CN102911076B - Treatment unit after acetparaminosalol phenol treating and treatment process thereof - Google Patents
Treatment unit after acetparaminosalol phenol treating and treatment process thereof Download PDFInfo
- Publication number
- CN102911076B CN102911076B CN201210441026.0A CN201210441026A CN102911076B CN 102911076 B CN102911076 B CN 102911076B CN 201210441026 A CN201210441026 A CN 201210441026A CN 102911076 B CN102911076 B CN 102911076B
- Authority
- CN
- China
- Prior art keywords
- loading device
- fluidized bed
- vibrated fluidized
- feed tank
- lower discharging
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Disintegrating Or Milling (AREA)
- Crushing And Grinding (AREA)
Abstract
The invention provides the treatment unit after a kind of acetparaminosalol phenol treating and treatment process thereof.This treatment unit comprises: be connected with the outlet of crystallizer, receive and stir the feed tank of the material from described crystallizer output; The lower discharging centrifuge be connected with the outlet of described feed tank; Be arranged at the loading device below described lower discharging centrifuge, described lower discharging centrifuge by the material discharging after centrifugal to described loading device; Be connected with described loading device, dry vibrated fluidized bed is carried out to the material from institute's loading device; And be connected with described vibrated fluidized bed, the pulverizer that the material introduced the vibration by described vibrated fluidized bed is pulverized.Treatment unit of the present invention and treatment process achieve continuous prodution, reach the requirement of cleaner production, avoid crossed contamination, again reduce the labour intensity of workman, save artificial, and improve the batch of finished product, decrease laboratory fee and use.
Description
Technical field
The present invention relates to the devices and methods therefor in a kind of paracetamol production process, the treatment unit particularly after a kind of acetparaminosalol phenol treating and treatment process thereof.
Background technology
In the production treating process of current paracetamol, because the output of paracetamol is general all larger, often more than one, refining crystallization tank, but multiple, in traditional mode, the material of refining crystallization is after multiple little whizzer dries, load in truck, be transported to drying plant by workman again and carry out drying through artificial loading, dried material reinstalls truck and is transported to pulverizer place and is pulverized by artificial loading, then packs.The labour intensity of workman is large in the process, and can not non-stop run, and the dust environmental pollution of dried material is very large, can not reach the requirement of cleaner production, and crossed contamination is inevitable.
Moreover the finished product batch that single refining crystallization tank goes out is smaller, and will chemically examine separately the finished product that each refining crystallization tank goes out, due to the quantity generally more than one but multiple of refining crystallization tank, cause chemical examination so often, costly, thus cost is not easy to control.
Summary of the invention
The object of the invention is to overcome above-mentioned technical problem, treatment unit after a kind of acetparaminosalol phenol treating and treatment process thereof are provided, the present invention passes through the improvement of equipment and the optimization of flow process, achieve continuous prodution, reach the requirement of cleaner production, avoid crossed contamination, again reduce the labour intensity of workman, save artificial, and improve the batch of finished product, decrease laboratory fee and use.
Treatment unit after acetparaminosalol phenol treating provided by the invention, comprising:
Be connected with the outlet of crystallizer, receive and stir the feed tank of the material from described crystallizer output;
The lower discharging centrifuge be connected with the outlet of described feed tank;
Be arranged at the loading device below described lower discharging centrifuge, described lower discharging centrifuge by the material discharging after centrifugal to described loading device;
Be connected with described loading device, dry vibrated fluidized bed is carried out to the material from institute's loading device; And
Be connected with described vibrated fluidized bed, the pulverizer that the material introduced the vibration by described vibrated fluidized bed is pulverized.
Material in described crystallizer can by being pumped into feed tank.
Described loading device and described vibrated fluidized bed can be connected by the seal for pipe joints be arranged on above described loading device.Flexible pipe such as can be used to be tightly connected.
Described vibrated fluidized bed and described pulverizer can be tightly connected, and are tightly connected by stainless steel tube.Be tightly connected and can reduce crossed contamination, reach the requirement of cleaner production.
Described crystallizer is at least two, and the number of crystallizer can be determined according to the volume of feed tank.Such as when the volume of feed tank is 2.4 times of crystallizer volume, crystallizer can be two, and the material after can simultaneously being refined by two crystallizers is introduced in feed tank, thus increases the batch of product.
Described lower discharging centrifuge is manual or full automatic, and the present invention is preferably full-automatic scraper lower discharging centrifuge.
The present invention can utilize vacuum by vibrated fluidized bed described in the material suction on described loading device.Such as vaccum-pumping equipment is set between described vibrated fluidized bed and described loading device.
Described loading device can select conventional truck etc.
Treatment process after acetparaminosalol phenol treating provided by the invention, have employed above-mentioned treatment unit, comprises following operation steps:
Material after at least one crystallizer refining crystallization is squeezed into the step of feed tank by pump;
Carry out the stirring of described material in described feed tank after, by lower discharging centrifuge, centrifugal and discharging is to the step of the loading device be arranged on below described lower discharging centrifuge;
By vacuum the material in described loading device is extracted on vibrated fluidized bed and carries out drying, utilize the shake of described vibrated fluidized bed by the step of described mass transport to pulverizer afterwards;
Material powders after being pulverized by described pulverizer is transported to the step that packaging process carries out packing.
Beneficial effect of the present invention: the arrangement achieves non-stop run, between the some treatment process after acetparaminosalol phenol treating need not hand charging, the operation such as material loading and transport, greatly reduce the labour intensity of workman; In addition, this device adopts the interconnecting piece of sealing be connected with pulverizer by drying plant thus avoid the pollution of dried material dust to environment, makes it reach the requirement of cleaner production, but also avoids crossed contamination.In addition, in this device, introduce this equipment of feed tank, the material in multiple crystallizer can be made just to be mixed into before centrifugation a collection of, thus increase the batch of finished product, also equal to eliminate corresponding mixed batch machine, chemically examine number of times simultaneously and tail off, expense reduces, thus reduces production cost.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the treatment unit after the acetparaminosalol phenol treating in the preferred embodiments of the present invention.
Fig. 2 is the structural representation of the mixed batch machine that prior art adopts.
Wherein, description of reference numerals is as follows:
1: crystallizer; 2: feed tank; 3: full-automatic scraper lower discharging centrifuge; 4: truck; 41: flexible pipe; 5: vibrated fluidized bed; 51: stainless steel tube; 6: pulverizer.
Embodiment
Below in conjunction with accompanying drawing, the treatment unit after acetparaminosalol phenol treating of the present invention and treatment process thereof are described.
First, the treatment unit after the acetparaminosalol phenol treating in the preferred embodiment of the present invention is described.
Fig. 1 is the schematic diagram of the treatment unit after the acetparaminosalol phenol treating in the preferred embodiment of the present invention.
As shown in Figure 1, the treatment unit after the acetparaminosalol phenol treating in this preferred embodiment, comprising: be connected with the outlet of one or more crystallizer 1, receives and stirs the feed tank 2 of the material from described crystallizer 1 output; The unloading under scraper whizzer 3 be connected with the outlet of described feed tank 2; Be arranged at the truck 4 of the below of described unloading under scraper whizzer 3, described unloading under scraper whizzer 3 is by the material discharging of described feed tank 2 extremely described truck 4; Vibrated fluidized bed 5, is connected with described truck 4, utilizes vacuum by the material suction of 4 li, described truck, carries out drying; Pulverizer 6, is connected with described vibrated fluidized bed 5, by the vibration of described vibrated fluidized bed 5, material is at the uniform velocity introduced pulverizer 6, then pulverizes material, and the material after finally pulverizing pulverizer is again packed, chemically examined.
The mode that material enters feed tank 2 from crystallizer 1 can be admitted to feed tank 2 under the effect of pump, also can be other feasible modes.As unloading under scraper whizzer, full-automatic model can be adopted, also can to adopt manual model, determine according to actual needs.
In addition, described truck 4 and described vibrated fluidized bed 5 are connected by the seal for pipe joints be arranged on above described truck 4, connects preferably through flexible pipe 41.Why adopting sealing-duct, is because will by vacuum the material suction vibrated fluidized bed 5 on truck 4.For this reason, needing, vaccum-pumping equipment is set between truck 4 and vibrated fluidized bed and is connected with above-mentioned pipeline, facilitate the use vacuum convey materials between truck 4 and vibration vulcanization bed 5.
Certainly, if the draft of blower fan is enough large, also can utilize blower fan that material is transported to vibrated fluidized bed 5 from truck 4.
In addition, described vibrated fluidized bed 5 is tightly connected by stainless steel tube 51 with the connection of described pulverizer 6, thus avoids the pollution of dried material dust to environment, makes it reach the requirement of cleaner production, but also avoids crossed contamination.
Described crystallizer 1 is not limited to one, can be multiple, be provided with two crystallizers in the present embodiment.When crystallizer is two or more, that is when the material of multiple crystallizer output is all incorporated in feed tank 2, feed tank is just equivalent to a transfer tank, the material of multiple crystallizer output can be carried out mixing thus becoming a collection of wherein, the batch of such finished product becomes large, also save laboratory fee while eliminating a mixed batch machine to use, if process the paracetamol after refining in a traditional way, the finished product that each refining crystallization tank goes out to be chemically examined separately, and adopt treatment unit of the present invention, due to the material that multiple refining crystallization tank is gone out first carry out mixing carry out again centrifugal, dry, pulverization process, decrease need chemical examination batch, add the quantum of output of each batch, use so reduce laboratory fee.
Detailed analysis the present invention once below adopts feed tank to carry out mixing of materials and mixes compared to adopting in prior art the advantage that batch machine carries out mixing of materials.
At the mixed batch machine that utilizes below of centrifugal, drying process (namely at vibrated fluidized bed 5) etc., the material that different batches is produced is mixed in prior art, the structural representation of mixed batch machine as shown in Figure 2, exactly diconical stainless steel tank body is placed on a large support, dried material is placed on the inside, then lid is built, utilize transmission of crankshaft to move back and forth, thus the dried material putting into tank body is mixed.
The present invention adopts and directly use feed tank 2 by the mixing of materials of different batches together after multiple crystallizer 1, then after being uniformly mixed, carries out the operations such as centrifugal, dry again.
The prior art adopting mixed batch machine mixes the material of drying, owing to being again make material reach mixed uniformly by this mode of putting upside down back and forth of tank body, produce a large amount of dust between dry material (near causing the working district of mixed batch machine, dust increases because of friction, and during packaging, dust also can increase, and brings detrimentally affect thus to the Working environment of operating personnel).
And feed tank of the present invention is owing to being the material directly received from crystallizer, and material is now liquid, and be by the mode (being provided with agitator in tank body) of stirring, the object in tank is mixed, so decrease the generation of dust, improve the operating environment of workman.
And the effect stirred, be uniformly mixed comparison mix from the solid of different batches the liquid from different batches (crystallizer), the former effect of mixing should be better, namely mixing evenly.
And compared with feed tank, the mixed batch of machine is not only expensive but also need the place of larger area, so adopt the mode of feed tank both to provide cost savings the requirement again reduced place.The treatment unit in the preferred embodiment of the present invention is adopted to be described the treatment process after acetparaminosalol phenol treating below.
Material after two crystallizer 1 refining crystallizations is squeezed into 2.4 times that its volume of described feed tank 2(is equivalent to crystallizer 1 volume through a pump), material stirring is carried out in described feed tank 2, afterwards, by described full-automatic scraper lower discharging centrifuge 3 centrifugal, (effect of whizzer is exactly the effect playing solid-liquid separation, because common link-suspended basket centrifuge needs artificial from top discharging, so in order to reduce labor strength, the whizzer that this place adopts is full automatic, do not need artificial, and can bottom discharge automatically) and automatic discharging to the described truck 4 arranged thereunder, then by vacuum, the material in described truck 4 is extracted into described vibrated fluidized bed 5 to carry out drying and (why directly the material after centrifugal for whizzer 3 will not sent into fluidized-bed 5 through truck 4, because the material in feed tank 2 can not disposablely get rid of, need just can get rid of several times, if directly discharging enters fluidized-bed, the work of serialization can not be ensured), the shake of described vibrated fluidized bed 5 is utilized material to be at the uniform velocity transported to described pulverizer 6 afterwards, finally pack being transported to packing department by the material powders after described pulverizer pulverizing.
Claims (5)
1. the treatment unit after acetparaminosalol phenol treating, is characterized in that, comprising:
Be connected with the outlet of at least two crystallizers, receive and stir the feed tank of the material from described at least two crystallizer outputs; Agitator is provided with in the tank body of described feed tank;
The lower discharging centrifuge be connected with the outlet of described feed tank;
Be arranged at the loading device below described lower discharging centrifuge, described lower discharging centrifuge by the material discharging after centrifugal to described loading device;
Be connected with described loading device, dry vibrated fluidized bed is carried out to the material from institute's loading device; And
Be connected with described vibrated fluidized bed, the pulverizer that the material introduced the vibration by described vibrated fluidized bed is pulverized,
Described material utilizes pump to squeeze into described feed tank from described at least two crystallizers;
Described loading device and described vibrated fluidized bed are connected by the seal for pipe joints be arranged on above described loading device;
Material on described loading device utilizes vacuum to be pumped on described vibrated fluidized bed.
2. the treatment unit after acetparaminosalol phenol treating as claimed in claim 1, is characterized in that,
Described vibrated fluidized bed and described pulverizer are tightly connected.
3. the treatment unit after acetparaminosalol phenol treating as claimed in claim 1, is characterized in that,
Described lower discharging centrifuge is full-automatic scraper lower discharging centrifuge.
4. the treatment process after acetparaminosalol phenol treating, is characterized in that, comprises following operation steps:
Material after at least two crystallizer refining crystallizations is squeezed into the step of feed tank by pump;
Carry out the stirring of described material in described feed tank after, by lower discharging centrifuge, centrifugal and discharging is to the step of the loading device be arranged on below described lower discharging centrifuge; Agitator is provided with in the tank body of described feed tank;
By vacuum the material in described loading device is extracted on vibrated fluidized bed and carries out drying, utilize the shake of described vibrated fluidized bed by the step of described mass transport to pulverizer afterwards;
Material powders after being pulverized by described pulverizer is transported to the step that packaging process carries out packing.
5. the treatment process after acetparaminosalol phenol treating as claimed in claim 4, is characterized in that,
Described lower discharging centrifuge is full-automatic scraper lower discharging centrifuge.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210441026.0A CN102911076B (en) | 2012-11-07 | 2012-11-07 | Treatment unit after acetparaminosalol phenol treating and treatment process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210441026.0A CN102911076B (en) | 2012-11-07 | 2012-11-07 | Treatment unit after acetparaminosalol phenol treating and treatment process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102911076A CN102911076A (en) | 2013-02-06 |
| CN102911076B true CN102911076B (en) | 2015-09-02 |
Family
ID=47609682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210441026.0A Active CN102911076B (en) | 2012-11-07 | 2012-11-07 | Treatment unit after acetparaminosalol phenol treating and treatment process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102911076B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86102837A (en) * | 1986-02-20 | 1987-09-02 | 药品管理公司 | Preparation of stable crystal of sodium acetylsalicylate |
| US20040176233A1 (en) * | 2001-07-19 | 2004-09-09 | Ernst-Ulrich Himmen | Deviation ring for a self-distributing centrifuge |
| CN102382004A (en) * | 2011-08-19 | 2012-03-21 | 河北冀衡（集团）药业有限公司 | Decolorization pre-treatment system and decolorization pre-treatment method of acetaminophen |
| CN202290321U (en) * | 2011-10-20 | 2012-07-04 | 河北冀衡（集团）药业有限公司 | Closed material throwing system for acetaminophen production |
| CN202387546U (en) * | 2012-01-09 | 2012-08-22 | 河北冀衡（集团）药业有限公司 | Device for controlling grain size of paracetamol powder |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102030712B (en) * | 2010-11-18 | 2012-02-01 | 大庆井井源油田科技开发有限公司 | Device for producing dimethyl hydantoin |
-
2012
- 2012-11-07 CN CN201210441026.0A patent/CN102911076B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86102837A (en) * | 1986-02-20 | 1987-09-02 | 药品管理公司 | Preparation of stable crystal of sodium acetylsalicylate |
| US20040176233A1 (en) * | 2001-07-19 | 2004-09-09 | Ernst-Ulrich Himmen | Deviation ring for a self-distributing centrifuge |
| CN102382004A (en) * | 2011-08-19 | 2012-03-21 | 河北冀衡（集团）药业有限公司 | Decolorization pre-treatment system and decolorization pre-treatment method of acetaminophen |
| CN202290321U (en) * | 2011-10-20 | 2012-07-04 | 河北冀衡（集团）药业有限公司 | Closed material throwing system for acetaminophen production |
| CN202387546U (en) * | 2012-01-09 | 2012-08-22 | 河北冀衡（集团）药业有限公司 | Device for controlling grain size of paracetamol powder |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102911076A (en) | 2013-02-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103340171A (en) | Intelligent feeding device for aquaculture | |
| CN208882221U (en) | Production system of organic matter fertilizer | |
| CN207856767U (en) | A kind of efficient chemical industry device for mixing raw material | |
| CN206027542U (en) | Storage bin is delayed in stirring | |
| CN213557402U (en) | Carbon black powder granulation system | |
| CN203183952U (en) | Powder mixing machine | |
| CN209501511U (en) | A kind of feed processing production agitating device | |
| CN202492466U (en) | Automatic organic fertilizer production line | |
| CN102911076B (en) | Treatment unit after acetparaminosalol phenol treating and treatment process thereof | |
| CN206520111U (en) | A kind of polyvinyl chloride powder burden agitator | |
| CN210846258U (en) | Full-automatic feeding and stirring system for batteries | |
| CN209362251U (en) | A kind of lepidolite ingredient agitating device | |
| CN204583020U (en) | Heat-conducting oil heating mixer | |
| CN202898274U (en) | Device for treatment after acetaminophen refining | |
| CN107226354A (en) | Weigh charging equipment and its application method of a kind of technique of saltouing | |
| CN208720231U (en) | A kind of rotary kiln multipurpose solid powder add-on system | |
| CN206810161U (en) | A kind of powdered chemical raw material mixing device | |
| CN202876725U (en) | V-shaped mixer | |
| CN206033768U (en) | Mixed type microbial inoculant production line | |
| CN204779387U (en) | Fertile system of system with good oxygen stirring function of wall is scraped in rotation of heating cloth oxygen | |
| CN210279430U (en) | Ball-milling, bipyramid blendor, automatic alignment and vacuum feeding integration equipment | |
| CN107497314A (en) | A kind of mixer for being easy to cleaning | |
| CN211070020U (en) | Powder mixing and stirring system | |
| CN211612580U (en) | Automatic blanking device of agricultural machine | |
| CN209576630U (en) | A kind of reaction kettle feeding system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address |
Address after: 053000 No.1, Weiwu street, high tech Zone, Hengshui City, Hebei Province Patentee after: Hebei Jiheng Pharmaceutical Co.,Ltd. Address before: 053000 No.368 Jianshe North Street, Hengshui City, Hebei Province Patentee before: HEBEI JIHENG (Group) PHARMACEUTICAL Co.,Ltd. |
|
| CP03 | Change of name, title or address |