CN102784273B - Method for preparing traditional Chinese medicine for treating insomnia caused by high blood pressure - Google Patents

Method for preparing traditional Chinese medicine for treating insomnia caused by high blood pressure Download PDF

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CN102784273B
CN102784273B CN201210270920.6A CN201210270920A CN102784273B CN 102784273 B CN102784273 B CN 102784273B CN 201210270920 A CN201210270920 A CN 201210270920A CN 102784273 B CN102784273 B CN 102784273B
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周晓生
马学英
陈芳
孙大康
王滨
张青青
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Zhou Xiaosheng
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周晓生
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Abstract

The invention provides a method for preparing a traditional Chinese medicine for treating insomnia caused by high blood pressure and belongs to the technical field of preparation methods of traditional Chinese medicines. At present, sedative-hypnotic, anxiolytic or antidepressant drug is usually adopted to treat insomnia caused by high blood pressure and has the defect of great toxic or side effects. The invention adopts the technical scheme that ormer, raddle, white silkworm,tschonosk trillium rhizome, scorpion, cassia seed, oyster,tribulus terrestris, kendyr, hawksbill, nacre, uncaria, rauwolfia,earthworm,periostracum serpentis,arabic cowry shell, chilopod, dung beetle,hedge prinsepia kernel,wall lizard, mantid, valerian,flos albiziae, milkwort,caulis polygoni multiflori, coral, shelled cedar seed,poria with hostood, adonis, amethyst and licorice are placed in water to be soaked, decocted over a slow fire, filtered and deslagged, and the liquid medicine after decoction is the traditional Chinese medicine for treating insomnia caused by high blood pressure. The traditional Chinese medicine has the advantages of simplicity in preparation, small toxic or side effects, short course of treatment, and high cure rate, and can avoid adverse effects due to application of western medicine.

Description

A kind of Chinese medicinal preparation method for the treatment of hypertension insomnia
Technical field
The present invention relates to Chinese medicinal preparation method technical field, more specifically a kind of Chinese medicinal preparation method for the treatment of hypertension insomnia.
Background technology
The insomnia for the treatment of hypertension, generally adopts sedative hypnotic, antianxiety drugs or antidepressants at present.
1, valamin: general quantity toxicity is little, has gastrointestinal symptoms, children's can produce excitement, the allergy such as accidental erythra, have report to cause thrombocytopenia person, its habituation, dependency and addiction and barbiturates seemingly, excessive respiration inhibition, the Blood pressure drop of causing of dosage.
2, Rumi tropine sheet: hepatic and kidney function obstacle person and allergic constitution person are cautious use of or avoid use.Glaucoma patient is avoided use.
3, chloral hydrate: 1. gastrointestinal tract is had to very large stimulation, gastritis and patients w ith peptic ulcer disease should not be used; 2. heavy dose of myocardial contraction that suppresses, suppresses oblongata and breathes and vasomotor center, and Liver and kidney is also had to infringement; 3. long-term prescription can cause dependency, toleration and addiction, and similar chronic alcoholism is given up phenomenon.
4, methaqualone: some patient causes short-term psychological problem, headache, dizziness etc., also has to cause mouth, tongue, numb limbs and tense tendons, can not think first-selected hypnotic.Excessive inhibition is breathed.
5, glutethimide: gastrointestinal is had to stimulation, can cause nausea, erythra, use for a long time addiction, heavy dose of vasomotor center and respiratory center of suppressing.This product has atropine-like effect, can make intestinal and smooth muscle of bladder tension force reduce.
6, phenobarbital: can occur dizziness, the sequela shape such as sleepy after application, tolerate and addiction for a long time with producing, minority causes the allergy such as erythra.
7, bromide: bromide ion is slow through renal excretion, take for a long time easy accumulate poisoning, show as hypomnesis, drowsiness, weak, erythra (bromine acne), child is for a long time with affecting intelligent development, drug withdrawal immediately when poisoning, increases in food salt consumption or adds hydrochlorothiazide and promote excretion.Hypertension, edema, person is forbidden to avoid salt.
8, methyprylon: even have dizzy, nauseating, vomiting, drowsiness, headache, diarrhoea.Excessive can be poisoning, the same barbitalism of rescue method.
9, diazepam: side effect is light, has drowsiness, weak, constipation, cardiopalmus etc., and thrombophlebitis can occur in intravenous injection, and intramuscular injection zest is large.Baby, glaucoma patients and Patients With Myasthenia Gravis forbidding.
Summary of the invention
For overcoming above shortcoming, the object of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of hypertension insomnia.Insomnia claims to be again insomnia, and is to take a kind of syndrome that often must not sleep peacefully as feature.In ancient literature, be called " must not crouch ", " insomnia ".Obstinate insomnia, often with diseases such as headache, dizzy, forgetful, palpitation with a distress feelings.Assertive evidence has void to have reality, said as Zhang Jingyue: " this moon of sleeping, its sage of god also.God peace is slept, and refreshing uneasiness is insomnia, so its uneasy person, one by the disturbing of pathogen, a not enough ear by ying-qi.Have the many excess syndromes of evil person, naivete person is deficiency syndrome all." therefore the treatment of assertive evidence, real person focuses on eliminating evil, and heresy goes god certainly to pacify.Void person focuses on revisal, and eutopic reduction is refreshing must peace.Deficiency and excess is held assorted person under the arm, when examining the place of its deficiency and excess, according to the concrete state of an illness to recuperate under medical treatment it.
etiology and pathogenesis: while showing effect due to hypertension, there is dizziness, headache, tinnitus, the symptom such as dizzy, malaise, and a primary disease.
clinical manifestation: insomnia.Hypertension, dizziness, headache, dizzy, often increase the weight of or bring out primary disease because blood pressure increases.Forgetful, dreaminess, vexed, red tongue, yellow and thin fur, wiry and frequent pulse.
its technical scheme is: get Concha Haliotidis 9 weight portions, Haematitum 6 weight portions, Bombyx Batryticatus 6 weight portions, Rhizoma Trillii Tschonoskii 6 weight portions, Scorpio 1 weight portion, Semen Cassiae 9 weight portions, Concha Ostreae 6 weight portions, Fructus Tribuli 6 weight portions, Herba Apocyni veneti 3 weight portions, Carapax Eretmochelydis 9 weight portions, Concha Margaritifera 9 weight portions, Ramulus Uncariae Cum Uncis 3 weight portions, Radix Rauvolfiae 6 weight portions, Lumbricus 6 weight portions, Periostracum Serpentis 3 weight portions, Concha Erosariae seu Cypraeae 6 weight portions, Scolopendra 1 weight portion, Catharsii molossi 1 weight portion, Nux Prinsepiae 6 weight portions, Gekko Swinhonis 1 weight portion, Mantidis 6 weight portions, Rhizoma et radix valerianae 3 weight portions, Flos Albiziae 3 weight portions, Radix Polygalae 3 weight portions, Caulis Polygoni Multiflori 15 weight portions, Corallium Japonicum Kishinouye 0.3 weight portion, Semen Platycladi 10 weight portions, Poria cum Radix Pini's 9 weight portions, Herba Adonidis 0.3 weight portion, Fluoritum 6 weight portions and Radix Glycyrrhizae 9 weight portions, above 31 taste medicines are put into 1800 ml waters, soak 35 minutes, then slow fire is fried 30 minutes, filter and remove residue obtains 390 milliliters of medicinal liquids, fried medicinal liquid is the Chinese medicine for the treatment of hypertension insomnia.
the advantage of this invention is: this Chinese medicine is made simple, and the herbal toxic effect of making is little, short treating period, and cure rate is high.Can also avoid applying the untoward reaction that Western medicine produces.Concha Haliotidis, Haematitum, Bombyx Batryticatus, Rhizoma Trillii Tschonoskii, Scorpio, Semen Cassiae, Concha Ostreae, Fructus Tribuli, Herba Apocyni veneti, Carapax Eretmochelydis, Concha Margaritifera, Ramulus Uncariae Cum Uncis, Radix Rauvolfiae, Lumbricus, Periostracum Serpentis, Concha Erosariae seu Cypraeae, Scolopendra, Catharsii molossi, Nux Prinsepiae, Gekko Swinhonis, Mantidis, above 21 taste medical instruments have suppressing the hyperactive liver and subsiding YANG, pain relieving relieves dizziness, high fever, infantile convulsions, epilepsy, etc., liver heat removing and eyesight improving, the lung heat clearing heat of dispelling, inducing diuresis to remove edema, the effect that town liver is calmed the nerves.In the process for the treatment of hypertension insomnia, play primary treatment effect, therefore be monarch drug.The above 8 taste medical instruments of Rhizoma et radix valerianae, Flos Albiziae, Radix Polygalae, Caulis Polygoni Multiflori, Corallium Japonicum Kishinouye, Semen Platycladi, Poria cum Radix Pini, Herba Adonidis have resolving stagnation for tranquilization, the appetizing of regulating the flow of vital energy, activating collaterals to relieve pain, purging liver-fire, tranquilizing by nourishing the heart, dispelling wind and removing obstruction in the collateral, calm the nerves compose oneself, removing nebula improving eyesight, tonifying YIN are nourished blood, loosening bowel to relieve constipation, astringing to arrest bleeding, dispel the wind control numbness, tonify deficiency is controlled labor, restoring normal coordination between the heart and kidney, edema removing toxic substances, the antitussive that eliminates the phlegm, the effect of resolving depression profit diaphragm.In the process for the treatment of hypertension insomnia, can assist principal agent performance therapeutical effect, therefore be ministerial drug.Fluoritum: sweet, temperature.Enter the heart, liver two warps.Relieving palpitation arresting convulsion, warming the lung therapeutic method to keep the adverse QI flowing downwards ,Yi Xuenuan palace.Because it can lead the through focus performance of all medicines therapeutical effect, therefore be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate again the toxicity of all medicines, therefore for making medicine.Concha Haliotidis, Haematitum, Bombyx Batryticatus, Rhizoma Trillii Tschonoskii, Scorpio, Semen Cassiae, Concha Ostreae, Fructus Tribuli, Herba Apocyni veneti, Carapax Eretmochelydis, Concha Margaritifera, Ramulus Uncariae Cum Uncis, Radix Rauvolfiae, Lumbricus, Periostracum Serpentis, Concha Erosariae seu Cypraeae, Scolopendra, Catharsii molossi, Nux Prinsepiae, Gekko Swinhonis, Mantidis, Rhizoma et radix valerianae, Flos Albiziae, Radix Polygalae, Caulis Polygoni Multiflori, Corallium Japonicum Kishinouye, Semen Platycladi, Poria cum Radix Pini, Herba Adonidis, Fluoritum, Radix Glycyrrhizae, above 31 medical instruments have QI invigorating emergency treatment of collapse, strengthening the spleen and nourishing the stomach, warm spleen cold expelling, invigorating the spleen and replenishing QI, resolving stagnation for tranquilization, the appetizing of regulating the flow of vital energy, activating collaterals to relieve pain, purging liver-fire, tranquilizing by nourishing the heart, dispelling wind and removing obstruction in the collateral, calm the nerves and compose oneself, removing nebula improving eyesight, tonifying YIN nourishes blood, loosening bowel to relieve constipation, astringing to arrest bleeding, dispel the wind and control numbness, tonify deficiency is controlled labor, restoring normal coordination between the heart and kidney, edema removing toxic substances, antitussive eliminates the phlegm, the effect of resolving depression profit diaphragm.It is the optimum formula for the treatment of hypertension insomnia.Concha Haliotidis: salty, cold, nontoxic.Enter liver, lung, kidney three warps.Suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving, treating stranguria eliminating stagnation, the lung heat clearing heat of dispelling.Haematitum: hardship, cold.Enter liver, stomach, pericardium three warps.Suppressing the hyperactive liver and subsiding YANG, stomach function regulating sending down the abnormal ascending QI, cooling blood for hemostasis.Bombyx Batryticatus: pungent, salty, flat.Enter liver, lung, stomach three warps.Expelling wind to relieve convulsion, dissipating phlegm and resolving masses, heat-clearing and toxic substances removing, heat clearing and damp drying.Rhizoma Trillii Tschonoskii: sweet, acrid, warm, flat.Return Liver Channel.Dispel the wind soothing the liver, promoting regeneration of the tissue and arresting bleeding, analgesia.Scorpio: pungent, salty, flat, poisonous.Enter liver, lung two warps.Expelling wind and relieving convulsion, detoxicating and resolving stagnation of pathogens, removing obstruction in the collateral to relieve pain.Semen Cassiae: sweet, bitter, salty, be slightly cold.Enter liver, kidney, large intestine three warps.Liver heat removing and eyesight improving, loosening bowel to relieve constipation.Concha Ostreae: salty, puckery, cool.Enter liver, kidney two warps.Restrain astringent or styptic treatment for spontaneous sweating, heat clearing away tonifying YIN, yin fluid astringing YANG hyperactivity suppressing, softening and eliminating sputum.Fructus Tribuli: bitter, pungent, be slightly cold.Enter liver, lung two warps.Suppressing the hyperactive liver and subsiding YANG, dispersing the stagnated live-QI to relieve the stagnation of QI, dispelling pathogenic wind for improving eyesight, dispelling wind for relieving itching, eliminating stagnation blood stasis dispelling.Herba Apocyni veneti: sweet, bitter, be slightly cold.Enter the heart, liver, kidney three warps.Suppressing the hyperactive liver to relieve the wind syndrome, inducing diuresis to remove edema, town liver is calmed the nerves, the heat clearing away of inducing sweat.Carapax Eretmochelydis: sweet, salty, cold.Enter the heart, liver two warps.Relieving palpitation suppressing the hyperactive liver, heat-clearing and toxic substances removing.Concha Margaritifera: salty, cold.Enter liver, the heart two warps.The arresting convulsion of calming the nerves, suppressing the hyperactive liver and subsiding YANG, suppressing the hyperactive liver improving eyesight, clearing away heat to stop bleeding, dampness convergence.Ramulus Uncariae Cum Uncis: sweet, be slightly cold.Enter liver, the heart two warps.Endogenous wind stopping relieves the pain, heat clearing away suppressing the hyperactive liver, rash.Radix Rauvolfiae: hardship, cold.Enter liver, lung two warps.The suppressing the hyperactive liver that relieves inflammation or internal heat, heat-clearing and toxic substances removing.Lumbricus: salty, cold.Enter liver, spleen, lung three warps.Heat-clearing and toxic substances removing, suppressing the hyperactive liver to relieve the wind syndrome, relieving cough and asthma, relaxing muscles and tendons and activating QI and blood in the collateral, tonneau urine.Periostracum Serpentis: sweet, salty, flat.Enter liver, spleen two warps.Expelling wind for relieving convulsion, removing nebula to improve visual acuity, removing toxic substances and promoting subsidence of swelling, parasite killing is treated tinea.Concha Erosariae seu Cypraeae: salty, flat.Enter Liver Channel.Heat clearing away suppressing the hyperactive liver, liver heat removing and eyesight improving, suppressing the hyperactive liver is calmed the nerves.Scolopendra: pungent, warm, poisonous.Enter liver, the heart two warps.Endogenous wind stopping relieving convulsion, detoxicating and resolving stagnation of pathogens, dredge the meridian passage, Scolopendra Zou Cuan limit speed.Catharsii molossi: salty, cold, poisonous.Enter stomach, large intestine, liver three warps.Clearing phlegm for calming endogenous wind, heat-clearing and toxic substances removing, drastically removing blood stasis and resolving static blood.Nux Prinsepiae: sweet, cold.Enter the heart, liver two warps.Liver heat removing and eyesight improving, improving acuity of vision and removing nebula, only nosebleed, calms the nerves.Gekko Swinhonis: salty, cold, slightly poisonous.Enter kidney, liver two warps.Relieve dizziness, high fever, infantile convulsions, epilepsy, etc. relieving convulsion, hard masses softening and resolving, wind-expelling pain-stopping, heat-clearing and toxic substances removing.Mantidis: sweet, salty, temperature.Enter the heart, liver, kidney three warps.Tranquillizing the mind by relieving convulsion, promoting blood circulation to remove blood stasis.Rhizoma et radix valerianae: pungent, bitter, temperature, has micro-poison.Enter the heart, liver two warps.Tranquillizing and allaying excitement, blood circulation promoting and blood stasis dispelling, dispelling cold by warming the meridian, treatment urine sudden profuse uterine bleeding.Flos Albiziae: sweet, flat.Enter the heart, liver, spleen three warps.Resolving stagnation for tranquilization, the appetizing of regulating the flow of vital energy, activating collaterals to relieve pain.Radix Polygalae: bitter, pungent, temperature.Enter the heart, kidney, spleen three warps.Restoring normal coordination between the heart and kidney, calms the nerves and nourishes heart, treatment edema, removing toxic substances, the antitussive that eliminates the phlegm, resolving depression profit diaphragm.Caulis Polygoni Multiflori: sweet, micro-hardship, flat.Enter the heart, spleen, liver, kidney four warps.Tranquilizing by nourishing the heart, dispelling wind and removing obstruction in the collateral, treatment carbuncle scrofula, wind skin ulcer scabies.Corallium Japonicum Kishinouye: sweet, flat.Enter liver, the heart two warps.Calm the nerves and compose oneself, removing nebula improving eyesight, hemostasis with astringents.Semen Platycladi: sweet, flat.Enter the heart, liver, spleen three warps.Tranquilizing by nourishing the heart, tonifying YIN nourishes blood, loosening bowel to relieve constipation, astringing to arrest bleeding, dispels the wind and controls numbness.Poria cum Radix Pini: sweet, light, flat.Enter the heart, spleen two warps.Tranquilizing by nourishing the heart, inducing diuresis to remove edema, tonify deficiency is controlled labor.Herba Adonidis: hardship, flat, slightly poisonous.Enter the heart, liver, kidney three warps.Tranquilizing by nourishing the heart, purging liver-fire, inducing diuresis to remove edema.Fluoritum: sweet, temperature.Enter the heart, liver two warps.Relieving palpitation arresting convulsion, warming the lung therapeutic method to keep the adverse QI flowing downwards ,Yi Xuenuan palace.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.
The specific embodiment
Get Concha Haliotidis 9g, Haematitum 6g, Bombyx Batryticatus 6g, Rhizoma Trillii Tschonoskii 6g, Scorpio 1g, Semen Cassiae 9g, Concha Ostreae 6g, Fructus Tribuli 6g, Herba Apocyni veneti 3g, Carapax Eretmochelydis 9g, Concha Margaritifera 9g, Ramulus Uncariae Cum Uncis 3g, Radix Rauvolfiae 6g, Lumbricus 6g, Periostracum Serpentis 3g, Concha Erosariae seu Cypraeae 6g, Scolopendra 1g, Catharsii molossi 1g, Nux Prinsepiae 6g, Gekko Swinhonis 1g, Mantidis 6g, Rhizoma et radix valerianae 3g, Flos Albiziae 3g, Radix Polygalae 3g, Caulis Polygoni Multiflori 15g, Corallium Japonicum Kishinouye 0.3g, Semen Platycladi 10g, Poria cum Radix Pini 9g, Herba Adonidis 0.3g, Fluoritum 6g and Radix Glycyrrhizae 9g, above 31 taste medicines are put into 1800 ml waters, soak 35 minutes, then slow fire is fried 30 minutes, filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of hypertension insomnia.Altogether fried medicinal liquid is 390 milliliters, and when the client need treatment of hypertension insomnia, making fluid temperature is 35 ℃, and each 130 milliliters, oral, three times on the one 2nd is a course for the treatment of, if symptom is still deposited, then takes for second course for the treatment of, so that recovery from illness.
In 397 routine hypertension insomnia patientses, male's 281 examples, account for 70.8%, and women's 116 examples, account for 29.2%.
The range of age of table one, 397 routine hypertension insomnia patientses
Age (year) 26~35 36~45 46~55 41~55
Number of cases 51 202 135 9
Percentage ratio 12.8% 50.9% 34% 2.3%
The curative effect table of table two, 397 routine hypertension insomnia patientses
Curative effect Cure Take a turn for the better Invalid
Number of cases 395 2 Nothing
Percentage ratio 99.5% 0.5% Nothing
Table three, the 397 routine hypertension insomnia patients tables course for the treatment of
Treatment natural law 3~5 6~9 10~14 15~26
Number of cases 13 257 122 5
Percentage ratio 3.3% 64.7% 30.7% 1.3%
Information slip before and after table four, 397 routine hypertension insomnia patients treatments
Figure 44445DEST_PATH_IMAGE002

Claims (1)

1. treat the Chinese medicinal preparation method that hypertension is had a sleepless night for one kind, it is characterized in that: get 9 grams of Concha Haliotidis, 6 grams of Haematitums, 6 grams of Bombyx Batryticatus, 6 grams of Rhizoma Trillii Tschonoskii, 1 gram of Scorpio, 9 grams of Semen Cassiaes, 6 grams of Concha Ostreaes, 6 grams of Fructus Tribulis, 3 grams of Herba Apocyni venetis, 9 grams of Carapax Eretmochelydiss, 9 grams of Concha Margaritiferas, 3 grams of Ramulus Uncariae Cum Uncis, 6 grams of Radix Rauvolfiaes, 6 grams of Lumbricuss, 3 grams of Periostracum Serpentiss, 6 grams of Concha Erosariae seu Cypraeae, 1 gram of Scolopendra, 1 gram of Catharsii molossi, 6 grams of Nux Prinsepiae, 1 gram of Gekko Swinhonis, 6 grams of Mantidiss, 3 grams of Rhizoma et radix valerianaes, 3 grams of Flos Albiziaes, 3 grams of Radix Polygalaes, 15 grams of Caulis Polygoni Multiflori, 0.3 gram, Corallium Japonicum Kishinouye, 10 grams of Semen Platycladi, 9 grams of Poria cum Radix Pinis, 0.3 gram of Herba Adonidis, 9 grams, 6 grams of Fluoritum and Radix Glycyrrhizae, above 31 taste medicines are put into 1800 ml waters, soak 35 minutes, then slow fire is fried 30 minutes, filter and remove residue obtains 390 milliliters of medicinal liquids, fried medicinal liquid is the Chinese medicine for the treatment of hypertension insomnia.
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CN103735657B (en) * 2014-02-19 2015-05-13 杨国兰 Drug for treating insomnia and preparation method thereof
CN103830515B (en) * 2014-04-01 2016-02-17 王凤霞 A kind ofly treat demented medicine and preparation method
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