CN102872476A - Compounded freshener, preparation method thereof and disposable sanitary product - Google Patents

Compounded freshener, preparation method thereof and disposable sanitary product Download PDF

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CN102872476A
CN102872476A CN2012102855397A CN201210285539A CN102872476A CN 102872476 A CN102872476 A CN 102872476A CN 2012102855397 A CN2012102855397 A CN 2012102855397A CN 201210285539 A CN201210285539 A CN 201210285539A CN 102872476 A CN102872476 A CN 102872476A
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freshener
compound
preparation
menthol
organic solvent
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CN102872476B (en
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蔡增雄
张富山
孙晓丽
罗梅芳
郭裕盛
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FUJIAN HENGAN HOUSEHOLD LIFE ARTICLE CO., LTD.
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QUANZHOU JINJIANG HENGAN HEALTH SCIENCE & TECHNOLOGY Co Ltd
Hengan Fujian Holding Group Co Ltd
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Abstract

The invention discloses a compounded freshener, a preparation method thereof and a disposable sanitary product, which solves the problems of short refreshing duration, unhealthy side effects and the like in the using of the existing freshener and products containing the freshener. The freshener at least comprises mentha camphor, menthyl lactate, menthane carboxamide (N-Ethyl-p-menthane-3-carboxamide, C13H25NO) and organic solvent dissolving the mentha camphor, the menthyl lactate and the menthane carboxamide. The preparation method of the freshener at least comprises the steps of preparing the organic solvent and dissolving the mentha camphor, the menthyl lactate and the menthane carboxamide in the organic solvent. The compounded freshener is sprayed on the disposable sanitary product. The compounded freshener, the disposable sanitary product and the preparation method of the compounded freshener have the advantages that the refreshing effect is good, the refreshing duration is long, the refreshing reaction speed is high, and adverse side effects do not exist.

Description

Compound freshener, compound freshener preparation method and disposable sanitary articles
Technical field
The present invention relates to the preparation method of a kind of compound freshener, compound freshener and the disposable sanitary articles of being made by described compound freshener.
Background technology
Present known disposable sanitary articles is such as sanitary towel, sanitary pad, diaper etc.These disposable sanitary articles are being typically provided with freshener with the human skin contact side, and common freshener is menthol.It is strong that menthol has explosive force, i.e. can obviously experience refrigerant effect in the short time and cooling effect strong.
But there is following defective in menthol: 1, menthol is owing to having stronger volatility, and the effect persistent period is short; 2, in order to supply a gap 1, usually employing method is for strengthening the amount of reagent; But can cause simultaneously a large amount of volatilization in the process of production at product, transportation, preservation, economic benefit is bad; This external use later stage is caused the user adverse side effects such as sense, numbness and stimulation of burning.
Summary of the invention
For overcoming the problems referred to above, the invention provides and a kind ofly can produce fast the disposable sanitary articles that refrigerant sense can keep lastingly the preparation method of the compound freshener of refrigerant sense, compound freshener and use described compound freshener simultaneously.
For reaching above-mentioned purpose, the compound freshener of the present invention comprises the organic solvent of menthol, menthyl lactate, amide of mint and dissolving above-mentioned substance at least.
Preferably, described compound freshener also comprises Vitamin E acetate.
Preferably, the mass ratio between described menthol, menthyl lactate, described amide of mint and the described Vitamin E acetate is 5-25: 2-22: 0.1-10: 0.01-0.5.
Preferably, described organic solvent is one or more in ethanol, propylene glycol, glycerol and the sorbic alcohol.
For reaching above-mentioned purpose, the preparation method of the compound freshener of the present invention may further comprise the steps:
Step 1: preparation organic solvent;
Step 2: menthol, menthyl lactate and amide of mint are dropped in the described organic solvent, and stir until fully dissolving;
Further, described compound freshener preparation method also comprises
Step 3: Vitamin E acetate is put in the solution of finishing above-mentioned steps 2, and be stirred to mix homogeneously.
Further, the mass ratio between described menthol, menthyl lactate, described amide of mint and the described Vitamin E acetate is 5-25: 2-22: 0.1-10: 0.01-0.5.
Further, described organic solvent is one or more in ethanol, propylene glycol, glycerol and the sorbic alcohol.
For reaching above-mentioned purpose, disposable sanitary articles of the present invention is coated with above-mentioned compound freshener at described disposable sanitary articles, and described disposable sanitary articles is sanitary towel, sanitary pad or diaper.
Particularly, the consumption of the described compound freshener that sprays of the described disposable sanitary articles of every a slice is the 0.01-0.15 gram.
The beneficial effect of the compound freshener of the present invention, its preparation method and disposable sanitary articles:
1, the compound freshener of the present invention, in numerous refrigerant medicines with refrigerant effect, select that explosive force is strong, cooling effect is good menthol, explosive force are weak, the menthyl lactate of longer duration and cooling effect slowly, the amide of mint of good stability, cooling effect, above three's combined effect, can remedy the deficiency of any refrigerant medicine independent role, reach that cooling effect is strong, longer duration, the fast effect of refrigerant rapidity.
2, the compound freshener of the present invention adopts menthol, user produced burn, menthyl lactate, the amide of mint three of the ill effects such as numbness and stimulation make up and replaced traditional single menthol, thereby improved the comfort of product.
3, the compound freshener of the present invention adopts little menthyl lactate and the amide of mint of volatilization, has a consumption little, and effect is good, good in economic efficiency characteristics.
4, the compound freshener of the present invention has added Vitamin E acetate; Because Vitamin E acetate has extremely strong antioxidation, for the preservation of compound freshener and the lasting performance of drug effect facilitation is arranged.
5, the compound freshener of the present invention, setting by the quality proportioning, so that cooling effect further can be that refrigerant effect free of discontinuities continues, the persistent period is longer and lasting effect is more stable, and do not have during heavy dose of the use menthol to use burning sensation, the numbness in later stage, the ill effect of stimulation.
6, the organic solvent of the compound freshener of the present invention adopts the mixture of a kind of, two kinds, three kinds or four kinds of ethanol, propylene glycol, glycerol and sorbic alcohol, has wide, the effect such as cost is low of drawing materials.
7, the compound freshener preparation method of the present invention has preparation simply, and quick, the raw material of employing is economical and practical, and the compound freshener of preparing has the described effect of above-mentioned 1-6.
8, disposable sanitary articles of the present invention adopts the compound freshener of the present invention, has the characteristics such as cooling effect is good, cooling effect lasting, experience cooling effect speed is fast.
9, disposable sanitary articles of the present invention adopts the compound freshener of the present invention, has solved the various defectives of traditional single freshener effect, and having simultaneously not can the calcination skin, the use location produces numb and stimulate bad sensation.
The specific embodiment
Below the present invention will be further described.
Embodiment one:
The compound freshener of the present embodiment comprises the organic solvent of menthol, menthyl lactate, amide of mint and dissolving above-mentioned substance at least.
Menthol claims again Mentholum, the water white transparency acicular crystal, and molecular formula is C10H20O, molecular weight 156.27.It produces cooling effect by the cold and hot receptive neuron on the chafe, and its refrigerant sense explosive force is strong but the persistent period is shorter.
Menthyl lactate is a kind of menthol derivative, white crystal, and molecular formula is C13H24O3, molecular weight 228.33..It can be take menthol and Pfansteihl as raw material, with cyclohexane extraction band water, esterification is refining forms.The mechanism of action of its cooling effect is the same with menthol, its cooling effect explosive force a little less than, refrigerant sense is about half of menthol, but longer duration, and does not have the ill effects such as the calcination of use later stage, numbness and stimulation of similar heavy dose of menthol.
Amide of mint is the derivant of menthol, white crystal, and molecular formula is C13H25NO, molecular weight 211.35..It can be as raw material take menthol, form through chlorination, carboxylic acid and amidatioon three one-step refinings, the mechanism of action of its cooling effect is the same with menthol, its cooling effect is slow, the stable enhancing, final cooling effect reaches 1.5 times of menthol, and the lasting long period, and there are not the ill effects such as use later stage burning sensation, numbness and stimulation of similar heavy dose of menthol.
Above-mentioned three kinds of materials all can produce refrigerant effect to human body, but three's material respectively has pluses and minuses, all have different defectives when using separately.The compound freshener of the present embodiment, then be in numerous freshener medicines, according to the pluses and minuses of each medicine and cooling effect is good, the longer duration purpose, pick out these three kinds can complementary pluses and minuses material be dissolved in again organic solvent, form the described compound freshener of the present embodiment.
The described compound freshener of the present embodiment, when described Mentholum remedies described menthyl lactate and described amide of mint independent role owing to strong first performance drug effect of explosive force during use, the slowly characteristics of performance drug effect, the fast characteristics of drug effect performance when having simultaneously the Mentholum independent role can make user very first time enteroception to cooling effect.
The described compound freshener of the present embodiment, when described Mentholum is brought into play the later stage of refrigerant effect or after described Mentholum loses drug effect, described menthyl lactate and described amide of mint begin to bring into play drug effect successively, thereby can reach the effect of the refrigerant drug effect of long-time performance.Because menthyl lactate and amide of mint all can not make human body produce the ill effects such as numbness, stimulation, on the basis that prolongs effective drug duration, can not produce adverse side effect.
Therefore, arbitrarily menthol, menthyl lactate and three kinds of material combineds effect of amide of mint of proportioning, menthol independent role with respect to homogenous quantities, can reduce or can not produce the numbness of using the later stage, stimulate and burn adverse side effect and effective drug duration longer, the independent role of relative menthyl lactate, have strong drug action, performance drug effect fast advantage has separately rapidly characteristics of drug effect with respect to amide of mint.
Comprehensively above-mentioned, the described compound freshener of the present embodiment have cooling effect rapidly, the cooling effect performance time is long, effect is strong and without bad side effect or the little characteristics of side effect.
Menthol, menthyl lactate and amide of mint all are Organic substances, and according to the similar compatibility principle, above-mentioned substance all can be dissolved in the organic solvent, thereby make the described compound freshener of the present embodiment.
Further, a kind of in described organic solvent preferred alcohol, propylene glycol, glycerol, the sorbic alcohol, or multiple mixed liquor.
In addition and since reduced menthol consumption, increased menthyl lactate and amide of mint, thereby avoided in order to reach the human body that certain effect uses heavy dose of menthol to bring the untoward reaction such as burning sensation, numbness and stimulation being arranged.With respect to using heavy dose of menthol to prolong the time of refrigerant sense, have storage, transportation, certainly easy in addition, can not produce a large amount of volatilizations and bring disadvantageous economic benefit.Following table is the comparison of effect between the different formulations freshener.Letter A represents menthol, letter b and represents that menthyl lactate, letter C represent amide of mint, alphabetical D represents Vitamin E acetate.
Figure BDA00001998091400061
Figure BDA00001998091400071
Refrigerant response speed, cooling effect, refrigerant persistent period and side effect etc. all are the fresheners according to above-mentioned quality proportioning in the upper table, get the material of homogenous quantities by comparing gained.When having formed compound freshener of the present invention by menthol, menthyl lactate and three kinds of materials of amide of mint as can be known by above-mentioned table, the amide of mint of refrigerant response speed presentate one and menthyl lactate are all fast, and compound freshener wall menthyl lactate cooling effect is strong; The adverse side effects such as the numbness of more single menthol, stimulation, calcination are weak or have no side effect.
Embodiment two:
The compound freshener of the present embodiment has also comprised Vitamin E acetate on the basis of embodiment one.
Vitamin E acetate claims again the tocopherol alkyl caproate, faint yellow oiliness thick liquid, and molecular formula C31H52O3 has stronger antioxidant effect.Basis at the compound freshener of embodiment one has increased the strong Vitamin E acetate of non-oxidizability, so that the memory time of product is longer, result of use is kept more lasting.
Embodiment three:
The compound freshener of the present embodiment comprises menthol, menthyl lactate, amide of mint and Vitamin E acetate, and the mass ratio between the above-mentioned substance is that mass ratio is 5-25: 2-22: 0.1-10: 0.01-0.5.
On the basis of embodiment one, the present embodiment adopts preferential proportioning, the free of discontinuities that can guarantee refrigerant drug effect continues performance, guarantee that simultaneously drug effect continues a very stable level, and can not cause refrigerant drug effect off and on, at times strong and at other times weak, can reach the relay of three kinds of drug effect performances between the refrigerant material, so that drug effect is lasting, stable, lasting.
Embodiment four:
The preparation method of the compound freshener of the present embodiment comprises two steps:
The first step: preparation or preparation organic solvent; Described organic solvent can be one or both mixed liquor or three kinds mixed liquor or four kinds the mixed liquor in ethanol, propylene glycol, glycerol and the sorbic alcohol;
Second step: menthol, menthyl lactate and amide of mint are added respectively in the organic solvent of the described preparation of the first step or preparation, and stir.
The preparation method letter of the compound freshener of the present embodiment is answered, and it is good that the compound freshener of preparing has a cooling effect, refrigerant longer duration, the advantage that has no side effect.
Embodiment five:
The preparation method of the compound freshener of the present embodiment has dropped into the additive Vitamin E acetate on the basis of above-described embodiment four; The effect of additive useful with preparation after the maintenance of compound freshener and the lasting performance of drug effect.
And further, the mass ratio between described menthol, menthyl lactate, amide of mint and the Vitamin E acetate is 5-25: 2-22: 0.1-10: 0.01-0.5.
As: take by weighing respectively 20 kilograms of ethanol, 35 kilograms of propylene glycol, 17.8 kilograms of glycerol, mixing and stirring forms the organic solvent of the described compound freshener of the present embodiment.Get 3 kilograms of 14 kilograms of menthols, 10 kilograms of menthyl lactates, amide of mint and drop into respectively in the organic solvent that above-mentioned steps made, continue again to stir until fixed substance dissolving and the mix homogeneously that drops into.Next the Vitamin E acetate that adds 0.2 kilogram, again stirring to obtain the interior compound freshener of above-mentioned recipe ratio.According to the compound freshener of said ratio preparation, the refrigerant persistent period of 0.05 gram is two hours.
Embodiment six:
Measure at first respectively 16.8 kilograms of ethanol, 25 kilograms of propylene glycol, 15 kilograms of glycerol, mix homogeneously forms mixed solution, and this mixed solution is the described organic solvent of the described compound freshener of the present embodiment.Secondly, getting 5 kilograms of 20 kilograms of menthols, 18 kilograms of menthyl lactates, amide of mint drops into respectively in the above-mentioned organic solvent.The Vitamin E acetate that again adds 0.3 kilogram, the i.e. described compound freshener of the present embodiment of system stirs.The refrigerant persistent period that the compound freshener 0.1 for preparing according to said ratio restrains is two hours.The present embodiment adopts optimum ratio can realize free of discontinuities, the longer duration of cooling effect in the compound freshener mechanism, and efficacy stability.
Embodiment seven:
The compound freshener that the surface spraying compound freshener of the present invention of the present embodiment disposable sanitary articles contact human skin side or preparation method of the present invention are produced.
Described disposable sanitary articles comprises sanitary towel, sanitary pad, diaper etc.Sanitary towel, sanitary pad, diaper have liquid permeability surface layer, opaque liquid bottom and the absorbent core layer between surface layer and bottom, and the Excreta of energy absorbing bodily provides comfortable health care for user.Wherein said liquid permeability surface layer is the surface of contact human skin side.
In the preparation engineering of above-mentioned disposable sanitary articles, the described compound freshener of arbitrary embodiment among the embodiment one to embodiment three or embodiment five prepared compound fresheners are sprayed to surface layer or the absorbent core layer of described disposable sanitary articles with spraying equipment.When using the compound freshener of surface layer directly and skin contact, the compound freshener of sandwich layer passes described liquid permeability surface layer and skin contact by volatilization, can realize that cooling effect is swift in response, cooling effect is good, the characteristics of longer duration.
Embodiment eight:
A kind of sanitary pad of the present embodiment comprises liquid top layer, absorbent core layer and liquid-tight bottom at least; On described liquid top layer or described absorbent core layer be coated with 0.05 gram by menthol, menthyl lactate, amide of mint and Vitamin E acetate according to 5-25: 2-22: 0.1-10: the compound freshener of 0.01-0.5 recipe ratio configuration.The untoward reaction such as the sense of burning, numbness and stimulation that the time that refrigerant drug effect continues is long, the use later stage does not use heavy dose of menthol to cause.
Embodiment nine:
A kind of sanitary towel of the present embodiment evenly is coated with the of the present invention compound freshener of 0.1 gram in the contact human skin side of sanitary towel.Described sanitary towel cooling effect is good, longer duration, effect stability.
Above; be preferred embodiment of the present invention only, but protection scope of the present invention is not limited to this, anyly is familiar with those skilled in the art in the technical scope that the present invention discloses; the variation that can expect easily or replacement all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain that claim was defined.

Claims (10)

1. a compound freshener is characterized in that, described compound freshener comprises the organic solvent of menthol, menthyl lactate, amide of mint and dissolving above-mentioned substance at least.
2. compound freshener according to claim 1 is characterized in that, described compound freshener also comprises Vitamin E acetate.
3. compound freshener according to claim 2 is characterized in that, the mass ratio between described menthol, menthyl lactate, described amide of mint and the described Vitamin E acetate is 5-25: 2-22: 0.1-10: 0.01-0.5.
4. each described compound freshener is characterized in that according to claim 1-3, and described organic solvent is one or more in ethanol, propylene glycol, glycerol and the sorbic alcohol.
5. the preparation method of a compound freshener is characterized in that, described compound freshener preparation method may further comprise the steps:
Step 1: preparation organic solvent;
Step 2: menthol, menthyl lactate and amide of mint are dropped in the described organic solvent, and stir until fully dissolving.
6. compound freshener preparation method according to claim 5 is characterized in that, described compound freshener preparation method also comprises
Step 3: Vitamin E acetate is put in the solution of finishing above-mentioned steps 2, and be stirred to mix homogeneously.
7. compound freshener preparation method according to claim 6 is characterized in that, the mass ratio between described menthol, menthyl lactate, described amide of mint and the described Vitamin E acetate is 5-25: 2-22: 0.1-10: 0.01-0.5.
8. each described compound freshener preparation method is characterized in that according to claim 5-7, and described organic solvent is one or more in ethanol, propylene glycol, glycerol and the sorbic alcohol.
9. a disposable sanitary articles is characterized in that, is coated with the compound freshener described in the claim 1 at described disposable sanitary articles, and described disposable sanitary articles is sanitary towel, sanitary pad or diaper.
10. disposable sanitary articles according to claim 9 is characterized in that, the consumption of the described compound freshener that the described disposable sanitary articles of every a slice sprays is the 0.01-0.15 gram.
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CN104274342A (en) * 2013-07-03 2015-01-14 吴文兵 Fatigue driving prevention and control essence extracted from plants
CN104988742A (en) * 2015-06-11 2015-10-21 江苏阳光股份有限公司 Cold-feeling easy-care treating method of cotton shirt
CN109394625A (en) * 2018-12-11 2019-03-01 广东好顺欧迪斯科技股份有限公司 Coolant compositions and its manufacture craft

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104274342A (en) * 2013-07-03 2015-01-14 吴文兵 Fatigue driving prevention and control essence extracted from plants
CN104988742A (en) * 2015-06-11 2015-10-21 江苏阳光股份有限公司 Cold-feeling easy-care treating method of cotton shirt
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CN109394625A (en) * 2018-12-11 2019-03-01 广东好顺欧迪斯科技股份有限公司 Coolant compositions and its manufacture craft

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