CN102754825A - Health food for preventing gout - Google Patents
Health food for preventing gout Download PDFInfo
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- CN102754825A CN102754825A CN2012102076735A CN201210207673A CN102754825A CN 102754825 A CN102754825 A CN 102754825A CN 2012102076735 A CN2012102076735 A CN 2012102076735A CN 201210207673 A CN201210207673 A CN 201210207673A CN 102754825 A CN102754825 A CN 102754825A
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Abstract
The invention relates to a health food for preventing gout, which is prepared from the following components by weight: 10-30g of polygonum cuspidatum, 15-60g of polygonum multiflorum stem, 15-60g of sweet potato stem, 25-80g of desmodium and 15-45g of propolis.
Description
Technical field
The invention belongs to field of health care food, particularly a kind of health food and processing method thereof of preventing gout.
Background technology
Along with the development of economic society, income improves constantly per capita, a large amount of absorptions of high purine, high protein, higher fatty acid, low fiber food, and the goat incidence of disease increases year by year.Goat is a metabolic disease; Pathogenic factor is complicated; Gout be purine metabolic disturbance and (or) uric acid excretion reduces caused a kind of crystal-induced arthritis; Uric acid generates too much or the RE uric acid reduce cause in the blood that uric acid raises and in articular cavity deposition form uric acid crystal, cause joint congestion and swelling pain and fall ill.In patient's body, there are a large amount of uric acid to gather, form hyperuricemia,, then can cause arthritic symptom, become the gouty arthritis of outbreak repeatedly if uric acid is deposited on bone and the cartilage.Characteristic acute arthritis, tophus due to clinical manifestation hyperuricemia and the urate crystal deposition forms, tophus property chornic arthritis; And urate nephropathy, uric acid salt lithangiuria etc. can take place, severe patient can occur that disable in the joint, renal insufficiency.Gout is normal and centre type obesity, hyperlipidemia, diabetes, hypertension and cardiovascular and cerebrovascular diseases are concurrent.
The order clinical treatment mainly relies on medicines such as colchicin, nonsteroidal anti-inflammatory drug, glucocorticoid, allopurinol tablet, but with drug therapy certain side effect is arranged all.
The traditional Chinese medical science is thought: the arthralgia due to wind-dampness category.Because human body flesh table channels and collaterals are by the disease and evil impatency, the diseases caused by external factors ailment said due to cold or exposure, the invasion and attack channels and collaterals, qi and blood can not be unimpeded, and cause that the joint is red, swollen, hot, bitterly.Outbreak repeatedly stagnates hemostasis, and the network road blocks, gout calculus deposition, and joint swelling deformation, obstinate pain, pathogen usually intruding into collateral in protracted disease, qi and blood are not smooth, due to hemostasis stagnates, so treatment focuses on disperse blood stasis and dredge collateral.
Dietary therapy is the paracmasis and the hyperuricemia phase of the Primary Care of gout, particularly gout to be superior to drug therapy.Low purine diet can reduce the absorption of purine, reduces blood uric acid concentration.。
Summary of the invention
Primary and foremost purpose of the present invention is to provide a kind of health food that prevents gout.
Another object of the present invention is to provide a kind of processing method of preventing the health food of gout.
The object of the invention is realized through following technical proposals: a kind of health food that prevents gout, the component of being counted by following gram by weight prepares: giant knotweed 10～30 grams, fleece-flower root rattan 15～60 grams, Ipomoea batatas rattan 15～60 grams, desmodium 25～80 grams, propolis 15～45 restrain.
As a kind of preferred version, a kind of health food that prevents gout, the component of being counted by following gram by weight prepares: giant knotweed 20 grams, fleece-flower root rattan 40 grams, Ipomoea batatas rattan 40 grams, desmodium 60 grams, propolis 35 restrain.
A kind of processing method of preventing the health food of gout of the present invention comprises following processing step and process conditions: get and restrain proportioning component giant knotweed 10～30 grams, fleece-flower root rattan 15～60 grams, Ipomoea batatas rattan 15～60 grams, desmodium 25～80 grams by weight, add the water or the organic solvent of 5～10 times of weight; 60～100 ℃ of refluxing extraction of temperature 2-3 time, each 1～3 hour, filter; Filtrating is concentrated into paste; Sneak into propolis 15～45 grams, after the drying, process health food.
The preferred 10-75% ethanolic solution of organic solvent.
The specific embodiment
Embodiment 1
Get giant knotweed 10 gram, fleece-flower root rattan 15 grams, Ipomoea batatas rattan 15 grams, desmodium 25 grams, add the water of 5 times of weight, 60 ℃ of refluxing extraction of temperature 3 times, each 1 hour, to filter, filtrating is concentrated into paste, sneaks into propolis 15 grams, after the drying, processes health food.
Embodiment 2
Get giant knotweed 30 gram, fleece-flower root rattan 60 grams, Ipomoea batatas rattan 60 grams, desmodium 80 grams, add the water of 10 times of weight, 100 ℃ of refluxing extraction of temperature 2 times, each 1 hour, to filter, filtrating is concentrated into paste, sneaks into propolis 45 grams, after the drying, processes health food.
Embodiment 3
Get giant knotweed 20 gram, fleece-flower root rattan 40 grams, Ipomoea batatas rattan 40 grams, desmodium 60 grams, propolis 35 grams, add 25% ethanol of 8 times of weight, 80 ℃ of refluxing extraction of temperature 2 times; Each 1 hour, to filter, filtrating is concentrated into paste; Sneak into propolis 30 grams, after the drying, process health food.
Embodiment 4
Get giant knotweed 22 gram, fleece-flower root rattan 32 grams, Ipomoea batatas rattan 42 grams, desmodium 55 grams, add 35% ethanol of 6 times of weight, 75 ℃ of refluxing extraction of temperature 2 times, each 2 hours, to filter, filtrating is concentrated into paste, sneaks into propolis 35 grams, after the drying, processes health food.
Embodiment 5
Get giant knotweed 25 gram, fleece-flower root rattan 45 grams, Ipomoea batatas rattan 45 grams, desmodium 53 grams, add 40% ethanol of 7 times of weight, 65 ℃ of refluxing extraction of temperature 2 times, each 2 hours, to filter, filtrating is concentrated into paste, sneaks into propolis 35 grams, after the drying, processes health food.
Embodiment 6
Three various dose of food of irritating stomach embodiment 2 in the acute toxicity test per os of mouse are carried out maximum dosage-feeding test in a day; Its result is that total amount reaches 20g/kg in one day; All animals in 7 days still the end overt toxicity reaction and dead appears, the weight of animals does not have significant change yet.Irritating stomach dosage in the long term toxicity test the continuous per os of Wistar rat is 2,4 and 8g/kg,, medication every day once, logotype 90 days continues after stopping to observe 105 days again.In medication the 45th day and detected each item index in 90 days, its result shows: the histopathologic examination to ordinary circumstance, body weight, food ration, peripheral hemogram, liver, renal function, haemocyanin, each main organs coefficient and each main organs thereof of rat does not all have obvious influence.Compare with the normal control group, difference does not have conspicuousness.
Embodiment 7
Gout experimental group 30 examples, the male sex 24 people, women 6 people at 25～66 years old age, in year mean age (51.3 ± 4.1), 7.2 months arthralgia time on average occurs, time range 1～15 month; Average weight 66.14kg, average height 1.63m all meets blood uric acid＞420 μ mol/L, accompanied with hypertension, high fat of blood 5 examples; X-ray film iconography prompting tendon, soft tissue, muscle have tophus deposition person 7 examples, and wherein 2 examples form with the local ulcer of knurl appearance hyperplasia, sinus.
Be equally divided into 2 groups at random, indifference between two groups
Experimental group: use the health food of embodiment 2, every day 3 times, each 50 grams continued for 2 weeks,
Control group: behind the colchicine anti-inflammatory analgesic, oral allopurinol tablet every day 3 times, each 100 milligrams, serve on for 2 weeks.
Diet forbids taking in the food that is rich in purine in a large number, like liver, kidney, brain, roe, sardine, lean meat, beans etc., gives low purine diet control; Many simultaneously drinking-water, every day, amount of drinking water should be at 2000～3000ml, and the amount of urinating maintains about 2500ml, promotes to drain.
Curative effect is judged: 1. recovery from illness: clinical symptom disappearance or basic the disappearance, and blood uric acid is reduced to normally; 2. produce effects: clinical symptoms is obviously improved, the more preceding reduction of blood uric acid＞20%; 3. effective: clinical symptoms takes a turn for the better, the more preceding reduction of blood uric acid＞10%,＜20%; 4. invalid: do not increase the weight of even clinical symptoms has obvious improvement, blood uric acid is with the preceding no significant change of treatment or sb.'s illness took a turn for the worse.
Bad reaction is in obvious lesions of liver and kidney, myocardial damage, dermoreaction, gastrointestinal reaction etc.
Blood uric acid change records before and after the treatment
General curative effect paired observation table
| ? | Recovery from illness | Produce effects | Effectively | Invalid |
| Control group | 15 | 8 | 7 | 10 |
| Experimental group | 23 | 7 | 5 | 5 |
Do not observe bad reaction.
Claims (1)
1. the object of the invention is realized through following technical proposals: a kind of health food that prevents gout, the component of being counted by following gram by weight prepares: giant knotweed 10～30 grams, fleece-flower root rattan 15～60 grams, Ipomoea batatas rattan 15～60 grams, desmodium 25～80 grams, propolis 15～45 restrain.
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| CN2012102076735A CN102754825B (en) | 2012-06-24 | 2012-06-24 | Health food for preventing gout |
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| CN2012102076735A CN102754825B (en) | 2012-06-24 | 2012-06-24 | Health food for preventing gout |
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| CN102754825A true CN102754825A (en) | 2012-10-31 |
| CN102754825B CN102754825B (en) | 2013-10-30 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104957665A (en) * | 2015-07-29 | 2015-10-07 | 李艳青 | Diet therapeutic formula for treating gout and preparation method of diet therapeutic formula |
Citations (4)
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| CN1781541A (en) * | 2004-12-05 | 2006-06-07 | 徐福云 | Chinese medicine preparation for treating gout |
| CN101879221A (en) * | 2010-06-30 | 2010-11-10 | 南京中医药大学 | Medical application of caulis polygoni multiflori |
| CN101926855A (en) * | 2010-08-25 | 2010-12-29 | 肖富洲 | Medicinal tea for reducing uric acid of patient with gout |
| CN102240350A (en) * | 2010-05-10 | 2011-11-16 | 张金荣 | Composition for treating gout and preparation method thereof |
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2012
- 2012-06-24 CN CN2012102076735A patent/CN102754825B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1781541A (en) * | 2004-12-05 | 2006-06-07 | 徐福云 | Chinese medicine preparation for treating gout |
| CN102240350A (en) * | 2010-05-10 | 2011-11-16 | 张金荣 | Composition for treating gout and preparation method thereof |
| CN101879221A (en) * | 2010-06-30 | 2010-11-10 | 南京中医药大学 | Medical application of caulis polygoni multiflori |
| CN101926855A (en) * | 2010-08-25 | 2010-12-29 | 肖富洲 | Medicinal tea for reducing uric acid of patient with gout |
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| 刘绍龑，苗明三: "痛风动物模型研究现状及其中医药治疗特点", 《中医学报》 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104957665A (en) * | 2015-07-29 | 2015-10-07 | 李艳青 | Diet therapeutic formula for treating gout and preparation method of diet therapeutic formula |
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Owner name: NINGBO YINZHOU FURUIDA BIOTECHNOLOGY CO., LTD. Free format text: FORMER OWNER: NINGBO YINZHOU HAOSI RUIPU BIOTECHNOLOGY CO., LTD. Effective date: 20130929 |
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