CN102973838B

CN102973838B - Capsule for treating chronic kidney failure syndrome

Info

Publication number: CN102973838B
Application number: CN201310001198.0A
Authority: CN
Inventors: 张冠军; 刘玉才; 刘洁
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-01-01
Filing date: 2013-01-01
Publication date: 2014-06-11
Anticipated expiration: 2033-01-01
Also published as: CN102973838A

Abstract

The invention discloses a capsule for treating a chronic kidney failure syndrome, and belongs to the field of traditional Chinese medicines. The effective constituents of the capsule comprise the following raw materials in parts by weight: 50-65 parts of white paeony root, 45-60 parts of perilla leaf, 42-58 parts of astragalus mongholicus, 38-54 parts of raw rhubarb, 34-50 parts of fructus forsythia, 30-46 parts of acorus calamus, 28-44 parts of lophatherum gracile, 25-40 parts of radix aconiti lateralis preparata, 22-26 parts of oriental wormwood, 18-22 parts of Sichuan fritillary bulb, 15-28 parts of herba leonuri, 12-25 parts of melon seed, 10-22 parts of blackberry lily, 8-18 parts of akebiaquinata, 5-15 parts of radix cyathulae and 3-12 parts of mirabilite powder. According to the invention, the raw materials complement each other, and the capsule is prepared by scientifically mixing the Chinese herbal medicines with the effects of warming the kidney, benefiting the spleen, descending the turbid, regulating the middle warmer, dredging water passage, tonifying the spleen and kidney, dredging the organs, descending the turbid, and promoting diuresis to remove toxic materials, is specially used for treating kidney and spleen-yang deficiency, turbid accumulation, spleen and kidney-yang deficiency, and water retention and toxin predominance, has a very good treatment effect for various complications of the chronic kidney failure syndrome, and can effectively prolong the survival time of a uremia patient and improve the life quality of the patient.

Description

A kind of capsule that is used for the treatment of chronic kidney exhaustion syndrome

Affiliated technical field

The present invention relates to the field of Chinese medicines, relate in particular to a kind of capsule that is used for the treatment of chronic kidney exhaustion syndrome.

Background technology

Chronic renal failure, refers to that various nephropathys cause renal function irreversibility to go down, until the clinical syndrome that the series of symptoms that afunction occurs and metabolism disorder form is called for short chronic kidney hypofunction, develops into whole latter stage, is the uremia it has often been said.Uremia is not an independently disease, but the total clinical syndrome of various nephropathy in late period, is the syndrome that series of clinical manifestations that chronic renal failure occurs while entering end stage eventually forms.

Uremic morbidity base reason, the most common with metabolic acidosis and water, electrolyte balance disorder.If the material such as phosphoric acid, sulphuric acid is because of the acatharsia retention of kidney, can there is " uremic acidosis " in the acid product of body metabolism.When renal insufficiency, the adaptive capacity that kidney overloads to sodium or capacity is too much declines gradually, can cause volume load excessive, common subcutaneous dropsy and Celom liquid loading in various degree.Kidney row potassium capability declines gradually, easily occurs hyperpotassemia.In calcium phosphorus generation, is penetrated disorder, main manifestations be phosphorus too much and calcium deficiency, even can cause secondary hyperparathyroidism.In addition, chronic kidney hypofunction also shows the pathological changes of cardiovascular system, respiratory system, gastrointestinal system, blood system, neuromuscular system and skeleton aspect.

To uremic Therapeutic Method, can only be undertaken by the mode of artificial replacement kidney work, i.e. general said dialysis at present.Dialysis is exactly to replace kidney work, in the time that patient enters Uremic, kidneys of patients should damage and exceed more than 90%, do not take replacement therapy if at this moment delayed always, toxin retains in body so, also can bring irreversible infringement, as heart, digestive system, skeleton, blood system etc. to other internal organs of health, and uremia be Drug therapy can not curable disease, do not exist and so-calledly can cure uremic " miraculous cure ".

Existing Drug therapy, just alleviates uremia's symptom to a certain extent, as utilizes calcium preparation to resist high potassium to myocardium toxicity; Utilize sodium lactate or sodium bicarbonate to promote that potassium ion enters in cell, the inhibition of antagonism potassium to heart; Utilize glucose and insulin combination application, promote that potassium shifts in cell; Potassium diuretic is arranged in oral or injection, promotes kidney row potassium; Oral cation exchange power fat, promotes potassium to drain from intestinal; The treatment such as heart tonifying, expander.Hormones, antagonism class medicine that these aspects adopt, have certain side effect conventionally, in alleviating uremia's symptom, also can bring extra burden to health.

Traditional Chinese medical theory is thought, kidney disease is to contain because kidney deficiency of spleen-YANG, aqueous vapor are spread unchecked, in turbid pathogen that superinverse, spleen kidney yang decline, water retention poison is contained institute and caused, can only be by regulating body function, activating immune system is alleviated or is recovered, treat to the ill, should with warming the kidney and strengthening the spleen, the turbid descending and in, promoting diuresis by dispersing lung-QI, warming and recuperating the spleen and kidney, logical dirty the turbid descending, diuresis rush down malicious Chinese crude drug and carry out prescription.

Summary of the invention

The invention provides a kind of capsule that is used for the treatment of chronic kidney exhaustion syndrome, have warming the kidney and strengthening the spleen, the turbid descending and in, promoting diuresis by dispersing lung-QI, diuresis rush down effect of poison, cures the disease and ask source treating both the principal and secondary aspects of a disease, and the various complication of uremia are all had to fabulous therapeutic effect.

For achieving the above object, technical scheme of the present invention is implemented as follows:

Be used for the treatment of a capsule for chronic kidney exhaustion syndrome, raw material composition and the parts by weight of making described capsule effective ingredient are:

38～54 parts of 42～58 parts of Radix Et Rhizoma Rhei of 45～60 parts of Radix Astragali Preparatas of 50～65 parts of Folium Perillae of the Radix Paeoniae Alba

25～40 parts of 28～44 parts of Radix Aconiti Lateralis Preparata of 30～46 portions of Herba Lophatheris of 34～50 portions of Rhizoma Acori Gramineis of Fructus Forsythiae

12～25 parts of 15～28 parts of Semen Momordicae Charantiaes of 18～32 parts of Herba Leonuris of 22～36 parts of Bulbus Fritillariae Cirrhosae of Herba Artemisiae Scopariae

3～12 parts of 5～15 parts of mirabilite powders of 8～18 portions of Radix Cyathulaes of 10～22 portions of Caulis Akebiaes of Rhizoma Belamcandae.

Raw material composition and the parts by weight of making described capsule effective ingredient are:

42～50 parts of 45～55 parts of Radix Et Rhizoma Rhei of 48～58 parts of Radix Astragali Preparatas of 52～62 parts of Folium Perillae of the Radix Paeoniae Alba

28～36 parts of 30～40 parts of Radix Aconiti Lateralis Preparata of 33～43 portions of Herba Lophatheris of 36～46 portions of Rhizoma Acori Gramineis of Fructus Forsythiae

15～23 parts of 18～26 parts of Semen Momordicae Charantiaes of 21～29 parts of Herba Leonuris of 25～33 parts of Bulbus Fritillariae Cirrhosae of Herba Artemisiae Scopariae

5～9 parts of 8～12 parts of mirabilite powders of 10～16 portions of Radix Cyathulaes of 12～18 portions of Caulis Akebiaes of Rhizoma Belamcandae.

46 parts of 50 parts of Radix Et Rhizoma Rhei of 53 parts of Radix Astragali Preparatas of 57 parts of Folium Perillae of the Radix Paeoniae Alba

32 parts of 35 parts of Radix Aconiti Lateralis Preparata of 38 portions of Herba Lophatheris of 41 portions of Rhizoma Acori Gramineis of Fructus Forsythiae

19 parts of 22 parts of Semen Momordicae Charantiaes of 25 parts of Herba Leonuris of 29 parts of Bulbus Fritillariae Cirrhosae of Herba Artemisiae Scopariae

7 parts of 10 parts of mirabilite powders of 13 portions of Radix Cyathulaes of 15 portions of Caulis Akebiaes of Rhizoma Belamcandae.

A preparation method that is used for the treatment of the capsule of chronic kidney exhaustion syndrome, comprises following processing step:

(1) Radix Astragali Preparata, Radix Et Rhizoma Rhei, Radix Aconiti Lateralis Preparata, Radix Cyathulae are pulverized and ground into powder, cross 160 order fine powders, for subsequent use.

(2) mirabilite powder is immersed in the water of aliquot, dissolve, medicinal liquid is for subsequent use.

(3) Folium Perillae, Fructus Forsythiae, Rhizoma Acori Graminei, Herba Lophatheri, Herba Artemisiae Scopariae, Herba Leonuri, Caulis Akebiae are put into container, add the water of six times of amounts, soak after 8～10 hours, get immersion; In remaining medicinal residues, add again the water of four times of amounts, soak after 5～7 hours, get immersion; Merge twice gained immersion, heating evaporation, under 60 DEG C of environment of simmer down to, the thick paste of relative density 1.10～1.15, for subsequent use.

(4) Radix Paeoniae Alba, Rhizoma Belamcandae, Bulbus Fritillariae Cirrhosae, Semen Momordicae Charantiae are put into container, add the shao-hsing rice wine of four times of amounts, after heated and boiled, continue to soak 4～6 hours, get immersion; In remaining medicinal residues, add again the shao-hsing rice wine of triplication, after heated and boiled, continue to soak 2～3 hours, get immersion; Merge twice gained immersion, heating evaporation, under simmer down to room temperature environment, the thick paste of relative density 1.15～1.20, for subsequent use.

(5) by the medicinal liquid of the fine powder of step (1) gained, step (2) gained, the thick paste making with step (3), step (4) mixes, and after stirring, quick-freezing becomes powder, is prepared as capsule product with modern crafts.

The property of medicine of the present invention's Chinese medicine used is as follows:

The Radix Paeoniae Alba: bitter in the mouth; Property is put down.Enter liver; Spleen channel.Nourishing blood to suppress the hyperactive liver, slow middle pain relieving; Yin fluid astringing is received antiperspirant.Cure mainly the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency." not Lu " carries: " clear and coherent blood vessels, slow in, dispelling malignant blood, expelling extravasated blood, the gas that anhydrates, sharp bladder, intestine and small intestine, subduing inflammation, row cold and heat while controlling, attacked by pestiferous factors stomachache, lumbago." modern medicine study confirms; the Radix Paeoniae Alba can regulate immunity; strengthen macrophage and leukocytic phagocytic function; regulate the immunologic function of T lymphocyte and body fluid; protect the liver, spasmolytic, analgesia, calmness, resist cool, cooling effect; in addition smooth muscle is had to inhibitory action, the effect of enhancing anoxia enduring, antioxidation and resisting fatigue.

Folium Perillae: acrid in the mouth; Warm in nature.Return lung; Spleen; Stomach warp.Expelling cold and relieving exterior syndrome; Dispersing lung-QI and dissipating phlegm; Circulation of qi promoting and in; Antiabortive; Cowfish Eriocheir sinensis poison.Cure mainly exterior syndrome due to wind-cold; Cough with copious phlegm; Gastral cavity distension; Nausea and vomiting; Stomachache is vomited and diarrhoea; Nausea discord; Gestation is disliked cloudy; Ichthyophagy Eriocheir sinensis is poisoning." book on Chinese herbal medicine converge with speech " carries: " cold expelling gas, lung heat clearing gas, alleviating distention in middle-JIAO gas, antiabortive gas, lower stagnation of QI, the gas that reduces phlegm, be control gas refreshing medicine also." modern medicine study shows, Folium Perillae water extraction liquid can shorten blood clotting time, blood plasma recalcification time and activated partial thromboplastin time, promotes enterokinesia, in addition antipyretic, antibacterial, blood glucose increasing and sedation in addition.

Radix Astragali Preparata: sweet in the mouth; Warm in nature.Enter the heart; Lung; Spleen; Kidney channel.Invigorating QI to consolidate the body surface resistance; Diuresis; Expelling pus and toxin by strengthening QI; Promoting tissue regeneration and ulcer healing.Cure mainly the cardiopalmus of breathing hard; Asthenia; Weak; Spontaneous perspiration; Night sweat; Chronic diarrhea; Proctoptosis; Body is impractical swollen; Uterine prolapse; Chronic nephritis; Carbuncle is difficult bursts; Or burst and do not hold back for a long time." Xinhua's book on Chinese herbal medicine outline " carries: " have the function of invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, granulation promoting." modern medicine study confirmation; Radix Astragali main component is Radix Astragali total flavones, Radix Astragali Mongolici total polysaccharide, Radix Astragali total saponins and aminoacid etc.; have diuretic antihypertensive, anti-inflammatory analgesic, heart tonifying, antioxidant radical generation and improve the multiple pharmacological effect such as body's immunity; can act on from many aspects body, improve the relevant blood vessel sexually transmitted disease (STD) change patients' such as cardiovascular, cerebrovascular, diabetes, nephropathy the function such as hemodynamics and vascular endothelial cell.

Radix Et Rhizoma Rhei: bitter in the mouth; Cold in nature.Enter stomach; Large intestine; Liver; Spleen channel.Attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.Cure mainly excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; Edema abdominal distention; Dysuria; Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; WEIJIA is gathered; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald." Japan hanako materia medica " carries: " sharp joint, rushes down and stops up stagnant, aqueous vapor for logical all gas of a surname, blood circulation regulating, extremity unbalanced cold and heat, and warm miasma heat-phlegm, sharp defecation, and apply all furuncle carbuncle poison." modern medicine study confirmation; Radix Et Rhizoma Rhei has broad-spectrum antiviral, antibacterial and antimycotic effect; can be used for the control of various inflammation; the effective ingredient of Radix Et Rhizoma Rhei can be eliminated oxygen-derived free radicals; suppress lipid peroxidation; have anti-aging effects, have in addition outstanding adjusting immunologic function, diseases of urinary system is had to prevention and therapeutical effect clearly.

Fructus Forsythiae: bitter in the mouth; Cold nature.Enter lung; The heart; Gallbladder meridian.Heat-clearing and toxic substances removing; Dispersing swelling and dissipating binds.Cure mainly anemopyretic cold; Epidemic febrile disease; Pyretic stranguria urine retention; Carbuncle; Toxic swelling; Scrofula; Goiter; Sore throat.Shennong's Herbal carries: " main cold and heat, scrofula, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat." clinic study shows; Fructus Forsythiae has broad-spectrum antibacterial action; staphylococcus aureus, Hayes dysentery bacterium are had to very strong inhibitory action; other pathogenic bacterium, influenza virus, fungus are had to certain inhibitory action; contained oleanolic acid has heart tonifying, diuresis and hypotensive activity; Citrin can reduce vascular permeability and fragility, prevents haemolysis, also has in addition that tell in antiinflammatory, town, anti-liver injury effect.

Rhizoma Acori Graminei: acrid in the mouth; Bitter; Slightly warm in nature.Enter the heart; Liver; Spleen channel.Waking up the patient from unconsciousness by dissipating phlegm; Removing dampness circulation of qi promoting; The sharp numbness of dispeling the wind; Reducing swelling and alleviating pain.Cure mainly calentura coma; Syncope due to accumulation of phlegm; Forgetful; Tinnitus; Deaf; Abdominal distention; Fasting dysentery; Rheumatic arthralgia; Traumatic injury; Carbuncle scabies." book on Chinese herbal medicine meets former " carries: " deficiency of heart-QI person should it, tonifying five ZANG-organs, happy hole, logical nine orifices, improve visual and auditory acuity." modern medicine study confirms, Rhizoma Acori Graminei has the unify effect of digestive system of central nervous system, autonomic nervous system, hormonal system, cardiovascular system that regulates.

Herba Lophatheri: sweet in the mouth; Light; Cold in nature.GUIXIN; Small intestinal; Lung; Stomach warp.Heat clearing away; Relieving restlessness; Diuresis.Cure mainly dysphoria with smothery sensation thirsty; Aphtha of the mouth and tongue; Gingival swelling and pain; Children's's night crying due to fright in infant; Hot urination; Stranguria with turbid discharge." the SHENGCAO property of medicine standby will " carries: " expectorant is quenched the thirst, and except part of the body cavity above the diaphragm housing the heart and lungs fire, bright eyes, diuresis, controls nebulousurine, brings down a fever, loose hemorrhoid poison." modern medicine study shows, Herba Lophatheri has significant refrigeration function, can increase the excretion of urine chloride, and staphylococcus aureus, Hemolytic streptococcus are had to inhibitory action, the effect of the blood glucose that raises in addition in addition.

Radix Aconiti Lateralis Preparata: acrid in the mouth; Bitter; Warm in nature; Poisonous.Enter stomach; Liver Channel.Expectorant dispels the wind; The meridian dredging; Removing toxic substances analgesia.Curing mainly middle wind-phlegm stops up; Facial hemiparalysis; Migraine; Tetanus; Venom; Scrofula tuberculosis; Carbuncle." book on Chinese herbal medicine converges and says " carries: ", by cold phlegm, the violent medicine of getting round by bribery also for recuperating depleted YANG gas, loose YIN-cold." modern medicine study shows; Radix Aconiti Lateralis Preparata can strengthen myocardial contraction; accelerate heart rate, and blood vessel dilating increases blood flow; improve blood circulation; antibody gram, arrhythmia, cardiac muscle is had to protective effect, cold resistance; improve hypoxia-bearing capability, also has in addition antiinflammatory, analgesia, enhancing immunity, antithrombotic to form, suppress the effects such as lipid peroxidation, slow down aging.

Herba Artemisiae Scopariae: mildly bitter flavor; Micro-pungent; Cold nature.Enter spleen; Stomach; Urinary bladder channel.Clearing away heat-damp and promoting diuresis; Jaundice eliminating.Cure mainly jaundice; Dysuria; Eczema pruritus." Japan hanako materia medica " carries: " disease while controlling day row, fanatical, headache head revolves, wind-eye pain, subtertian malaria, woman's lump in the abdomen, and interior damage is weary absolutely." modern medicine study shows; Herba Artemisiae Scopariae can promote gallbladder hidropoiesis and excretion; participate in the metabolism of bile acid, bilirubin, class ester and some poisonous substance; reduce blood fat, coronary artery dilating, promotion fibrinolytic, and the effect such as antipyretic, blood pressure lowering, antibacterial, antiinflammatory in addition has remarkable inhibition to the mutagenic action of AFB1; can promote leukocyte division; increase leukocyte number simultaneously in addition, improves the immunocompetence of T cell, participates in the effect such as immunomodulating and inducement interferon of body.

Bulbus Fritillariae Cirrhosae: sweet in the mouth; Bitter; Cold nature.Return lung; Heart channel.Clearing heat and moistening lung; Preventing phlegm from forming and stopping coughing; Mass dissipating and swelling eliminating.Cure mainly the deficiency of the lung; Chronic cough; Cough due to consumptive disease; Cough caused by dryness-heat; Lung abscess; Scrofula; Carbuncle; Acute mastitis." Changsha medicine solution " carries: " property of Bulbus Fritillariae Uninbracteatae bitter cold, the cool gold that expels the heat-evil, the turbid descending expectorant, its power is non-little, so clearing heat in the lung and here praiseworthy unbeaten gastric qi is very." modern medicine study confirmation, Bulbus Fritillariae Cirrhosae has significant antitussive and phlegm-dispelling functions, significantly suppresses pepsin and stress ulcer, suppresses central nervous system.

Herba Leonuri: acrid in the mouth; Bitter; Property micro-enter.Return liver; Kidney; Pericardium channel.Promoting blood flow to regulate menstruation; Inducing diuresis to remove edema; Heat-clearing and toxic substances removing.Cure mainly menoxenia; Amenorrhea; Vaginal bleeding during pregnancy difficult labour; Retention of placenta; Puerperal blood faints; Abdominal pain due to blood stasis; Traumatic injury; Dysuria; Edema; Carbuncle skin infection." book on Chinese herbal medicine is looked for the truth " carries: " the water promoting the circulation of blood that disappears, removes crazy tissue regeneration promoting, and regulating menstruation removing toxic substances, for wanting agent after tire front tyre." modern medicine study shows; the leonurine that Herba Leonuri is contained etc. has excitation to uterus; antiplatelet aggregation, coagulation; improve coronary circulation, cardioprotection; strengthen cardiac contractile force; direct excited respiratory center, and the slow intestinal tube tonicity of speeding, also has the effects such as maincenter inhibition, bacteriostatic in addition.

Semen Momordicae Charantiae: bitter in the mouth; Sweet; Warm in nature.Enter kidney; Spleen channel.Warming and recuperating the kidney-YANG.Cure mainly insufficiency of kidney-YANG; Frequent micturition; The enuresis; Seminal emission; Sexual impotence.Compendium of Material Medica is carried: " QI invigorating tonifying YANG." modern medicine study shows; Semen Momordicae Charantiae fibre rich, carbohydrate, fatty oil, Fructus Momordicae charantiae glucoside and grip altogether linoleic acid, can improve gastrointestinal function, reduce gastrointestinal disease or cancer chance occur; QI invigorating tonifying YANG, also has good curative effect to male spermatorrhea and infertility.

Rhizoma Belamcandae: bitter in the mouth; Cold in nature; Poisonous.Enter lung; Liver Channel.Pathogenic fire reducing; Removing toxic substances; Loose blood; Expectorant.Cure mainly sore throat pharyngalgia; Cough with dyspnea; Accumulation and obstruction of sputum; Scrofula tuberculosis; Malaria with splenomegaly; Women's amenorrhea; Carbuncle sore tumefacting virus." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control laryngopharynx swelling and pain, acute throat trouble is closed in pharynx, tonsillitis, and Zha rib redness, root of the tooth is swollen rotten, attacks the diseases such as loose all pyretic toxicity of carbuncle sore." modern medicine study confirmation, Rhizoma Belamcandae has and suppresses and retarding action some virus in diseases caused by exogenous pathogenic factor and throat illness.

Caulis Akebiae: bitter in the mouth; Cold in nature; Poisonous.Enter the heart; Small intestinal; Urinary bladder channel.Clearing heart fire; Treating stranguria; Stimulating milk secretion is stimulated the menstrual flow.Cure mainly hot urination; Pouring brimful of tears; Edema; Dysphoria with smothery sensation in the heart; Aphtha of the mouth and tongue; Leucorrhea; Amenorrhea; Puerperal galactostasis; Damp and hot arthralgia pain." Chinese Pharmacopoeia " carries: " purge heat, pathogenic fire reducing.Control aphtha of the mouth and tongue, hot urination." modern medicine study confirmation, the contained aristolochic acid A of Caulis Akebiae has the cytophagous phagocytic function of enhancing, can improve cellular immune function, has significant diuresis.

Radix Cyathulae: sweet in the mouth; Micro-hardship, property is flat.Return liver, kidney channel.Eliminating blood stasis and inducing menstruation; Easing joint movement; Inducing diuresis for treating stranguria syndrome.For amenorrhea lump in the abdomen; Retention of placenta; Arthralgia; Flaccidity of the lower limbs clonic spasm of the muscle; Injury from falling down." Chinese medicinal herbal " carries: " removing blood stasis declines, and controls to beat and flutters knife injury, has the effect that relaxes pain." modern medicine study confirmation, Radix Cyathulae has obvious analgesic activity, and contained insectean metamorphosis steroid hormone and Herba Cyathulae Prostratae steroid paulownia have protein assimilation.

Mirabilite powder: salty in the mouth; Bitter; Cold in nature.Return stomach; Lung; Spleen; Kidney; Small intestinal; Three warmers; Large intestine channel.

Purging heat to relax the bowels; Moistening for dryness and softening hard mass; The detumescence of relieving inflammation or internal heat.Cure mainly excess-heat constipation; Constipation due to dry stool; Stagnant stomachache; Acute appendicitis swells and ache; Acute mastitis; Swelling and pain of hemorrhoid.Modern medicine study shows, Natrii Sulfas can increase enteral moisture, cause mechanical stimulus, promote enterokinesia, the reticuloendothelial system of vermiform appendix and spleen is had to obvious stimulation, strengthen hypertrophy and phagocytic activity, transfer in addition in addition the inherent resistance against diseases of body, accelerate the effects such as lymph generation, detumescence, pain relieving, diuresis.

The present invention compared with prior art, has following beneficial effect:

Prescription polarization of the present invention is leaned on mutually, select possess warming the kidney and strengthening the spleen, the turbid descending and in, promoting diuresis by dispersing lung-QI, warming and recuperating the spleen and kidney, logical dirty the turbid descending, diuresis rush down the Chinese crude drug of malicious effect, be carefully dished up and form through science compatibility, specialize in kidney deficiency of spleen-YANG, turbid pathogen contain, spleen kidney yang declines, water retention poison is contained, various complication to chronic kidney exhaustion all have fabulous therapeutic effect, can effectively extend the time-to-live of uremic patient, improve Quality of Life of Patients.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further elaborated.

Embodiment 1

Raw material composition and the weight of capsule effective ingredient of the present invention are:

Radix Paeoniae Alba 62g Folium Perillae 56g Radix Astragali Preparata 53g Radix Et Rhizoma Rhei 50g

Fructus Forsythiae 46g Rhizoma Acori Graminei 42g Herba Lophatheri 39g Radix Aconiti Lateralis Preparata 36g

Herba Artemisiae Scopariae 32g Bulbus Fritillariae Cirrhosae 29g Herba Leonuri 25g Semen Momordicae Charantiae 22g

Rhizoma Belamcandae 19g Caulis Akebiae 16g Radix Cyathulae 12g mirabilite powder 10g.

The processing step of capsule preparation method thereof of the present invention is:

Usage and dosage: adult every day 3 times, each 0.5～0.75g, two hours after meal with warm water delivery service; Patient with severe symptoms every day 4 times, each 0.5～1.0g, takes with warm yellow wine for two hours after meal.Within 7 days, be a course for the treatment of, common 3～5 onsets course for the treatment of, 5～7 onsets course for the treatment of of patient with severe symptoms.

Embodiment 2

Radix Paeoniae Alba 57g Folium Perillae 53g Radix Astragali Preparata 50g Radix Et Rhizoma Rhei 46g

Fructus Forsythiae 41g Rhizoma Acori Graminei 38g Herba Lophatheri 35g Radix Aconiti Lateralis Preparata 32g

Herba Artemisiae Scopariae 29g Bulbus Fritillariae Cirrhosae 25g Herba Leonuri 22g Semen Momordicae Charantiae 19g

Rhizoma Belamcandae 15g Caulis Akebiae 13g Radix Cyathulae 10g mirabilite powder 7g.

Capsule preparation method thereof processing step and the usage and dosage of the present embodiment are identical with embodiment 1.

Embodiment 3

Radix Paeoniae Alba 54g Folium Perillae 48g Radix Astragali Preparata 45g Radix Et Rhizoma Rhei 42g

Fructus Forsythiae 38g Rhizoma Acori Graminei 35g Herba Lophatheri 32g Radix Aconiti Lateralis Preparata 28g

Herba Artemisiae Scopariae 25g Bulbus Fritillariae Cirrhosae 22g Herba Leonuri 19g Semen Momordicae Charantiae 15g

Rhizoma Belamcandae 13g Caulis Akebiae 10g Radix Cyathulae 8g mirabilite powder 5g.

Clinical data:

Show through clinical verification data tracing, capsule of the present invention is the symptom of the various complication of relieve chronic kidney exhaustion effectively, especially high to the effective percentage of cardiovascular system, blood system and neuromuscular system, be applicable to the treatment of uremic patient, be suitable for clinical application.

Claims

1. a capsule that is used for the treatment of chronic kidney exhaustion syndrome, is characterized in that: raw material composition and the parts by weight of making described capsule effective ingredient are:

2. a kind of capsule that is used for the treatment of chronic kidney exhaustion syndrome according to claim 1, is characterized in that: raw material composition and the parts by weight of making described capsule effective ingredient are:

3. a kind of capsule that is used for the treatment of chronic kidney exhaustion syndrome according to claim 1, is characterized in that: raw material composition and the parts by weight of making described capsule effective ingredient are:

4. a preparation method that is used for the treatment of the capsule of chronic kidney exhaustion syndrome as described in claim 1-3 any one, is characterized in that: comprise following processing step:

(1) Radix Astragali Preparata, Radix Et Rhizoma Rhei, Radix Aconiti Lateralis Preparata, Radix Cyathulae are pulverized and ground into powder, cross 160 order fine powders, for subsequent use;

(2) mirabilite powder is immersed in the water of aliquot, dissolve, medicinal liquid is for subsequent use;

(3) Folium Perillae, Fructus Forsythiae, Rhizoma Acori Graminei, Herba Lophatheri, Herba Artemisiae Scopariae, Herba Leonuri, Caulis Akebiae are put into container, add the water of six times of amounts, soak after 8～10 hours, get immersion; In remaining medicinal residues, add again the water of four times of amounts, soak after 5～7 hours, get immersion; Merge twice gained immersion, heating evaporation, under 60 DEG C of environment of simmer down to, the thick paste of relative density 1.10～1.15, for subsequent use;

(4) Radix Paeoniae Alba, Rhizoma Belamcandae, Bulbus Fritillariae Cirrhosae, Semen Momordicae Charantiae are put into container, add the shao-hsing rice wine of four times of amounts, after heated and boiled, continue to soak 4～6 hours, get immersion; In remaining medicinal residues, add again the shao-hsing rice wine of triplication, after heated and boiled, continue to soak 2～3 hours, get immersion; Merge twice gained immersion, heating evaporation, under simmer down to room temperature environment, the thick paste of relative density 1.15～1.20, for subsequent use;