CN102972401A - 2, 5-diphenylthiophene nano microcapsule preparation for preventing lygocoris lucorum and method for preparing 2, 5-diphenylthiophene nano microcapsule preparation for preventing lygocoris lucorum - Google Patents
2, 5-diphenylthiophene nano microcapsule preparation for preventing lygocoris lucorum and method for preparing 2, 5-diphenylthiophene nano microcapsule preparation for preventing lygocoris lucorum Download PDFInfo
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Abstract
The invention discloses a 2, 5-diphenylthiophene nano microcapsule preparation for preventing lygocoris lucorum and a method for preparing the 2, 5-diphenylthiophene nano microcapsule preparation for preventing lygocoris lucorum, which belong to the technical field of pesticides. A complex coacervation method is adopted to prepare the 2, 5-diphenylthiophene nano microcapsule preparation, capsule-core ingredients mainly contain an active ingredient, namely 0.1-40wt% of 2, 5-diphenylthiophene, and the capsule-core ingredient and a capsule wall material are used to prepare the 2, 5-diphenylthiophene nano microcapsule preparation. The prepared nano microcapsule has high effect on the lygocoris lucorum and thoroughly kills pests, and the preparation has less pollution to environments, has good sustained-release and controlled-release functions, is low in production cost and is suitable for preventing the lygocoris lucorum.
Description
Technical field
The present invention relates to technical field of pesticide, particularly is the preparing technical field of the capsule of nano preparation of capsule-core active ingredient with 2,5-diphenyl thiophene.
Background technology
Photo-activation pesticide is the Recent study focus, enter the nineties in 20th century after, China has also begun the research to the insect killing via photoactivation agent.1993, the reported first such as Xu Hanhong Artemisia scoparia (
Artemisia scoparia) in the essential oil Capillene to prodenia litura (
Spodoptera litura) the photoactivation cytotoxicity, represent beginning of domestic research insect killing via photoactivation agent.After this domestic each research unit begins the system research to the insect killing via photoactivation agent.Though α-terthienyl has good photoactivation cytotoxicity to various insects, but since α-terthienyl photoactivation activity is found there be more than 30 year, use in always fail extensive field, main cause is that its half life period in environment is too short, synthetic difficulty is larger, and cost is high, suitability for industrialized production faces a lot of problems.Be applied to the deficiencies such as field in order to overcome the photo-activation pesticides such as α-terthienyl, to have excellent photo-activation pesticide α-terthienyl as template, utilize biological principle such as the row of grade, replace thiphene ring with phenyl ring, synthetic 2,5-diphenyl thiophene, thus improve the photostability of insect killing via photoactivation agent and reduced production cost, prolong the lasting period, thereby improve its field using value.Studies show that as having early stage 2,5-diphenyl thiophene shows excellent photoactivation toxic action, LC to diamond-back moth 3 instar larvaes
50Value is respectively 267.87 μ g/mL, and α-terthienyl to diamond-back moth 3 instar larvae LC
50Value is 222.22 μ g/mL, and both activities is suitable.Mainly concentrate at present insecticidal activity and the analysis and detection technology of 2,5-diphenyl thiophene about the research of 2,5-diphenyl thiophene.But 2,5-diphenyl thiophene preparation has run into series of problems in the actual use in field, such as 2, the 5-diphenyl thiophene is in natural environment or photodissociation, hydrolysis etc. easily occur, make drug effect, the lasting effect of 2,5-diphenyl thiophene be subject to impact, the control efficiency of insect has been subject to certain impact.
Gelatin and gum Arabic are as the cyst material of microcapsules, have good biocompatibility, biological degradability, bioadhesive and avirulence, can wrap up agricultural chemicals by modes of action such as chemical crosslinking, Electrostatic Absorption, form one deck semipermeable membrane on the agricultural chemicals surface.Owing to will overcome the obstruction of macromolecular skeleton during the release of agricultural chemicals, thereby make the farm chemical release time lengthening, reach the purpose of sustained-release and controlled release.
Summary of the invention
The object of the present invention is to provide a kind of insecticide efficiency high, have good slow-release function green plant bug had 2 of excellent preventive and therapeutic effect, 5-diphenyl thiophene capsule of nano preparation and preparation method, adopt the spherical looks of microcapsules of complex coacervation preparation good, good dispersion, particle diameter is evenly distributed, controlled-release effect is remarkable, can effectively control the harm of green plant bug.
Technical scheme of the present invention is: 2 of control green plant bug, the capsule of nano preparation of 5-diphenyl thiophene, it is characterized in that, by capsule-core active ingredient 2,5-diphenyl thiophene and cyst wall assistant agent material are made, described capsule-core active ingredient 2, the 5-diphenyl thiophene accounts for total formulation weight amount 0.1～40%, and all the other are cyst wall assistant agent material.
Preferred version is: described capsule-core active ingredient 2, the 5-diphenyl thiophene accounts for 0.1～10% of total formulation weight amount.
Described cyst wall assistant agent material comprises acetone, 3% gumwater, 3% aqueous gelatin solution, distilled water, glutaraldehyde; Acetone, 3% gumwater, 3% aqueous gelatin solution, distilled water, glutaraldehyde are respectively cyst wall assistant agent material volume percentage: acetone 8.5～9.5%, 3% gumwater 21～24%, 3% aqueous gelatin solution 21～24%, distilled water 43～47%, glutaraldehyde 0.8～1.5%.
2 of above-mentioned control green plant bug, the preparation method of the capsule of nano preparation of 5-diphenyl thiophene is characterized in that, may further comprise the steps:
1) will account for 2 of total formulation weight amount 0.1～40%, the 5-diphenyl thiophene acetone ultrasonic dissolution that accounts for cyst wall assistant agent material volume 8.5～9.5%;
2) lysate that step 1) is obtained adds 3% gumwater that accounts for cyst wall assistant agent material volume 21～24%, heat to 45 ℃ of stirrings, add again 3% aqueous gelatin solution 21～24% that accounts for cyst wall assistant agent material volume 21～24%, mixing speed is 500 rev/mins, and the glacial acetic acid of slow dropping 10% transfers to 4.2 with its pH value in the whipping process;
3) to step 2) final stirring liquid in add 34 ℃～35 ℃ distilled water accounting for cyst wall assistant agent material volume 43～47% and continue to stir, mixing speed is 1000 rev/mins, treat that solution is cooled to below 30 ℃ naturally, putting ice bath plunges after 10 ℃, add 37% glutaraldehyde that accounts for cyst wall assistant agent material volume 0.8～1.5%, solidify 0.5 h;
4) consolidation liquid with step 3) transfers to pH to 8～9 with 20% NaOH, in ice bath, continue to stir, after solidifying 3 h, by the centrifugal capsule of nano that wets that obtains, wash again to without behind the glutaraldehyde, carry out freezing drying under reduced pressure, make 2 of control green plant bug, the capsule of nano preparation of 5-diphenyl thiophene, microcapsules are spherical.
Capsule-core active ingredient of the present invention selected 2,5-diphenyl thiophene in time large tracts of land is controlled diffusion and the propagation of green plant bug effectively, because the action site of insect killing via photoactivation agent variation, green plant bug is difficult for developing immunity to drugs to it, and selected 2,5-diphenyl thiophene low toxicity, low to environmental selection pressure, the capsule of nano preparation has been avoided not enough, the relatively not high drawback of control efficiency of the lasting effect of medicament.Adopt complex coacervation of the present invention preparation the control green plant bug 2, the spherical looks of the capsule of nano preparation of 5-diphenyl thiophene are good, good dispersion, particle diameter is evenly distributed, controlled-release effect is remarkable, can effectively control the harm of green plant bug.
Description of drawings
Fig. 1 be the embodiment of the invention 3 make 2,5-diphenyl thiophene capsule of nano Electronic Speculum picture.
Fig. 2 be the embodiment of the invention 4 make 2,5-diphenyl thiophene capsule of nano Electronic Speculum picture.
Embodiment
The following embodiment that passes through further specifies technical solution of the present invention, but content of the present invention is not limited to this.
Specific embodiment 1:
Take by weighing 2,5-diphenyl thiophene, 0.0010 g, with 20 mL acetone ultrasonic dissolutions, add 3% gumwater, 50 mL, 45 ℃ of stirrings, mixing speed is 500 rev/mins, adds the aqueous gelatin solution of 50 mL 3% again.The glacial acetic acid of slow dropping 10% transfers to 4.2 with its pH value in the whipping process, adds distilled water 100 mL about 35 ℃ again, and mixing speed is 1000 rev/mins, treat that solution is cooled to below 30 ℃ naturally, put ice bath and plunge after 10 ℃, add 37% glutaraldehyde, 2 mL, solidify 0.5 h, transfer to pH to 8～9 with 20% NaOH, in ice bath, continue to stir, solidify 3 h, centrifugal, wash to without glutaraldehyde, freezing drying under reduced pressure obtains the finished product microcapsules.Take the capsule of nano photo by environmental scanning electronic microscope, can see prepared microcapsules for spherical, the average diameter of prepared capsule of nano is 228 nm; The medicament envelop rate is 81.17%, preparation be 0.027% 2,5-diphenyl thiophene capsule of nano.
Specific embodiment 2:
Take by weighing 2,5-diphenyl thiophene, 2.5000 g, with 20 mL acetone ultrasonic dissolutions, add 3% gumwater, 50 mL, 45 ℃ of stirrings, mixing speed is 800 rev/mins, adds the aqueous gelatin solution of 50 mL 3% again.The glacial acetic acid of slow dropping 10% transfers to 4.2 with its pH value in the whipping process, adds distilled water 100 mL about 35 ℃ again, and mixing speed is 1000 rev/mins, treat that solution is cooled to below 30 ℃ naturally, put ice bath and plunge after 10 ℃, add 37% glutaraldehyde, 2 mL, solidify 0.5 h, transfer to pH to 8～9 with 20% NaOH, in ice bath, continue to stir, solidify 3 h, centrifugal, wash to without glutaraldehyde, freezing drying under reduced pressure obtains the finished product capsule of nano.Take the capsule of nano photo by environmental scanning electronic microscope, can see, prepared microcapsules are spherical, and the average diameter of capsule of nano is 199 nm; The medicament envelop rate is 80.05%, preparation be 40% 2,5-diphenyl thiophene capsule of nano.
Specific embodiment 3:
Take by weighing 2,5-diphenyl thiophene, 0.4200 g, with 20 mL acetone ultrasonic dissolutions, add 3% gumwater, 50 mL, 45 ℃ of stirrings, mixing speed is 1100 rev/mins, adds the aqueous gelatin solution of 50 mL 3% again.The glacial acetic acid of slow dropping 10% transfers to 4.2 with its pH value in the whipping process, adds distilled water 100 mL about 35 ℃ again, and mixing speed is 1000 rev/mins, treat that solution is cooled to below 30 ℃ naturally, put ice bath and plunge after 10 ℃, add 37% glutaraldehyde, 2 mL, solidify 0.5 h, transfer to pH to 8～9 with 20% NaOH, in ice bath, continue to stir, solidify 3 h, centrifugal, wash to without glutaraldehyde, freezing drying under reduced pressure obtains the finished product capsule of nano.Take the capsule of nano photo by environmental scanning electronic microscope, can see prepared capsule of nano for spherical, the average diameter of microcapsules is 125 nm; The medicament envelop rate is 81.02%, preparation be 10% 2,5-diphenyl thiophene capsule of nano.
Specific embodiment 4:
Take by weighing 2,5-diphenyl thiophene, 0.2500 g, with 20 mL acetone ultrasonic dissolutions, add 3% gumwater, 50 mL, temperature control is 45 ℃ of stirrings, and mixing speed is 1400 rev/mins, adds the aqueous gelatin solution of 50 mL 3% again.The glacial acetic acid of slow dropping 10% transfers to 4.2 with its pH value in the whipping process, adds distilled water 100 mL about 35 ℃ again, and mixing speed is 1000 rev/mins, treat that solution is cooled to below 30 ℃ naturally, put ice bath and plunge after 10 ℃, add 37% glutaraldehyde, 3 mL, solidify 0.5 h, transfer to pH to 8～9 with 20% NaOH, in ice bath, continue to stir, solidify 3 h, centrifugal, wash to without glutaraldehyde, freezing drying under reduced pressure obtains the finished product capsule of nano.Take the capsule of nano photo by environmental scanning electronic microscope, can see prepared microcapsules for spherical, the average diameter of capsule of nano is 231nm; The medicament envelop rate is 80.99%, preparation be 6.25% 2,5-diphenyl thiophene capsule of nano.
Specific embodiment 5:
Take by weighing 2,5-diphenyl thiophene 0.5000g, with 20 mL acetone ultrasonic dissolutions, add 3% gumwater, 50 mL, temperature control is 45 ℃ of stirrings, and mixing speed is 1100 rev/mins, adds the aqueous gelatin solution of 50 mL 3% again.The glacial acetic acid of slow dropping 10% transfers to 4.2 with its pH value in the whipping process, adds distilled water 100 mL about 35 ℃ again, and mixing speed is 1000 rev/mins, treat that solution is cooled to below 30 ℃ naturally, put ice bath and plunge after 10 ℃, add 37% glutaraldehyde, 2 mL, solidify 0.5 h, transfer to pH to 8～9 with 20% NaOH, in ice bath, continue to stir, solidify 3 h, centrifugal, wash to without glutaraldehyde, freezing drying under reduced pressure obtains the finished product capsule of nano.Take the capsule of nano photo by environmental scanning electronic microscope, can see prepared microcapsules for spherical, the average diameter of capsule of nano is 203 nm; The medicament envelop rate is 80.01%, preparation be 11.76% 2,5-diphenyl thiophene capsule of nano.
Specific embodiment 6:
Take by weighing 2,5-diphenyl thiophene, 0.1250 g, with 20 mL acetone ultrasonic dissolutions, add 3% gumwater, 50 mL, temperature control is 45 ℃ of stirrings, and mixing speed is 1700 rev/mins, adds the aqueous gelatin solution of 50 mL 3% again.The glacial acetic acid of slow dropping 10% transfers to 4.2 with its pH value in the whipping process, adds distilled water 100 mL about 35 ℃ again, and mixing speed is 1000 rev/mins, treat that solution is cooled to below 30 ℃ naturally, put ice bath and plunge after 10 ℃, add 37% glutaraldehyde, 2 mL, solidify 0.5 h, transfer to pH to 8～9 with 20% NaOH, in ice bath, continue to stir, solidify 3 h, centrifugal, wash to without glutaraldehyde, freezing drying under reduced pressure obtains the finished product capsule of nano.Take the capsule of nano photo by environmental scanning electronic microscope, can see the standby microcapsules of institute system for spherical, the average diameter of capsule of nano is 237 nm; The medicament envelop rate is 80.58%, preparation be 0.33% 2,5-diphenyl thiophene capsule of nano.
Specific embodiment 7:
Take by weighing 2,5-diphenyl thiophene, 2.000 g, with 20 mL acetone ultrasonic dissolutions, add 3% gumwater, 50 mL, temperature control is 45 ℃ of stirrings, and mixing speed is 1800 rev/mins, adds the aqueous gelatin solution of 50 mL 3% again.The glacial acetic acid of slow dropping 10% transfers to 4.2 with its pH value in the whipping process, adds distilled water 100 mL about 35 ℃ again, and mixing speed is 1100 rev/mins, treat that solution is cooled to below 30 ℃ naturally, put ice bath and plunge after 10 ℃, add 37% glutaraldehyde, 2 mL, solidify 0.5 h, transfer to pH to 8～9 with 20% NaOH, in ice bath, continue to stir, solidify 3 h, centrifugal, wash to without glutaraldehyde, freezing drying under reduced pressure obtains the finished product capsule of nano.Take the capsule of nano photo by environmental scanning electronic microscope, can see prepared capsule of nano for spherical, the average diameter of microcapsules is 219 nm; The medicament envelop rate is 79.94%, preparation be 34.78% 2,5-diphenyl thiophene capsule of nano.
Specific embodiment 8:
2,5-diphenyl thiophene capsule of nano preparation field control green plant bug (
Apolygus lucorum) test effect.With 0.027% 2,5-diphenyl thiophene capsule of nano (embodiment 1), 40.0% 2,5-diphenyl thiophene capsule of nano (embodiment 2), 10.0% 2,5-diphenyl thiophene capsule of nano (embodiment 3), 6.25% 2,5-diphenyl thiophene capsule of nano (embodiment 4) and 11.76% 2,5-diphenyl thiophene capsule of nano (embodiment 5), 0.33% 2,5-diphenyl thiophene capsule of nano (embodiment 6) and 34.78% 2,5-diphenyl thiophene capsule of nano (embodiment 7), diluting respectively 2000 times of sprayings processes on the serious cotton plants of hazards of lygus lucorum, 2 of blank and corresponding concentration is set simultaneously, the contrast of 5-diphenyl thiophene cream preparation, every processing repeats 3 times.Test the quantity of investigating respectively green plant bug after 7 days, 14 days, calculate the insect population decline rate.Test data statistics SAS software analysis.Result of the test sees Table 1:
Each preparation spray-on process control green plant bug field control effectiveness test of table 1
| Process | 7 days insect population decline rates (%) | 14 days insect population decline rates (%) |
| CK | 0 | 0 |
| 0.027% 2,5-diphenyl thiophene capsule of nano agent | 50.17j | 37.28m |
| 40.0% 2,5-diphenyl thiophene capsule of nano agent | 100.0a | 95.86a |
| 10% 2,5-diphenyl thiophene capsule of nano agent | 90.74c | 86.16e |
| 6.25% 2,5-diphenyl thiophene capsule of nano agent | 83.53f | 62.13i |
| 11.76% 2,5-diphenyl thiophene capsule of nano agent | 92.56b | 88.29d |
| 0.33% 2,5-diphenyl thiophene capsule of nano agent | 75.41h | 52.56j |
| 34.78% 2,5-diphenyl thiophene capsule of nano agent | 100.0a | 92.21b |
| 0.027% 2,5-diphenyl thiophene missible oil | 45.18k | 28.44n |
| 40.0% 2,5-diphenyl thiophene missible oil | 100.0a | 90.17c |
| 10% 2,5-diphenyl thiophene missible oil | 88.75d | 73.67h |
| 6.25% 2,5-diphenyl thiophene missible oil | 80.99g | 42.87l |
| 11.76% 2,5-diphenyl thiophene missible oil | 85.47e | 75.41g |
| 0.33% 2,5-diphenyl thiophene missible oil | 68.24i | 44.71k |
| 34.78% 2,5-diphenyl thiophene missible oil | 100.0a | 81.13f |
As can be seen from Table 1, process after 7 days, 14 days 2, the agent of 5-diphenyl thiophene capsule of nano all is better than 2 of respective concentration to the control efficiency of green plant bug, 5-diphenyl thiophene cream preparation, illustrate that the capsule of nano agent of 2,5-diphenyl thiophene more can satisfy the demand of preventing and treating of green plant bug.
Claims (4)
1. prevent and treat 2 of green plant bug, the capsule of nano preparation of 5-diphenyl thiophene is characterized in that, by capsule-core active ingredient 2,5-diphenyl thiophene and cyst wall assistant agent material are made, described capsule-core active ingredient 2, the 5-diphenyl thiophene accounts for total formulation weight amount 0.1～40%, and all the other are cyst wall assistant agent material.
2. 2 of control as claimed in claim 1 green plant bug, the capsule of nano preparation of 5-diphenyl thiophene is characterized in that, described capsule-core active ingredient 2, and the 5-diphenyl thiophene accounts for 0.1～10% of total formulation weight amount.
3. 2 of control as claimed in claim 1 green plant bug, the capsule of nano preparation of 5-diphenyl thiophene is characterized in that, described cyst wall assistant agent material comprises acetone, 3% gumwater, 3% aqueous gelatin solution, distilled water, glutaraldehyde; It is acetone 8.5～9.5%, 3% gumwater 21～24%, 3% aqueous gelatin solution 21～24%, distilled water 43～47%, glutaraldehyde 0.8～1.5% that acetone, 3% gumwater, 3% aqueous gelatin solution, distilled water, glutaraldehyde are respectively cyst wall assistant agent material volume percentage.
4. such as 2 of the described control of claims 1 to 3 green plant bug, the preparation method of the capsule of nano preparation of 5-diphenyl thiophene is characterized in that, may further comprise the steps:
1) will account for 2 of total formulation weight amount 0.1～40%, the 5-diphenyl thiophene acetone ultrasonic dissolution that accounts for cyst wall assistant agent material volume 8.5～9.5%;
2) lysate that step 1) is obtained adds 3% gumwater that accounts for cyst wall assistant agent material volume 21～24%, heat to 45 ℃ of stirrings, add again 3% aqueous gelatin solution 21～24% that accounts for cyst wall assistant agent material volume 21～24%, mixing speed is 500 rev/mins, and the glacial acetic acid of slow dropping 10% transfers to 4.2 with its pH value in the whipping process;
3) to step 2) final stirring liquid in add 34 ℃～35 ℃ distilled water accounting for cyst wall assistant agent material volume 43～47% and continue to stir, mixing speed is 1000 rev/mins, treat that solution is cooled to below 30 ℃ naturally, putting ice bath plunges after 10 ℃, add 37% glutaraldehyde that accounts for cyst wall assistant agent material volume 0.8～1.5%, solidify 0.5 h;
4) consolidation liquid with step 3) transfers to pH to 8～9 with 20% NaOH, in ice bath, continue to stir, after solidifying 3 h, by the centrifugal capsule of nano that wets that obtains, wash again to without behind the glutaraldehyde, carry out freezing drying under reduced pressure, make 2 of control green plant bug, the capsule of nano preparation of 5-diphenyl thiophene.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104607119A (en) * | 2015-01-23 | 2015-05-13 | 上海应用技术学院 | Acetic acid styracin nanometer capsule and preparation method thereof |
| CN109938047A (en) * | 2019-03-14 | 2019-06-28 | 同济大学 | Gelatin-gum arabic microcapsules of natural pyrethrin and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL47687A (en) * | 1975-07-10 | 1979-01-31 | Uniroyal Inc | Acaricidal or insecticidal compositions containing substituted thiophenes, methods of controlling acarid or insect pests therewith and certain new substituted thiophenes |
| CN1304786A (en) * | 2000-11-17 | 2001-07-25 | 华南理工大学 | Oil-contained high-granularity high-strength microcapsule and its preparing process |
| CN101209248A (en) * | 2007-12-21 | 2008-07-02 | 东华大学 | Preparation of tamoxifen citrate microcapsule prepared by complex coacervation method |
-
2012
- 2012-12-06 CN CN201210517783.1A patent/CN102972401B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL47687A (en) * | 1975-07-10 | 1979-01-31 | Uniroyal Inc | Acaricidal or insecticidal compositions containing substituted thiophenes, methods of controlling acarid or insect pests therewith and certain new substituted thiophenes |
| CN1304786A (en) * | 2000-11-17 | 2001-07-25 | 华南理工大学 | Oil-contained high-granularity high-strength microcapsule and its preparing process |
| CN101209248A (en) * | 2007-12-21 | 2008-07-02 | 东华大学 | Preparation of tamoxifen citrate microcapsule prepared by complex coacervation method |
Non-Patent Citations (8)
| Title |
|---|
| 《Journal of Molecular Structure (Theochem)》 19951231 Dawn C.S. Friedmana et al A theoretical study of 2,2';5',2"-terthiophene (alpha-T) and its analogs. Part 1. Correlation of electronic structure and energies with herbicidal phototoxicity 71-78 1-4 , 第333期 * |
| 《农药》 20090630 何冠茹等 alpha-三联噻吩微胶囊的制备及其光活化性能 414-416,428 1-4 第48卷, 第06期 * |
| DAWN C.S. FRIEDMANA ET AL: "A theoretical study of 2,2’;5’,2"-terthiophene (α-T) and its analogs. Part 1. Correlation of electronic structure and energies with herbicidal phototoxicity", 《JOURNAL OF MOLECULAR STRUCTURE (THEOCHEM)》, no. 333, 31 December 1995 (1995-12-31), pages 71 - 78 * |
| 何冠茹等: "α-三联噻吩微胶囊的制备及其光活化性能", 《农药》, vol. 48, no. 06, 30 June 2009 (2009-06-30) * |
| 刑福保: "辣素/明胶-阿拉伯胶-单宁微囊和纳囊的研究", 《中国优秀硕博学位论文全文数据库（博士）工程科技I辑》, no. 4, 31 December 2004 (2004-12-31), pages 020 - 7 * |
| 易金娥等: "阿维菌素微囊的制备及其体外释药的研究", 《湖南农业大学学报(自然科学版)》, vol. 32, no. 01, 28 February 2006 (2006-02-28), pages 67 - 69 * |
| 蒋志胜等: "光活化农药的研究与应用", 《农药学学报》, vol. 3, no. 01, 31 March 2001 (2001-03-31), pages 1 - 5 * |
| 陈小军等: "二苯基噻吩活性氧量子产率、杀虫活性及稳定性研究", 《中国农业科学》, vol. 39, no. 01, 31 December 2006 (2006-12-31), pages 81 - 87 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104607119A (en) * | 2015-01-23 | 2015-05-13 | 上海应用技术学院 | Acetic acid styracin nanometer capsule and preparation method thereof |
| CN109938047A (en) * | 2019-03-14 | 2019-06-28 | 同济大学 | Gelatin-gum arabic microcapsules of natural pyrethrin and preparation method thereof |
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