CN102954995A - Non-uniform electric field based ion mobility spectrometer - Google Patents
Non-uniform electric field based ion mobility spectrometer Download PDFInfo
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- CN102954995A CN102954995A CN2011102403465A CN201110240346A CN102954995A CN 102954995 A CN102954995 A CN 102954995A CN 2011102403465 A CN2011102403465 A CN 2011102403465A CN 201110240346 A CN201110240346 A CN 201110240346A CN 102954995 A CN102954995 A CN 102954995A
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Abstract
The invention discloses a non-uniform electric field based ion mobility spectrometer. The ion mobility spectrometer comprises an ionization source, an ion gate, electrode rings, potentiometers, resistors, a detection electrode and an amplifier. A sample is carried to an ionization region by a carrying gas, and is ionized by the ionization source to form sample ions; pulses control the ion gate to open, and the sample ions enter a drift region; the sample ions form a non-uniform electric field in a mobility tube through adjusting the potentiometers and the resistors; the sample ions are separated under the common action of the non-uniform electric field and a drift gas flow, and successively arrive the detection electrode; and the sample ions are amplified by the amplifier and are detected by a signal output device. The non-uniform electric field based ion mobility spectrometer can effectively improve the ion transmission efficiency and the detection sensitivity.
Description
Technical field
The present invention relates to a kind of analyzing device, specifically a kind of based on the inhomogeneous field ion mobility spectrometry.This device can improve the sensitivity of ion transmission efficiency and detection greatly.
Background technology
The Atmospheric Chemistry analytical approach is always by the research topic of human institute extensive concern.In recent years terrorist activity is constantly upgraded, environmental pollution aggravates, some areas drug trade is spread unchecked day by day, and the mankind put into research with a large amount of manpower and materials and have highly sensitive, the simple analytical instrument of equipment, detect drugs, excitant, anesthetic and explosive.In military affairs, the every field such as public safety have a large amount of demands for good detecting instrument at present.The present invention proposes at this Demand Base.
IMS is a new detection technique that grows up from late 1960s, and it is under atmospheric pressure or nearly atmospheric pressure, and molion is in the signature analysis time of drift tube per sample, a kind of instrument that minimum gas is detected.Its principle of work is: sample is entered by the carrier gas carrier band, and the sample ions that then is ionized enters reaction zone.The sample ions that reaction zone forms is under the control of ion gate by pulse, and the release reaction ion enters the drift region.Under the acting in conjunction of electric field and carrier gas, the ion isolation of different quality number and impact radius successively arrives and detects the utmost point, amplifies signal output through amplifier, reaches testing goal.
Insufficient sensitivity, signal to noise ratio (S/N ratio) is low to be the problem that present ion mobility spectrometry faces.The present invention is intended to heighten ion transmission efficiency by the current field condition that changes ion mobility spectrometry, thereby improves widely its sensitivity.
Summary of the invention
The purpose of this invention is to provide a kind of based on the inhomogeneous field ion mobility spectrometry; It can improve ion transmission efficiency and detection sensitivity greatly, can efficiently carry out fast the Site Detection analysis;
For achieving the above object, the technical solution used in the present invention is:
A kind ofly comprise divider resistance based on the inhomogeneous field ion mobility spectrometry, described divider resistance is in series by resistance and adjustable potentiometer.
Described divider resistance is more than 2 or 2, and the resistance of adjacent divider resistance is different.
Electrode retaining collar links to each other with the high-pressure side of power supply with the adjustable potentiometer dividing potential drop by resistance, can change the voltage that is carried on the electrode retaining collar by regulator potentiometer, the resistance of adjacent divider resistance of being connected with adjustable potentiometer by resistance is different, thereby forms the electric field of non-uniform Distribution in ion mobility spectrometry.
When detection of positive ions, this inhomogeneous field distributes along the trend that the carrier gas direction is exponential taper; When detecting negative ion, the trend that then is exponential increasing distributes; The electric field of non-uniform Distribution has better focusing and laser propagation effect to ion.
Be specially: a kind ofly comprise ionization source based on the inhomogeneous field ion mobility spectrometry, ion gate, electrode retaining collar, potentiometer and resistance, and amplifier and signal output apparatus.Electrode retaining collar is parallel distribution, mutually insulated between them.
It is three parts that whole migration spectrum is divided into, and the flow direction along sample gas is followed successively by ionized region, reaction zone and migration area.
Ionization source places the carrier gas inlet position.The electrode retaining collar of varying number becomes parallel distribution, consists of reaction zone and migration area.Electrode retaining collar links to each other with high-pressure side with the adjustable potentiometer dividing potential drop by resistance.Establish the detection utmost point and signal output apparatus at the rear portion of minute uniform field.
Can change the voltage that is carried on the electrode retaining collar by regulator potentiometer, thereby in ion mobility spectrometry, form the electric field of non-uniform Distribution.The electric field of non-uniform Distribution has better focusing and laser propagation effect to ion.
When carrying out sample analysis, sample enters ionized region through the carrier gas carrier band, is ionized to ion, enters reaction zone.Ion gate is by the pulse gauge tap, and the release reaction ion enters the drift region.Ion drifts about in the ion mobility spectrometry that inhomogeneous field distributes, and the ion isolation of different quality number and impact radius successively arrives and detects the utmost point, amplifies signal output through amplifier, reaches testing goal.
Of the present invention simple in structure, under the condition of same structure parameter, ion and band point particulate are had focusing effect (shown in the accompanying drawing 2), therefore have very high sensitivity.Can efficiently carry out fast the Site Detection analysis.Can provide a kind of efficiently detection method fast for multiple gases sample and charged Nanometer Aerosol Particles.
Description of drawings
Fig. 1 is structural representation of the present invention; 1 is ionization source among the figure, and 2 is ion gate, and 3 is electrode retaining collar, and 4 for detecting the utmost point, and 5 is amplifier, and 6 is adjustable potentiometer, and 7 is resistance, and 8 is earth terminal, and 9 is the high-pressure side of power supply, and 10 are carrier gas, and 11 for floating gas, and 12 is ion.
Fig. 2 is the ion trajectory figure that inhomogeneous field and uniform electric field are assembled ion: (a) be the focusing effect of inhomogeneous field; (b) be the focusing effect of uniform electric field.
Embodiment
See also shown in Figure 1.A kind of based on the inhomogeneous field ion mobility spectrometry, comprise ionization source 1, ion gate 2, electrode retaining collar 3, amplifier 4, signal output apparatus 5 and divider resistance, divider resistance is made of resistance 7 and adjustable potentiometer 6 series connection;
It is three parts that whole migration spectrum is divided into, and the flow direction along sample gas is followed successively by ionized region, reaction zone and migration area, and ionization source 1 places the carrier gas inlet position; 3 one-tenth parallel distributions of electrode retaining collar of a plurality of (this example is 12) quantity consist of reaction zone and migration area;
Electrode retaining collar 3 links to each other with high-pressure side with adjustable potentiometer 6 dividing potential drops by resistance 7.Can change the voltage that is carried on the electrode retaining collar 3 by regulator potentiometer 6, apply different voltage at electrode retaining collar 3, thereby in ion mobility spectrometry, form the electric field of non-uniform Distribution.Establish the detection utmost point 4 and amplifier 5 at the rear portion of non homogen field.
When detection of positive ions, this inhomogeneous field distributes along the trend that the carrier gas direction is exponential taper; When detecting negative ion, the trend that then is exponential increasing distributes.The electric field of non-uniform Distribution has better focusing and laser propagation effect to ion.Electrode retaining collar 3 is parallel distribution, mutually insulated between them.
When carrying out sample analysis, sample enters ionized region through carrier gas 10 carrier bands, is ionized source 1 and is ionized into ion 12, enters reaction zone.Ion gate 2 is by the pulse gauge tap, and the release reaction ion enters the drift region.Ion 12 drifts about in the ion mobility spectrometry that inhomogeneous field distributes, and the particle beams is focused under the effect of inhomogeneous field.Because different quality number and the impact radius of ion, they successively arrive detects the utmost point 4, amplifies through amplifier 5 signal is exported by signal output system, reaches testing goal.
Fig. 2 is the ion trajectory figure that inhomogeneous field and uniform electric field are assembled ion: (a) be the focusing effect of inhomogeneous field; Carrier gas and float gas gas and be air in this case, the actual conditions of magnitude of voltage and resistance value is followed successively by on the electrode retaining collar:
(b) be the focusing effect of uniform electric field.Carrier gas and float gas gas and be air in this case, the actual conditions of magnitude of voltage and resistance value is on the electrode retaining collar:
Claims (4)
1. one kind based on the inhomogeneous field ion mobility spectrometry, comprises divider resistance, it is characterized in that:
Described divider resistance is in series by resistance (7) and adjustable potentiometer (6).
2. ion mobility spectrometry as claimed in claim 1 is characterized in that:
Described divider resistance is more than 2 or 2, and the resistance of adjacent divider resistance is different.
3. ion mobility spectrometry as claimed in claim 1 is characterized in that:
Electrode retaining collar links to each other with the high-pressure side of power supply with the adjustable potentiometer dividing potential drop by resistance, can change the voltage that is carried on the electrode retaining collar by regulator potentiometer, the resistance of adjacent divider resistance of being connected with adjustable potentiometer (6) by resistance (7) is different, thereby forms the electric field of non-uniform Distribution in ion mobility spectrometry.
4. ion mobility spectrometry as claimed in claim 3 is characterized in that:
When detection of positive ions, this inhomogeneous field distributes along the trend that the carrier gas direction is exponential taper; When detecting negative ion, the trend that then is exponential increasing distributes; The electric field of non-uniform Distribution has better focusing and laser propagation effect to ion.
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103887141A (en) * | 2014-03-25 | 2014-06-25 | 清华大学深圳研究生院 | Ionic migration spectrometer |
| CN104392889A (en) * | 2014-12-14 | 2015-03-04 | 中国科学院合肥物质科学研究院 | Ion mobility spectrometer and method for controlling ion gate by using alternating current superposition method |
| CN104713940A (en) * | 2013-12-13 | 2015-06-17 | 中国科学院大连化学物理研究所 | Novel on-fingerprint prohibited good spectrum detection device and method and application thereof |
| CN105319284A (en) * | 2014-07-18 | 2016-02-10 | 中国科学院大连化学物理研究所 | Gas-chromatography ion-mobility-spectrometry combined use method |
| CN105632874A (en) * | 2014-11-07 | 2016-06-01 | 中国科学院大连化学物理研究所 | DC non-uniform electric field ion migration tube |
| CN107407658A (en) * | 2015-03-09 | 2017-11-28 | 株式会社岛津制作所 | Parallel plate-type non-uniform electric field ionic mobility light-dividing device |
| US9874543B2 (en) | 2014-01-14 | 2018-01-23 | Shimadzu Corporation | Ion mobility analyzer and mass spectrometer |
| CN108091537A (en) * | 2016-11-21 | 2018-05-29 | 中国科学院大连化学物理研究所 | A kind of ladder Field ion mobility pipe |
| CN108878252A (en) * | 2018-07-02 | 2018-11-23 | 中国科学院电子学研究所 | Ion mobility spectrometry drift region multiplexer and method |
| CN110491766A (en) * | 2018-11-25 | 2019-11-22 | 中国科学院大连化学物理研究所 | A kind of direct current inhomogeneous field transference tube |
| CN110828281A (en) * | 2019-11-15 | 2020-02-21 | 中国科学院大连化学物理研究所 | Ion enrichment ion migration tube |
| CN111029241A (en) * | 2019-12-19 | 2020-04-17 | 中国科学院合肥物质科学研究院 | Ion mobility spectrometer and method for compensating ion mobility speed |
| CN111739784A (en) * | 2019-03-25 | 2020-10-02 | 哈米尔顿森德斯特兰德公司 | Ion source of ion mobility spectrometer |
| CN112490108A (en) * | 2020-11-24 | 2021-03-12 | 中国科学院大连化学物理研究所 | Ion gate control method for automatically enriching ions |
| CN114047245A (en) * | 2021-11-24 | 2022-02-15 | 中国科学院大连化学物理研究所 | Ion-molecule reaction selection control measuring device based on ion mobility spectrometry |
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Cited By (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104713940A (en) * | 2013-12-13 | 2015-06-17 | 中国科学院大连化学物理研究所 | Novel on-fingerprint prohibited good spectrum detection device and method and application thereof |
| US9874543B2 (en) | 2014-01-14 | 2018-01-23 | Shimadzu Corporation | Ion mobility analyzer and mass spectrometer |
| CN103887141B (en) * | 2014-03-25 | 2016-05-04 | 清华大学深圳研究生院 | A kind of ionic migration spectrometer |
| CN103887141A (en) * | 2014-03-25 | 2014-06-25 | 清华大学深圳研究生院 | Ionic migration spectrometer |
| CN105319284B (en) * | 2014-07-18 | 2017-07-21 | 中国科学院大连化学物理研究所 | A kind of method for combined use of gas-chromatography and ion mobility spectrometry |
| CN105319284A (en) * | 2014-07-18 | 2016-02-10 | 中国科学院大连化学物理研究所 | Gas-chromatography ion-mobility-spectrometry combined use method |
| CN105632874A (en) * | 2014-11-07 | 2016-06-01 | 中国科学院大连化学物理研究所 | DC non-uniform electric field ion migration tube |
| CN105632874B (en) * | 2014-11-07 | 2017-09-26 | 中国科学院大连化学物理研究所 | A kind of direct current inhomogeneous field transference tube |
| CN104392889B (en) * | 2014-12-14 | 2017-04-26 | 中国科学院合肥物质科学研究院 | Ion mobility spectrometer and method for controlling ion gate by using alternating current superposition method |
| CN104392889A (en) * | 2014-12-14 | 2015-03-04 | 中国科学院合肥物质科学研究院 | Ion mobility spectrometer and method for controlling ion gate by using alternating current superposition method |
| CN107407658A (en) * | 2015-03-09 | 2017-11-28 | 株式会社岛津制作所 | Parallel plate-type non-uniform electric field ionic mobility light-dividing device |
| CN107407658B (en) * | 2015-03-09 | 2020-08-07 | 株式会社岛津制作所 | Parallel-plate type non-uniform electric field ion mobility spectrometer |
| CN108091537B (en) * | 2016-11-21 | 2020-04-07 | 中国科学院大连化学物理研究所 | Step field ion migration tube |
| CN108091537A (en) * | 2016-11-21 | 2018-05-29 | 中国科学院大连化学物理研究所 | A kind of ladder Field ion mobility pipe |
| CN108878252A (en) * | 2018-07-02 | 2018-11-23 | 中国科学院电子学研究所 | Ion mobility spectrometry drift region multiplexer and method |
| CN110491766A (en) * | 2018-11-25 | 2019-11-22 | 中国科学院大连化学物理研究所 | A kind of direct current inhomogeneous field transference tube |
| CN111739784A (en) * | 2019-03-25 | 2020-10-02 | 哈米尔顿森德斯特兰德公司 | Ion source of ion mobility spectrometer |
| CN111739784B (en) * | 2019-03-25 | 2024-04-12 | 哈米尔顿森德斯特兰德公司 | Ion source of ion mobility spectrometer |
| CN110828281A (en) * | 2019-11-15 | 2020-02-21 | 中国科学院大连化学物理研究所 | Ion enrichment ion migration tube |
| CN111029241A (en) * | 2019-12-19 | 2020-04-17 | 中国科学院合肥物质科学研究院 | Ion mobility spectrometer and method for compensating ion mobility speed |
| CN112490108A (en) * | 2020-11-24 | 2021-03-12 | 中国科学院大连化学物理研究所 | Ion gate control method for automatically enriching ions |
| CN112490108B (en) * | 2020-11-24 | 2021-07-27 | 中国科学院大连化学物理研究所 | Ion gate control method for automatically enriching ions |
| CN114047245A (en) * | 2021-11-24 | 2022-02-15 | 中国科学院大连化学物理研究所 | Ion-molecule reaction selection control measuring device based on ion mobility spectrometry |
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Application publication date: 20130306 |