CN102895129A - Composition for smoothing out wrinkles on skin and firming skin - Google Patents
Composition for smoothing out wrinkles on skin and firming skin Download PDFInfo
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- CN102895129A CN102895129A CN2012104595708A CN201210459570A CN102895129A CN 102895129 A CN102895129 A CN 102895129A CN 2012104595708 A CN2012104595708 A CN 2012104595708A CN 201210459570 A CN201210459570 A CN 201210459570A CN 102895129 A CN102895129 A CN 102895129A
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Abstract
The invention discloses a composition for smoothing out wrinkles on the skin and firming the skin, and aims to provide a composition (SOPC-H for short) which can effectively clear away free radicals produced by the skin of a human body, improves the activity of elastic collagen in the skin, firms the skin and improves the elasticity of the skin. The composition is characterized by consisting of the following components in percentage by weight: 30-70 percent of super procyanidins and 30-70 percent of hydrolyzed hazelnut protein. The composition belongs to the technical field of skin care products.
Description
Technical field
The present invention discloses a kind of compositions (be called for short SOPC-H), specifically, is a kind of compositions of compacting for the skin plain weave, belongs to technical field of skin care.
Background technology
The reason of skin aging has: (1) intrinsic factor, heredity, neuroendocrine system and dermis thickness etc.(2) extrinsic factor 1. excessive ultraviolet radiation can destroy elastic fiber and the collagen fiber of corium, make fiber fracture occur, cutis laxa, wrinkle appears.2. skin pore blocks, and affects fat secretion and exchange of moisture, causes xerosis cutis, wrinkle, acne, freckle.When (3) vivotoxin was drained in the situation body cisco unity malfunction such as toxin expelling organ such as intestinal, kidney, lung, toxin can not in time excrete out, and will come toxin expelling by skin, acne, skin allergy, long speckle occur.(4) nutrient in the maintenance body of the nutriture of human body and skin at first is to guarantee the after one's own heart supply of Liver and kidney brain lung of life-critical organ, and unnecessary nutrient offers the uses such as non-vital organ such as skin again.The human nutrition situation is poor, when nutrient is not enough, the nutrition of skin often can not be guaranteed.As not noting the inherent and external maintenance of skin, also can accelerate the aging of skin at ordinary times.
The performance of skin aging is thinning of skin, and is lax, and sebum secretion reduces, xerosis cutis, coarse, wrinkle, long speckle.The people is to after 25 years old, and the production capacity of elastin laminin just begins to die down, and the elastin laminin in the skin is just constantly passage also, and skin begins to relax, has the catabiosis such as microgroove.So the plain weave that compacts, increasing skin elasticity is one of main means that resist skin aging.
Skin care item and clean skin product are one of the article of everyday use that must use every day of modern female.Chinese women likes skin-tightening level and smooth, and most of women is the product of the wrinkle of using over, the skin that compacts.And a part of women also can use and claim special skin care item or the skin-cleaning articles that contain medical components because of pachylosis, lax and other reasons, and safety causes anxiety.
Summary of the invention
The present invention utilizes the combination of super procyanidin (SOPC) and hydrolysis hazelnut albumen, strengthens removing the free radical that human body skin produces, and strengthens the activity of skin Elastic collagen protein, reaches the skin that compacts, and significantly increases the effect of skin elasticity.
Technical scheme of the present invention is such: should be used for the compositions that the skin plain weave compacts, be made of the component of following quality than component: the hydrolysis hazelnut albumen of the super procyanidin of 30%-70% and 30%-70%, each component sum is 100%.
Above-mentioned be used for the compositions that the skin plain weave compacts, the following quality of said composition consists of than the component of component: the hydrolysis hazelnut albumen of the super procyanidin of 40%-60% and 40%-60%, each component sum is 100%.
Above-mentioned be used for the compositions that the skin plain weave compacts, described super procyanidin extracts from French malaga, is a kind of oligomer procyanidin, and structural formula is formula 1:
Formula 1
Above-mentioned be used for the compositions that the skin plain weave compacts, described hydrolysis hazelnut protein CAS is numbered 100209-45-8.
Compared with prior art, compositions provided by the invention to free radical resisting, avoids collagen protein and elasticity collagen protein in the skin to come to harm by SOPC, and opposing is old and feeble, suppresses the appearance of microgroove; Synthesizing of hydrolysis hazelnut albumen stimulation collagen and elasticity collagen protein improved the protein content in the skin, keeps skin health flexible, resist skin aging, prevent loosely, improve skin elasticity, level and smooth microgroove effect is remarkable, and both scientific composition have the effect of the skin that well compacts.
The specific embodiment
Below in conjunction with the specific embodiment, technical scheme of the present invention is described in further detail, but does not consist of any limitation of the invention.
Embodiment 1
Take by weighing super procyanidin (SOPC) powder 10g, place the 250mL beaker, add the 90g distilled water, stir, until fully dissolving.With middle density filter paper filtering, obtain the SOPC solution of clear, temporary for subsequent use.
Take by weighing hydrolysis hazelnut protein 10 g, place the 250mL beaker, add the 90g distilled water, stir, until fully dissolving.With middle density filter paper filtering, obtain milky hydrolysis hazelnut protein solution, temporary for subsequent use.Wherein, hydrolysis hazelnut albumen is provided by French SOLABIA
Get SOPC solution 30g and directly mix with hydrolysis hazelnut protein solution 70g, obtain the super procyanidin (SOPC) of 30%:70%/hydrolysis hazelnut protein composition (SOPC-H), solid content is 10%.
Embodiment 2
Take by weighing super procyanidin (SOPC) powder 10g, place the 250mL beaker, add the 90g distilled water, stir, until fully dissolving.With middle density filter paper filtering, obtain the SOPC solution of clear, temporary for subsequent use.
Take by weighing hydrolysis hazelnut protein 10 g, place the 250mL beaker, add the 90g distilled water, stir, until fully dissolving.With middle density filter paper filtering, obtain the hydrolysis hazelnut protein solution of clear, temporary for subsequent use.
Get SOPC solution 40g and directly mix with hydrolysis hazelnut protein solution 60g, obtain the super procyanidin (SOPC) of 40%:60%/hydrolysis hazelnut protein composition (SOPC-H), solid content is 10%.
Embodiment 3
Take by weighing super procyanidin (SOPC) powder 20g, place the 250mL beaker.Take by weighing again hydrolysis hazelnut protein 20 g, join in the same beaker.In beaker, add the 60g distilled water, stir, until fully dissolving.With middle density filter paper filtering, obtain milky super procyanidin (SOPC)/hydrolysis hazelnut protein composition (SOPC-H), solid content is 10%, wherein the ratio of two kinds of materials is 50%:50%.
Embodiment 4
Take by weighing super procyanidin (SOPC) powder 10g, place the 250mL beaker, add the 90g distilled water, stir, until fully dissolving.With middle density filter paper filtering, obtain the SOPC solution of clear, temporary for subsequent use.
Take by weighing hydrolysis hazelnut protein 10 g, place the 250mL beaker, add the 90g distilled water, stir, until fully dissolving.With middle density filter paper filtering, obtain the hydrolysis hazelnut protein solution of clear, temporary for subsequent use.
Get SOPC solution 60g and directly mix with hydrolysis hazelnut protein solution 40g, obtain the super procyanidin (SOPC) of 60%:40%/hydrolysis hazelnut protein composition (SOPC-H), solid content is 10%.
Embodiment 5
Take by weighing super procyanidin (SOPC) powder 10g, place the 250mL beaker, add the 90g distilled water, stir, until fully dissolving.With middle density filter paper filtering, obtain the SOPC solution of clear, temporary for subsequent use.
Take by weighing hydrolysis hazelnut protein 10 g, place the 250mL beaker, add the 90g distilled water, stir, until fully dissolving.With middle density filter paper filtering, obtain the hydrolysis hazelnut protein solution of clear, temporary for subsequent use.
Get SOPC solution 70g and directly mix with hydrolysis hazelnut protein solution 30g, obtain the super procyanidin (SOPC) of 70%:30%/hydrolysis hazelnut protein composition (SOPC-H), solid content is 10%.
This SOPC-H can be used as the skin plain weave active matter that compacts, and is used for preparation cream frost emulsion class skin care item.
When specifically using, room temperature adds in the SOPC-L compositions and basic emulsion of 1-5%, and emulsifying is even.
The preparation basic emulsion, fill a prescription such as following table 1:
Table 1
Compound method: the A heat phase is to 80-85 ℃, and the B heat phase is to 80-85 ℃, and A is added to the B phase, and emulsifying homogeneous is even.Be cooled to 45 ℃ under the stirring, add the C phase, homogenizing is even, as basic emulsion.
Principle of the present invention:
Super procyanidin is to extract to obtain material from French VITIS VINIFERA Fructus Vitis viniferae, English name is Super Oligomeric Proantho Cyanidins(SOPC), being a kind of oligomer procyanidin that special molecular structure is arranged, is a kind of of the most effective Natural antioxidant procyanidin of free radical OPC in the removing human body of generally acknowledging in the world at present.Super procyanidin (SOPC) is a kind of high-efficiency antioxidant agent, is the most potent free radical scavenger of finding so far, has very strong activity in vivo.
Hydrolysis hazelnut albumen is the hydrolysis hazelnut oligopeptide of high bioactivity and aminoacid etc., promotes the horn cell breeding, promotes the fibroblast breeding, promotes cell metabolism, promotes the synthetic of collagen.Use can the recombinate effect of sebum barrier of hydrolysis hazelnut albumen, promote the synthetic of epidermis sebum.
(2) select suitable hydrolysis hazelnut albumen as raw material.The hydrolysis hazelnut albumen of choice for use of the present invention is provided by French SOLABIA company, and wherein hazelnut derives from hazel tree.Hazel tree is machaka, and hermaphroditism, fruit are filbert hazelnut or Semen coryli heterophyllae, and shell is hard, edible.It contains abundant vitamin B1, B2, C, E, protein and carbohydrate.In per 100 gram Semen coryli heterophyllaes, contain 618 milligrams potassium, 354 milligrams phosphorus, 287 milligrams calcium, 46 milligrams thiamine also has the mineral such as niacin and ferrum.The hydrolysis crylin is rich in aminoacid, contracting amino acid (glutamic acid, arginine, aspartic acid and praline) and glucose, galactose etc.
Hydrolysis hazelnut protein I NCI name: hydrolysis hazelnut albumen
CAS number: 100209-45-8
The PH(potentiometry) 5.0-7.0
Dry extract (100-105 ℃, 4 hours) 55 ± 10g/L
Total nitrogen content (Kjeldahl): 4 ± 1g/L
Nitrogen content in the amino (Soerensen): 0.9 ± 0.4g/L
Total glucides content (phynol method): 13 ± 4g/L
The compact mechanism of action of skin of the present invention is: super procyanidin (SOPC) can exchange an electronics with free radical, and the free radical of removing with wish has approximate oxidation-reduction potential, and electronics is stablized by delocalization in the chemical compound of generation.Because on the SOPC a plurality of phenolic hydroxyl groups are arranged, they can be combined with living radical, generate stable chemical compound.The snperoxiaized metal ion of SOPC chelating participates in the antioxidative synergism, by stopping free chain reaction, Scavenger of ROS, the detrimental effect of elimination radical pair body tissue and organ.Therefore SOPC can keep the young attitude of skin, reduces wrinkle of skin.And the main component of hydrolysis hazelnut albumen is oligopeptide and the aminoacid of high bioactivity, has the promotion cell metabolism, accelerates the synthetic of collagen.Both are used in combination, and cooperatively interact from inside to outside, and coordinative role reaches the significant plain weave skin effect that compacts.
Experimental example 1
Choosing 10 canthus has the volunteer of crows-feet, one group of two people, being divided into 5 groups tries out, smear the emulsion that contains among the embodiment 1 to 5, smear every day twice as follows, 1 Zhou Houhui produces effect, canthus microgrooves obviously shoal after 2 weeks, the deep layer stricture of vagina also obviously shoals after 4 weeks, and wherein the user effect of 50%:50% solution is the most obvious.
Experimental example 2
SOPC-H improves old and feeble sign experiment
The emulsion that contains SOPC-H2% is improved old and feeble sign experiment (SOPC quality: hydrolysis hazelnut albumen quality=1:1)
Experimental design:
42 volunteers' skin plain weave clinical trial;
2%SOPC-H emulsion and blank formula contrast;
Compositions is to use twice every day, uses continuously for 8 weeks, the test of half face;
Had nurse one's health the phase in advance in three days before the experiment beginning, do benchmark after three days and measure;
Do the digital image analysis of silica gel pour mask for the wrinkle of surveying outside the canthus; Super close-up photography is done microgroove and fold evaluation
CUTOMETER measures skin elasticity.After 8 weeks, contrast with blank formula, (the SOPC quality: the emulsion of hydrolysis hazelnut albumen quality=1:1) has every effect of improving, and the silica gel pour mask of the outside, canthus wrinkle is analyzed show that the prescription that contains 2%SOPC-H has the effect of improving the skin smooth degree to contain quality 2%SOPC-H.
Embodiment 3
The SOPC-H emulsion is improved the skin elasticity experiment
Contain 2%SOPC-H SOPC quality (: the hydrolysis hazelnut albumen quality=1:1) emulsion is improved skin elasticity
5 women testers (28-35 year)
Test article: adding content is the 1%SOPC-H emulsion
Test zone: the inboard of left forearm
Control zone: the inboard of right forearm
Test period: 4 week
Test article frequency of utilization: twice of every day
Test event: skin elasticity-CK-MC750 skin elasticity protos test suite PROTOS
Method of testing: the probe of use diameter 2mm is approximately the zone of 3mm with the vacuum suction diameter of 0.045MPa.Probe can continue at the skin 1.5N that exerts pressure, measure and do not use fixative.In order to keep measuring the concordance of skin, use the masterplate holder during measurement, the patient turns to head and measures the buccal offside, so that probe can keep vertical with buccal skin, slightly exerts oneself in order to avoid probe slides simultaneously.Attract skin then to loosen in 2 seconds 2 seconds.So circulation 5 times when measuring the fatigability of skin, total Measuring Time is 20 seconds.The result adopts time deformation curve and area to describe.At the elasticity number of measuring skin the 0th, 1,2 and 4 weeks, get 5 people's average elasticity numerical value as the result.Result of the test shows that containing 2% SOPC-H emulsion improves skin elasticity and good effect is arranged, data such as table 2:
Table 2
| Time | 0 week | 1 week | 2 weeks | 3 weeks | 4 weeks |
| Mean values | 17 | 17.8 | 18.3 | 18.7 | 18.9 |
Use separately to contain 1% SOPC emulsion and contain 1% hydrolysis hazelnut protein emulsion and improve skin elasticity and all produce effect data such as table 3:
Table 3
| Time | 0 week | 1 week | 2 weeks | 3 weeks | 4 weeks |
| The 1%SOPC mean values | 17 | 17.3 | 17.5 | 17.6 | 17.7 |
| 1% hydrolysis hazelnut albumen mean values | 17.1 | 17.3 | 17.5 | 17.6 | 17.7 |
Claims (5)
1. one kind is used for the compositions that the skin plain weave compacts, and it is characterized in that, the following quality of said composition consists of than the component of component: the hydrolysis hazelnut albumen of the super procyanidin of 30%-70% and 30%-70%, each component sum is 100%.
2. compositions of compacting for the skin plain weave according to claim 1 is characterized in that, the following quality of said composition consists of than the component of component: the hydrolysis hazelnut albumen of the super procyanidin of 40%-60% and 40%-60%, each component sum is 100%.
3. compositions of compacting for the skin plain weave according to claim 1 and 2 is characterized in that, described super procyanidin extracts from French VITIS VINIFERA Fructus Vitis viniferae, is a kind of oligomer procyanidin.
4. compositions of compacting for the skin plain weave according to claim 1 and 2 is characterized in that the structural formula of described super procyanidin is formula 1:
Formula 1.
5. compositions of compacting for the skin plain weave according to claim 1 and 2 is characterized in that described hydrolysis hazelnut protein CAS is numbered 100209-45-8.
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| CN201210459570.8A CN102895129B (en) | 2012-11-15 | 2012-11-15 | Composition for smoothing out wrinkles on skin and firming skin |
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| CN201210459570.8A CN102895129B (en) | 2012-11-15 | 2012-11-15 | Composition for smoothing out wrinkles on skin and firming skin |
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| CN102895129A true CN102895129A (en) | 2013-01-30 |
| CN102895129B CN102895129B (en) | 2014-02-19 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105852124A (en) * | 2016-04-11 | 2016-08-17 | 林映津 | Preparation method of anthocyanin-containing collagen |
| CN108294999A (en) * | 2018-04-13 | 2018-07-20 | 李海珍 | A kind of composition and preparation method thereof for skin care |
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| EP1541040A1 (en) * | 2003-12-04 | 2005-06-15 | Cognis Iberia S.L | Composition for oral administration (VI) comprising an extract or active agents of Medicago sativa |
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Patent Citations (2)
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| EP1541158A1 (en) * | 2003-12-04 | 2005-06-15 | Cognis Deutschland GmbH & Co. KG | Antioxydant composition for oral or topical administration |
| EP1541040A1 (en) * | 2003-12-04 | 2005-06-15 | Cognis Iberia S.L | Composition for oral administration (VI) comprising an extract or active agents of Medicago sativa |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105852124A (en) * | 2016-04-11 | 2016-08-17 | 林映津 | Preparation method of anthocyanin-containing collagen |
| CN108294999A (en) * | 2018-04-13 | 2018-07-20 | 李海珍 | A kind of composition and preparation method thereof for skin care |
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| CN102895129B (en) | 2014-02-19 |
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