CN102950695B - 用于产生治疗性泡沫的装置和方法 - Google Patents
用于产生治疗性泡沫的装置和方法 Download PDFInfo
- Publication number
- CN102950695B CN102950695B CN201210320823.3A CN201210320823A CN102950695B CN 102950695 B CN102950695 B CN 102950695B CN 201210320823 A CN201210320823 A CN 201210320823A CN 102950695 B CN102950695 B CN 102950695B
- Authority
- CN
- China
- Prior art keywords
- chamber
- foam
- gas
- box
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000006260 foam Substances 0.000 title claims abstract description 139
- 230000001225 therapeutic effect Effects 0.000 title claims abstract description 13
- 238000004519 manufacturing process Methods 0.000 title description 7
- 239000007788 liquid Substances 0.000 claims abstract description 69
- 239000007789 gas Substances 0.000 claims description 89
- 239000000463 material Substances 0.000 claims description 25
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 20
- 230000008859 change Effects 0.000 claims description 14
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 10
- 239000001569 carbon dioxide Substances 0.000 claims description 10
- 239000008280 blood Substances 0.000 claims description 8
- 210000004369 blood Anatomy 0.000 claims description 8
- 125000004122 cyclic group Chemical group 0.000 claims description 8
- 229910052760 oxygen Inorganic materials 0.000 claims description 8
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 7
- 239000001301 oxygen Substances 0.000 claims description 7
- 239000012530 fluid Substances 0.000 claims description 5
- 230000035479 physiological effects, processes and functions Effects 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 19
- 229920001363 Polidocanol Polymers 0.000 abstract description 14
- ONJQDTZCDSESIW-UHFFFAOYSA-N polidocanol Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO ONJQDTZCDSESIW-UHFFFAOYSA-N 0.000 abstract description 14
- 229960002226 polidocanol Drugs 0.000 abstract description 14
- 230000002572 peristaltic effect Effects 0.000 abstract description 9
- 238000005086 pumping Methods 0.000 abstract description 9
- 239000008152 sclerosing solution Substances 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 49
- 229910052757 nitrogen Inorganic materials 0.000 description 24
- 238000005192 partition Methods 0.000 description 22
- 239000000243 solution Substances 0.000 description 12
- 230000004888 barrier function Effects 0.000 description 11
- 229920003023 plastic Polymers 0.000 description 11
- 239000004033 plastic Substances 0.000 description 11
- 229910052782 aluminium Inorganic materials 0.000 description 10
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 10
- 239000000203 mixture Substances 0.000 description 8
- -1 polypropylene Polymers 0.000 description 8
- 230000008569 process Effects 0.000 description 8
- 239000000284 extract Substances 0.000 description 7
- 239000004743 Polypropylene Substances 0.000 description 6
- 239000000853 adhesive Substances 0.000 description 6
- 230000001070 adhesive effect Effects 0.000 description 6
- 239000004411 aluminium Substances 0.000 description 6
- 230000008901 benefit Effects 0.000 description 6
- 239000011521 glass Substances 0.000 description 6
- 229920001903 high density polyethylene Polymers 0.000 description 6
- 239000004700 high-density polyethylene Substances 0.000 description 6
- 229920001155 polypropylene Polymers 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 5
- 239000002650 laminated plastic Substances 0.000 description 5
- 238000007789 sealing Methods 0.000 description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 238000005187 foaming Methods 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 238000003825 pressing Methods 0.000 description 4
- 229920002379 silicone rubber Polymers 0.000 description 4
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 3
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 3
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 3
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 3
- 230000000712 assembly Effects 0.000 description 3
- 238000000429 assembly Methods 0.000 description 3
- 238000005520 cutting process Methods 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 238000007632 sclerotherapy Methods 0.000 description 3
- 239000010703 silicon Substances 0.000 description 3
- 229910052710 silicon Inorganic materials 0.000 description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 2
- 150000001335 aliphatic alkanes Chemical class 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000013536 elastomeric material Substances 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 239000012744 reinforcing agent Substances 0.000 description 2
- 239000003229 sclerosing agent Substances 0.000 description 2
- 238000005245 sintering Methods 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 229910052724 xenon Inorganic materials 0.000 description 2
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 2
- 239000004604 Blowing Agent Substances 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
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- 239000003708 ampul Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 230000021615 conjugation Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- VDFAUQDYUFYDML-UHFFFAOYSA-L dihydroxy(dioxo)chromium propane-1,2,3-triol Chemical compound OCC(O)CO.[Cr](=O)(=O)(O)O VDFAUQDYUFYDML-UHFFFAOYSA-L 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- 238000011038 discontinuous diafiltration by volume reduction Methods 0.000 description 1
- GRIXGZQULWMCLU-UHFFFAOYSA-L disodium;7-[[2-carboxylato-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Chemical compound [Na+].[Na+].C12OCC(CSC=3N(N=NN=3)C)=C(C([O-])=O)N2C(=O)C1(OC)NC(=O)C(C([O-])=O)C1=CC=C(O)C=C1 GRIXGZQULWMCLU-UHFFFAOYSA-L 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- WBZKQQHYRPRKNJ-UHFFFAOYSA-L disulfite Chemical compound [O-]S(=O)S([O-])(=O)=O WBZKQQHYRPRKNJ-UHFFFAOYSA-L 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 229940031124 ethanolamine oleate Drugs 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- OJOSIIRLJDKIQK-UHFFFAOYSA-N iodic acid propane-1,2,3-triol Chemical compound OCC(O)CO.I(=O)(=O)O OJOSIIRLJDKIQK-UHFFFAOYSA-N 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000004005 microsphere Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000009928 pasteurization Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 238000007747 plating Methods 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 229920000260 silastic Polymers 0.000 description 1
- 229960005491 sodium morrhuate Drugs 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- GOLXNESZZPUPJE-UHFFFAOYSA-N spiromesifen Chemical compound CC1=CC(C)=CC(C)=C1C(C(O1)=O)=C(OC(=O)CC(C)(C)C)C11CCCC1 GOLXNESZZPUPJE-UHFFFAOYSA-N 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 201000009371 venous hemangioma Diseases 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/74—Mixing; Kneading using other mixers or combinations of mixers, e.g. of dissimilar mixers ; Plant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C44/00—Shaping by internal pressure generated in the material, e.g. swelling or foaming ; Producing porous or cellular expanded plastics articles
- B29C44/34—Auxiliary operations
- B29C44/3442—Mixing, kneading or conveying the foamable material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/235—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids for making foam
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/50—Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle
- B01F25/51—Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle in which the mixture is circulated through a set of tubes, e.g. with gradual introduction of a component into the circulating flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/74—Mixing; Kneading using other mixers or combinations of mixers, e.g. of dissimilar mixers ; Plant
- B29B7/7404—Mixing devices specially adapted for foamable substances
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/74—Mixing; Kneading using other mixers or combinations of mixers, e.g. of dissimilar mixers ; Plant
- B29B7/7404—Mixing devices specially adapted for foamable substances
- B29B7/7409—Mixing devices specially adapted for foamable substances with supply of gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/122—Foams; Dry foams
Landscapes
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Mechanical Engineering (AREA)
- Engineering & Computer Science (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Devices For Medical Bathing And Washing (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06026562.6 | 2006-12-21 | ||
| GB0625649A GB0625649D0 (en) | 2006-12-21 | 2006-12-21 | Method and apparatus for producing foam |
| EP06026562A EP1935605A1 (en) | 2006-12-21 | 2006-12-21 | Method and apparatus for producing foam |
| GB0625649.9 | 2006-12-21 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007800515913A Division CN101610889B (zh) | 2006-12-21 | 2007-12-21 | 用于产生治疗性泡沫的装置和方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102950695A CN102950695A (zh) | 2013-03-06 |
| CN102950695B true CN102950695B (zh) | 2015-05-27 |
Family
ID=39204700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210320823.3A Expired - Fee Related CN102950695B (zh) | 2006-12-21 | 2007-12-21 | 用于产生治疗性泡沫的装置和方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8235935B2 (enExample) |
| EP (2) | EP2452797A3 (enExample) |
| JP (1) | JP5069753B2 (enExample) |
| KR (1) | KR101547610B1 (enExample) |
| CN (1) | CN102950695B (enExample) |
| AU (1) | AU2007336023B2 (enExample) |
| CA (1) | CA2672834C (enExample) |
| CY (1) | CY1114009T1 (enExample) |
| DE (1) | DE112007003084T5 (enExample) |
| DK (1) | DK2125322T3 (enExample) |
| ES (1) | ES2402904T3 (enExample) |
| GB (1) | GB2456998B (enExample) |
| PL (1) | PL2125322T3 (enExample) |
| PT (1) | PT2125322E (enExample) |
| SI (1) | SI2125322T1 (enExample) |
| WO (1) | WO2008075080A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2461312C (en) * | 2001-09-24 | 2015-12-01 | Scott Laboratories, Inc. | Methods and apparatuses for assuring quality and safety of drug administration and medical products and kits |
| US9526846B2 (en) | 2009-08-19 | 2016-12-27 | Safety Syringes, Inc. | Patient-contact activated needle stick safety device |
| CN101870153B (zh) * | 2010-06-22 | 2012-12-19 | 青岛鑫三利冷箱技术有限公司 | 冷藏集装箱保温层小面积室外发泡预热夹持装置 |
| US9861736B2 (en) * | 2013-05-31 | 2018-01-09 | Fenwal, Inc. | Methods for extracting platelet-rich plasma for therapeutic injection |
| EP2962681A1 (en) * | 2014-07-03 | 2016-01-06 | Swiss VX Venentherapie und Forschung GmbH | Devices and methods for injectable vascular sclerofoams using a carrier made of human blood and uses thereof |
| EP3170549A1 (en) * | 2015-11-17 | 2017-05-24 | Enrique Roche Rebollo | Methods, devices, systems and kits for preparing compositions for care and repair of varicose veins |
| GB201611778D0 (en) | 2016-07-06 | 2016-08-17 | Provensis Ltd | Method and device for producing foam |
| GB201612925D0 (en) | 2016-07-26 | 2016-09-07 | Provensis Ltd | Method and device for generating injectable foam |
| FR3067910B1 (fr) * | 2017-06-23 | 2021-06-18 | Seb Sa | Appareil de fabrication d’un produit cosmetique personnalise |
| CA3103406A1 (en) | 2018-06-14 | 2019-12-19 | Curium Us Llc | Evacuation/fill station for radioactive fluid container production |
| CN112584919B (zh) * | 2018-08-21 | 2023-08-25 | 巴塞罗那血管设备有限责任公司 | 静脉曲张修复组合物的制备方法、装置、系统和试剂盒 |
| CN112454710B (zh) * | 2020-11-28 | 2022-06-10 | 深圳海源恒业高新材料科技研发有限公司 | 一种基于绿色环保的橡胶密炼加工设备 |
| DE102023112792A1 (de) * | 2023-05-15 | 2024-11-21 | Santa Isabel International Foundation | Mikroschaum-Generierungssystem mit Reaktionsbehälter, Kartusche und automatisierten System, Verfahren und Computerprogramm zum Erzeugen eines Mikroschaums |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1589306A (en) * | 1978-05-24 | 1981-05-13 | Grace W R Ltd | Method and apparatus for mixing polyurethane foam |
| CN2075540U (zh) * | 1990-08-04 | 1991-04-24 | 周长根 | 泡沫喷射立式发生装置 |
| CN1060041A (zh) * | 1991-10-24 | 1992-04-08 | 苏彦 | 气泡发生装置及其用途 |
| EP1647255A2 (en) * | 2004-10-13 | 2006-04-19 | Pentaferte Spa | Method for preparing sclerosing foams and medical device for implementing said method |
| EP2255889A2 (en) * | 2007-07-19 | 2010-12-01 | Nordson Corporation | Slot nozzle assembly, slot coating gun, shim plate, and method of extruding a foamable melted material in a wide band |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57206447A (en) * | 1981-06-12 | 1982-12-17 | Terumo Corp | Plastic container receiving liquid drug pasturized with high pressure steam and production thereof |
| EP0082465A1 (de) * | 1981-12-23 | 1983-06-29 | Ramisch Kleinewefers GmbH | Vorrichtung zum Zuführen von Schaum zu einem Abnehmer, z.B. einer Auftragsstation |
| US4411662A (en) * | 1982-04-06 | 1983-10-25 | Baxter Travenol Laboratories, Inc. | Sterile coupling |
| US5174285A (en) * | 1990-01-08 | 1992-12-29 | Lake Shore Medical Development Partners Ltd. | Localized heat transfer device |
| US5066428A (en) * | 1990-08-08 | 1991-11-19 | Rusmar Incorporated | Foam generating apparatus |
| ES2068151B1 (es) | 1993-06-23 | 1995-11-16 | Cabrera Garrido Juan | Microespuma inyectable para esclerosis. |
| GB9912356D0 (en) | 1999-05-26 | 1999-07-28 | Btg Int Ltd | Generation of microfoam |
| US6547063B1 (en) | 2000-10-10 | 2003-04-15 | The Procter & Gamble Company | Article for the delivery of foam products |
| DE50101401D1 (de) | 2001-06-11 | 2004-03-04 | Filtertek Bv | Kombinationsfilter-Anordnung |
| GB0300586D0 (en) | 2003-01-10 | 2003-02-12 | Btg Int Ltd | Therapeutic microfoam |
| AU2004290963A1 (en) * | 2003-11-17 | 2005-06-02 | Btg International Limited | Methods of preparing a foam comprising a sclerosing agent |
| GB0327957D0 (en) * | 2003-12-03 | 2004-01-07 | Btg Int Ltd | Apparatus for delivering foam |
| WO2006046202A1 (en) | 2004-10-29 | 2006-05-04 | Koninklijke Philips Electronics N.V. | Apparatus and methods for the production of ultrasound contrast agents |
| WO2006120469A2 (en) | 2005-05-13 | 2006-11-16 | Btg International Limited | Therapeutic sclerosing foam made preferably xenon |
| GB0509845D0 (en) * | 2005-05-13 | 2005-06-22 | Btg Int Ltd | Preparation of therapeutic foam |
| GB0509819D0 (en) | 2005-05-13 | 2005-06-22 | Btg Int Ltd | Therapeutic foam |
-
2007
- 2007-12-21 EP EP12154386.2A patent/EP2452797A3/en not_active Withdrawn
- 2007-12-21 ES ES07848667T patent/ES2402904T3/es active Active
- 2007-12-21 US US12/518,479 patent/US8235935B2/en active Active
- 2007-12-21 PT PT78486677T patent/PT2125322E/pt unknown
- 2007-12-21 SI SI200731234T patent/SI2125322T1/sl unknown
- 2007-12-21 AU AU2007336023A patent/AU2007336023B2/en not_active Ceased
- 2007-12-21 DE DE112007003084T patent/DE112007003084T5/de not_active Withdrawn
- 2007-12-21 GB GB0910182A patent/GB2456998B/en not_active Expired - Fee Related
- 2007-12-21 KR KR1020097015338A patent/KR101547610B1/ko not_active Expired - Fee Related
- 2007-12-21 PL PL07848667T patent/PL2125322T3/pl unknown
- 2007-12-21 EP EP07848667A patent/EP2125322B1/en not_active Not-in-force
- 2007-12-21 CN CN201210320823.3A patent/CN102950695B/zh not_active Expired - Fee Related
- 2007-12-21 DK DK07848667.7T patent/DK2125322T3/da active
- 2007-12-21 JP JP2009542224A patent/JP5069753B2/ja not_active Expired - Fee Related
- 2007-12-21 CA CA2672834A patent/CA2672834C/en not_active Expired - Fee Related
- 2007-12-21 WO PCT/GB2007/004943 patent/WO2008075080A1/en not_active Ceased
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2012
- 2012-07-09 US US13/544,984 patent/US8517975B2/en not_active Expired - Fee Related
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2013
- 2013-05-29 CY CY20131100422T patent/CY1114009T1/el unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1589306A (en) * | 1978-05-24 | 1981-05-13 | Grace W R Ltd | Method and apparatus for mixing polyurethane foam |
| CN2075540U (zh) * | 1990-08-04 | 1991-04-24 | 周长根 | 泡沫喷射立式发生装置 |
| CN1060041A (zh) * | 1991-10-24 | 1992-04-08 | 苏彦 | 气泡发生装置及其用途 |
| EP1647255A2 (en) * | 2004-10-13 | 2006-04-19 | Pentaferte Spa | Method for preparing sclerosing foams and medical device for implementing said method |
| EP2255889A2 (en) * | 2007-07-19 | 2010-12-01 | Nordson Corporation | Slot nozzle assembly, slot coating gun, shim plate, and method of extruding a foamable melted material in a wide band |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5069753B2 (ja) | 2012-11-07 |
| PL2125322T3 (pl) | 2013-08-30 |
| GB0910182D0 (en) | 2009-07-29 |
| CY1114009T1 (el) | 2016-07-27 |
| HK1137164A1 (en) | 2010-07-23 |
| DE112007003084T5 (de) | 2009-10-29 |
| HK1182994A1 (en) | 2013-12-13 |
| US8235935B2 (en) | 2012-08-07 |
| US20120273977A1 (en) | 2012-11-01 |
| GB2456998B (en) | 2011-09-28 |
| KR20090102820A (ko) | 2009-09-30 |
| CN102950695A (zh) | 2013-03-06 |
| EP2125322A1 (en) | 2009-12-02 |
| ES2402904T3 (es) | 2013-05-10 |
| KR101547610B1 (ko) | 2015-08-26 |
| EP2125322B1 (en) | 2013-03-06 |
| CA2672834A1 (en) | 2008-06-26 |
| JP2010512899A (ja) | 2010-04-30 |
| AU2007336023B2 (en) | 2013-07-04 |
| US8517975B2 (en) | 2013-08-27 |
| CA2672834C (en) | 2015-04-21 |
| GB2456998A (en) | 2009-08-05 |
| WO2008075080A1 (en) | 2008-06-26 |
| EP2452797A2 (en) | 2012-05-16 |
| PT2125322E (pt) | 2013-06-04 |
| AU2007336023A1 (en) | 2008-06-26 |
| DK2125322T3 (da) | 2013-04-02 |
| SI2125322T1 (sl) | 2013-07-31 |
| US20100099778A1 (en) | 2010-04-22 |
| EP2452797A3 (en) | 2013-10-09 |
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