Summary of the invention
The objective of the invention is to overcome the deficiency of prior art, provide a kind of and suit the medicine to the illness that property is strong, cure rate is high, draw materials easily a kind of concentrated pill of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal of taking convenience.
In order to reach above purpose; The technical scheme that the present invention taked is: this a kind of concentrated pill of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal is characterized in that: it is to be processed by the raw material of Chinese medicine of following mass percent: Radix Astragali 16.87-20.63%, Rhizoma Atractylodis Macrocephalae 8.44-10.32%, Pericarpium Citri Reticulatae 8.44-10.32%, Rhizoma Cimicifugae 5.62-6.88%, Radix Bupleuri 11.25-13.75%, Radix Angelicae Sinensis 8.43-10.31%, Radix Codonopsis 11.25-13.75%,, Semen Pruni 5.62-6.88%, Fructus Cannabis 13.5-16.5%.Wherein each raw material of Chinese medicine constituent content percent sum equals 100%.Optimizing the raw material of Chinese medicine prescription is: the Radix Astragali 18.75%, the Rhizoma Atractylodis Macrocephalae 9.38%, Pericarpium Citri Reticulatae 9.38%, Rhizoma Cimicifugae 6.25%, Radix Bupleuri 12.50%, Radix Angelicae Sinensis 9.37%, Radix Codonopsis 12.5%, Semen Pruni 6.25%, Fructus Cannabis 15.62%.This a kind of concentrated pill of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal is made by following steps: one, the ratio in Radix Astragali 16.87-20.63%, Rhizoma Atractylodis Macrocephalae 8.44-10.32%, Pericarpium Citri Reticulatae 8.44-10.32%, Rhizoma Cimicifugae 5.62-6.88%, Radix Bupleuri 11.25-13.75%, Radix Angelicae Sinensis 8.43-10.31%, Radix Codonopsis 11.25-13.75%, Semen Pruni 5.62-6.88%, Fructus Cannabis 13.5-16.5% accurately takes by weighing each raw material of Chinese medicine that cooks; When taking by weighing each raw material of Chinese medicine; The raw material of Chinese medicine Rhizoma Atractylodis Macrocephalae, Radix Codonopsis are mixed and put together; Semen Pruni, Fructus Cannabis are mixed and put together; Radix Bupleuri, Radix Angelicae Sinensis are mixed and put together, the Radix Astragali, Pericarpium Citri Reticulatae, Rhizoma Cimicifugae are mixed and put together; Two, will weigh up to mix the raw material of Chinese medicine Rhizoma Atractylodis Macrocephalae, the Radix Codonopsis put together and weigh up and mix Semen Pruni, the Fructus Cannabis of putting together and put into different drip pans respectively; Place in the baking oven dryly under 50 ℃ temperature, reach 5% when following to moisture, stop to heat; Naturally cooling must be done raw material of Chinese medicine; Three, the dried raw material of Chinese medicine that will reduce to room temperature takes out from baking oven; To mix the thick medicated powder that the raw material of Chinese medicine Rhizoma Atractylodis Macrocephalae, the Radix Codonopsis powder of putting together were broken into 20 mesh sieves earlier; Then thick medicated powder is incorporated in the raw material of Chinese medicine Semen Pruni and Fructus Cannabis that mixes, the thin medicated powder of mixing that was ground into 100 mesh sieves is subsequent use; Four, will weigh up and mix raw material of Chinese medicine Radix Bupleuri, the Radix Angelicae Sinensis put together and put into and carry device, and add domestic water, stir, soak to carrying device; Amount of water is raw material of Chinese medicine Radix Bupleuri, Radix Angelicae Sinensis quality sum 6 times, soaks after 30 minutes heating lixiviate 120 minutes; When carrying 90 minutes, add medicine boiler with mixing the raw material of Chinese medicine Radix Astragali, Pericarpium Citri Reticulatae, the Rhizoma Cimicifugae of putting together, and add domestic water to medicine boiler; Stir, soak, amount of water is the Radix Astragali, Pericarpium Citri Reticulatae, Rhizoma Cimicifugae quality sum 6 times; Carry end, stop heating, it is subsequent use to take off volatile oil; Five, the medicament mixed liquid that will carry in the device is incorporated medicine boiler into, and intense fire is heated to boiling, and slow fire boiling is 60 minutes again, stops heating, filters, and stays slag, gets a medicinal liquid; Six, add domestic water to the medicine boiler that fills medicinal residues, amount of water is Radix Bupleuri, Radix Angelicae Sinensis, the Radix Astragali, Pericarpium Citri Reticulatae, Rhizoma Cimicifugae quality sum 5 times, and intense fire is heated to boiling, and slow fire boiling is 60 minutes again; Stop heating, filter, stay slag, get the secondary medicinal liquid; Seven, squeezing medicinal residues, waste must squeeze medicinal liquid; To squeeze medicinal liquid and a medicinal liquid, the secondary medicinal liquid mixes, and gets admixing medical solutions; Eight, pour admixing medical solutions into medicine boiler, it is 1.08-1.1 that heating is concentrated into relative density, stops heating, reduces to room temperature; The ethanol that adds equal-volume 95%, fully mix homogeneously left standstill 12 hours; Filter, behind the filtrate recycling ethanol, continue to be concentrated into relative density again and be 1.30~1.35 thick paste; Nine, pour volatile oil into thick paste, will mix thin medicated powder and pour in the thick paste, in thick paste, add refined honey again, it is 17% of thick paste quality that refined honey is disliked addition; With the ball piece, pill bar, gradation, round; Process concentrated pill, it is dry that the concentrated pill of processing is placed on the shady and cool ventilation place, does to moisture to be lower than at 10% o'clock, and concentrated pill is wrapped with paraffin paper; The dress box, every box 10 balls, every ball 9 grams are a kind of concentrated pill patent medicine of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal.
Described a kind of concentrated pill of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal; It is characterized in that: institute adds refined honey and is made by following method: Mel is heated to 116-118 ℃; When the light yellow glossiness all even and fine steam bubble that seethes occurring, when twisting with the fingers toughness, stop heating with hands.Be the used refined honey of pill.
This a kind of pharmacology of treating the concentrated pill of sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal: fill blood, the strengthening the spleen stomach loosening bowel to relieve constipation.
Wherein: Radix Astragali sweet in the mouth, slightly warm in nature; Return lung, spleen, liver, kidney channel.Has the effect that benefiting QI for strengthening the superficies, arresting sweating take off, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema admittedly.It is weak to be used to treat the deficiency of vital energy, sinking of QI of middle-JIAO, and the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.
Rhizoma Atractylodis Macrocephalae bitter in the mouth, sweet, warm in nature; Return spleen, stomach warp.Have invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Be used for that insufficiency of the spleen lack of appetite, abdominal distention are had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Pericarpium Citri Reticulatae acrid in the mouth, hardship, warm in nature; Go into spleen, stomach, lung meridian.Have regulating qi-flowing for strengthening spleen, in the accent, dampness, clears phlegm.Cure mainly distension and fullness in the abdomen or pain, the dyspepsia of stagnation of QI in spleen and stomach.Abdominal distention uncomfortable in chest, indigestion and loss of appetite loose stool in the turbid damp resistance.Phlegm-damp is stopped up the cough and asthma of lung.
Rhizoma Cimicifugae acrid in the mouth, little sweet, cold nature; Return lung, spleen, stomach, large intestine channel.Has the rash of delivering, heat-clearing and toxic substances removing, the effect of elevate a turnable ladder yang-energy.Be used to treat headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome is sent out speckle; Proctoptosis, uterine prolapse.
Radix Bupleuri bitter in the mouth, suffering, cold nature; Return liver, gallbladder meridian.Have expelling pathogenic factors from the exterior and expel the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, the effect of elevate a turnable ladder yang-energy.Cure mainly cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, the uterus comes off, menoxenia.
Radix Angelicae Sinensis sweet in the mouth, suffering, warm in nature; Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Be used to treat blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Radix Codonopsis sweet in the mouth, little acid, property is flat; Return spleen, lung meridian.Has invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.These article can QI invigorating, can enrich blood again, and commonly used the treatment can not hemopoietic in the deficiency of vital energy, or blood deficiency is difficult activating QI, and the meeting color is pale or sallow, weak, dizziness.
Semen Pruni acrid in the mouth, hardship, sweet, property is flat; Return spleen, large intestine, small intestine meridian.Have and moisturize, laxation, the effect of relieving constipation.Be used to treat intestine-dryness due to consumption of fluid, stagnation of QI due to dyspepsia, abdominal distention constipation, edema, beriberi, dysuria.
The Fructus Cannabis sweet in the mouth, property is flat; Return spleen, stomach, large intestine channel.Effect merit with loosening bowel to relieve constipation, nourishing.Can strengthen and grow spleen the moon, the dry effect of intestine moistening, be used for the dryness of the intestine constipation of old man, puerpera and weak Tianjin insufficiency of blood more.
This a kind of instructions of taking of treating the concentrated pill of sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal is:
After meal half an hour warm water delivery service, three times on the one, one time 2 ball, 7 days is a course of treatment.
The medication taboo: period in a medicine, avoid the pungent and delicious food savoury of clothes.
Beneficial effect of the present invention is: a kind of concentrated pill of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal is provided, and this suiting the medicine to the illness property of concentrated pill is strong, and produce effects is fast, and treatment time is short; Therapeutic effect is good, and prescription is simple, draws materials easily; Taking convenience, cure rate 69.28%, effective percentage 100%.
Analysis of clinical
One, diagnosis basis
Diagnostic criteria according to " People's Republic of China's Chinese medicine industry standard-traditional Chinese medical science disease diagnosis criterion of therapeutical effect (ZY-T001.1-94) " TCM Gynecology difficulty in defecation after delivery sinking of QI due to deficiency of the spleen disease is formulated.
1, be hard and dry puerperal, a few days is not understood, or when separating under the involved and abstruse difficulty, but abdomen does not have distending pain, and diet is as usual.Shallow complexion, skin does not moisten.Or though meaning is arranged just puerperal, facing the lavatory, to exert duty weak, the sweating of breathing hard, lassitude just goes out not stiffly, or has a dizzy spell.
2, light red tongue, thin fur, the puckery or large and weak pulse of deficient pulse.
3, previously there is not the constipation history.
Two, efficacy evaluation
Criterion of therapeutical effect according to " People's Republic of China's Chinese medicine industry standard-traditional Chinese medical science disease diagnosis criterion of therapeutical effect (ZY-T001.1-94) " TCM Gynecology difficulty in defecation after delivery is formulated.
1 cures: stool is normal, does not have recurrence after the drug withdrawal.
2 take a turn for the better: stool is led to and owes smooth, or stool is normal, but recurs after the drug withdrawal.
3 do not heal: symptom does not have improvement.
Three, efficacy result analysis
From in January, 2010 to 2011 year December, make a definite diagnosis sinking of QI due to deficiency of the spleen type difficulty in defecation patient 153 examples altogether, wherein natural labor 98 examples; Cut open the palace and produce 55 examples; Minimum 21 years old of age, maximum 38 years old, with this a kind of 1-2 course of treatment of concentrated pill treatment of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal; Cure 106 examples, cure rate 69.28%; 47 examples that take a turn for the better, improvement rate 30.72%; Effective percentage 100%.
Specific embodiment
Embodiment 1
Accurately take by weighing each raw material of Chinese medicine that cooks in the ratio of the Radix Astragali 18.75%, the Rhizoma Atractylodis Macrocephalae 9.38%, Pericarpium Citri Reticulatae 9.38%, Rhizoma Cimicifugae 6.25%, Radix Bupleuri 12.50%, Radix Angelicae Sinensis 9.37%, Radix Codonopsis 12.5%, Semen Pruni 6.25%, Fructus Cannabis 15.62% and amount to 50kg.Wherein, Radix Astragali 9.375kg, Rhizoma Atractylodis Macrocephalae 4.69kg, Pericarpium Citri Reticulatae 4.69kg, Rhizoma Cimicifugae 3.125kg, Radix Bupleuri 6.25kg, Radix Angelicae Sinensis 4.685kg, Radix Codonopsis 6.25kg, Semen Pruni 3.125kg, Fructus Cannabis 7.81kg.When taking by weighing each raw material of Chinese medicine, the raw material of Chinese medicine Rhizoma Atractylodis Macrocephalae, Radix Codonopsis are mixed and put together, Semen Pruni, Fructus Cannabis are mixed and put together, Radix Bupleuri, Radix Angelicae Sinensis are mixed and put together, the Radix Astragali, Pericarpium Citri Reticulatae, Rhizoma Cimicifugae are mixed and put together; Put into different drip pans respectively with weighing up to mix the raw material of Chinese medicine Rhizoma Atractylodis Macrocephalae, the Radix Codonopsis of putting together and weigh up mixed Semen Pruni, Fructus Cannabis of putting together; Place in the baking oven dryly under 50 ℃ temperature, reach 5% when following to moisture, stop to heat; Naturally cooling must be done raw material of Chinese medicine; The dried raw material of Chinese medicine of reducing to room temperature is taken out from baking oven; To mix the thick medicated powder that the raw material of Chinese medicine Rhizoma Atractylodis Macrocephalae, the Radix Codonopsis powder of putting together were broken into 20 mesh sieves earlier; Then thick medicated powder is sneaked in the raw material of Chinese medicine Semen Pruni and Fructus Cannabis that mixes, the thin medicated powder 19kg of mixing that was ground into 100 mesh sieves is subsequent use; Mix raw material of Chinese medicine Radix Bupleuri, the Radix Angelicae Sinensis put together and put into and carry device weighing up, and add domestic water, stir, soak to carrying device; Amount of water is raw material of Chinese medicine Radix Bupleuri, Radix Angelicae Sinensis quality sum 6 times, soaks after 30 minutes heating lixiviate 120 minutes; When carrying 90 minutes, add medicine boiler with mixing the raw material of Chinese medicine Radix Astragali, Pericarpium Citri Reticulatae, the Rhizoma Cimicifugae of putting together, and add domestic water to medicine boiler; Stir, soak, amount of water is the Radix Astragali, Pericarpium Citri Reticulatae, Rhizoma Cimicifugae quality sum 6 times; Carry end, stop heating, it is subsequent use to take off volatile oil; Incorporate the medicament mixed liquid of carrying in the device into medicine boiler, intense fire is heated to boiling, and slow fire boiling is 60 minutes again, stops heating, filters, and stays slag, gets a medicinal liquid; Medicine boiler to filling medicinal residues adds domestic water, and amount of water is Radix Bupleuri, Radix Angelicae Sinensis, the Radix Astragali, Pericarpium Citri Reticulatae, Rhizoma Cimicifugae quality sum 5 times, and intense fire is heated to boiling, and slow fire boiling is 60 minutes again; Stop heating, filter, stay slag, get the secondary medicinal liquid; The squeezing medicinal residues, waste must squeeze medicinal liquid; To squeeze medicinal liquid and a medicinal liquid, the secondary medicinal liquid mixes, and gets admixing medical solutions; Pour admixing medical solutions into medicine boiler, it is 1.08-1.1 that heating is concentrated into relative density, stops heating, reduces to room temperature; The ethanol that adds equal-volume 95%, fully mix homogeneously left standstill 12 hours; Filter, behind the filtrate recycling ethanol, continue to be concentrated into relative density again and be 1.32 thick paste 42.5kg; Nine, volatile oil is poured in the thick paste, the thin medicated powder of subsequent use mixing is poured in the thick paste, in thick paste, add refined honey 7.3kg and ball piece again; The pill bar, gradation, round is processed 3320 of concentrated pills; It is dry that the concentrated pill of processing is placed on the shady and cool ventilation place, does to moisture to be lower than at 10% o'clock, concentrated pill wrapped the dress box with paraffin paper; Every box 10 balls, every ball 9 grams, every ball 9 grams of patent medicine are a kind of concentrated pill patent medicine of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal.
With these a kind of concentrated pill treatment treatment difficulty in defecation after delivery patient 51 examples of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal, cure 39 examples, cure rate 76.5%, 12 examples that take a turn for the better, improvement rate 23.5%, effective percentage 100%.
Model case
The Wang, woman, 25 years old, the Laiwu City high and new technology industrial development zone nurse of commune hospital.On February 6th, 2010, produce a girl baby in my institute, natural labor, the first-born, row perineum side cutting art, section go to a doctor main suit at me 3 days puerperal: effort when defecating, under the involved and abstruse difficulty, just go out not stiff, the sweating of breathing hard, the companion has a dizzy spell, in the past from no constipation.Examine and see: shallow complexion, skin does not moisten.Light red tongue, thin fur, deficient pulse.Be diagnosed as sinking of QI due to deficiency of the spleen type difficulty in defecation disease, take this concentrated pill, obey after 3 days, the stool rule was separated in one day one, felt more preceding strong in the time of just, separate just unobstructed, dizzy alleviating, it is red that complexion is changeed, symptom takes a turn for the better, and obeys a week, transference cure.
Follow up a case by regular visits to March, not recurrence.
Embodiment 2
Accurately take by weighing each raw material of Chinese medicine that cooks in the ratio of the Radix Astragali 18%, the Rhizoma Atractylodis Macrocephalae 10%, Pericarpium Citri Reticulatae 9%, Rhizoma Cimicifugae 6.5%, Radix Bupleuri 12%, Radix Angelicae Sinensis 10%, Radix Codonopsis 12.5%, Semen Pruni 6%, Fructus Cannabis 16% and amount to 50kg.Wherein, Radix Astragali kg9, Rhizoma Atractylodis Macrocephalae 5kg, Pericarpium Citri Reticulatae 4.5kg, Rhizoma Cimicifugae 3.25kg, Radix Bupleuri 6kg, Radix Angelicae Sinensis 5kg, Radix Codonopsis 6.25kg, Semen Pruni 3kg, Fructus Cannabis 8kg.
Manufacture method is with embodiment 1.
With these a kind of concentrated pill treatment treatment difficulty in defecation after delivery patient 51 examples of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal, cure 33 examples, cure rate 64.7%, 18 examples that take a turn for the better, improvement rate 35.3%, effective percentage 100%.
Model case
Lee, woman, 35 years old, the north Li Gou village peasant of the high village, Laiwu City Laicheng district office.On October 22nd, 2010 is because of section going to a doctor the main suit because of difficulty in defecation comes me puerperal: cuing open the palace before 5 days and produce a boy baby, is that secondary cuts open the palace product, and 5 days puerperal is stool for the first time, is hard and dry, and abdomen does not have distending pain, and diet is normal, does not previously have the constipation history.Examine and see: color is sallow, and skin does not moisten.Light red tongue, thin fur, deficient pulse is puckery.Be diagnosed as sinking of QI due to deficiency of the spleen type difficulty in defecation disease, take this concentrated pill, clothes backs stool day is rule gradually, obey a week after, separated in one day one, separate just unobstructedly, stool does not do.It is red that complexion is changeed, and symptom takes a turn for the better, and takes medicine for 1 week transference cure again.
Follow up a case by regular visits to March, not recurrence.
Embodiment 3
Accurately take by weighing each raw material of Chinese medicine that cooks in the ratio of the Radix Astragali 20%, the Rhizoma Atractylodis Macrocephalae 9%, Pericarpium Citri Reticulatae 10%, Rhizoma Cimicifugae 6%, Radix Bupleuri 13%, Radix Angelicae Sinensis 9%, Radix Codonopsis 11.5%, Semen Pruni 6.5%, Fructus Cannabis 15% and amount to 50kg.Wherein, Radix Astragali kg10, Rhizoma Atractylodis Macrocephalae 4.5kg, Pericarpium Citri Reticulatae 5kg, Rhizoma Cimicifugae 3kg, Radix Bupleuri 6.5kg, Radix Angelicae Sinensis 4.5kg, Radix Codonopsis 5.75kg, Semen Pruni 3.25kg, Fructus Cannabis 7.5kg.
Manufacture method is with embodiment 1.
With these a kind of concentrated pill treatment treatment difficulty in defecation after delivery patient 51 examples of treating sinking of QI due to deficiency of the spleen type difficulty in defecation in puerperal, cure 34 examples, cure rate 66.7%, 23 examples that take a turn for the better, improvement rate 33.3%, effective percentage 100%.
Model case
The side certain, the woman, 30 years old, Laiwu City was avenged wild tourist district room and is done the villager.On May 12nd, 2011 because of puerperal dyschesia go to a doctor the main suit to my section: 10 day previous existence one girl baby, two tires, behind the cesarean section, natural labor history, no chronic disease and constipation history previously.Be hard and dry puerperal always, difficulty when separating, and no abdominal distention and pain, examine and see: shallow complexion, lassitude is had a dizzy spell.Light red tongue, thin fur, deficient and large pulse.Be diagnosed as sinking of QI due to deficiency of the spleen type difficulty in defecation disease, take this concentrated pill, take 5 days after, separate just unobstructedly, big potbellied matter is normal.It is red that complexion is changeed, and the lassitude symptom takes a turn for the better, and head is gradually not dizzy, takes medicine a week transference cure again.Follow up a case by regular visits to March, not recurrence.