CN102831814B - A kind of gram-negative bacteria cell membrane endotoxin model teaching aid - Google Patents

A kind of gram-negative bacteria cell membrane endotoxin model teaching aid Download PDF

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Publication number
CN102831814B
CN102831814B CN201210327149.1A CN201210327149A CN102831814B CN 102831814 B CN102831814 B CN 102831814B CN 201210327149 A CN201210327149 A CN 201210327149A CN 102831814 B CN102831814 B CN 102831814B
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outer shroud
middle ring
ring
inner ring
gram
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CN201210327149.1A
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CN102831814A (en
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朱越雄
曹广力
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Suzhou University
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Suzhou University
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Abstract

The invention discloses a kind of gram-negative bacteria cell membrane endotoxin model teaching aid, it is characterized in that: it comprises inner ring, middle ring, outer shroud and inserted link, described inner ring, middle ring, outer shroud are all half annulus, the described middle ring of described outer shroud parcel, described middle ring wraps up described inner ring, the interior diameter of described outer shroud is identical with the overall diameter of described middle ring, and the interior diameter of described middle ring is identical with the overall diameter of described inner ring, and described inserted link is arranged on the outer wall of described outer shroud.The present invention can make observer be well understood to the endotoxic outward appearance of gram-negative bacteria cell membrane, structure and principle of work, can also save transport space, reduces transportation cost.

Description

A kind of gram-negative bacteria cell membrane endotoxin model teaching aid
Technical field
The present invention relates to a kind of model teaching aid, particularly relate to a kind of gram-negative bacteria cell membrane endotoxin model teaching aid.
Background technology
Endotoxin is a kind of composition in gram-negative bacterial cell wall, is called lipopolysaccharides.Lipopolysaccharides is virose to host.Endotoxin only has when bacterial death dissolving or just discharges after destroying bacterial cell by artificial means.
Human body is very responsive to bacterial endotoxin.Appropriateness heating, Marjoram Extract, inflammatory reaction etc. can be caused for the useful immune protection response of host; because the overwhelming majority can be increased by total white blood cells in the blood stream of patients of gram positive bacterial infection; so present doctor is before diagnosis; in order to tentatively difference is bacterial infection or viral infection; usually to chemically examine the blood of patient; carry out sum to leucocyte to measure and differential count; and by the patient of virus infections, its total white blood cells and neutrophil leucocyte number percent are substantially in range of normal value.When gram negative pathogenic bacterium mass mortality in focus or blood flow, when a large amount of endotoxins discharged enter blood, endotoxemia can be there is.A large amount of endotoxin produces Cucumber and acts on thin vessels and cause dysfunction and cause microcirculation disorder after entering blood, clinical manifestation is microcirculation failure, low blood pressure, anoxic, acidosis etc., so cause patient to suffer a shock, this pathological reaction is called endotoxin shock.
To sum up tell, particularly important for endotoxic research, by the control of induced by endotoxin with utilize and can contribute in health care.But generally impart knowledge to students with schematic diagram at teaching field now, due to endotoxin be positioned at cell membrane outermost layer, be covered on the glutinous peptide of cell membrane, the picture of plane can not analyze its structure well, explains its principle of work, so need a three-dimensional model to carry out auxiliary explanation.
Summary of the invention
Object of the present invention provide a kind of structure simple, be easy to carry and the gram-negative bacteria cell membrane endotoxin model teaching aid of endotoxin structure and principle of work can be shown well.
For achieving the above object, the technical solution used in the present invention is: a kind of gram-negative bacteria cell membrane endotoxin model teaching aid, comprise inner ring, middle ring, outer shroud and at least one inserted link, described inner ring, middle ring, outer shroud are all half annulus, the described middle ring of described outer shroud parcel, described middle ring wraps up described inner ring, the interior diameter of described outer shroud is identical with the overall diameter of described middle ring, the interior diameter of described middle ring is identical with the overall diameter of described inner ring, described inserted link is arranged on the outer wall of described outer shroud, and described inserted link is perpendicular to the outer wall of described outer shroud.
Preferably, inserted link described in each comprises head, middle part, afterbody, and to be that multiple annulus is stacking form at described middle part, and described afterbody is that three right cylinders are in series, and described head, middle part, afterbody are fixedly connected sequentially.
Preferably, described outer shroud outer wall is provided with jack, the apical head of described inserted link is provided with the buckle coordinated with described jack.Described jack uniform combination is arranged on described outer shroud outer wall.
Preferably, the inwall of described outer shroud is connected by buckle with the outer wall of described middle ring, and the inwall of described middle ring is connected by buckle with the outer wall of described inner ring.
In technique scheme, the material of all parts is all plastics, and described inner ring, middle ring, outer shroud all have certain thickness, and described outer shroud, middle ring, inner ring not only can use buckle to connect, and magnetic material also can be used to connect.
Due to the utilization of technique scheme, the present invention compared with prior art has following advantages:
1, because structure of the present invention is 3-D solid structure, observer can be made to be well understood to the endotoxic outward appearance of gram-negative bacteria cell membrane and structure, to be more suitable for teaching explanation.
2, due to the present invention's employing is disassembly and assembly structure, can not only save transport space, reduces transportation cost, can also increase the manipulative ability of user, enhance memory, more understand the endotoxic structure of gram-negative bacteria cell membrane and principle of work in depth.
Accompanying drawing explanation
Fig. 1 is the stereographic map of the embodiment of the present invention;
Fig. 2 is exploded view;
Fig. 3 is front view;
Fig. 4 is inserted link figure;
Fig. 5 is the A-A sectional view of Fig. 3.
Wherein: 1, outer shroud; 2, middle ring; 3, inner ring; 4, inserted link; 5, head; 6, middle part; 7, afterbody; 8, jack; 9, buckle.
Embodiment
Below in conjunction with embodiment shown in the drawings, the invention will be further described:
Embodiment one: shown in accompanying drawing 1-5.
A kind of gram-negative bacteria cell membrane endotoxin model teaching aid, it comprises inner ring 3, middle ring 2, outer shroud 1 and inserted link 4, inner ring 3, middle ring 2, outer shroud 1 are all half annulus, ring 2 during outer shroud 1 wraps up, middle ring 2 wraps up inner ring 3, and the interior diameter of outer shroud 1 is identical with the overall diameter of middle ring 2, and the interior diameter of middle ring 2 is identical with the overall diameter of inner ring 3, inserted link 4 is arranged on the outer wall of outer shroud, and inserted link 4 is perpendicular to the outer wall of described outer shroud 1.
Inserted link comprises head 5, middle part 6, afterbody 7, and to be that multiple annulus is stacking form at middle part, and afterbody is that three right cylinders are in series, and head 5, middle part 6, afterbody 7 are fixedly connected sequentially.The outside surface of outer shroud 1 is provided with the jack 8 of uniform combination arrangement, head 5 top of inserted link is provided with the buckle 9 coordinated with jack 8.The inwall of outer shroud 1 is connected by buckle with the outer wall of middle ring 2, and the inwall of middle ring 2 is connected by buckle with the outer wall of inner ring 3.
During combination gram-negative bacteria cell membrane endotoxin model teaching aid, inner ring 3 is stuck in middle ring 2, middle ring 2 is stuck in outer shroud 1, finally plug inserted link 4.As required, 1 or many inserted links can be set, usually, for the object of demonstration, one row inserted link can be set, such as, in Fig. 3, illustrate and 3 group of 15 row jack is set on outer shroud outer wall, often row are provided with 5 jacks, are provided with 5 inserted links, are inserted in 5 jacks of same row, so that demonstration.
In gram-negative bacteria cell membrane endotoxin complete structure model teaching aid, show the endotoxic basic structure of gram-negative bacteria cell membrane and action principle, outer field protein/fat (outer shroud 1 namely in model teaching aid) is wrapped in peptide glycan (the middle ring 2 namely in model teaching aid), peptide glycan is wrapped in cell membrane (inner ring 3 namely in model teaching aid), when discharging endotoxin (inserted link 4 namely in model teaching aid) after cell death cracking.Endotoxin is the lipopolysaccharides in gram-negative bacterial cell wall, and its molecular structure is made up of O specific polysaccharide (afterbody 7 namely in model teaching aid), non-specific core polysaccharide (middle part 6 namely in model teaching aid) and lipid A (head 5 namely in model teaching aid) three parts.
The model teaching aid of 3-D solid structure can make observer be well understood to the endotoxic outward appearance of gram-negative bacteria cell membrane and structure, be more suitable for teaching explanation, and disassembly and assembly structure is more conducive to user's intensification to the cognition of gram-negative bacteria cell membrane endotoxin structure and memory, and be conducive to packed and transported, save space and the cost of packed and transported.

Claims (1)

1. a gram-negative bacteria cell membrane endotoxin model teaching aid, it is characterized in that: comprise inner ring, middle ring, outer shroud and at least one inserted link, described inner ring, middle ring, outer shroud are all half annulus, the described middle ring of described outer shroud parcel, described middle ring wraps up described inner ring, and the interior diameter of described outer shroud is identical with the overall diameter of described middle ring, and the interior diameter of described middle ring is identical with the overall diameter of described inner ring, described inserted link is arranged on the outer wall of described outer shroud, and described inserted link is perpendicular to the outer wall of described outer shroud; Inserted link described in each comprises head, middle part, afterbody, and to be that multiple annulus is stacking form at described middle part, and described afterbody is that three right cylinders are in series, and described head, middle part, afterbody are fixedly connected sequentially; Described outer shroud outer wall is provided with jack, and the apical head of described inserted link is provided with the buckle coordinated with described jack; The inwall of described outer shroud is connected by buckle with the outer wall of described middle ring, and the inwall of described middle ring is connected by buckle with the outer wall of described inner ring.
CN201210327149.1A 2012-09-06 2012-09-06 A kind of gram-negative bacteria cell membrane endotoxin model teaching aid Expired - Fee Related CN102831814B (en)

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CN103198744A (en) * 2013-04-28 2013-07-10 苏州大学 Gram positive bacteria cell wall model teaching aid
CN104143283A (en) * 2014-07-31 2014-11-12 江南大学 Gram-negative bacterium peptidoglycan structural model teaching tool

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CN2768115Y (en) * 2005-02-01 2006-03-29 李娜 Teaching tool for biology teaching
CN201307362Y (en) * 2008-10-07 2009-09-09 刘岩 Animal and plant cell model made of fruits and vegetables
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