopoeia defineds.
China pharmacopeia regulation water for injection must be through distillation, so the purified water made of water purifier 1 also must the medical distilled water boiler 2 be made distilled water with purified water.The medical distilled water boiler 2 that present embodiment adopts is the commercially available prod of 20 l/hs of aquifer yields, on the distilled water intake pipeline 5 between itself and the peritoneal dialysis liquid basin 10 conductivity sensor 3 and temperature sensor 4 is housed, with automatic control distilled water quality.The medical distilled water boiler 2 distilled water quality of producing is better than sterile water for injection standard (20 ℃ of the electrical conductivity＜1.1 us/cm of state-promulgated pharmacopoeia regulation; Bacterial endotoxin＜0.5EU/ml).
Peritoneal dialysis liquid preparation cabinet 6 shells in the present embodiment are made by stainless steel materials, the thermal insulation separation thermosphere 24 of liner urethanes.Cabinet divides up and down two Room of relative isolation, and the independent switch door is respectively arranged, and upper chamber 6-2 is the storehouse of making up a prescription, and adopts transparent doors for ease of observation, and upper chamber 6-2 is equipped with powder preparation container 21, and disposes ultraviolet disinfection lamp 20.The storehouse of making up a prescription is aseptic strict, and except establishing ultraviolet disinfection lamp 20, operator must operate by sterile working's rules.Lower chamber 6-1 is placed with peritoneal dialysis liquid basin 10, and the other air filter 22 that is equipped with of this peritoneal dialysis liquid basin 10 tank deck sides, this air filter 22 are the hydrophobic air filters of fiber of not coming off; Be equipped with three-way magnetic valve A7 and be connected with the port of three-way magnetic valve A7 at peritoneal dialysis liquid basin 10 bottom opening places, second port of this three-way magnetic valve A7 is connected with distilled water intake pipeline 5, and the 3rd port of this three-way magnetic valve A7 is connected with distilled water/peritoneal dialysis liquid export pipeline 9.Connected by tubular connection 15 between the upper chamber 6-2 of peritoneal dialysis liquid preparation cabinet 6 and the lower chamber 6-1, this tubular connection 15 adopts stainless steel pipe.Tubular connection 15 lower ends are by the upper end open welding of electromagnetic valve 12 with peritoneal dialysis liquid basin 10, and the effect of electromagnetic valve 12 is that the concentrating agents in the control powder preparation container 21 flows into tank body; Tubular connection 15 upper port are placed with nozzle base 16, this nozzle base 16 is the cylindrical grooves structure, inside grooves is held into the bottleneck of powder preparation container 21, the groove center is welded with nozzle 17, nozzle 17 point upwards are inserted into powder preparation container 21 by the bottle stopper 23 on powder preparation container 21 bottlenecks, and nozzle 17 bottoms (about 2 centimetres) pass nozzle base 16 and enter tubular connection 15 bottom tube chambers; The sidewall of tubular connection 15 and be positioned at electromagnetic valve 12 tops and have circular hole, and be connected with blast tube 14 1 ends, port of blast tube 14 other ends and three-way magnetic valve B11 is connected, second port of this three-way magnetic valve B11 is connected with distilled water/peritoneal dialysis liquid export pipeline 9, the 3rd port of this three-way magnetic valve B11 is connected with peritoneal dialysis liquid export pipeline 13, and the distilled water between three-way magnetic valve B11 and three-way magnetic valve A7/peritoneal dialysis liquid export pipeline 9 is equipped with force (forcing) pump 8.
Referring to Fig. 2, when medical distilled water boiler 2 drain valves are opened, about 95 ℃ distilled water enters peritoneal dialysis liquid basin 10 by distilled water intake pipeline 5 via the second, first port of three-way magnetic valve A7, three-way magnetic valve A7 the 3rd port and the electromagnetic valve 12 that connect distilled water/peritoneal dialysis liquid export pipeline 9 this moment are in closed condition, peritoneal dialysis liquid basin 10 interior compressed air are discharged by air filter 22, peritoneal dialysis liquid basin 10 interior distilled water reach when a certain amount of, three-way magnetic valve A7 second, the first port shutdown.30 minutes consuming time of this process, peritoneal dialysis liquid basin 10 interior temperature are 95 ℃-80 ℃, hyperthermal distilled water reached to the disinfective action of tank body and adnexa (pasteurization: 68.2 ℃ of temperature, 30 minutes, or 71.7 ℃ 15 minutes, can make bacterial population reduce 90-95%).
Referring to Fig. 3, when peritoneal dialysis liquid basin 10 interior temperature are down to 70 ℃ of left and right sides, open ultraviolet disinfection lamp 20, to upper chamber 6-2 sterilization 5 minutes; The operator that perform subsequently the sterilization preparation open the door that makes up a prescription, take off iodine furan medicated cap, from disinfectant solution, take out nozzle member (nozzle 17 and nozzle base 16 thereof) with aseptic nipper, with being placed on tubular connection 15 upper port after the Sterile Saline flushing, and the bottle stopper 23 that the tip of nozzle 17 punctures on powder preparation container 21 bottlenecks is inserted into powder preparation container 21, the chamber door is closed in the pass, uses disinfection by ultraviolet light 5 minutes again.The the 3rd and first port of three-way magnetic valve A7, the second and first port of three-way magnetic valve B11 are opened simultaneously, under the effect of force (forcing) pump 8, spray into powder preparation container 21 through distilled water/peritoneal dialysis liquid export pipeline 9, blast tube 14, tubular connection 15 bottom tube chambers 9, nozzle 17 in the peritoneal dialysis liquid basin 10, make the powder in the powder preparation container 21 dissolve (three-way magnetic valve B11 the 3rd port that be connected with peritoneal dialysis liquid export pipeline 13 1 ends this moment is in closed condition).
Referring to Fig. 4, after powder in the powder preparation container 21 dissolves, electromagnetic valve 12 is opened, concentrated solution enters peritoneal dialysis liquid basin 10 through nozzle 17 and tubular connection 15 bottom tube chambers 9, be diluted in proportion peritoneal dialysis liquid by the distilled water in the peritoneal dialysis liquid basin 10, the 3rd and first port of three-way magnetic valve A7, the second and first port of three-way magnetic valve B11 are closed simultaneously at this moment.
Still referring to Fig. 4, during begin treatment, the the 3rd and first port of three-way magnetic valve A7, the second and the 3rd port of three-way magnetic valve B11 are opened simultaneously, and peritoneal dialysis liquid enters peritoneal dialysis device 19 through distilled water/peritoneal dialysis liquid export pipeline 9, peritoneal dialysis liquid export pipeline 13, pyrogen filter 18 successively and carries out peritoneal dialysis treatment.
Peritoneal dialysis liquid preparation cabinet 6 among the present invention can consist of control system by an ARM single-chip microcomputer of the signal of collecting being put in order and programming, and its signal input comprises conductivity sensor 3 signals, temperature sensor 4 signals and gage probe signal; Its signal output comprises analog line driver (such as ultraviolet disinfection lamp 20, electromagnetic valve 12, three-way magnetic valve A7, three-way magnetic valve B11, force (forcing) pump 8) and liquid crystal display and the audible-visual annunciator of the peripheral components that is subjected to the control of ARM MCU Instruction.Water purifier 1 and medical distilled water boiler 2 have the control system of having of one's own.
Claims (6)
1. home-use peritoneal dialysis solution manufacturing equipment, comprise water purifier, medical distilled water boiler, peritoneal dialysis liquid preparation cabinet, it is characterized in that described peritoneal dialysis liquid preparation cabinet divides upper and lower two Room of relative isolation, the powder preparation container is equipped with for the storehouse of making up a prescription in upper chamber, and disposes ultraviolet disinfection lamp; Lower chamber is placed with the peritoneal dialysis liquid basin, this peritoneal dialysis liquid tank top is equipped with air filter, bottom opening is connected with the port of three-way magnetic valve A, second port of this three-way magnetic valve A is connected with the distilled water intake pipeline, and the 3rd port of this three-way magnetic valve A is connected with distilled water/peritoneal dialysis liquid export pipeline; Connected by tubular connection between described upper chamber and the lower chamber, its upper end of this tubular connection is communicated with the powder preparation container by nozzle, its lower end is communicated with the peritoneal dialysis liquid basin by electromagnetic valve, its sidepiece is connected by port of blast tube and three-way magnetic valve B, second port of this three-way magnetic valve B is connected with distilled water/peritoneal dialysis liquid export pipeline, and the 3rd port of this three-way magnetic valve B is connected with the peritoneal dialysis liquid export pipeline; On distilled water between described three-way magnetic valve A and the described three-way magnetic valve B/peritoneal dialysis liquid export pipeline force (forcing) pump is housed.
2. home-use peritoneal dialysis solution manufacturing equipment according to claim 1, it is characterized in that, its upper port of described tubular connection is placed with nozzle base, this nozzle base is the cylindrical grooves structure, inside grooves is held into the powder preparation vessel port, nozzle is equipped with at the groove center, and described nozzle tip upwards is inserted into the powder preparation container by the bottle stopper on the powder preparation vessel port.
3. home-use peritoneal dialysis solution manufacturing equipment according to claim 1 is characterized in that, the air filter of described peritoneal dialysis liquid tank top is the hydrophobic air filter.
4. home-use peritoneal dialysis solution manufacturing equipment according to claim 1 is characterized in that, the chamber cabinet is made by stainless steel materials under the described peritoneal dialysis liquid preparation cabinet, the thermal insulation separation thermosphere of liner urethanes.
5. home-use peritoneal dialysis solution manufacturing equipment according to claim 1, it is characterized in that the secondary filter that is provided with the grade one filter that consisted of by the PP cotton in the described water purifier, is consisted of by activated carbon, the double-stage reverse osmosis device that is formed by force (forcing) pump and permeator.
6. home-use peritoneal dialysis solution manufacturing equipment according to claim 1 is characterized in that, on the distilled water intake pipeline between described medical distilled water boiler and the described peritoneal dialysis liquid basin conductivity sensor and temperature sensor is housed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105670053A CN102989047A (en) | 2012-12-25 | 2012-12-25 | Household peritoneal dialysis liquid manufacture equipment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105670053A CN102989047A (en) | 2012-12-25 | 2012-12-25 | Household peritoneal dialysis liquid manufacture equipment |
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| CN102989047A true CN102989047A (en) | 2013-03-27 |
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| CN2012105670053A Pending CN102989047A (en) | 2012-12-25 | 2012-12-25 | Household peritoneal dialysis liquid manufacture equipment |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9861733B2 (en) | 2012-03-23 | 2018-01-09 | Nxstage Medical Inc. | Peritoneal dialysis systems, devices, and methods |
| US9907897B2 (en) | 2011-03-23 | 2018-03-06 | Nxstage Medical, Inc. | Peritoneal dialysis systems, devices, and methods |
| CN109432524A (en) * | 2018-11-13 | 2019-03-08 | 重庆本善医疗设备有限公司 | The system that on-line filtration prepares the ultrapure peritoneal dialysis liquid of sterile endotoxin-free |
| CN110841125A (en) * | 2019-11-05 | 2020-02-28 | 武汉市中医医院 | Peritoneal dialysis solution supply system |
| US11207454B2 (en) | 2018-02-28 | 2021-12-28 | Nxstage Medical, Inc. | Fluid preparation and treatment devices methods and systems |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US11224684B2 (en) | 2011-03-23 | 2022-01-18 | Nxstage Medical, Inc. | Peritoneal dialysis systems, devices, and methods |
| US10688234B2 (en) | 2011-03-23 | 2020-06-23 | Nxstage Medical, Inc. | Peritoneal dialysis systems, devices, and methods |
| US10688235B2 (en) | 2011-03-23 | 2020-06-23 | Nxstage Medical, Inc. | Peritoneal dialysis systems, devices, and methods |
| US10898630B2 (en) | 2011-03-23 | 2021-01-26 | Nxstage Medical, Inc. | Peritoneal dialysis systems, devices, and methods |
| US11717601B2 (en) | 2011-03-23 | 2023-08-08 | Nxstage Medical, Inc. | Dialysis systems, devices, and methods |
| US10603424B2 (en) | 2011-03-23 | 2020-03-31 | Nxstage Medical, Inc. | Peritoneal dialysis systems, devices, and methods |
| US10610630B2 (en) | 2011-03-23 | 2020-04-07 | Nxstage Medical, Inc. | Peritoneal dialysis systems, devices, and methods |
| US11433170B2 (en) | 2011-03-23 | 2022-09-06 | Nxstage Medical, Inc. | Dialysis systems, devices, and methods |
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| US9907897B2 (en) | 2011-03-23 | 2018-03-06 | Nxstage Medical, Inc. | Peritoneal dialysis systems, devices, and methods |
| US11690941B2 (en) | 2011-03-23 | 2023-07-04 | Nxstage Medical, Inc. | Peritoneal dialysis systems, devices, and methods |
| US11135348B2 (en) | 2011-03-23 | 2021-10-05 | Nxstage Medical, Inc. | Peritoneal dialysis systems, devices, and methods |
| US11433169B2 (en) | 2011-03-23 | 2022-09-06 | Nxstage Medical, Inc. | Dialysis systems, devices, and methods |
| US9861733B2 (en) | 2012-03-23 | 2018-01-09 | Nxstage Medical Inc. | Peritoneal dialysis systems, devices, and methods |
| US11872337B2 (en) | 2018-02-28 | 2024-01-16 | Nxstage Medical, Inc. | Fluid preparation and treatment devices methods and systems |
| US11364328B2 (en) | 2018-02-28 | 2022-06-21 | Nxstage Medical, Inc. | Fluid preparation and treatment devices methods and systems |
| US11207454B2 (en) | 2018-02-28 | 2021-12-28 | Nxstage Medical, Inc. | Fluid preparation and treatment devices methods and systems |
| CN109432524A (en) * | 2018-11-13 | 2019-03-08 | 重庆本善医疗设备有限公司 | The system that on-line filtration prepares the ultrapure peritoneal dialysis liquid of sterile endotoxin-free |
| CN110841125A (en) * | 2019-11-05 | 2020-02-28 | 武汉市中医医院 | Peritoneal dialysis solution supply system |
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Application publication date: 20130327 |